Category: 329-59-9

In 2010,Chandrappa, S.; Vinaya, K.; Ramakrishnappa, T.; Rangappa, K. S. published 《An efficient method for aryl nitro reduction and cleavage of azo compounds using iron powder/calcium chlorideã€?Synlett published the findings.HPLC of Formula: 329-59-9 The information in the text is summarized as follows:

A novel, efficient Fe/CaCl2 system was revealed for the reduction of nitro-arenes and reductive cleavage of azo compounds by catalytic transfer hydrogenation. The selective reduction of nitro compounds in the presence of sensitive functional groups including halides, carbonyl, hydroxyl, aldehyde, Me, methoxy, acetyl, nitrile, and ester substituents with an excellent yields is reported. The simple exptl. procedure and easy purification make the protocol advantageous. In the experiment, the researchers used Methyl 4-fluoro-3-nitrobenzoate(cas: 329-59-9HPLC of Formula: 329-59-9)

Methyl 4-fluoro-3-nitrobenzoate(cas: 329-59-9) belongs to methyl benzoate. Methyl benzoate reacts at both the ring and the ester, depending on the substrate. Electrophiles attack the ring, illustrated by acid-catalysed nitration with nitric acid to give methyl 3-nitrobenzoate.HPLC of Formula: 329-59-9

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

In 2015,Yoon, Y. K.; Ali, M. A.; Wei, A. C.; Choon, T. S.; Oon, C. E.; Shirazi, A. N.; Parang, K. published 《Discovery of a potent and highly fluorescent sirtuin inhibitor [Erratum to document cited in CA163:681200]》.MedChemComm published the findings.Application In Synthesis of Methyl 4-fluoro-3-nitrobenzoate The information in the text is summarized as follows:

C.E. Oon was omitted from the author list on page 1857; the corrected author and affiliation lists are given. The experimental process involved the reaction of Methyl 4-fluoro-3-nitrobenzoate(cas: 329-59-9Application In Synthesis of Methyl 4-fluoro-3-nitrobenzoate)

Methyl 4-fluoro-3-nitrobenzoate(cas: 329-59-9) belongs to methyl benzoate. Methyl benzoate reacts at both the ring and the ester, depending on the substrate. Electrophiles attack the ring, illustrated by acid-catalysed nitration with nitric acid to give methyl 3-nitrobenzoate.Application In Synthesis of Methyl 4-fluoro-3-nitrobenzoateMethyl 4-fluoro-3-nitrobenzoate is used to prepare dimethyl 3-nitro-3′,4-oxydibenzoate by reacting with 3-hydroxy-benzoic acid methyl ester.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

The author of 《Substituent effects on the isomerization of hydrazone switches driven by the intramolecular hydrogen bond》 were Lu, Chaocao; Bu, Htan; Fu, Shitao; Ma, Chunmiao; Gan, Quan. And the article was published in Tetrahedron in 2019. Category: esters-buliding-blocks The author mentioned the following in the article:

In this work, the substituent effects on hydrogen bonding in one kind of hydrazone-based switch are revealed. The E/Z isomerization ratios of these hydrazones and their intramol. hydrogen bond strengths in the Z form were evaluated using NMR technique. Linear correlations between these parameters and Hammett empirical values for substituent effects are explored as well. After reading the article, we found that the author used Methyl 4-fluoro-3-nitrobenzoate(cas: 329-59-9Category: esters-buliding-blocks)

Methyl 4-fluoro-3-nitrobenzoate(cas: 329-59-9) belongs to methyl benzoate. Methyl benzoate reacts at both the ring and the ester, depending on the substrate. Electrophiles attack the ring, illustrated by acid-catalysed nitration with nitric acid to give methyl 3-nitrobenzoate.Category: esters-buliding-blocksMethyl 4-fluoro-3-nitrobenzoate is used to prepare dimethyl 3-nitro-3′,4-oxydibenzoate by reacting with 3-hydroxy-benzoic acid methyl ester.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Quality Control of Methyl 4-fluoro-3-nitrobenzoateIn 2018 ,《Metal-Free Synthesis of Pyrrolo[1,2-a]quinoxalines Mediated by TEMPO Oxoammonium Salts》 appeared in Synthesis. The author of the article were Huo, Heng-rui; Tang, Xiang-Ying; Gong, Yue-fa. The article conveys some information:

We herein describe a novel TEMPO oxoammonium salt initiated Pictet-Spengler reaction of imines, generated in situ from carbonyl compounds and pyrrole- or indole-containing substrates, to afford 4,5-dihydropyrrolo[1,2- a]quinoxalines or 5,6-dihydroindolo[1,2- a]quinoxalines in good to excellent yields. Moreover, a one-pot synthesis of a biol. important quinoxaline is achieved via a cyclization-dehydrogenation process using one equivalent of the oxoammonium salt. The experimental process involved the reaction of Methyl 4-fluoro-3-nitrobenzoate(cas: 329-59-9Quality Control of Methyl 4-fluoro-3-nitrobenzoate)

Methyl 4-fluoro-3-nitrobenzoate(cas: 329-59-9) belongs to methyl benzoate. Methyl benzoate reacts at both the ring and the ester, depending on the substrate. Electrophiles attack the ring, illustrated by acid-catalysed nitration with nitric acid to give methyl 3-nitrobenzoate.Quality Control of Methyl 4-fluoro-3-nitrobenzoate

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

In 2008,Portilla, Jaime; Quiroga, Jairo; Abonia, Rodrigo; Insuasty, Braulio; Nogueras, Manuel; Cobo, Justo; Mata, Ernesto G. published 《Solution-phase and solid-phase synthesis of 1-pyrazol-3-ylbenzimidazoles》.Synthesis published the findings.Safety of Methyl 4-fluoro-3-nitrobenzoate The information in the text is summarized as follows:

The facile solution and solid-phase synthesis of 1-pyrazol-3-ylbenzimidazoles, e.g., I, from 4-fluoro-3-nitrobenzoate derivatives and 5(3)-amino-3(5)-substituted-1H-pyrazoles is reported. The key step is the unexpected nucleophilic aromatic displacement of the activated fluorine by the exocyclic amino group of the pyrazole ring leading to 4-pyrazolylamino-3-nitrobenzoate derivatives, which are easily converted into the corresponding 1-pyrazol-3-ylbenzimidazoles in very high isolated yield. These novel methodologies would be very useful for the generation of libraries of diverse 1-heteroaryl derivatives of benzimidazoles.Methyl 4-fluoro-3-nitrobenzoate(cas: 329-59-9Safety of Methyl 4-fluoro-3-nitrobenzoate) was used in this study.

Methyl 4-fluoro-3-nitrobenzoate(cas: 329-59-9) belongs to methyl benzoate. Methyl benzoate reacts at both the ring and the ester, depending on the substrate. Electrophiles attack the ring, illustrated by acid-catalysed nitration with nitric acid to give methyl 3-nitrobenzoate.Safety of Methyl 4-fluoro-3-nitrobenzoateMethyl 4-fluoro-3-nitrobenzoate is used to prepare dimethyl 3-nitro-3′,4-oxydibenzoate by reacting with 3-hydroxy-benzoic acid methyl ester.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

In 2008,Snape, Timothy J. published 《α-Arylation of aryl ketones: expanding the scope of the Truce-Smiles rearrangement》.Synlett published the findings.Reference of Methyl 4-fluoro-3-nitrobenzoate The information in the text is summarized as follows:

The Truce-Smiles rearrangement was applied to the synthesis of substituted α-aryl aryl ketones and the synthetic utility of the products was demonstrated by the conversion of one of them to 2-(1H-indol-2-yl)phenol. In addition to this study using Methyl 4-fluoro-3-nitrobenzoate, there are many other studies that have used Methyl 4-fluoro-3-nitrobenzoate(cas: 329-59-9Reference of Methyl 4-fluoro-3-nitrobenzoate) was used in this study.

Methyl 4-fluoro-3-nitrobenzoate(cas: 329-59-9) belongs to methyl benzoate. Methyl benzoate reacts at both the ring and the ester, depending on the substrate. Electrophiles attack the ring, illustrated by acid-catalysed nitration with nitric acid to give methyl 3-nitrobenzoate.Reference of Methyl 4-fluoro-3-nitrobenzoateMethyl 4-fluoro-3-nitrobenzoate is used to prepare dimethyl 3-nitro-3′,4-oxydibenzoate by reacting with 3-hydroxy-benzoic acid methyl ester.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Gao, Qian; Lu, Jia-Ming; Yao, Lingyun; Wang, Siqi; Ying, Jun; Wu, Xiao-Feng published an article in 2021. The article was titled 《Cobalt-catalyzed direct C-H carbonylative synthesis of free (NH)-indolo[1,2-a]quinoxalin-6(5H)-ones》, and you may find the article in Organic Letters.Application of 329-59-9 The information in the text is summarized as follows:

A cobalt-catalyzed direct C-H carbonylative reaction of N-(2-(1H-indol-1-yl)phenyl)picolinamides for the synthesis of (NH)-indolo[1,2-a]quinoxalin-6(5H)-one skeletons has been developed. Using benzene-1,3,5-triyl triformate (TFBen) as the CO source and picolinamide as the traceless directing group, various free (NH)-indolo[1,2-a]quinoxalin-6(5H)-ones were obtained in good yields (up to 88%). Addnl., a series of product derivatizations were demonstrated, and the core fragment of PARP-1 inhibitor C can be readily constructed by this protocol. The results came from multiple reactions, including the reaction of Methyl 4-fluoro-3-nitrobenzoate(cas: 329-59-9Application of 329-59-9)

Methyl 4-fluoro-3-nitrobenzoate(cas: 329-59-9) belongs to methyl benzoate. Methyl benzoate reacts at both the ring and the ester, depending on the substrate. Electrophiles attack the ring, illustrated by acid-catalysed nitration with nitric acid to give methyl 3-nitrobenzoate.Application of 329-59-9

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Dong, Yaxi; Breit, Bernhard published their research in Organic Letters in 2021. The article was titled 《Cu-Catalyzed C-H Allylation of Benzimidazoles with Allenes》.SDS of cas: 329-59-9 The article contains the following contents:

CuH-catalyzed intramol. cyclization and intermol. allylation of benzimidazoles with allenes have been described. The reaction proceeded smoothly with the catalytic system of Cu(OAc)2/Xantphos and catalytic amount of (MeO)2MeSiH. This protocol features mild reaction conditions and a good tolerance of substrates bearing electron-withdrawing, electron-donating, or electron-neutral groups. A new catalytic mechanism was proposed for this copper hydride catalytic system. In addition to this study using Methyl 4-fluoro-3-nitrobenzoate, there are many other studies that have used Methyl 4-fluoro-3-nitrobenzoate(cas: 329-59-9SDS of cas: 329-59-9) was used in this study.

Methyl 4-fluoro-3-nitrobenzoate(cas: 329-59-9) belongs to methyl benzoate. Methyl benzoate reacts at both the ring and the ester, depending on the substrate. Electrophiles attack the ring, illustrated by acid-catalysed nitration with nitric acid to give methyl 3-nitrobenzoate.SDS of cas: 329-59-9Methyl 4-fluoro-3-nitrobenzoate is used to prepare dimethyl 3-nitro-3′,4-oxydibenzoate by reacting with 3-hydroxy-benzoic acid methyl ester.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Yang, Shuo; An, Xiao-De; Qiu, Bin; Liu, Rui-Bin; Xiao, Jian published an article in 2021. The article was titled 《Access to Polycyclic Indole-3,4-fused Nine-membered Ring via Cascade 1,6-Hydride Transfer/Cyclizations》, and you may find the article in Organic Letters.Recommanded Product: 329-59-9 The information in the text is summarized as follows:

A cascade aldimine condensation/1,6-hydride transfer/Mannich-type cyclization of indole-derived phenylenediamine with aldehydes was developed for one-step construction of polycyclic indole 3,4-fused skeleton I [R = Ph, 3-MeC6H4, 4-MeOC6H4, etc.; R1 = H, 9-Cl, 10-Me, etc.; R2 = H, 4-Ph]. Aldehyde served as a key to start the whole process, including 1,6-hydride transfer enabled β-C(sp3)-H activation of the secondary amine. The challenges of construction of medium-sized rings were addressed via hydride transfer chem. After reading the article, we found that the author used Methyl 4-fluoro-3-nitrobenzoate(cas: 329-59-9Recommanded Product: 329-59-9)

Methyl 4-fluoro-3-nitrobenzoate(cas: 329-59-9) belongs to methyl benzoate. Methyl benzoate reacts at both the ring and the ester, depending on the substrate. Electrophiles attack the ring, illustrated by acid-catalysed nitration with nitric acid to give methyl 3-nitrobenzoate.Recommanded Product: 329-59-9Methyl 4-fluoro-3-nitrobenzoate is used to prepare dimethyl 3-nitro-3′,4-oxydibenzoate by reacting with 3-hydroxy-benzoic acid methyl ester.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

In 2019,Organic Letters included an article by Guo, Lirong; Liu, Fengting; Wang, Liying; Yuan, Hairui; Feng, Lei; Kurti, Laszlo; Gao, Hongyin. Reference of Methyl 4-fluoro-3-nitrobenzoate. The article was titled 《Cascade Approach to Highly Functionalized Biaryls by a Nucleophilic Aromatic Substitution with Arylhydroxylamines》. The information in the text is summarized as follows:

A transition-metal free synthesis of highly functionalized 2-hydroxy-2′-amino-1,1′-biaryls from N-arylhydroxylamines has been developed. This operationally simple and readily scalable approach relies on a cascade of reactions that initially generates transient N,O-diarylhydroxylamines, via direct O-arylation, which then undergo rapid [3,3]-sigmatropic rearrangement and subsequent rearomatization to form NOBIN-type products, e.g., I. These structurally diverse functionalized biaryls are obtained under mild conditions in good to excellent isolated yields. The experimental part of the paper was very detailed, including the reaction process of Methyl 4-fluoro-3-nitrobenzoate(cas: 329-59-9Reference of Methyl 4-fluoro-3-nitrobenzoate)

Methyl 4-fluoro-3-nitrobenzoate(cas: 329-59-9) belongs to methyl benzoate. Methyl benzoate reacts at both the ring and the ester, depending on the substrate. Electrophiles attack the ring, illustrated by acid-catalysed nitration with nitric acid to give methyl 3-nitrobenzoate.Reference of Methyl 4-fluoro-3-nitrobenzoateMethyl 4-fluoro-3-nitrobenzoate is used to prepare dimethyl 3-nitro-3′,4-oxydibenzoate by reacting with 3-hydroxy-benzoic acid methyl ester.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics