Category: 3290-92-4

Fan, Pei-Ru; Zhao, Xue; Wei, Ze-Hui; Huang, Yan-Ping; Liu, Zhao-Sheng published the artcile< Robust immobilized enzyme reactor based on trimethylolpropane trimethacrylate organic monolithic matrix through ""thiol-ene"" click reaction>, Application In Synthesis of 3290-92-4, the main research area is immobilized enzyme reactor trimethylolpropane trimethacrylate organic monolithic matrix.

A novel immobilized enzyme reactor (IMER) based on trimethylolpropane trimethacrylate (TRIM) organic monolith was prepared by “”thiol-ene”” click reaction. The IMERs were made by fabricating TRIM monolith core in advance. There were residual double bonds on the surface of TRIM monolith, in which click reaction can be performed with the free thiol groups of trypsin at room temperature to bond the trypsin on the monolithic column without addnl. introducing an active functional group. The enzyme activity was characterized by kinetic parameters Km and Vmax and determined by off-line chromatog. The performance of the IMERs was evaluated by digesting standard protein BSA and compared with in-solution digestion method. By using IMER 5 min, the sequence coverage rate of BSA was 79.41%, which was similar to that in-solution digestion for 12 h (82.7%). The applicability of the IMERs in complex samples was assessed by digesting crude protein extracts from egg white and mouse liver, identifying 28 (104 peptides) and 843 (3916 peptides) proteins, resp. All results indicated that the IMERs have great potential in high-throughput proteomics anal.

European Polymer Journal published new progress about Bioreactors. 3290-92-4 belongs to class esters-buliding-blocks, and the molecular formula is C18H26O6, Application In Synthesis of 3290-92-4.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Fu, Yunxing; Zhang, Dezhong; Zhan, Hongmei; Zhao, Chenyang; Cheng, Yanxiang; Qin, Chuanjiang; Wang, Lixiang published the artcile< Engineering of Annealing and Surface Passivation toward Efficient and Stable Quasi-2D Perovskite Light-Emitting Diodes>, COA of Formula: C18H26O6, the main research area is perovskite light emitting diode annealing surface passivation.

Solution-processed quasi-two-dimensional (quasi-2D) perovskites with self-assembled multiple quantum well (QW) structures exhibit enhanced exciton binding energy, which is ideal for use as light emitters. Here, we have found that postannealing is important to promoting the QWs’ composition transfer, and we explored the correlation among the annealing time, the external quantum efficiency (EQE), and the operational stability of the device. During thermal annealing, the low-n QWs will gradually convert to high-n phases, accompanied by an increase in grain size. The EQE and working stability of the device exhibit different annealing-time dependences; i.e., with the extension of the annealing time, the EQE gradually decreases while the working stability improves. By introducing trimethylolpropane trimethacrylate (TPTA) to passivate the emitting-region defects, the annealing-time dependence of the EQE was effectively eliminated due to the reduction of the nonradiative recombination rate, wherefore high efficiency and stability can be achieved simultaneously. Our research provides an effective way to develop highly efficiency and stable perovskite light-emitting diodes.

Journal of Physical Chemistry Letters published new progress about Annealing. 3290-92-4 belongs to class esters-buliding-blocks, and the molecular formula is C18H26O6, COA of Formula: C18H26O6.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Liu, Jin; Cai, Xuhong; Liu, Junbo; Liang, Dadong; Chen, Kaiyin; Tang, Shanshan; Xu, Bao published the artcile< Study on the Preparation of Estrone Molecularly Imprinted Polymers and Their Application in a Quartz Crystal Microbalance Sensor via a Computer-Assisted Design>, Synthetic Route of 3290-92-4, the main research area is estrone estriol MIPs itaconic acid quartz crystal microbalance sensor; computational design; estrone; molecularly imprinted polymers; quartz crystal microbalance; selectivity.

Computer simulations are widely used for the selection of conditions for the synthesis of molecularly imprinted polymers and can rapidly reduce the exptl. cycle time and save labor and materials. In this paper, estrone molecularly imprinted polymers (E1-MIPs) are designed at the M062X/6-311+G(d,p) level with itaconic acid (IA) as the functional monomer. The imprinted molar ratio between E1 and IA was optimized, cross-linkers and solvents were screened, and the nature of interactions between E1 and IA was explored. The simulated results showed that pentaerythritol triacrylate was the best cross-linker. Meanwhile, when the imprinted molar ratio between E1 and IA was 1:4, the E1-IA complex had the largest amount of hydrogen bonds, the lowest binding energy, and the strongest stability. Using the simulation results as guidance, the E1-MIPs were prepared to modify the electrons of a quartz crystal microbalance (QCM) sensor. The exptl. studies showed that the E1-MIPs-QCM sensor had the highest adsorption capacity to E1 in comparison with their analogs, and the lowest detection value of the sensor was 16.00 μg/L. The computer simulations and exptl. studies could provide guidance for synthesize novel E1-MIPs materials. It also could provide important references and directions for the application of E1-MIPs.

International Journal of Molecular Sciences published new progress about Adsorption. 3290-92-4 belongs to class esters-buliding-blocks, and the molecular formula is C18H26O6, Synthetic Route of 3290-92-4.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Manaila, Elena; Craciun, Gabriela; Ighigeanu, Daniel; Lungu, Ion Bogdan; Dumitru, Marius; Stelescu, Maria Daniela published the artcile< Electron beam irradiation: a method for degradation of composites based on natural rubber and plasticized starch>, Recommanded Product: 2-Ethyl-2-((methacryloyloxy)methyl)propane-1,3-diyl bis(2-methylacrylate), the main research area is natural rubber plasticized starch composite electron beam irradiation degradation; phys structural morphol mech property; degradation; electron beam; filler; natural rubber; plasticized starch.

Polymeric composites based on natural rubber (NR) and plasticized starch (PS) obtained by peroxide crosslinking have been subjected to electron beam irradiation in order to investigate their degradation The amount of PS ranged from 10 to 50 phr and the irradiation dose from 150 to 450 kGy. Irradiation was performed in atm. conditions using a linear electron accelerator of 5.5 MeV. Changes in chem., phys., structural, and morphol. properties of composites were correlated with variables, such as PS loading and irradiation dose. Thus, mech. properties, gel fraction, crosslinking degree, water uptake, weight loss in toluene/water were compared with those obtained before irradiation The changes in structure and morphol. were studied by Fourier transform IR spectroscopy and SEM. Both PS loading and irradiation dose were found to be responsible for the degradation installing. Moreover, it has been shown that at the dose of 450 kGy, chain scission is dominant over crosslinking.

Polymers (Basel, Switzerland) published new progress about Absorption (water). 3290-92-4 belongs to class esters-buliding-blocks, and the molecular formula is C18H26O6, Recommanded Product: 2-Ethyl-2-((methacryloyloxy)methyl)propane-1,3-diyl bis(2-methylacrylate).

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Tsuboi, Ririko; Kitagawa, Haruaki; Imazato, Satoshi published the artcile< FGF-2 release and bonding/physical properties of 4-META/MMA-based adhesive resins incorporating small FGF-2-loaded polymer particles>, Formula: C18H26O6, the main research area is adhesive resin incorporating small FGF loaded polymer particle; Adhesive resin; FGF-2; Mechanical property; Osteoblast-like cell; polyHEMA/TMPT.

Non-biodegradable particles comprising hydroxyethyl methacrylate (HEMA) and trimethylolpropane trimethacrylate (TMPT) have been reported as useful carriers for fibroblast growth factor-2 (FGF-2). They have also been successfully incorporated into the 4-[2-(methacryloyloxy)ethoxycarbonyl]phthalic anhydride/methyl methacrylate-tri-Bu borane (4-META/MMA-TBB) resin to promote tissue regeneration. However, smaller particles are required to obtain restorative materials acceptable for clin. use. The aim of this study was to investigate the ability of the 4-META/MMA-TBB resin that comprises small FGF-2-loaded particles to release FGF-2 and promote cell proliferation. In addition, the bonding and phys. properties of the exptl. resin were evaluated.The small particles loaded with FGF-2 were newly fabricated and incorporated into the com. 4-META/MMA-TBB resin. Release profiles of FGF-2 from the exptl. resins were assessed, and the cell proliferation cultured with the eluate was evaluated. The bonding and phys. properties of the resins were evaluated using shear bond strength and three-point bending tests, and by measuring the curing time, water absorption, and water dissolutionSustained release of FGF-2 from the exptl. resins for two weeks was observed, and the released FGF-2 was demonstrated to promote cell proliferation. All bonding and phys. properties of the 4-META/MMA-TBB resins were found acceptable for clin. use.The small FGF-2-loaded particles incorporated into the 4-META/MMA-TBB resin had the same abilities to release FGF-2 and proliferate cells, as those exhibited by the conventionally sized particles. In addition, there were no adverse influences on bonding and phys. properties, suggesting that the bioactive adhesive resin was acceptable for clin. use.

Dental Materials published new progress about Absorption. 3290-92-4 belongs to class esters-buliding-blocks, and the molecular formula is C18H26O6, Formula: C18H26O6.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Betlem, K.; Mahmood, I.; Seixas, R. D.; Sadiki, I.; Raimbault, R. L. D.; Foster, C. W.; Crapnell, R. D.; Tedesco, S.; Banks, C. E.; Gruber, J.; Peeters, M. published the artcile< Evaluating the temperature dependence of heat-transfer based detection: A case study with caffeine and Molecularly Imprinted Polymers as synthetic receptors>, Application of C18H26O6, the main research area is molecularly imprinted polymer heat transfer method caffeine environmental contamination.

Molecularly Imprinted Polymers (MIPs) are synthesized for the selective detection of caffeine. The polymerization process, monomer and crosslinker monomer composition are varied to determine the optimal synthesis procedure via batch rebinding experiments evaluated with optical detection. The selectivity is tested by comparing the response of caffeine to compounds with similar chem. structures (theophylline and theobromine) and dopamine, another neurotransmitter. Subsequently, the MIP polymer particles are integrated into bulk modified MIP screen-printed electrodes (MIP-modified SPEs). The sensors are used to measure caffeine content in various samples employing the Heat-Transfer Method (HTM), a low-cost and simple thermal detection method that is based on differences in thermal resistance at the solid-liquid interface. At first, the noise is minimized by adjusting the settings of temperature feedback loop. Second, the response of the MIP-modified SPE is studied at various temperatures ranging from 37 to 50 and 85 °C. The binding to MIP-modified SPEs has never been studied at elevated temperatures since most biomols. are not stable at those temperatures Using caffeine as proof-of-concept, it is demonstrated that at 85 °C the detection limit is significantly enhanced due to higher signal to noise ratios and enhanced diffusion of the biomol. Thermal wave transport anal. (TWTA) is also optimized at 85 °C producing a limit of detection of ∼1 nM. Next, MIP-modified SPEs are used to measure the caffeine concentration in complex samples including caffeinated beverages, spiked tap water and waste water samples. The use of MIP-modified SPEs combined with thermal detection provides sensors that can be used for fast and low-cost detection performed on-site, which holds great potential for the determination of contaminants in environmental samples. The platform is generic and by adapting the MIP layer, we can expand to this a range of relevant targets.

Chemical Engineering Journal (Amsterdam, Netherlands) published new progress about Drinking waters. 3290-92-4 belongs to class esters-buliding-blocks, and the molecular formula is C18H26O6, Application of C18H26O6.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Chen, Zhiliang; Liu, Xiaojie; Huang, Chuixiu; Li, Jilai; Shen, Xiantao published the artcile< Artificial Cytochrome c Mimics: Graphene Oxide-Fe(III) Complex-Coated Molecularly Imprinted Colloidosomes for Selective Photoreduction of Highly Toxic Pollutants>, SDS of cas: 3290-92-4, the main research area is artificial cytochrome mimic GO iron complex MIP colloidosome pollutant; Pickering emulsion; cytochrome c mimics; graphene oxide−Fe(III) complex; molecularly imprinted polymers; non-heme enzyme; photocatalytic reduction.

Our previous works showed that the molecularly imprinted TiO2 photocatalyst has been one of the most efficient materials for selective photooxidation of highly toxic organic pollutants (HTOPs) from complicated wastewater. However, some highly toxic pollutants (e.g., heavy metals) are very stable under the oxidizing environment. Therefore, the design of enzyme-like catalysts to selectively reduce highly toxic pollutants is extremely needed. In this work, inspired by the bioreduction ability of cytochrome c (cyt c, a heme containing metalloprotein), we presented a simple and efficient way to generate an artificial cyt c mimic (ACM) using graphene oxide (GO)-Fe(III) complex-coated molecularly imprinted colloidosomes. Prior to loading of Fe(III) centers to GO for constructing ACMs, GO-coated molecularly imprinted colloidosomes were synthesized via Pickering emulsion polymerization Similar to a nature cyt c, the ACM contained both the mol. recognition element (molecularly imprinted cavity) and the non-heme electron sink (GO-Fe(III) complex), which resulted in the ACMs having good selectivity toward the enzyme-like reduction of the highly toxic target Cr(VI). Moreover, by using HepG2 cells as model cells, the Cr(VI) solution after treating by ACMs was proved to be safe and nontoxic. To confirm that the present method was universal for constructing ACMs, various GO-Fe(III) complex-coated molecularly imprinted colloidosomes, which could selectively photoreduce other highly toxic inorganic ions and organic pollutants, were also investigated. The ACMs described herein will act as a vector that encourages the design of more functional non-heme enzymes in sensing, environmental separation, clin. diagnose, and delivery of therapeutic agents.

ACS Applied Materials & Interfaces published new progress about Mammalian cell. 3290-92-4 belongs to class esters-buliding-blocks, and the molecular formula is C18H26O6, SDS of cas: 3290-92-4.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Hong, Sihui; She, Yongxin; Cao, Xiaolin; Wang, Miao; He, Yahui; Zheng, Lufei; Wang, Shanshan; Abd El-Aty, A. M.; Hacimuftuoglu, Ahmet; Yan, Mengmeng; Wang, Jing published the artcile< A novel CdSe/ZnS quantum dots fluorescence assay based on molecularly imprinted sensitive membranes for determination of triazophos residues in cabbage and apple>, Reference of 3290-92-4, the main research area is cadmium selenium zinc sulfide quantumdot fluorescence triazofos sensitive membrane; CdSe/ZnS QDs probe; cabbage and apple; fluorescence assay; imprinted array film; triazophos.

In the present study we have developed a direct competitive CdSe/ZnS quantum dot (QD) fluorescence assay based on micro-array-imprinted membranes for the determination of triazophos in cabbage and apple. The imprinted membranes were directly synthesized on the surface of a 96-well plate by thermal polymerization using triadimefon as the dummy template. Under optimal conditions, the assay showed an excellent linear response over the concentration ranges of 0.1-10,000μg L-1 with a good coefficient of determination (R2= 0.982). The sensitivity (IC50) and limit of detection (LOD, expressed as IC15) of the developed assay were 3.63 mg L-1 and 0.31μg L-1, resp. The applicability of the developed approach was tested for detecting triazophos in incurred samples. The method showed excellent recoveries (109.6-118.9%) and relative standard deviations (RSDs) between 9.9 and 19.5%. The obtained results correlated well with those obtained by LC-MS/MS (R2= 0.9995). The competitive assay using CdSe/ZnS QDs as fluorescence-labeled probe showed good sensitivity, steady and fast response, and excellent anti-interference ability compared to conventional fluorescence-quenching methods. Finally, the feasibility of the proposed methodol. was successfully applied for detection of triazophos in real samples.

Frontiers in Chemistry (Lausanne, Switzerland) published new progress about Apple. 3290-92-4 belongs to class esters-buliding-blocks, and the molecular formula is C18H26O6, Reference of 3290-92-4.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Liang, Xianyu; Liu, Fan; Wan, Yiqun; Yin, Xiaoying; Liu, Weiting published the artcile< Facile synthesis of molecularly imprinted polymers for selective extraction of tyrosine metabolites in human urine>, Electric Literature of 3290-92-4, the main research area is molecularly imprinted polymer tyrosine metabolite extraction urine; Human urine; Molecular imprinted polymer; Selective extraction; Tyrosine metabolites; Ultra-high performance liquid chromatography.

In this study a method is developed for quant. anal. of three potential biomarkers, including 4-hydroxyphenyl acetic acid (PHPAA), 4-hydroxyphenyl lactic acid (PHPLA) and 3,4-hydroxyphenylpropionic acid (PHPA), in human urine. Mol. imprinted polymers (MIPs) as the sample clean up materials were applied to selectively extract these tyrosine metabolites, followed by precise detection using ultra-high performance liquid chromatog. coupled with a fluorescence detector (UHPLC-FLD). The MIP was prepared by precipitation polymerization adopting PHPAA as the template mol., 1-vinylimidazole (1-vinyl) as functional monomer, trimethylolpropane triacrylate (TRIM) as crosslinker, 2-methylpropionitrile (AIBN) as initiator and acetonitrile as a porogen. The mol. recognition properties and selectivity of MIPs were systematically evaluated, of which results demonstrated high selectivity for three analytes in human urine. Parameters affecting the extraction efficiency were further optimized. Under the optimum conditions, the limits of detection of PHPAA, PHPLA, and PHPA were 1.8 × 10-4, 4.7 × 10-5 and 5.8 × 10-5 mmol L-1, resp., and the recoveries were in the range of 75.7%-110.3%. The method described here provided insights into the future development of materials for highly efficient and selective enrichment of targeted substances.

Journal of Chromatography A published new progress about Homo sapiens. 3290-92-4 belongs to class esters-buliding-blocks, and the molecular formula is C18H26O6, Electric Literature of 3290-92-4.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

He, Yahui; Zeng, Shaomei; Abd El-Aty, A. M.; Hacimuftuoglu, Ahmet; Yohannes, Woldemariam Kalekristos; Khan, Majid; She, Yongxin published the artcile< Development of water-compatible molecularly imprinted polymers based on functionalized β-cyclodextrin for controlled release of atropine>, Product Details of C18H26O6, the main research area is atropine beta cyclodextrin water compatible molecularly imprinted polymer; Atropine; controlled release; molecularly imprinted polymers; water-compatible; β-cyclodextrin.

Herein, a novel method for molecularly imprinted polymers (MIPs) using methacrylic acid functionalized beta-cyclodextrin (MAA-β-CD) monomer is presented, which was designed as a potential water-compatible composite for the controlled release of atropine (ATP). The molecularly imprinted microspheres with pH-sensitive characteristics were fabricated using thermally-initiated precipitation polymerization, employing ATP as a template mol. The effects of different compounds and concentrations of crosslinking agents were systematically investigated. Uniform microspheres were obtained when the ratio between ATP, MAA-β-CD, and trimethylolpropane trimethacrylate (TRIM) was 1:4:20 (mol/mol/mol) in polymerization system. The ATP loading equilibrium data was best suited to the Freundlich and Langmuir isotherm models. The in vitro drug release study was assessed under simulated oral administration conditions (pH 1.5 and 7.4). The potential usefulness of MIPs as drug delivery devices are much better than non-molecularly imprinted polymers (NIPs). The study shows that the prepared polymers are a pH stimuli-responsive system, which controlled the release of ATP, indicating the potential applications in the field of drug delivery.

Polymers (Basel, Switzerland) published new progress about Drug delivery systems. 3290-92-4 belongs to class esters-buliding-blocks, and the molecular formula is C18H26O6, Product Details of C18H26O6.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics