Nakai, Diogo K. et al. published their research in Journal of Chromatography A in 2022 | CAS: 31566-31-1

Glyceryl monostearate (cas: 31566-31-1) belongs to esters. Esters perform as high-grade solvents for a broad array of plastics, plasticizers, resins, and lacquers, and are one of the largest classes of synthetic lubricants on the commercial market. Cyclic esters are called lactones, regardless of whether they are derived from an organic or inorganic acid. One example of an organic lactone is γ-valerolactone.SDS of cas: 31566-31-1

Evaporative light scattering detection based reversed-phase ultra-high-performance liquid chromatography method to quantify intermediates and end products of biodiesel production was written by Nakai, Diogo K.;Ribeiro, Jose A. A.;Martins, Pedro A.;Soares, Itania P.;Salum, Thais F. C.;Costa, Patricia P. K. G.. And the article was included in Journal of Chromatography A in 2022.SDS of cas: 31566-31-1 The following contents are mentioned in the article:

A fast method based on reversed-phase ultra-high-performance liquid chromatog. using evaporative light scattering detection (RP-UHPLC-ELSD) was developed for monitoring the intermediates and end products of biodiesel production Gradient elution of water, acetonitrile, and a mixture of acetonitrile:2-propanol:n-hexane was used. With a minimal and easy sample preparation, fatty acid Me esters (FAME), fatty acid Et esters (FAEE), free fatty acids (FFA), monoacylglycerols (MAG), diacylglycerols (DAG), and triacylglycerols (TAG) were successfully separated The developed method was used to monitor an ethylic enzymic transesterification of soybean oil and to characterize the ester content of Me and Et biodiesel. The ester content obtained was compared with the reference method by gas chromatog. and flame ionization detector (GC-FID), with similar results for both Me and Et biodiesel. The presented method is a simple and fast alternative, a 17 min run, to monitor the transesterification process, simultaneously quantifying all the analytes produced in the reaction: biodiesel and its intermediates. Limits of detection (LOD, between 29 and 307 ng) and quantification (LOQ, between 48 and 614 ng), linearity (R2>0.99), precision (between 0.30 and 6.58%), and accuracy (between 81.6 and 119.9%) were determined for the twenty-one compounds This study involved multiple reactions and reactants, such as Glyceryl monostearate (cas: 31566-31-1SDS of cas: 31566-31-1).

Glyceryl monostearate (cas: 31566-31-1) belongs to esters. Esters perform as high-grade solvents for a broad array of plastics, plasticizers, resins, and lacquers, and are one of the largest classes of synthetic lubricants on the commercial market. Cyclic esters are called lactones, regardless of whether they are derived from an organic or inorganic acid. One example of an organic lactone is γ-valerolactone.SDS of cas: 31566-31-1

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Li, Jiaxi et al. published their research in LWT–Food Science and Technology in 2021 | CAS: 31566-31-1

Glyceryl monostearate (cas: 31566-31-1) belongs to esters. Esters perform as high-grade solvents for a broad array of plastics, plasticizers, resins, and lacquers, and are one of the largest classes of synthetic lubricants on the commercial market. Polyesters are important plastics, with monomers linked by ester moieties. Cyclic esters are called lactones, regardless of whether they are derived from an organic or inorganic acid. One example of an organic lactone is γ-valerolactone.Recommanded Product: 31566-31-1

Comprehensive evaluation of saturated monoglycerides for the forming of oleogels was written by Li, Jiaxi;Guo, Ruihua;Bi, Yanlan;Zhang, Hong;Xu, Xuebing. And the article was included in LWT–Food Science and Technology in 2021.Recommanded Product: 31566-31-1 The following contents are mentioned in the article:

To investigate the effect of monoglyceride (MGs) acyl chain length and compounding of MGs on the oleogel properties and stability, 3 different pure MGs and 7 mixtures with different glycerol monostearate (MS): glycerol monobehenate (MB) ratios were studied with high oleic sunflower oil (HOSO) as the liquid oil. The oleogel properties were characterized in terms of structuring potential including oil binding capacity (OBC), hardness and rheol. behavior, and the microstructural features associated with these properties determined by differential scanning calorimetry (DSC), solid fat content (SFC), X-ray diffractometry (XRD) and polarized light microscopy (PLM). Changes in oleogel properties (OBC and hardness) and the microstructure during 30 days of storage were also evaluated. Different chain lengths and ratios of MS:MB led to different crystallization rates, polymorphic transitions and aggregation rates, so as to form different crystalline networks and stabilities. In general, the MB oleogel exhibited the highest properties and stability. An increase in OBC in the order of glycerol monolaurate (ML) < MS < MB was observed for pure MG oleogels. The oleogels with mixed MGs outperformed the mech. properties of the single ones. The best oleogel properties and stabilities were obtained for the oleogel with the MS:MB ratio as 2:8. This study involved multiple reactions and reactants, such as Glyceryl monostearate (cas: 31566-31-1Recommanded Product: 31566-31-1).

Glyceryl monostearate (cas: 31566-31-1) belongs to esters. Esters perform as high-grade solvents for a broad array of plastics, plasticizers, resins, and lacquers, and are one of the largest classes of synthetic lubricants on the commercial market. Polyesters are important plastics, with monomers linked by ester moieties. Cyclic esters are called lactones, regardless of whether they are derived from an organic or inorganic acid. One example of an organic lactone is γ-valerolactone.Recommanded Product: 31566-31-1

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Sawale, Sunil Rambhau et al. published their research in World Journal of Pharmaceutical Research in 2022 | CAS: 31566-31-1

Glyceryl monostearate (cas: 31566-31-1) belongs to esters. Esters perform as high-grade solvents for a broad array of plastics, plasticizers, resins, and lacquers, and are one of the largest classes of synthetic lubricants on the commercial market. Cyclic esters are called lactones, regardless of whether they are derived from an organic or inorganic acid. One example of an organic lactone is γ-valerolactone.HPLC of Formula: 31566-31-1

Nanostuctured lipid based drug delivery system of lopinavir- optimization and evaluation was written by Sawale, Sunil Rambhau;Shete, R. V.;Bhagat, Vishwas C.;Deshmukh, Madhuri T.. And the article was included in World Journal of Pharmaceutical Research in 2022.HPLC of Formula: 31566-31-1 The following contents are mentioned in the article:

By using the high-shear homogenization method Nanostructured lipid carriers (NLCs) loaded with lopinavir (LOP) were prepared The LOPNLCs formulations were freeze-dried using POLOXOMER 188 as a cryoprotectant. A burst release is shown by in vitro release studies in simulated gastric fluid (pH 1.2) and simulated intestinal fluid (pH 6.8). The optimized freeze-dried formulation (LOP-NLC) had a particle size (PS), zeta potential (ZP) and % entrapment efficiency (%EE) of 159.5 _ 3.75 nm, 0.413 _ 0.017, -46 mV and 97.77 _ 4.46%, resp. A spherical shape was observed in the optimized formulation by transmission and scanning electron microscopes. The absence of chem. interaction between the drug and lipids is observed in Differential scanning Calorimetry study. In vitro study is performed using the bulk-equilibrium reverse dialysis technique, to investigate LOP release from optimized LOP-NLC and pure drug suspension in different media. The optimized formulations stored in amber glass container were found to be phys. and chem. stable for three months at room temperature The bioavailability of LOP following oral administration of LOP-NLC in male Wistar rats was found 4.52-fold higher than the LOP-suspension. So the conclusion is:- for improving the oral bioavailability of lopinavir, the nanostructure lipid carriers are potential carriers. This study involved multiple reactions and reactants, such as Glyceryl monostearate (cas: 31566-31-1HPLC of Formula: 31566-31-1).

Glyceryl monostearate (cas: 31566-31-1) belongs to esters. Esters perform as high-grade solvents for a broad array of plastics, plasticizers, resins, and lacquers, and are one of the largest classes of synthetic lubricants on the commercial market. Cyclic esters are called lactones, regardless of whether they are derived from an organic or inorganic acid. One example of an organic lactone is γ-valerolactone.HPLC of Formula: 31566-31-1

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Lin, Yunwei et al. published their research in International Journal of Food Science and Technology in 2022 | CAS: 31566-31-1

Glyceryl monostearate (cas: 31566-31-1) belongs to esters. Esters perform as high-grade solvents for a broad array of plastics, plasticizers, resins, and lacquers, and are one of the largest classes of synthetic lubricants on the commercial market. Esterification is the general name for a chemical reaction in which two reactants (typically an alcohol and an acid) form an ester as the reaction product. Esters are common in organic chemistry and biological materials.Name: Glyceryl monostearate

Influence of different solid lipids on the properties of a novel nanostructured lipid carrier containing Antarctic krill oil was written by Lin, Yunwei;Yin, Wenting;Li, Yujie;Liu, Guoqin. And the article was included in International Journal of Food Science and Technology in 2022.Name: Glyceryl monostearate The following contents are mentioned in the article:

This study aimed to investigate the effect of solid lipids (lauric acid (LAU), myristic acid (MYR), stearic acid (STE), glycerol monostearate (GMS), glycerol 1,3-distearate (GDS), glycerol tristearate (GTS), glycerol trimyristate (GTM) and glycerol trilaurate (GTL)) on the characteristics of novel nanostructured lipid carrier (NLC) containing Antarctic krill oil through ultrasound. The fatty acids (LAU, MYR, STE and GMS) were unsuitable solid lipid materials, as apparent stratification was quickly observed during the NLC preparation NLCs were successfully prepared using GTS, GTM, GTL and GDS. The zeta potential of all NLCs exceeded -30 mV indicating good uniformity and stability. These NLCs appeared spherical or oval. Differential calorimetry and X-ray diffraction anal. revealed these NLCs formed imperfect crystals. As the carbon chain length of triglycerides increased from C12 to C18, the particle size of NLCs increased from 235.8 ± 2.3 nm to 340.5 ± 2.2 nm, the degree of recrystallization increased from 39.06% to 49.99%, while the EPA encapsulation efficiency decreased from 88.72 ± 0.47% to 72.86 ± 1.06%. NLC prepared with GDS had the smallest particle size (112.4 ± 0.4 nm), the lowest recrystallization and the highest EPA encapsulation efficiency (>99%). GDS was the most suitable to prepare high encapsulate efficiency krill oil-loaded NLC. This study involved multiple reactions and reactants, such as Glyceryl monostearate (cas: 31566-31-1Name: Glyceryl monostearate).

Glyceryl monostearate (cas: 31566-31-1) belongs to esters. Esters perform as high-grade solvents for a broad array of plastics, plasticizers, resins, and lacquers, and are one of the largest classes of synthetic lubricants on the commercial market. Esterification is the general name for a chemical reaction in which two reactants (typically an alcohol and an acid) form an ester as the reaction product. Esters are common in organic chemistry and biological materials.Name: Glyceryl monostearate

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Chilukuri, Chandraprakash et al. published their research in World Journal of Pharmacy and Pharmaceutical Sciences in 2022 | CAS: 31566-31-1

Glyceryl monostearate (cas: 31566-31-1) belongs to esters. Carboxylic acid esters of low molecular weight are colourless, volatile liquids with pleasant odours, slightly soluble in water. Esters contain a carbonyl center, which gives rise to 120° C–C–O and O–C–O angles. Unlike amides, esters are structurally flexible functional groups because rotation about the C–O–C bonds has a low barrier. Their flexibility and low polarity is manifested in their physical properties; they tend to be less rigid (lower melting point) and more volatile (lower boiling point) than the corresponding amides. SDS of cas: 31566-31-1

Formulation and evaluation of ezetimibe loaded solid lipid nanoparticles was written by Chilukuri, Chandraprakash;Haq, S. Muhammad Fazal Ul. And the article was included in World Journal of Pharmacy and Pharmaceutical Sciences in 2022.SDS of cas: 31566-31-1 The following contents are mentioned in the article:

Ezetimibe is an anti Hyperlipidemic drug with low bioavailability (35%) and poor aqueous solubility (0-00846 mg/L.) The present study was focused to enhance the bioavailability of ezetimibe. Drug loaded solid lipid nanoparticles were prepared by using high shear homogenization and ultrasonication method using glycerol mono sterate as lipid and tween 80, poloxamer 188 as surfactants. Prepared solid lipid nanoparticles were characterized for particle size, surface morphol. and thermal properties. Evaluation studies like entrapment efficiency, Invitro drug release studies, and stability studies. The optimized formulation of ezetimbe loaded solid lipid nanoparticles exhibited particle size (432 nm), zeta potential (-13.8mV) and poly dispersity index (0.168). Thermal property studies performed by using differential scanning calorimetry showed no chem. interaction between drug and lipid. Entrapment efficiency of optimized formulation was found to be 88.72 ± 0.21%. scanning electron microscope study revealed solid lipid nanoparticles were spherical in shape with smooth surface. invitro drug release studies showed a drug release of 89.2 ± 0.2% for optimized formulation. Stability studies performed on the optimized formulation at different temperatures for 2 mo revealed there is slight decrease in the stability of drug loaded solid lipid nanoparticles. This study involved multiple reactions and reactants, such as Glyceryl monostearate (cas: 31566-31-1SDS of cas: 31566-31-1).

Glyceryl monostearate (cas: 31566-31-1) belongs to esters. Carboxylic acid esters of low molecular weight are colourless, volatile liquids with pleasant odours, slightly soluble in water. Esters contain a carbonyl center, which gives rise to 120° C–C–O and O–C–O angles. Unlike amides, esters are structurally flexible functional groups because rotation about the C–O–C bonds has a low barrier. Their flexibility and low polarity is manifested in their physical properties; they tend to be less rigid (lower melting point) and more volatile (lower boiling point) than the corresponding amides. SDS of cas: 31566-31-1

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Krishnan, Nived et al. published their research in World Journal of Pharmaceutical Research in 2022 | CAS: 31566-31-1

Glyceryl monostearate (cas: 31566-31-1) belongs to esters. Carboxylic acid esters of low molecular weight are colourless, volatile liquids with pleasant odours, slightly soluble in water. Many esters have the potential for conformational isomerism, but they tend to adopt an s-cis (or Z) conformation rather than the s-trans (or E) alternative, due to a combination of hyperconjugation and dipole minimization effects. The preference for the Z conformation is influenced by the nature of the substituents and solvent, if present. Lactones with small rings are restricted to the s-trans (i.e. E) conformation due to their cyclic structure.Application In Synthesis of Glyceryl monostearate

Formulation and evalution of herbal vanishing cream was written by Krishnan, Nived;Afsal, V. T. Ibrahim;Jamal, Farisha;Rasheed, Rinsha;Shahana, Sherin P. P.. And the article was included in World Journal of Pharmaceutical Research in 2022.Application In Synthesis of Glyceryl monostearate The following contents are mentioned in the article:

The skin is the largest organ of the body. There are three structural layers for skin-epidermis, dermis, and subcutis. Hair, nails, sebaceous gland, sweat gland and apocrine glands are regarded as derivatives of skin. There are different types of skin problems and the surge for discovering natural products. skin problem is one of the major problems in both mens and women. It may be due to certain hereditary factors, stress, alc. consumption, environmental factors etc This study aims to determine the potent skin care activity of herbal plant material, their extraction and to select the safest and effective formulation for their related problem. Crude drugs were obtained from local vendors. plant Curcuma longa (turmeric), Azadirachta indica (Neem) was collected and were carried out and formulated. The present work aimed to formulate herbal vanishing cream having antibacterial properties. Herbal vanishing cream is an o/w type emulsion formulated by using neem and turmeric. Then it is evaluated by using various parameters like appearance, pH, irritancy, smear test, spreadability etc. Antibacterial property of herbal vanishing cream was proved by using microbial assay. Hence it is confirmed that the formulated herbal vanishing cream shows better antibacterial properties, skin moisturizer, sheen effect, daily day creams, moisture locking power etc. This study involved multiple reactions and reactants, such as Glyceryl monostearate (cas: 31566-31-1Application In Synthesis of Glyceryl monostearate).

Glyceryl monostearate (cas: 31566-31-1) belongs to esters. Carboxylic acid esters of low molecular weight are colourless, volatile liquids with pleasant odours, slightly soluble in water. Many esters have the potential for conformational isomerism, but they tend to adopt an s-cis (or Z) conformation rather than the s-trans (or E) alternative, due to a combination of hyperconjugation and dipole minimization effects. The preference for the Z conformation is influenced by the nature of the substituents and solvent, if present. Lactones with small rings are restricted to the s-trans (i.e. E) conformation due to their cyclic structure.Application In Synthesis of Glyceryl monostearate

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Bouzeko, Inest Larissa T. et al. published their research in Biochemical Systematics and Ecology in 2021 | CAS: 31566-31-1

Glyceryl monostearate (cas: 31566-31-1) belongs to esters. Esters perform as high-grade solvents for a broad array of plastics, plasticizers, resins, and lacquers, and are one of the largest classes of synthetic lubricants on the commercial market. Polyesters are important plastics, with monomers linked by ester moieties. Esters contain a carbonyl center, which gives rise to 120° C–C–O and O–C–O angles. Unlike amides, esters are structurally flexible functional groups because rotation about the C–O–C bonds has a low barrier. Their flexibility and low polarity is manifested in their physical properties; they tend to be less rigid (lower melting point) and more volatile (lower boiling point) than the corresponding amides. Recommanded Product: Glyceryl monostearate

Chemical constituents of Mussaenda erythrophylla Schumach. & Thonn. (Rubiaceae) and their chemophenetic significance was written by Bouzeko, Inest Larissa T.;Dongmo, Faustine Leonie M.;Ndontsa, Blanche Laure;Ngansop, Cyrille Armel N.;Keumoe, Rodrigue;Bitchagno, Gabin Thierry M.;Jouda, Jean Bosco;Mbouangouere, Roukayatou;Tchegnitegni, Billy Toussie;Boyom, Fabrice Fekam;Sewald, Norbert;Lenta, Bruno Ndjakou;Tane, Pierre;Ngouela, Silvere Augustin;Tene, Mathieu. And the article was included in Biochemical Systematics and Ecology in 2021.Recommanded Product: Glyceryl monostearate The following contents are mentioned in the article:

The chem. investigation of the CH2Cl2/MeOH (1:1) extract from the aerial part of Mussaenda erythrophylla Schumach. & Thonn. (Rubiaceae) resulted in the isolation of sixteen known compounds (1-16) distributed in coumarins, flavonoid glucosides, quinic acid derivatives, triterpenoids, monoglycerid, steroids, tetraterpenoid and polyol. The structures of the compounds were determined by spectrometric and spectroscopic anal. including MS and NMR data followed by their comparison with reported ones in the literature. The chemophenetic significance of the isolated compounds was discussed. The crude extract and some of the isolated compounds were assessed in vitro for their antileishmanial, cytotoxic and antiplasmodial activities. The crude extract of M. erythrophylla showed moderate antileishmanial activity (IC50 = 61.6μg/mL) while the hexane soluble fraction showed good antileishmanial activity (IC50 = 31.06μg/mL) compared to the reference drug amphotericin B (IC50 = 0.11μM). Compounds 11 and 9 also exhibited potent antileishmanial activity (IC50 = 53.7-52.0μM). The crude extract as well as the Et acetate soluble fraction also exhibited good antiplasmodial activity (IC50 = 7.43 ± 0.00μg/mL and 14.49 ± 2.96μg/mL resp.), while compounds 11, 15 and 16 showed weak activity with IC50 > 20μM compared to the reference drug artemisinin (IC50 = 0.014 ± 0.001μM). This study involved multiple reactions and reactants, such as Glyceryl monostearate (cas: 31566-31-1Recommanded Product: Glyceryl monostearate).

Glyceryl monostearate (cas: 31566-31-1) belongs to esters. Esters perform as high-grade solvents for a broad array of plastics, plasticizers, resins, and lacquers, and are one of the largest classes of synthetic lubricants on the commercial market. Polyesters are important plastics, with monomers linked by ester moieties. Esters contain a carbonyl center, which gives rise to 120° C–C–O and O–C–O angles. Unlike amides, esters are structurally flexible functional groups because rotation about the C–O–C bonds has a low barrier. Their flexibility and low polarity is manifested in their physical properties; they tend to be less rigid (lower melting point) and more volatile (lower boiling point) than the corresponding amides. Recommanded Product: Glyceryl monostearate

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Plyduang, Thipapun et al. published their research in Cosmetics in 2022 | CAS: 31566-31-1

Glyceryl monostearate (cas: 31566-31-1) belongs to esters. Carboxylic acid esters of low molecular weight are colourless, volatile liquids with pleasant odours, slightly soluble in water. Acyl chlorides and acid anhydrides alcoholysis is another way to produce esters. Acyl chlorides and acid anhydrides react with alcohols to produce esters. Anydrous conditions are recommended since both acyl chlorides and acid anhydrides react with water.Recommanded Product: Glyceryl monostearate

Formula Development of Red Palm (Elaeis guineensis) Fruit Extract Loaded with Solid Lipid Nanoparticles Containing Creams and Its Anti-Aging Efficacy in Healthy Volunteers was written by Plyduang, Thipapun;Atipairin, Apichart;Sae Yoon, Attawadee;Sermkaew, Namfa;Sakdiset, Pajaree;Sawatdee, Somchai. And the article was included in Cosmetics in 2022.Recommanded Product: Glyceryl monostearate The following contents are mentioned in the article:

Palm fruits (Elaeis guineensis) comprise antioxidants that can be used as skin care agents. This study developed a cosmeceutical cream containing E. guineensis extract, loaded with solid lipid nanoparticles (SLNs), and assessed its efficacy on female volunteers. The E. guineensis extract exhibited a good antioxidant activity with high levels of vitamin E, β-carotene, and palmitic acid. Day and night creams containing E. guineensis fruit extract, loaded with SLNs, were formulated and exhibited acceptable phys. characteristics and good stability. Subsequently, their clin. efficacy and safety were evaluated on female volunteers. Both creams were non-irritating and had good cutaneous compatibility. Skin hydration, transepidermal water loss (TEWL), skin elasticity, melanin index, and skin texture were measured before and 30 min after the first application, as well as after 7, 14, and 30 days of daily application. A satisfactory survey was implemented using a questionnaire, and volunteer satisfaction scores were high for the product’s performance. Overall, the results showed that skin hydration, TEWL, cutaneous elasticity, and melanin index were improved, compared to the baseline data, after 30 days. Thus, the formulated facial day and night creams made the skin moist, reduced wrinkles, increased elasticity, and cleared the skin to the consumers’ satisfaction. This study involved multiple reactions and reactants, such as Glyceryl monostearate (cas: 31566-31-1Recommanded Product: Glyceryl monostearate).

Glyceryl monostearate (cas: 31566-31-1) belongs to esters. Carboxylic acid esters of low molecular weight are colourless, volatile liquids with pleasant odours, slightly soluble in water. Acyl chlorides and acid anhydrides alcoholysis is another way to produce esters. Acyl chlorides and acid anhydrides react with alcohols to produce esters. Anydrous conditions are recommended since both acyl chlorides and acid anhydrides react with water.Recommanded Product: Glyceryl monostearate

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Musielak, Ewelina et al. published their research in Molecules in 2022 | CAS: 31566-31-1

Glyceryl monostearate (cas: 31566-31-1) belongs to esters. Esters are also usually derived from carboxylic acids. It may also be obtained by reaction of acid anhydride or acid halides with alcohols or by the reaction of salts of carboxylic acids with alkyl halides. Esters are more polar than ethers but less polar than alcohols. They participate in hydrogen bonds as hydrogen-bond acceptors, but cannot act as hydrogen-bond donors, unlike their parent alcohols. This ability to participate in hydrogen bonding confers some water-solubility.Recommanded Product: 31566-31-1

Optimization of the Conditions of Solid Lipid Nanoparticles (SLN) Synthesis was written by Musielak, Ewelina;Feliczak-Guzik, Agnieszka;Nowak, Izabela. And the article was included in Molecules in 2022.Recommanded Product: 31566-31-1 The following contents are mentioned in the article:

Solid lipid nanoparticles (SLNs) have been synthesized as potential drug delivery systems. They are classified as solid lipid nanocarriers that can successfully carry both hydrophilic and hydrophobic drugs. SLNs are based on a biocompatible lipid matrix that is enzymically degraded into natural components found in the human body. Solid lipid nanoparticles are suitable for the incorporation of hydrophobic active ingredients such as curcumin. The study included the optimization of lipid nanoparticle composition, incorporation of the active compound (curcumin), a stability evaluation of the obtained nanocarriers and characterization of their lipid matrix. Through process optimization, a dispersion of solid lipid nanoparticles (solid lipid:surfactant-2:1.25 weight ratio) predisposed to the incorporation of curcumin was developed. The encapsulation efficiency of the active ingredient was determined to be 99.80%. In stability studies, it was found that the most suitable conditions for conducting high-pressure homogenization are 300 bar pressure, three cycles and a closed-loop system. This yields the required values of the physicochem. parameters (a particle size within a 200-450 nm range; a polydispersity index of <30%; and a zeta potential of about |±30 mV|). In this work, closed-loop high-pressure homogenization was used for the first time and compared to the currently preferred open-loop method. This study involved multiple reactions and reactants, such as Glyceryl monostearate (cas: 31566-31-1Recommanded Product: 31566-31-1).

Glyceryl monostearate (cas: 31566-31-1) belongs to esters. Esters are also usually derived from carboxylic acids. It may also be obtained by reaction of acid anhydride or acid halides with alcohols or by the reaction of salts of carboxylic acids with alkyl halides. Esters are more polar than ethers but less polar than alcohols. They participate in hydrogen bonds as hydrogen-bond acceptors, but cannot act as hydrogen-bond donors, unlike their parent alcohols. This ability to participate in hydrogen bonding confers some water-solubility.Recommanded Product: 31566-31-1

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Harinkhede, Neesha B. et al. published their research in World Journal of Pharmaceutical Research in 2022 | CAS: 31566-31-1

Glyceryl monostearate (cas: 31566-31-1) belongs to esters. Esters typically have a pleasant smell; those of low molecular weight are commonly used as fragrances and are found in essential oils and pheromones. Because of their lack of hydrogen-bond-donating ability, esters do not self-associate. Consequently, esters are more volatile than carboxylic acids of similar molecular weight.Formula: C21H44O5

Formulation and evaluation of polyherbal emulgel for rheumatoid arthritis was written by Harinkhede, Neesha B.;Avari, Jasmine G.;Mahakal, Nilesh S.. And the article was included in World Journal of Pharmaceutical Research in 2022.Formula: C21H44O5 The following contents are mentioned in the article:

The present study was conducted to develop an emulgel formulation containing potential herbal anti-inflammatory agent viz., turmeric, ginger, black paper, menthol. Inflammation and rheumatism remain serious problem in the present era. Although there are number of allopathic formulation available in market for the treatment of inflammation, but these suffer from side effects like heartburn, stomach pain, nausea, vomiting, diarrhea, constipation, liver damage, fluid retention, nephrotoxiciy, etc. It is considered that the herbal medication as safer as compared to that of allopathic medicine in the market. The herbal components ginger, turmeric, black paper menthol has been selected for the development of anti-inflammatory formulation, as from literature review it revealed that these are effective in the treatment of inflammation. Ultrez 20 (corbomer) was used as gelling agent ultrez 20 has several advantages over traditional corbopol, ultrez 20 wet within a 5 min whereas traditional corbopol take 12-15 h for wetting. The emulgel were subjected for evaluation on the basis of appearance, pH, spreadability, extrudability, rheol. behavior, in vitro release performance, anti-inflammatory study and were compared with marketed preparation containing diclofenac sodium. The anti-inflammatory study suggests that formulation emulgel is superior to that of all formulation including marketed gel and emulgel. This study involved multiple reactions and reactants, such as Glyceryl monostearate (cas: 31566-31-1Formula: C21H44O5).

Glyceryl monostearate (cas: 31566-31-1) belongs to esters. Esters typically have a pleasant smell; those of low molecular weight are commonly used as fragrances and are found in essential oils and pheromones. Because of their lack of hydrogen-bond-donating ability, esters do not self-associate. Consequently, esters are more volatile than carboxylic acids of similar molecular weight.Formula: C21H44O5

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics