Category: 3319-31-1

On June 1, 2022, Mulero, A.; Cachadina, I.; Vegas, A. published an article.Quality Control of Tris(2-ethylhexyl) benzene-1,2,4-tricarboxylate The title of the article was Recommended Correlations for the Surface Tension of Aromatic, Polyfunctional, and Glyceride Esters. And the article contained the following:

Surface tension values for 79 esters, including aromatics, polyfunctional, and glycerides, have been compiled from databases, books, and papers in the literature. The data have been carefully screened, and finally, 1517 values were selected. Each fluid dataset has been fitted with the Guggenheim-Katayama correlation with two or four adjustable parameters. Recommended correlations are proposed for each ester, providing mean absolute deviations below 0.50 mN/m for 77 of them, mean absolute percentage deviations below 1.7% for 76 of them, and percentage deviations below 10%, except for four data out of the 59 selected for tricaprylin. The highest deviations found are due to the disagreement between the data obtained from different sources and not to an inadequate math. form of the correlation model. These correlations are added to the collection of those previously proposed for different fluids, including common substances, alcs., refrigerants, organic acids, n-alkanes, and 80 other esters. (c) 2022 American Institute of Physics. The experimental process involved the reaction of Tris(2-ethylhexyl) benzene-1,2,4-tricarboxylate(cas: 3319-31-1).Quality Control of Tris(2-ethylhexyl) benzene-1,2,4-tricarboxylate

The Article related to aromatic polyfunctional glyceride ester surface tension correlation, Surface Chemistry and Colloids: Liquid-Gas Systems and other aspects.Quality Control of Tris(2-ethylhexyl) benzene-1,2,4-tricarboxylate

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Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

On May 31, 2017, Arslan, Gulsin; Yilmaz, Abdurrahman; Tor, Ali; Ersoz, Mustafa published an article.Formula: C33H54O6 The title of the article was Preparation of polymer inclusion membrane with sodium diethyldithiocarbamate as a carrier reagent for selective transport of zinc ions. And the article contained the following:

This study reports the design of a new type of polymer inclusion membrane (PIM) for selective transport of zinc ion. Sodium diethyldithiocarbamate (NaDDTC) was incorporated in the cellulose acetate-based membrane as a carrier for Zn(II) ion. The PIMs were characterized using Fourier transform IR spectroscopy, SEM, at. force microscopy and contact angle measurements. The effects of parameters, including concentration of Zn(II) in the feed phase, HCl in the stripping phase and amount of NaDDTC incorporated in the membrane, on the transport of Zn(II) ion were studied. For 1×10-4 M of Zn(II) ion in the feed phase at pH 5.04, 96% of Zn(II) ion was transported through the PIMs prepared with 1.0 (wt%) diethyldithiocarbamate via 0.5 M HCl as a stripping phase. The diffusion of Zn(II) ions through the membrane was governed by complex formation between Zn(II) ion and NaDDTC in the membrane. Moreover, selective transport of Zn(II) ion was achieved in the presence of divalent metal ions involving Cu(II), Pb(II) and Ni(II). The prepared PIM provided reproducible transport efficiency, and it can be efficiently used in separation processes. The experimental process involved the reaction of Tris(2-ethylhexyl) benzene-1,2,4-tricarboxylate(cas: 3319-31-1).Formula: C33H54O6

The Article related to polymer inclusion membrane reproducible transport sodium diethyldithiocarbamate zinc ion, Plastics Fabrication and Uses: Plastic Product Uses and other aspects.Formula: C33H54O6

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Ester – an overview | ScienceDirect Topics

Jenke, Dennis; Liu, Norman published an article in 2016, the title of the article was Chromatographic considerations in the standardization of liquid chromatographic methods used for extractables screening.Formula: C33H54O6 And the article contains the following content:

Organic extractables and leachables (E&L) from drug product packaging, manufacturing components, and delivery devices are of concern as they could impact product quality and/or user safety. Proper E&L assessment involves chromatog. profiling of a drug product or extraction solvent, including liquid chromatog. with UV absorption and mass spectrometric detection (LC/UV/MS), to uncover these substances and establish their identities and concentrations Relative retention time (RRT) could be used as one parameter for identifying E&L and relative response factors (RRFs) could be used for quantifying extractables if (a) RRT and RRFs were consistent across various LC/UV/MS methods and instrument systems used for profiling and (b) a database existed for RRT and RRFs. This manuscript addresses (a) by examining the variation in RRT and RRF for model extractables across variations to a specified LC/UV/MS method. Creating and populating a database of relative retention and response data (b) is beyond the manuscript’s scope. Studies which examined small, and more controlled, variations to the method and larger, and less controlled, variations were performed. These assessments support the conclusions that if the operational parameters of the LC/UV/MS are specified and if only relatively minor deviations from these parameters are allowed, then RRTs are sufficiently reproducible that they are an effective means of securing tentative extractable’s identities and UV RRFs are sufficiently reproducible that they provide accurate extractable’s concentrations MS RRFs are less reproducible and only estimate concentration The experimental process involved the reaction of Tris(2-ethylhexyl) benzene-1,2,4-tricarboxylate(cas: 3319-31-1).Formula: C33H54O6

The Article related to organic extractable screening liquid chromatog, Pharmaceutical Analysis: Synthetic Organic Compounds and other aspects.Formula: C33H54O6

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Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

On October 29, 2019, Trivedi, Meeta; Peng, Fang; Xia, Xuhui; Sepulveda-Medina, Pablo I.; Vogt, Bryan D. published an article.Application of 3319-31-1 The title of the article was Control of pore size in ordered mesoporous carbon-silica by Hansen solubility parameters of swelling agent. And the article contained the following:

The cooperative assembly of functional precursors with block copolymers (BCPs) is a powerful, general route to fabricate ordered mesoporous materials, but the precise tuning of the mesopore size generally requires trial and error to obtain the correct BCP template or appropriate swelling agent. Here, we demonstrate the ability to effectively modulate both expansion and contraction of the ordered cylindrical mesopores relative to those obtained from cooperatively assembled Pluronic F127, resol, and tetraethylorthosilicate. The two key phys. parameters for the swelling agents are their hydrophobicity, as quantified by the octanol-water partition coefficient (Kow), and Hansen solubility parameters that describe the interactions of the solvent with the different components of the BCP template. Four low volatility solvents are examined that span a wide Kow with up to 90 wt % solvent relative to the Pluronic F127. Glycerol triacetate (Kow < 1) can decrease the average mesopore size from 5.9 to 4.8 nm due to segmental screening of the interactions in the Pluronic F127 to decrease chain stretching at intermediate loadings. A modest increase in mesopore size to 8.1 nm can be achieved with trimethylbenzene (TMB, Kow = 3.42). Dioctyl phthalate (DOP), which is slightly more hydrophobic (Kow = 8.1), is more effective than TMB at expanding the pore size (maximum: 13.5 nm) without loss of ordered structure. A more hydrophobic solvent, tris (2-ethylhexyl) trimellitate (Kow = 12.5), is less effective at increasing the pore size (maximum: 8.2 nm). The Hansen solubility parameters for DOP most closely match those of the hydrophobic segment in the Pluronic F217 template. We attribute this similarity, which is related to the solvent quality, to the improved efficacy of DOP in increasing the pore size. These results illustrate that both the Hansen solubility parameters (relative to the hydrophobic segment of the template) and relative hydrophobicity of the swelling agent determine the obtainable pore sizes in cooperatively assembled ordered mesoporous materials. The experimental process involved the reaction of Tris(2-ethylhexyl) benzene-1,2,4-tricarboxylate(cas: 3319-31-1).Application of 3319-31-1

The Article related to pore size mesoporous carbon silica hansen solubility swelling agent, Surface Chemistry and Colloids: Solid-Liquid Systems and other aspects.Application of 3319-31-1

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Ester – Wikipedia,
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On January 1, 2017, Bernard, L.; Bourdeaux, D.; Pereira, B.; Azaroual, N.; Barthelemy, C.; Breysse, C.; Chennell, P.; Cueff, R.; Dine, T.; Eljezi, T.; Feutry, F.; Genay, S.; Kambia, N.; Lecoeur, M.; Masse, M.; Odou, P.; Radaniel, T.; Simon, N.; Vaccher, C.; Verlhac, C.; Yessad, M.; Decaudin, B.; Sautou, V. published an article.Name: Tris(2-ethylhexyl) benzene-1,2,4-tricarboxylate The title of the article was Analysis of plasticizers in PVC medical devices: Performance comparison of eight analytical methods. And the article contained the following:

A wide variety of medical devices (MDs) used in hospitals are made of flexible plasticized polyvinylchloride (PVC). Different plasticizers are present in variable amounts in the PVC matrix of the devices and can leach out into the infused solutions and may enter into contact with the patients. The ARMED1ARMED: Assessment and Risk Management of Medical Devices in Plasticized Polyvinylchloride. project aims to assess the migration of these plasticizers from medical devices and therefore the level of exposure in patients. For the first task of the project, eight methods were developed to directly detect and quantify the plasticizers in the PVC matrix of the MDs. We compared the overall performances of the anal. methods using standardized and validated criteria in order to provide the scientific community with the guidance and the tech. specifications of each method for the intended application. We have shown that routine rapid screening could be performed directly on the MDs using the FTIR technique, with cost-effective analyses. LC techniques may also be used, but with limits and only with individual quantification of the main plasticizers expected in the PVC matrix. GC techniques, especially GC-MS, are both more specific and more sensitive than other techniques. NMR is a robust and specific technique to precisely discriminate all plasticizers in a MD but is limited by its cost and its low ability to detect and quantify plasticizer contamination, e.g. by DEHP. All these results have been confirmed by a real test, called the ” blind test ” carried out on 10 MD samples. The experimental process involved the reaction of Tris(2-ethylhexyl) benzene-1,2,4-tricarboxylate(cas: 3319-31-1).Name: Tris(2-ethylhexyl) benzene-1,2,4-tricarboxylate

The Article related to plasticizer polyvinyl chloride medical device analysis method, analytical methods, comparison, medical devices, plasticizers, Pharmaceutical Analysis: Synthetic Organic Compounds and other aspects.Name: Tris(2-ethylhexyl) benzene-1,2,4-tricarboxylate

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

On January 25, 2016, Bourdeaux, Daniel; Yessaad, Mouloud; Chennell, Philip; Larbre, Virginie; Eljezi, Teuta; Bernard, Lise; Sautou, Valerie published an article.Safety of Tris(2-ethylhexyl) benzene-1,2,4-tricarboxylate The title of the article was Analysis of PVC plasticizers in medical devices and infused solutions by GC-MS. And the article contained the following:

In 2008, di-(2-ethylhexyl) phthalate (DEHP), was categorized as CMR 1B under the CLP regulations and its use in PVC medical devices (MD) was called into question by the European authorities. This resulted in the commercialization of PVC MDs plasticized with the DEHP alternative plasticizers tri-octyl trimellitate (TOTM), di-(2-ethylhexyl) terephthalate (DEHT), di-isononyl cyclohexane-1,2-dicarboxylate (DINCH), di-isononyl phthalate (DINP), di-(2-ethylhexy) adipate (DEHA), and Acetyl tri-Bu citrate (ATBC). The data available on the migration of these plasticizers from the MDs are too limited to ensure their safe use. We therefore developed a versatile GC-MS method to identify and quantify both these newly used plasticizers and DEHP in MDs and to assess their migration abilities in simulant solution The use of cubic calibration curves and the optimization of the anal. method by an exptl. plan allowed us to lower the limit of plasticizer quantification. It also allowed wide calibration curves to be established that were adapted to this quantification in MDs during migration tests, irresp. of the amount present, and while maintaining good precision and accuracy. We then tested the developed method on 32 PVC MDs used in our hospital and evaluated the plasticizer release from a PVC MD into a simulant solution during a 24 h migration test. The results showed a predominance of TOTM in PVC MDs accompanied by DEHP (<0.1% weight/weight), DEHT, and sometimes DEHA. The migration tests showed a difference in the migration ability between the plasticizers and a non-linear kinetic release. The experimental process involved the reaction of Tris(2-ethylhexyl) benzene-1,2,4-tricarboxylate(cas: 3319-31-1).Safety of Tris(2-ethylhexyl) benzene-1,2,4-tricarboxylate

The Article related to polyvinyl chloride plasticizer medical device migration, dehp alternatives, gc–ms, medical devices, migration tests, plasticizers, polyvinyl chloride, Pharmaceutical Analysis: Synthetic Organic Compounds and other aspects.Safety of Tris(2-ethylhexyl) benzene-1,2,4-tricarboxylate

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

On September 30, 2018, Hoellerer, Christine; Becker, Guenther; Goeen, Thomas; Eckert, Elisabeth published an article.SDS of cas: 3319-31-1 The title of the article was Human metabolism and kinetics of tri-(2-ethylhexyl) trimellitate (TEHTM) after oral administration. And the article contained the following:

Tri-(2-ethylhexyl) trimellitate (TEHTM) is a plasticizer for PVC material and is used for medical devices as an alternative to di-(2-ethylhexyl) phthalate. As plasticizers are known to migrate easily into contact liquids, exposure of patients to TEHTM is highly probable. In the present study, human metabolism pathways of TEHTM and its elimination kinetics were investigated. For that purpose, four healthy volunteers were orally exposed to a single dose of TEHTM. TEHTM and its postulated primary metabolites were investigated in blood samples (up to 48 h after exposure), and in urine samples (collected until 72 h after exposure) using liquid chromatog. tandem mass spectrometry (LC-MS/MS). TEHTM was found to be regioselectively hydrolyzed to its diesters di-2-(ethylhexyl) trimellitates (1,2-DEHTM, 2,4-DEHTM) with maximum blood concentrations at 3-h post-exposure, and to its monoester isomers mono-2-(ethylhexyl) trimellitates (1-MEHTM, 2-MEHTM) with peak blood concentrations 5-h post-exposure. For the elimination of investigated urinary metabolites, biphasic elimination kinetics was observed The most dominant urinary biomarker was found to be 2-MEHTM (2-mono-(2-ethylhexyl) trimellitate), followed by several specific secondary metabolites. All in all, approx. 5.8% of the orally administered dose was recovered in urine over a period of 72 h, indicating a comparatively low resorption rate of TEHTM in humans in combination with an apparently rather slow metabolism and excretion rate. In fact, TEHTM and selected metabolites were still detectable in blood and urine 48-h and 72-h post-exposure, resp. This study is the first to elucidate TEHTM metabolism pathways in humans and to identify metabolites of TEHTM in blood and urine by usage of especially designed human biomonitoring methods. Powerful tools for exposure monitoring and risk assessment of TEHTM are therewith available for future research. The experimental process involved the reaction of Tris(2-ethylhexyl) benzene-1,2,4-tricarboxylate(cas: 3319-31-1).SDS of cas: 3319-31-1

The Article related to metabolism kinetics tehtm, biomonitoring, elimination kinetics, human metabolism, plasticizers, tri-(2-ethylhexyl) trimellitate, Toxicology: Chemicals (Household, Industrial, General) and other aspects.SDS of cas: 3319-31-1

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

On January 31, 2016, Fromme, H.; Schuetze, A.; Lahrz, T.; Kraft, M.; Fembacher, L.; Siewering, S.; Burkardt, R.; Dietrich, S.; Koch, H. M.; Voelkel, W. published an article.HPLC of Formula: 3319-31-1 The title of the article was Non-phthalate plasticizers in German daycare centers and human biomonitoring of DINCH metabolites in children attending the centers (LUPE 3). And the article contained the following:

Plasticizers have been widely used for decades as additives in diverse applications, including consumer and building products, toys, cables, and floorings. Due to toxicol. concerns and restrictions of different dialkyl ortho-phthalates, other plasticizers have been increasingly used in recent years. Therefore, di-isononyl cyclohexane-1,2-dicarboxylate (DINCH), di(2-ethylhexyl) terephthalate (DEHT), di(2-ethylhexyl) adipate (DEHA), acetyl tri-Bu citrate (ATBC), and trioctyl trimellitate (TOTM) plasticizer levels in indoor air and dust samples from 63 daycare centers in Germany were measured. Moreover, the urine samples of 208 children who attend 27 of these facilities were analyzed for the presence of four DINCH metabolites.DINCH, DEHT, and DEHA were present in indoor air with median values of 108 ng/m3, 20 ng/m3, and 34 ng/m3, resp. Median values of 302 mg/kg for DINCH, 49 mg/kg for DEHA, 40 mg/kg for DEHT, and 24 mg/kg ATBC were found in dust. In the urine samples, the three secondary metabolites of DINCH were observed with median values (95th percentiles) of 1.7 μg/l (10.0 μg/l) for OH-MINCH, 1.5 μg/l (8.0 μg/l) for oxo-MINCH, and 1.1 μg/l (6.1 μg/l) for cx-MINCH. Overall, these metabolite levels are orders of magnitude lower than the current HBM I values set by the German Human Biomonitoring Commission.Using general exposure assumptions, the intake resulting from dust ingestion and inhalation is low for children. The total daily DINCH intake calculated from biomonitoring data was 0.5 μg/kg b.w. using median values and 9.8 μg/kg b.w. as the maximum value. At present, non-phthalate plasticizers, especially DINCH, can be found in considerable amounts in dust samples from daycare centers and as DINCH metabolites in the urine of children. In relation to previous studies, the concentrations of DINCH in dust and urine have an increasing time trend. Compared with tolerable daily intake values, the total daily intake of DINCH reached only 1% of its maximum value to date; however, due to its increased use, higher exposure of DINCH is expected in the future. The experimental process involved the reaction of Tris(2-ethylhexyl) benzene-1,2,4-tricarboxylate(cas: 3319-31-1).HPLC of Formula: 3319-31-1

The Article related to nonphthalate plasticizer dinch urine germany, deha, deht, dinch, daycare centers, human biomonitoring, indoor air, plasticizer, Toxicology: Chemicals (Household, Industrial, General) and other aspects.HPLC of Formula: 3319-31-1

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Ester – an overview | ScienceDirect Topics

McCombie, Gregor; Biedermann, Sandra; Suter, Gaby; Biedermann, Maurus published an article in 2017, the title of the article was Survey on plasticizers currently found in PVC toys on the Swiss market: Banned phthalates are only a minor concern.Quality Control of Tris(2-ethylhexyl) benzene-1,2,4-tricarboxylate And the article contains the following content:

Plasticizers in toys are a recurring source of criticism and concern, as consumers feel they may endanger the health of their children. Most of the information available in literature concerns the presence or absence of certain phthalic acid ester plasticizers. Very little information can be found in the public domain with respect to the actually used plasticizers at a given time and place. In this paper, we present the plasticizer composition of 118 samples from 88 polyvinyl chloride toys found on the Swiss market in autumn 2015. Bis(2-ethylhexyl) terephthalate (DEHT) was by far the most frequent main plasticizer in the analyzed samples, which is a change when compared to the plasticizers found in toys and child care articles in 2007. Furthermore, the data show that the banned phthalates in toys are only a minor concern. The occurrence, however, is not evenly distributed between importers. If a toy is not designed to be sold on the European market by the manufacturer, it seems to be more likely to contain a banned phthalic acid ester. The experimental process involved the reaction of Tris(2-ethylhexyl) benzene-1,2,4-tricarboxylate(cas: 3319-31-1).Quality Control of Tris(2-ethylhexyl) benzene-1,2,4-tricarboxylate

The Article related to plasticizer phthalate polyvinyl chloride switzerland, dehp, pvc, phthalates, plasticizers, toy safety, Toxicology: Chemicals (Household, Industrial, General) and other aspects.Quality Control of Tris(2-ethylhexyl) benzene-1,2,4-tricarboxylate

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

On March 31, 2018, Hoellerer, Christine; Becker, Guenther; Goeen, Thomas; Eckert, Elisabeth published an article.Electric Literature of 3319-31-1 The title of the article was Regioselective ester cleavage of di-(2-ethylhexyl) trimellitates by porcine liver esterase. And the article contained the following:

In a comparative study the ester hydrolysis of the plasticizers di-(2-ethylhexyl) phthalate (DEHP) and tri-(2-ethylhexyl) trimellitate (TEHTM) as well as of the diester isomers 1,2-di-(2-ethylhexyl) trimellitate (1,2-DEHTM), 1,4-di-(2-ethylhexyl) trimellitate (1,4-DEHTM) and 2,4-di-(2-ethylhexyl) trimellitate (2,4-DEHTM) was investigated by a newly developed in vitro exptl. using porcine liver esterase (PLE). The substrates were incubated with PLE for 48 h at 25° in borate buffer and samples were taken at predetermined intervals during the experiment The samples were processed using liquid-liquid extraction and analyzed using LC-MS/MS. The results demonstrated a rapid and extensive hydrolysis of the diester DEHP to the monoester mono-(2-ethylhexyl) phthalate (MEHP) during the incubation with PLE. The isomers of DEHTM were also hydrolyzed by PLE to a high extent, whereas TEHTM showed a high stability against enzymic hydrolysis. The regioselective anal. revealed that the monoester isomers 1-MEHTM and 2-MEHTM were predominantly produced during the degradation of DEHTM isomers, indicating a preferred hydrolysis at the para-position. These findings are eminent for planning further investigations on the human TEHTM metabolism, as the extent, rate and route of metabolism are of crucial importance for a toxicol. assessment. The experimental process involved the reaction of Tris(2-ethylhexyl) benzene-1,2,4-tricarboxylate(cas: 3319-31-1).Electric Literature of 3319-31-1

The Article related to pig liver esterase dehp tehtm dehtm, di-(2-ethylhexyl) phthalate, metabolism, porcine liver esterase, tri-(2-ethylhexyl) trimellitate, Toxicology: Chemicals (Household, Industrial, General) and other aspects.Electric Literature of 3319-31-1

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Ester – an overview | ScienceDirect Topics