Category: 31273-66-2

New learning discoveries about 31273-66-2

Adding a certain compound to certain chemical reactions, such as: 31273-66-2, name is Ethyl 2,3-dichlorobenzoate, belongs to esters-buliding-blocks compound, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 31273-66-2, Safety of Ethyl 2,3-dichlorobenzoate

Adding a certain compound to certain chemical reactions, such as: 31273-66-2, name is Ethyl 2,3-dichlorobenzoate, belongs to esters-buliding-blocks compound, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 31273-66-2, Safety of Ethyl 2,3-dichlorobenzoate

General procedure: A mixture of substituted ethyl benzoate (12a-g) (0.1M) and hydrazine hydrate (0.3M) was heated under reflux for 30min. Ethanol (20mL) was added to the refluxing mixture as a solvent in order to homogenize the solution, the resulting mixture was further allowed for 6h. Excess of ethanol was distilled out and the content was allowed to cool. The crystals formed were filtered and washed thoroughly with water and dried.

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Reference:
Article; Rakse, Monika; Karthikeyan, Chandrabose; Deora, Girdhar Singh; Moorthy; Rathore, Vandana; Rawat, Arun K.; Srivastava; Trivedi, Piyush; European Journal of Medicinal Chemistry; vol. 70; (2013); p. 469 – 476;,
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

The important role of Ethyl 2,3-dichlorobenzoate

Researchers who often do experiments know that organic synthesis is a process of preparing more complex target molecules from simple raw materials through one or more chemical reactions. Generally, it requires fewer steps, and cheap raw materials. 31273-66-2, name is Ethyl 2,3-dichlorobenzoate, A new synthetic method of this compound is introduced below., name: Ethyl 2,3-dichlorobenzoate

Researchers who often do experiments know that organic synthesis is a process of preparing more complex target molecules from simple raw materials through one or more chemical reactions. Generally, it requires fewer steps, and cheap raw materials. 31273-66-2, name is Ethyl 2,3-dichlorobenzoate, A new synthetic method of this compound is introduced below., name: Ethyl 2,3-dichlorobenzoate

General procedure: In a fume hood, an oven dried Schlenk flask equipped with a magnetic stirring bar was filled with N2 and evacuated (three cycles). Under N2 atmosphere [Ir(OMe)(COD)]2 (13.3 mg, 0.01 mmol, 1 mol%), 4,4-ditert-butyl-2,2?-bipyridyl (10.7 mg, 0.02 mmol, 2 mol%), and pinacolborane (HBPin) (436 muL, 384 mg, 3 mmol, 1.5 equiv) were added. The appropriate arene substrate (2 mmol, 1 equiv) was added via micropipette under N2 atmosphere. The Schlenk flask was closed and the reaction mixture was heated at 80 C in an oil bath. The progress of reaction was monitored by GC-MS and TLC. Upon completion of reaction, Schlenk flask was cooled to r.t. and exposed to air. The contents of the flask were dissolved in CH2Cl2 (3-5 mL) and taken out in a round-bottomed flask. The volatile organics were removed under reduced pressure using a rotary evaporator. The crude product was purified by column chromatography (silica gel, hexanes-CH2Cl2 1:1).

The synthetic route of 31273-66-2 has been constantly updated, and we look forward to future research findings.

Reference:
Article; Shahzadi, Tayyaba; Saleem, Rahman S. Z.; Chotana, Ghayoor A.; Synthesis; vol. 50; 21; (2018); p. 4336 – 4342;,
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics