Category: 4033-88-9

Tudge, Matthew; Mashima, Hiroko; Savarin, Cecile; Humphrey, Guy; Davies, Ian published an article on February 4 ,2008. The article was titled 《Facile reduction of malonate derivatives using NaBH4/Br2: an efficient route to 1,3-diols》, and you may find the article in Tetrahedron Letters.Category: esters-buliding-blocks The information in the text is summarized as follows:

Borane-dimethoxyethane generated from sodium borohydride-bromine mixtures efficiently reduces a wide range of malonate derivatives to the corresponding 1,3-diols. This new reagent system represents a milder alternative to current methods available, providing the requisite 1,3-diols in higher yields over shorter reaction times. In the experimental materials used by the author, we found Dimethyl 2-(4-nitrophenyl)malonate(cas: 4033-88-9Category: esters-buliding-blocks)

Dimethyl 2-(4-nitrophenyl)malonate(cas: 4033-88-9) belongs to esters. They are important in biology, being one of the main classes of lipids and comprising the bulk of animal fats and vegetable oils.Category: esters-buliding-blocks Polyesters are important plastics, with monomers linked by ester moieties.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Selvakumar, N.; Azhagan, A. Malar; Srinivas, D.; Krishna, G. Gopi published their research in Tetrahedron Letters on December 9 ,2002. The article was titled 《A direct synthesis of 2-arylpropenoic acid esters having nitro groups in the aromatic ring: a short synthesis of (±)-coerulescine and (±)-horsfiline》.Reference of Dimethyl 2-(4-nitrophenyl)malonate The article contains the following contents:

A short synthesis of 2-arylpropenoic acid esters that possess nitro groups in their Ph ring using common and less expensive reagents is described. The usefulness of this methodol. is substantiated by the efficient total syntheses of (±)-coerulescine (I) and (±)-horsfiline from the 2-arylpropenoic acid esters obtained. In the experimental materials used by the author, we found Dimethyl 2-(4-nitrophenyl)malonate(cas: 4033-88-9Reference of Dimethyl 2-(4-nitrophenyl)malonate)

Dimethyl 2-(4-nitrophenyl)malonate(cas: 4033-88-9) belongs to esters. They are important in biology, being one of the main classes of lipids and comprising the bulk of animal fats and vegetable oils. They perform as high-grade solvents for a broad array of plastics, plasticizers, resins, and lacquers, and are one of the largest classes of synthetic lubricants on the commercial market.Reference of Dimethyl 2-(4-nitrophenyl)malonate

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Product Details of 4033-88-9On May 27, 2002, Selvakumar, N.; Yadi Reddy, B.; Sunil Kumar, G.; Iqbal, Javed published an article in Tetrahedron Letters. The article was 《Dimethyl malonate as a one-carbon source: a novel method of introducing carbon substituents onto aromatic nitro compounds. [Erratum to document cited in CA136:247364]》. The article mentions the following:

The synthesis of mostly methylated aromatic nitro compound using similar didecarboxylation has been reported by: Gurjar, M.; Reddy, D. S.;; Murugaiah, A.; Murugaiah, S. Synthesis 2000, 1659. The results came from multiple reactions, including the reaction of Dimethyl 2-(4-nitrophenyl)malonate(cas: 4033-88-9Product Details of 4033-88-9)

Dimethyl 2-(4-nitrophenyl)malonate(cas: 4033-88-9) belongs to esters. They are important in biology, being one of the main classes of lipids and comprising the bulk of animal fats and vegetable oils.Product Details of 4033-88-9 They perform as high-grade solvents for a broad array of plastics, plasticizers, resins, and lacquers, and are one of the largest classes of synthetic lubricants on the commercial market. Polyesters are important plastics, with monomers linked by ester moieties.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

The author of 《Phenylmalonic and nitrophenylmalonic acids and esters》 were Basterfield, S.; Hamilton, L. A.. And the article was published in Trans. Roy. Soc. Can. III in 1933. Electric Literature of C11H11NO6 The author mentioned the following in the article:

Shaking PhCH(CO2Me)2 (I) in Et2O with dilute aqueous NaOH for 1 hr. at room temperature gives an aqueous alk. solution which with acid gives 80-90% of PhCH(CO2H)2 (II). The method of Wislicenus (Ber. 27, 1091(1894)) gives only a 25% yield. I with concentrated HNO3 and concentrated H2SO4 gives Me p-nitrophenylmalonate (III), m. 95°. III on hydrolysis by the above method gives only p-O2NC6H4CH2CO2H. II with concentrated HNO3 and concentrated H2SO4 gives o-nitrophenylmalonic acid, m. 133° (decomposition). Contrary to expectations p-O2NC6H4CH2CO2Me does not condense with (OC2Me)2 (cf. Rising and Stieglitz, C. A. 12, 908). p-EtOOCNHC6H4CH2CO2Me condenses with (CO2Me)2 to give Me p-carbethoxyaminophenylmalonate, viscous oil, b5 110°. Reduction of 2,4(O2N)2C6H3CH(CO2Me)2 (IV) with (NH4)2S gives 2 isomeric Me nitroaminophenylmalonates, m. 131° and 190°. IV on hydrolysis does not give the expected acid. The experimental process involved the reaction of Dimethyl 2-(4-nitrophenyl)malonate(cas: 4033-88-9Electric Literature of C11H11NO6)

Dimethyl 2-(4-nitrophenyl)malonate(cas: 4033-88-9) belongs to esters.Electric Literature of C11H11NO6 They are important in biology, being one of the main classes of lipids and comprising the bulk of animal fats and vegetable oils.Esters typically have a pleasant smell; those of low molecular weight are commonly used as fragrances and are found in essential oils and pheromones.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Gierczyk, Blazej; Leska, Boguslawa; Brzezinski, Bogumil; Schroeder, Grzegorz published their research in Supramolecular Chemistry on December 31 ,2002. The article was titled 《Podand solvents for organic reactions》.Synthetic Route of C11H11NO6 The article contains the following contents:

Three tris(oxaalkyl)phenylsilanes and two tris(oxaalkyl) phosphates were used as podand solvents in kinetic studies of proton transfer reactions between C-acids: di-Me (4-nitrophenyl)malonate or phenyl-4-nitrophenylcyanomethane and the strong base: 7-methyl-1,5,7-triazabicyclo[4.4.0]dec-5-ene (MTBD). The acceptor numbers were measured for all new podand solvents. The kinetic parameters for studied reactions were obtained, discussed and compared with those of acetonitrile and OP(OEt)3 as nonpodand solvents. The second order rate constants strongly decreased and the energy barrier increased for the proton transfer reaction in podand solvents. Spectroscopic observations showed that ionic products were strongly stabilized and therefore their lifetime was relatively long. The podand solvents formed the ionic channels in which ionic products are strongly solvated.Dimethyl 2-(4-nitrophenyl)malonate(cas: 4033-88-9Synthetic Route of C11H11NO6) was used in this study.

Dimethyl 2-(4-nitrophenyl)malonate(cas: 4033-88-9) belongs to esters.Synthetic Route of C11H11NO6 They are important in biology, being one of the main classes of lipids and comprising the bulk of animal fats and vegetable oils.Esters typically have a pleasant smell; those of low molecular weight are commonly used as fragrances and are found in essential oils and pheromones.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Electric Literature of C11H11NO6On March 18, 2022, Lee, Richmond; Eric Chao, Chi Bong; Ban, Xu; Tan, Siu Min; Yu, Haibo; Hyland, Christopher J. T.; Tan, Choon-Hong published an article in Journal of Organic Chemistry. The article was 《Direct SN2 or SN2X Manifold-Mechanistic Study of Ion-Pair-Catalyzed Carbon(sp3)-Carbon(sp3) Bond Formation》. The article mentions the following:

D. functional theory (DFT) is used in this work to predict the mechanism for constructing congested quaternary-quaternary carbon(sp3)-carbon(sp3) bonds in a pentanidium-catalyzed substitution reaction. Computational mechanistic studies were carried out to investigate the proposed SN2X manifold, which consists of two primary elementary steps: halogen atom transfer (XAT) and subsequent SN2. For the first calculated model on original exptl. substrates, XAT reaction barriers were more kinetically competitive than an SN2 pathway and connect to thermodynamically stable intermediates. Extensive computational screening modeling was then done on various substrate combinations designed to study the steric influence and to understand the mechanistic rationale, and calculations reveal that sterically congested substrates prefer the SN2X manifold over SN2. Different halides as leaving groups were also screened, and it was found that the reactivity increases in the order of I > Br > Cl > F, in agreement with the strength of C-X bonds. However, DFT modeling suggests that chlorides can be a viable substrate for the SN2X process, which should be further explored exptl. ONIOM calculations on the full catalyst model predicted the correct stereochem. outcome, and further catalyst screening with cationic Me4N+ and K+ predicted that pentanidium is still the choice for SN2X C-C bond formation. In the experiment, the researchers used Dimethyl 2-(4-nitrophenyl)malonate(cas: 4033-88-9Electric Literature of C11H11NO6)

Dimethyl 2-(4-nitrophenyl)malonate(cas: 4033-88-9) belongs to esters. They are important in biology, being one of the main classes of lipids and comprising the bulk of animal fats and vegetable oils.Electric Literature of C11H11NO6 They perform as high-grade solvents for a broad array of plastics, plasticizers, resins, and lacquers, and are one of the largest classes of synthetic lubricants on the commercial market. Polyesters are important plastics, with monomers linked by ester moieties.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Akkirala, Venkat Narsaiah published their research in Catalysis Letters on February 29 ,2008. The article was titled 《Microwave-promoted alkylation of halonitrobenzene with malonates in solvent-free medium》.Quality Control of Dimethyl 2-(4-nitrophenyl)malonate The article contains the following contents:

The alkylation on different substituted halonitrobenzenes were demonstrated with various malonates under the influence of microwaves irradiation The reactions were catalyzed by potassium carbonate and benzyltriethylammoniumchloride. The salient features of this methodol. are mild reaction conditions, high regio-selectivity, rapid conversions, solvent-free medium and easy isolation of products. The experimental part of the paper was very detailed, including the reaction process of Dimethyl 2-(4-nitrophenyl)malonate(cas: 4033-88-9Quality Control of Dimethyl 2-(4-nitrophenyl)malonate)

Dimethyl 2-(4-nitrophenyl)malonate(cas: 4033-88-9) belongs to esters. They are important in biology, being one of the main classes of lipids and comprising the bulk of animal fats and vegetable oils.Quality Control of Dimethyl 2-(4-nitrophenyl)malonate They perform as high-grade solvents for a broad array of plastics, plasticizers, resins, and lacquers, and are one of the largest classes of synthetic lubricants on the commercial market.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

HPLC of Formula: 4033-88-9On March 30, 1999, Schroeder, Grzegorz; Leska, Boguslawa; Bartl, Franz; Rozalski, Bartosz; Brzezinski, Bogumil published an article in Journal of Molecular Structure. The article was 《Proton transfer reaction from some C-H acids to N-bases in polar aprotic solvents》. The article mentions the following:

The deprotonation reactions of di-Me (4-nitrophenyl)malonate and 4-bromophenyl-4-nitrophenylcyanomethane by tris[2-(2-methoxyethoxy)ethyl]amine, tributylamine and cryptand 222 were studied in polar aprotic solvents such as DMSO and acetonitrile by the kinetic, FT-IR and 1H NMR spectroscopic methods. The mechanisms of the proton transfer reactions are discussed. In addition to this study using Dimethyl 2-(4-nitrophenyl)malonate, there are many other studies that have used Dimethyl 2-(4-nitrophenyl)malonate(cas: 4033-88-9HPLC of Formula: 4033-88-9) was used in this study.

Dimethyl 2-(4-nitrophenyl)malonate(cas: 4033-88-9) belongs to esters.HPLC of Formula: 4033-88-9 They are important in biology, being one of the main classes of lipids and comprising the bulk of animal fats and vegetable oils.Esters typically have a pleasant smell; those of low molecular weight are commonly used as fragrances and are found in essential oils and pheromones.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Name: Dimethyl 2-(4-nitrophenyl)malonateOn October 31, 1996 ,《Proton transfer reactions from dimethyl (4-nitrophenyl)malonate to N-bases in acetonitrile》 was published in Journal of Molecular Structure. The article was written by Schroeder, Grzegorz; Brzezinski, Bogumil; Jarczewski, Arnold; Grech, Eugeniusz; Milart, Piotr. The article contains the following contents:

Deprotonations of di-Me (4-nitrophenyl)malonate (C-acid) by 7-methyl-1,5,7-triazabicyclo[4.4.0]dec-5-ene (MTBD), 1,5,7-triazabicyclo[4.4.0]dec-5-ene (TBD) and 1,8-bis(dimethylamino)naphthalene (DMAN) in acetonitrile were studied by kinetic as well as FTIR and 1H NMR spectroscopic methods. In the 1:1 mixture of C-acid with DMAN no proton transfer was found. The N-bases with guanidine-like character deprotonate C-acid in the acetonitrile solution quant. The mechanisms of proton transfer reactions are discussed.Dimethyl 2-(4-nitrophenyl)malonate(cas: 4033-88-9Name: Dimethyl 2-(4-nitrophenyl)malonate) was used in this study.

Dimethyl 2-(4-nitrophenyl)malonate(cas: 4033-88-9) belongs to esters. They are important in biology, being one of the main classes of lipids and comprising the bulk of animal fats and vegetable oils.Name: Dimethyl 2-(4-nitrophenyl)malonate They perform as high-grade solvents for a broad array of plastics, plasticizers, resins, and lacquers, and are one of the largest classes of synthetic lubricants on the commercial market. Polyesters are important plastics, with monomers linked by ester moieties.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Recommanded Product: Dimethyl 2-(4-nitrophenyl)malonateOn May 18, 1998 ,《Solvent effects for proton transfer reaction from dimethyl (4-nitrophenyl)malonate to cis-1,2-bis(diethylaminomethyl)cyclohexane》 appeared in Journal of Molecular Structure. The author of the article were Schroeder, Grzegorz; Leska, Boguslawa; Brzezinski, Boguml. The article conveys some information:

The influence of polar aprotic solvents: DMSO, AN and HMPA on the kinetics of proton transfer reactions from dimethyl(4-nitrophenyl)malonate (C-acid) to cis-1,2-bis-(diethylaminomethyl)cyclohexane (DEAMCH) was studied. On the basis of the kinetic parameters obtained, the multistep mechanism of deprotonation processes and the influence of solvation on transition state were discussed. In the experiment, the researchers used Dimethyl 2-(4-nitrophenyl)malonate(cas: 4033-88-9Recommanded Product: Dimethyl 2-(4-nitrophenyl)malonate)

Dimethyl 2-(4-nitrophenyl)malonate(cas: 4033-88-9) belongs to esters. Esters are more polar than ethers but less polar than alcohols. They participate in hydrogen bonds as hydrogen-bond acceptors, but cannot act as hydrogen-bond donors, unlike their parent alcohols. Recommanded Product: Dimethyl 2-(4-nitrophenyl)malonate

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics