Category: 37942-79-3

Radchenko, Dmytro S. published the artcileCyclobutane-Derived Diamines: Synthesis and Molecular Structure, Related Products of esters-buliding-blocks, the main research area is cyclobutane diamine preparation mol structure.

Cyclobutane diamines (i.e., cis- and trans-1,3-diaminocyclobutane, 6-amino-3-azaspiro[3.3]heptane, and 3,6-diaminospiro[3.3]heptane) are considered as promising sterically constrained diamine building blocks for drug discovery. An approach to the syntheses of their Boc-monoprotected derivatives has been developed aimed at the preparation of multigram amounts of the compounds These novel synthetic schemes exploit classical malonate alkylation chem. for the construction of cyclobutane rings. The conformational preferences of the cyclobutane diamine derivatives have been evaluated by X-ray diffraction and compared with the literature data on sterically constrained diamines, which are among the constituents of com. available drugs.

Journal of Organic Chemistry published new progress about Alicyclic amines Role: SPN (Synthetic Preparation), PREP (Preparation) (diamines). 37942-79-3 belongs to class esters-buliding-blocks, name is Dimethyl spiro[3.3]heptane-2,6-dicarboxylate, and the molecular formula is C11H16O4, Related Products of esters-buliding-blocks.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Weatherhead, Robin A. published the artcileSynthesis of conformationally constrained diaminodicarboxylic acid derivatives, Category: esters-buliding-blocks, the main research area is aminodicarboxylic di cyclic acid synthesis conformation conformer crystal structure.

Functionally protected forms of three conformationally constrained diaminodicarboxylic acids were synthesized and characterized. 2,2′-Diaminospiro[3.3]heptane-2,2′-dicarboxylic acid, an analog of diaminopimelic acid, was prepared in racemic form and the structure established by X-ray crystallog. anal. of the Me ester hydrochloride. Trans-1,4-Diaminocyclohexane-1,4-dicarboxylic acid was prepared and its structure established by X-ray crystallog. anal. of the corresponding Cbz-protected Et ester. Cis- And trans-2,6-diamino-1,2,3,5,6,7-hexahydro-s-indacene-2,6-dicarboxylic acids were synthesized and the structures assigned by X-ray crystallog. anal. of the corresponding Boc-protected Et ester and Cbz-protected Et ester, resp.

Journal of Organic Chemistry published new progress about Conformation. 37942-79-3 belongs to class esters-buliding-blocks, name is Dimethyl spiro[3.3]heptane-2,6-dicarboxylate, and the molecular formula is C11H16O4, Category: esters-buliding-blocks.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics