Category: 415918-91-1

In organic chemistry, atoms other than carbon and hydrogen are generally referred to as heteroatoms. The most common heteroatoms are nitrogen, oxygen and sulfur. Now I present to you an article called Copper-Catalyzed Asymmetric Borylative Cyclization of Cyclohexadienone-Containing 1,6-Dienes, published in 2020, which mentions a compound: 415918-91-1, mainly applied to copper catalyzed asym borylative cyclization cyclohexadienone diene; borylated tetrahydrobenzofuranone preparation; crystal structure borylated tetrahydrobenzofuranone; mol structure borylated tetrahydrobenzofuranone, Category: esters-buliding-blocks.

Due to the low reactivity of 1,6-dienes and the challenge of selectively differentiating such two olefins, the development of metal-catalyzed asym. cyclization of 1,6-dienes remains largely underdeveloped. Herein, the authors describe the 1st Cu(I)-catalyzed asym. borylative cyclization of cyclohexadienone-tethered terminal alkenes (1,6-dienes) via a tandem process: the regioselective borocupration of the electron-rich terminal alkene and subsequent conjugate addition of stereospecific secondary alkyl-Cu(I) to the electron-deficient cyclohexadienone, affording enantioenriched bicyclic skeletons bearing three contiguous stereocenters in all cis-form. Meanwhile, this mild catalytic protocol is generally compatible with a wide range of functional groups, which allows further facile conversion of the cyclization products.

From this literature《Copper-Catalyzed Asymmetric Borylative Cyclization of Cyclohexadienone-Containing 1,6-Dienes》,we know some information about this compound(415918-91-1)Category: esters-buliding-blocks, but this is not all information, there are many literatures related to this compound(415918-91-1).

Reference:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

The three-dimensional configuration of the ester heterocycle is basically the same as that of the carbocycle. Compound: (11bR)-N,N-Bis[(1R)-1-phenylethyl]dinaphtho[2,1-d:1′,2′-f][1,3,2]dioxaphosphepin-4-amine(SMILESS: C[C@@H](N(P1OC2=CC=C3C=CC=CC3=C2C4=C5C=CC=CC5=CC=C4O1)[C@@H](C6=CC=CC=C6)C)C7=CC=CC=C7,cas:415918-91-1) is researched.Application In Synthesis of 2,5-Diphenyloxazole. The article 《Tandem Iridium Catalysis as a General Strategy for Atroposelective Construction of Axially Chiral Styrenes》 in relation to this compound, is published in Journal of the American Chemical Society. Let’s take a look at the latest research on this compound (cas:415918-91-1).

The first tandem iridium catalysis as a general strategy for the synthesis of axially chiral styrenes enabled by Asym. Allylic Substitution-Isomerization (AASI) using cinnamyl carbonate analogs as electrophiles and naphthols as nucleophiles. Axially chiral styrenes were generated through two independent iridium-catalytic cycles: iridium-catalyzed asym. allylic substitution and in-situ isomerization via stereospecific 1,3-hydride transfer catalyzed by the same iridium catalyst. Both exptl. and computational studies demonstrated that the isomerization proceeded by iridium-catalyzed benzylic C-H bond oxidative addition, followed by terminal C-H reductive elimination. Amid the central-to-axial chirality transfer, the hydroxyl of naphthol played a crucial role in ensured the stereospecificity by coordinating with the Ir(I) center. The process accommodated broad functional group compatibility. The products were generated in excellent yields with excellent to high enantioselectivities, which would be transformed to various axially chiral mols.

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Reference:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Most of the compounds have physiologically active properties, and their biological properties are often attributed to the heteroatoms contained in their molecules, and most of these heteroatoms also appear in cyclic structures. A Journal, Article, Research Support, Non-U.S. Gov’t, Journal of Organic Chemistry called Synthesis of Chiral Homoallylic Nitriles by Iridium-Catalyzed Allylation of Cyanoacetates, Author is Matsunami, Asuka; Takizawa, Kazuki; Sugano, Shogo; Yano, Yusuke; Sato, Hiroaki; Takeuchi, Ryo, which mentions a compound: 415918-91-1, SMILESS is C[C@@H](N(P1OC2=CC=C3C=CC=CC3=C2C4=C5C=CC=CC5=CC=C4O1)[C@@H](C6=CC=CC=C6)C)C7=CC=CC=C7, Molecular C36H30NO2P, SDS of cas: 415918-91-1.

A synthesis of chiral homoallylic nitriles by the iridium-catalyzed allylation of cyanoacetates followed by Krapcho demethoxycarbonylation has been developed. A wide range of homoallylic nitriles were obtained with a high enantioselectivity (>95-99% ee). These compounds are useful chiral building blocks because further synthetic elaboration starting from a nitrile or terminal alkene is possible.

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Reference:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Safety of (11bR)-N,N-Bis[(1R)-1-phenylethyl]dinaphtho[2,1-d:1′,2′-f][1,3,2]dioxaphosphepin-4-amine. So far, in addition to halogen atoms, other non-metallic atoms can become part of the aromatic heterocycle, and the target ring system is still aromatic. Compound: (11bR)-N,N-Bis[(1R)-1-phenylethyl]dinaphtho[2,1-d:1′,2′-f][1,3,2]dioxaphosphepin-4-amine, is researched, Molecular C36H30NO2P, CAS is 415918-91-1, about Iridium-catalyzed regio- and enantioselective allylic alkylation of fluorobis(phenylsulfonyl)methane.

Highly regio- and enantioselective allylic alkylation of fluorobis(phenylsulfonyl)methane (FBSM) has been realized by [Ir(COD)Cl]2/phosphoramidite, affording enantiopure fluorobis(phenylsulfonyl)methylated compounds bearing a terminal alkene, which could be converted to monofluoro-methylated ibuprofen in just two steps without loss of the optical purity (95% ee).

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Reference:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

The preparation of ester heterocycles mostly uses heteroatoms as nucleophilic sites, which are achieved by intramolecular substitution or addition reactions. Compound: (11bR)-N,N-Bis[(1R)-1-phenylethyl]dinaphtho[2,1-d:1′,2′-f][1,3,2]dioxaphosphepin-4-amine( cas:415918-91-1 ) is researched.HPLC of Formula: 415918-91-1.Shu, Chutian; Hartwig, John F. published the article 《Synthesis of allylic ethers: Iridium-catalyzed intermolecular allylic etherification with aliphatic alkoxides: Asymmetric synthesis of dihydropyrans and dihydrofurans》 about this compound( cas:415918-91-1 ) in Angewandte Chemie, International Edition. Keywords: allylic carbonate alkoxide substitution; ether allylic asym preparation; iridium substitution catalyst; dialkenyl ether asym preparation metathesis; furan asym preparation; pyran asym preparation. Let’s learn more about this compound (cas:415918-91-1).

Hindered chiral ethers with one or two stereocenters, e.g., I, are now readily available by allylic etherification of primary and secondary alkoxides. When an Ir-phosphoramidite complex is used as the catalyst, the reaction proceeds with high regio-, enantio-, and diastereoselectivity.

If you want to learn more about this compound((11bR)-N,N-Bis[(1R)-1-phenylethyl]dinaphtho[2,1-d:1′,2′-f][1,3,2]dioxaphosphepin-4-amine)HPLC of Formula: 415918-91-1, you may wish to communicate with the author of the article,or consult the relevant literature related to this compound(415918-91-1).

Reference:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

In general, if the atoms that make up the ring contain heteroatoms, such rings become heterocycles, and organic compounds containing heterocycles are called heterocyclic compounds. An article called A highly effective phosphoramidite ligand for asymmetric allylic substitution, published in 2004-04-26, which mentions a compound: 415918-91-1, Name is (11bR)-N,N-Bis[(1R)-1-phenylethyl]dinaphtho[2,1-d:1′,2′-f][1,3,2]dioxaphosphepin-4-amine, Molecular C36H30NO2P, Synthetic Route of C36H30NO2P.

Very high enantioselectivity has been achieved both in the copper-catalyzed alkylation of allylic substrates by Grignard and organozinc reagents and in the iridium-catalyzed amination of cinnamyl carbonate by employing a very efficient phosphoramidite. E.g., reaction of (E)-PhCH:CHCH2Br and Et2Zn in presence of copper(I) 2-thiophenecarboxylate and phosphoramidite ligand I gave allyl derivative II (83% conversion).

If you want to learn more about this compound((11bR)-N,N-Bis[(1R)-1-phenylethyl]dinaphtho[2,1-d:1′,2′-f][1,3,2]dioxaphosphepin-4-amine)Synthetic Route of C36H30NO2P, you may wish to communicate with the author of the article,or consult the relevant literature related to this compound(415918-91-1).

Reference:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Heterocyclic compounds can be divided into two categories: alicyclic heterocycles and aromatic heterocycles. Compounds whose heterocycles in the molecular skeleton cannot reflect aromaticity are called alicyclic heterocyclic compounds. Compound: 415918-91-1, is researched, Molecular C36H30NO2P, about Direct, iridium-catalyzed enantioselective and regioselective allylic etherification with aliphatic alcohols, the main research direction is etherification allylic stereoselective regioselective alc iridium catalyst.Recommanded Product: 415918-91-1.

Iridium-catalyzed allylations yield α chiral ether derivatives directly from aliphatic alcs. with a simple alkali metal base. These reactions form ethers from primary, secondary, and tertiary alkoxides with high enantioselectivity. Byproducts from isomerization were suppressed by the use of an alkyne additive.

If you want to learn more about this compound((11bR)-N,N-Bis[(1R)-1-phenylethyl]dinaphtho[2,1-d:1′,2′-f][1,3,2]dioxaphosphepin-4-amine)Recommanded Product: 415918-91-1, you may wish to communicate with the author of the article,or consult the relevant literature related to this compound(415918-91-1).

Reference:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

So far, in addition to halogen atoms, other non-metallic atoms can become part of the aromatic heterocycle, and the target ring system is still aromatic.Maksymowicz, Rebecca M.; Roth, Philippe M. C.; Thompson, Amber L.; Fletcher, Stephen P. researched the compound: (11bR)-N,N-Bis[(1R)-1-phenylethyl]dinaphtho[2,1-d:1′,2′-f][1,3,2]dioxaphosphepin-4-amine( cas:415918-91-1 ).Product Details of 415918-91-1.They published the article 《Hydrometallation-asymmetric conjugate addition: application to complex molecule synthesis》 about this compound( cas:415918-91-1 ) in Chemical Communications (Cambridge, United Kingdom). Keywords: alkene hydrometalation stereoselective conjugate addition enone steroid copper catalyst. We’ll tell you more about this compound (cas:415918-91-1).

Copper catalysis allows alkyl zirconium species, generated in situ from alkenes, to undergo conjugate addition reactions. A hydrometalation-catalytic asym. 1,4-addition was used to synthesize either enantiomer of a natural product in one step from com. available materials. Hydrometalation-addition sequences applied to steroids containing a cross-conjugated dienone or 1,6-acceptor give highly functionalized products.

If you want to learn more about this compound((11bR)-N,N-Bis[(1R)-1-phenylethyl]dinaphtho[2,1-d:1′,2′-f][1,3,2]dioxaphosphepin-4-amine)Product Details of 415918-91-1, you may wish to communicate with the author of the article,or consult the relevant literature related to this compound(415918-91-1).

Reference:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Reference of (11bR)-N,N-Bis[(1R)-1-phenylethyl]dinaphtho[2,1-d:1′,2′-f][1,3,2]dioxaphosphepin-4-amine. Aromatic compounds can be divided into two categories: single heterocycles and fused heterocycles. Compound: (11bR)-N,N-Bis[(1R)-1-phenylethyl]dinaphtho[2,1-d:1′,2′-f][1,3,2]dioxaphosphepin-4-amine, is researched, Molecular C36H30NO2P, CAS is 415918-91-1, about Controllable Si-C Bond Activation Enables Stereocontrol in the Palladium-Catalyzed [4+2] Annulation of Cyclopropenes with Benzosilacyclobutanes. Author is Wang, Xing-Ben; Zheng, Zhan-Jiang; Xie, Jia-Le; Gu, Xing-Wei; Mu, Qiu-Chao; Yin, Guan-Wu; Ye, Fei; Xu, Zheng; Xu, Li-Wen.

A novel and unusual Pd-catalyzed [4+2] annulation of cyclopropenes with benzosilacyclobutanes is reported. This reaction occurred through chemoselective Si-C(sp2) bond activation in synergy with ring expansion/insertion of cyclopropenes to form new C(sp2)-C(sp3) and Si-C(sp3) bonds. An array of previously elusive bicyclic skeleton with high strain, silabicyclo[4.1.0]heptanes, were formed in good yields with excellent diastereoselectivity under mild conditions. An asym. version of the reaction with a chiral phosphoramidite ligand furnished a variety of chiral bicyclic silaheterocycle derivatives with good enantioselectivity (up to 95.5:4.5 er). Owing to the mild reaction conditions, the good stereoselectivity profile, and the ready availability of the functionalized precursors, this process constitutes a useful and straightforward strategy for the synthesis of densely functionalized silacycles.

Here is a brief introduction to this compound(415918-91-1)Reference of (11bR)-N,N-Bis[(1R)-1-phenylethyl]dinaphtho[2,1-d:1′,2′-f][1,3,2]dioxaphosphepin-4-amine, if you want to know about other compounds related to this compound(415918-91-1), you can read my other articles.

Reference:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Name: (11bR)-N,N-Bis[(1R)-1-phenylethyl]dinaphtho[2,1-d:1′,2′-f][1,3,2]dioxaphosphepin-4-amine. Aromatic heterocyclic compounds can also be classified according to the number of heteroatoms contained in the heterocycle: single heteroatom, two heteroatoms, three heteroatoms and four heteroatoms. Compound: (11bR)-N,N-Bis[(1R)-1-phenylethyl]dinaphtho[2,1-d:1′,2′-f][1,3,2]dioxaphosphepin-4-amine, is researched, Molecular C36H30NO2P, CAS is 415918-91-1, about Iridium-Catalyzed Enantioselective Allylic Substitution of Enol Silanes from Vinylogous Esters and Amides. Author is Chen, Ming; Hartwig, John F..

The enol silanes of vinylogous esters and amides are classic dienes for Diels-Alder reactions. Here, we report their reactivity as nucleophiles in Ir-catalyzed, enantioselective allylic substitution reactions. A variety of allylic carbonates react with these nucleophiles to give allylated products in good yields with high enantioselectivities and excellent branched-to-linear ratios. These reactions occur with KF or alkoxide as the additive, but mechanistic studies suggest that these additives do not activate the enol silanes. Instead, they serve as bases to promote the cyclometalation to generate the active Ir catalyst. The carbonate anion, which was generated from the oxidative addition of the allylic carbonate, likely activates the enol silanes to trigger their activity as nucleophiles for reactions with the allyliridium electrophile. The synthetic utility of this method was illustrated by the synthesis of the anti-muscarinic drug, fesoterodine, I.

Here is a brief introduction to this compound(415918-91-1)Name: (11bR)-N,N-Bis[(1R)-1-phenylethyl]dinaphtho[2,1-d:1′,2′-f][1,3,2]dioxaphosphepin-4-amine, if you want to know about other compounds related to this compound(415918-91-1), you can read my other articles.

Reference:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics