Category: 3290-92-4

Wang, Zhichao; Cheng, Huiyan; Qi, Lingli; Sui, Dayun published the artcile< Comprehensive analysis of long non-coding RNA using an associated competitive endogenous RNA network in Wilms tumor>, HPLC of Formula: 3290-92-4, the main research area is gene expression mir135a 3p mir125b 5p prognosis Wilms tumor; Wilms tumor; competitive endogenous rna; long non-coding rna; Therapeutically applicable research to Generate effective Treatments database; prognosis.

Wilms tumor (WT) is the most common malignant renal neoplasm in children; however, the underlying mol. mechanisms are not well understood. The expression profiles of lncRNAs, miRNAs and mRNAs in 120 WT and six normal tissues were obtained from the Therapeutically Applicable Research to Generate Effective Treatments database. A total of 442 lncRNAs, 214 miRNAs and 4,912 mRNAs were identified as differentially expressed in WT and were enriched in 472 Gene Ontol. terms (355 biol. processes, 89 cellular components and 29 mol. functions) and 18 Kyoto Encyclopedia of Genes and Genomes pathways. A lncRNA-miRNA-mRNA ceRNA network of WT consisting of with 32 lncRNAs, 14 miRNAs and 158 mRNAs was constructed, based on the bioinformatics anal. of the miR target prediction database and the miRNAcode, miRTarBase and TargetScan databases. Subsequently, three lncRNAs, three miRNAs and 17 mRNAs, which had a significant effect on the overall survival rate of patients with WT, were identified based on the survival anal. The three lncRNAs were also differentially expressed in the late and early stages of WT and were validated using the GSE66405 dataset obtained from the Gene Expression Omnibus database. In conclusion, the present study generated a specific lncRNA-related ceRNA network of WT, which may provide a novel perspective on the mol. mechanisms underlying the progression and prognosis of the disease.

Molecular Medicine Reports published new progress about Cell aging. 3290-92-4 belongs to class esters-buliding-blocks, and the molecular formula is C18H26O6, HPLC of Formula: 3290-92-4.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Foroozan, Ali; Behboodi, Tahereh; Jahani, Yousef published the artcile< Influence of branching on the rheology and morphology of melt state long-chain branched polypropylene/polybuten-1 blends>, Related Products of 3290-92-4, the main research area is polybutene polypropylene blend branching viscosity.

In this study, the compatibility of polypropylene (PP)/polybutene-1 (PB-1) homopolymer blends before and after a long-chain branching process was studied. The blends were prepared and long-chain branched directly via a reactive extrusion process in the presence of a free radical initiator and trimethylolpropane trimethacrylate (TMPTMA) poly functional monomer. The optimum percentage of TMPTMA and PB-1 resin was determined by measuring the grafting efficiency and by studying the rheol. behavior in steady state shear and transient extensional mode and the morphol. of samples was investigated by SEM. The morphol. observations, which were also approved by rheol. data, demonstrated an enhanced compatibility for the blend branched with 1.5wt% of TMPTMA and 10wt% of PB-1 resin. The highest grafting efficiency of 37% and branch index of 5.2 were achieved for this blend composition The zero-shear viscosity (η0) of PP increased from 4500 Pa.s to 6800 Pa.s after branching process, and further enhanced to 2400 Pa.s by using 10 wt% PB-1 resin. The long-chain branched structure of blend resulted in a prominent higher zero-shear viscosity, a longer relaxation time and a pronounced strain-hardening behaviors. The branch index of blend samples were determined, and their branching behavior was quantified using extensional viscosity data.

Polyolefins Journal published new progress about Branched polymer chains. 3290-92-4 belongs to class esters-buliding-blocks, and the molecular formula is C18H26O6, Related Products of 3290-92-4.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Zhang, Hui; Shang, Yan; Zhao, Hong; Wang, Xuan; Han, Baozhong; Li, Zesheng published the artcile< Further discussion on the reaction behaviour of triallyl isocyanurate in the UV radiation cross-linking process of polyethylene: a theoretical study>, Application of C18H26O6, the main research area is triallyl isocyanurate polyethylene crosslinking UV radiation; UV radiation cross-linking polyethylene process; transition states; triallyl isocyanurate.

Further theor. investigation on the reaction behavior of triallyl isocyanurate (TAIC) in the UV radiation crosslinking process of polyethylene (PE) is accomplished by d. functional theory for high voltage cable insulation materials. The reaction potential energy information of the 13 reaction channels at B3LYP/6-311 + G(d,p) level are identified. These have been explored that the TAIC take part in the reaction behavior on ground state during UV radiation crosslinking process and TAIC intra-mol. isomerization reaction itself. In addition, the results show that the effect of multiplication and acceleration for the crosslinking reaction of trimethylolpropane trimethacrylate(TMPTMA) would be better than that of TAIC. It has further clarified the reasons why UV radiation crosslinking reaction of PE had been initiated by benzophenone (Bp), and the TAIC or TMPTMA needed to take part. The results obtained in the present study could directly guide both the optimization of UV radiation crosslinking PE process and the development of the insulation material of high-voltage cable in real application.

Royal Society Open Science published new progress about Band gap. 3290-92-4 belongs to class esters-buliding-blocks, and the molecular formula is C18H26O6, Application of C18H26O6.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Nunez-Briones, A. G.; Benavides, R.; Mendoza-Mendoza, E.; Martinez-Pardo, M. E.; Carrasco-Abrego, H.; Kotzian, C.; Saucedo-Zendejo, F. R.; Garcia-Cerda, L. A. published the artcile< Preparation of PVC/Bi2O3 composites and their evaluation as low energy X-Ray radiation shielding>, Formula: C18H26O6, the main research area is polyvinyl chloride bismuth oxide composite radiation shielding.

Plasticized and gamma crosslinked PVC composites were prepared by adding different amounts of Bi2O3 particles to evaluate their low energy X-ray radiation shielding properties. Composites were gamma-irradiated in an industrial irradiator (60Co source) at the corresponding times to obtain a dose of 75 kGy to enhance mech. properties through crosslinking. The shielding properties of composites were obtained by X-ray transmission measurements at low energies (X-ray tube voltages range 20-61 kV) by using a mammog. unit and an X-ray hospital equipment. A small influence in the dehydroclorination reaction of PVC was observed during decomposition in TGA experiments due to Bi2O3 nanoparticle content, but DMA results show improved viscoelastic properties for the crosslinked composites. The X-ray transmission values decrease as a function of nanoparticle content, observing an increase in the transmission values (low attenuation) at higher energies. The composite with 50wt.% of Bi2O3 showed the lowest transmission values, at X-ray tube voltages 20-30 kV, the transmittance was almost nil, and then it increases ∼27% at 61 kV.

Radiation Physics and Chemistry published new progress about Complex modulus, tan δ. 3290-92-4 belongs to class esters-buliding-blocks, and the molecular formula is C18H26O6, Formula: C18H26O6.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Lei, Xiaoyun; Cui, Jiaxing; Wang, Shuqiang; Huang, Ting; Wu, Xiaoping published the artcile< Preparation of a biomimetic ionic liquids hybrid polyphosphorylcholine monolithic column for the high efficient capillary microextraction of glycopeptide antibiotics>, COA of Formula: C18H26O6, the main research area is capillary microextraction glycopeptide antibiotics; Biomimetic enrichment; Capillary microextraction; Glycopeptide antibiotics; Ionic liquids; Phosphorylcholine.

An ionic liquid hybrid zwitterionic polymer capillary microextraction (CME) column was prepared for the biomimetic enrichment of glycopeptides by one-step copolymerization of 2-methacryloyloxyethyl phosphorylcholine (MPC) and 1-butyl-3-vinylimidazolium bromide, in the presence of crosslinker trimethylolpropane trimethacrylate (TMA). The resultant monolith was characterized by SEM (SEM), fourier transform IR (FT-IR) spectroscopy and pore size distribution measurement. Due to the incorporation of zwitterionic MPC owning a unique biomimic structure (i.e. hydrophilic cation/anion and hydrophobic long-alkyl chain), the monolithic column has large pore size and good biocompatibility, exhibiting high extraction efficiency, permeability and fast mass transfer to targets. Besides, the use of ionic liquids (ILs) as co-monomer in the polymerization endows the monolith with enhanced mech. stability, uniformity and multiple interactions. The prepared column was successfully applied in CME coupled to capillary electrochromatog. (CEC) for the efficient enrichment and separation of glycopeptide antibiotics in foodstuff. The method demonstrated a wide linear range (50.0-18000.0μg L-1), low detection limits (5.0-10.0μg L-1, S/N = 3) and satisfied recoveries (76.0-109.7%). This work shows the advantage of fine-tuning biomimetic monoliths in application-specific CME-CEC.

Journal of Chromatography A published new progress about Antibiotics. 3290-92-4 belongs to class esters-buliding-blocks, and the molecular formula is C18H26O6, COA of Formula: C18H26O6.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Kierys, Agnieszka; Zaleski, Radoslaw; Grochowicz, Marta; Gorgol, Marek; Sienkiewicz, Andrzej published the artcile< Polymer-mesoporous silica composites for drug release systems>, Application In Synthesis of 3290-92-4, the main research area is polymer mesoporous silica composite drug.

The research describes systematic approach to the novel synthesis and formation of a potential organic-inorganic drug carriers. The poly(trimethylolpropane trimethacrylate) and polymer-silica composites based on SBA-3 or SBA-15 mesoporous silica were fabricated by the suspension-emulsion polymerization method in the form of small micrometric porous beads (sp. surface area approx. 500 m2/g). The type of organic templates filling silica pores has proved to be crucial in the synthesis of the composites. The introduction of diclofenac sodium via solvent diffusion method into the polymer and composites resulted in the solid drug dispersions. The composites have greater effectiveness in the drug desorption (90% of the release) in comparison with the pure polymer (20% of the release after 7 h). Both, however, suffer from the burst effect. This downside can be overcome by functionalization of the solid drug dispersions with (3-aminopropyl)triethoxysilane. The functionalized solid drug dispersions do not desorb the diclofenac sodium in an acidic medium (the desorption rate is less than 6% during 2 h contact), which makes them attractive for oral multiparticulate formulations of modified release. The presented solids were characterized with modern anal. methods and the relation between the material structure and desorption rate were discussed.

Microporous and Mesoporous Materials published new progress about Composites. 3290-92-4 belongs to class esters-buliding-blocks, and the molecular formula is C18H26O6, Application In Synthesis of 3290-92-4.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Montagna, Valentina; Haupt, Karsten; Gonzato, Carlo published the artcile< RAFT coupling chemistry: a general approach for post-functionalizing molecularly imprinted polymers synthesized by radical polymerization>, Recommanded Product: 2-Ethyl-2-((methacryloyloxy)methyl)propane-1,3-diyl bis(2-methylacrylate), the main research area is RAFT coupling chem imprinted polymer radical polymerization.

Molecularly imprinted polymers (MIPs) are well-known as antibody mimics, with binding properties for their target on a par with those of biomacromols. such as antibodies or enzymes. A great majority of MIPs is nowadays synthesized by free-radical polymerization (FRP), owing to the mild reaction conditions, tolerance for monomer and solvent impurities and high flexibility in terms of polymerization setups. Nevertheless, FRP MIPs lack suitable functionalities for a further elaboration of their structures via, for instance, extension with consecutive blocks. This results in practical limitations for FRP imprinted scaffolds in terms of adapting them to a given application. In this work, we show that FRP MIPs can easily be functionalized with “”living”” moieties for chain extension, by coupling a chain transfer (RAFT) agent to the ubiquitous unreacted double bonds on the MIP surface. Imprinted nanoparticles synthesized by precipitation polymerization, as well as microparticles obtained by bulk polymerization and mech. milling, were reacted with a dithioester or a trithiocarbonate in the presence of a radical source. This resulted in RAFT coupling which allowed the surface grafting of polymer brushes, while the imprinted scaffolds retained their binding properties in terms of template affinity and selectivity. Upon extension with poly(N-isopropylacrylamide) p(NIPAm), RAFT-coupled MIPs also acquired excellent binding properties in aqueous media, compared to unmodified particles which just exhibited non-specific binding. Thus, this easy approach, which takes advantage of a common feature of crosslinked particles obtained by FRP, is expected to be of general interest due to the easy post-modification and fine-tuning of the material’s surface properties.

Polymer Chemistry published new progress about Dithiocarboxylic acids, esters Role: PAC (Pharmacological Activity), BIOL (Biological Study). 3290-92-4 belongs to class esters-buliding-blocks, and the molecular formula is C18H26O6, Recommanded Product: 2-Ethyl-2-((methacryloyloxy)methyl)propane-1,3-diyl bis(2-methylacrylate).

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Alamgir, Md.; Nayak, G. C.; Mallick, Ashis; Sahoo, Sumanta published the artcile< Effects of TiO2 and GO nanoparticles on the thermomechanical properties of bioactive poly-HEMA nanocomposites>, Computed Properties of 3290-92-4, the main research area is HEMA titanium dioxide graphene oxide nanoparticle thermomech property.

Abstract: Bioactive polymeric nanocomposites are indispensable materials and have received great attention owing to their diverse applications in human body. In this study, a poly(hydroxyethyl methacrylate) (pHEMA) complex was prepared using hydroxyethyl methacrylate (HEMA) as a base material and trimethylolpropane trimethacrylate (TMPTA) and benzoyl peroxide (BPO) as crosslinking agents. The pHEMA nanocomposites were prepared by melt processing technique. In this process, a twin screw extruder machine was used. Twin screw extrusion is used extensively for mixing, compounding, or reacting polymeric materials. The flexibility of twin screw extrusion equipment allows this operation to be designed specifically for the formulation being processed. The nanocomposites of pHEMA/TiO2 and pHEMA/TiO2/GO were synthesized using pHEMA as a matrix with the addition of a small amounts of titanium oxide nanoparticles (TiO2 1 wt) and graphene oxide (GO 0.1 wt) as reinforcement materials. The thermomech. study of pHEMA/TiO2 and pHEMA/TiO2/GO nanocomposites was carried out via thermogravimetric (TGA), differential scanning calorimetry (DSC), micro-indentation, micro-scratch, and FTIR analyses, and compression testing. The microstructural characterization of the nanocomposites was studied by FESEM and XRD anal. Significant changes in microstructural behavior with improved thermomech. properties were observed in pHEMA/TiO2 and pHEMA/TiO2/GO nanocomposites as compared to pure pHEMA. In this work, pure pHEMA and pHEMA/TiO2 and pHEMA/TiO2/GO nanocomposites were studied for dental applications.

Iranian Polymer Journal published new progress about Nanocomposites. 3290-92-4 belongs to class esters-buliding-blocks, and the molecular formula is C18H26O6, Computed Properties of 3290-92-4.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Chen, Yung-Chung; Liu, Ting-Yu; Li, Yan-Heng published the artcile< Photoreactivity study of photoinitiated free radical polymerization using Type II photoinitiator containing thioxanthone initiator as a hydrogen acceptor and various amine-type co-initiators as hydrogen donors>, Electric Literature of 3290-92-4, the main research area is TMPTMA photopolymerization thioxanthone initiator hydrogen acceptor donor.

In this work, free radical photopolymerization of trimethylolpropane trimethacrylate (TMPTMA) is initiated. We investigated the corresponding photoreactivity by using Type II photoinitiator (PI) systems based on thioxanthone (TX) as a hydrogen acceptor and five amine-type mols., such as N-phenylglycine (NPG), triethylamine (TEA), triethanolamine (TEOA), 2,2′-(4-methylphenylimino)diethanol (p-TDEA), and N-phenyldiethanolamine (n-PDEA), as hydrogen donors. Their photochem. and photophys. properties are studied. The TX hydrogen acceptor displayed rather red-shifted compared to all the hydrogen donor compounds The hydrogen donor compounds exhibited the absorption band at lower than 300 nm, which followed the trend of p-TDEA > n-PDEA > NPG > TEOA > TEA. All the packages exhibit good electron-transfer ability by the calculation of the free energy changes (ΔGET) through cyclic voltammetry (CV) measurement. However, the hydrogen donors with different steric hindrance, secondary, and tertiary amines have a decisive influence on the photoreactivity; i.e., the TX/TEOA package shows the best double-bond conversion (DC) efficiency than other formulations under similar weight ratios (hydrogen acceptor: hydrogen donor = 1:2 wt%). We then conduct the photoreactivity based on TX/TEOA formulation with different weight ratios. The DC values are in the order of 1:2 wt% > 1.5:1.5 wt% > 2:1 wt%. Under suitable amount of hydrogen donor, the TX/TEOA-based formulation also exhibits stable DC value at air atm.

Journal of Coatings Technology and Research published new progress about Electric current-potential relationship. 3290-92-4 belongs to class esters-buliding-blocks, and the molecular formula is C18H26O6, Electric Literature of 3290-92-4.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Zahara, Sonia; Minhas, Muhammad Ali; Shaikh, Huma; Ali, Muhammad Shaiq; Bhanger, Muhammad Iqbal; Malik, Muhammad Imran published the artcile< Molecular imprinting-based extraction of rosmarinic acid from Salvia hypoleuca extract>, Electric Literature of 3290-92-4, the main research area is salvia hypoleuca rosmarinic acid extraction mol imprinting.

This study presents selective and efficient extraction of a medicinally important compound rosmarinic acid (RA) via mol. imprinting. Molecularly imprinted polymer (MIP) and its resp. non-imprinted polymer (NIP) were synthesized using methacrylamide (MAAm), itaconic acid (IA), and 4-vinyl-1,3-dioxolan-2-one (VD) as functional monomers, and trimethylolpropane trimethacrylate (TRIM) as a crosslinker via bulk polymerization, and characterized by SEM, BET, FT-IR, and TGA. The adsorption properties of MIP were evaluated by batch rebinding experiments, Scatchard anal., LF-isotherm, and kinetic models. The MIP showed higher adsorption capacity towards RA compared to the corresponding NIP: 41.9 mg/g compared to only 9.6 mg/g. In addition, the synthesized RA-MIP displayed a good selectivity towards RA compared to its structural analogs in competitive recognition studies, confirming the development of RA specific imprinting sites. HPLC was utilized to determine the concentration of RA and analogous compounds in competitive recognition tests and in the real sample anal. Finally, RA-MIP was successfully utilized for the selective enrichment of RA from the ethanolic extract of Salvia hypoleuca. The obtained results show that RA-MIP can be a promising alternative to conventional extraction methods for the selective extraction and enrichment of RA from complex plant matrixes.

Reactive & Functional Polymers published new progress about Adsorption. 3290-92-4 belongs to class esters-buliding-blocks, and the molecular formula is C18H26O6, Electric Literature of 3290-92-4.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics