Discovery of Methyl 2-benzylacrylate

Adding a certain compound to certain chemical reactions, such as: 3070-71-1, name is Methyl 2-benzylacrylate, belongs to esters-buliding-blocks compound, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 3070-71-1, Quality Control of Methyl 2-benzylacrylate

Adding a certain compound to certain chemical reactions, such as: 3070-71-1, name is Methyl 2-benzylacrylate, belongs to esters-buliding-blocks compound, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 3070-71-1, Quality Control of Methyl 2-benzylacrylate

(1) Compound (7) (239.7 mg, 0.93 mmol) obtained in Example 7 was dissolved in dehydrated toluene (5.0 mL), Compound (4) (R2=Bn, R=Me) (530 mg, 3.0 mmol) synthesized according to a method of Basavaiah et al. (Tetrahedron Lett. Vol. 42, 477-479 (2001)) was added to the solution, and the mixture was stirred for 12 hr at 60 C. under nitrogen atmosphere and further for 2 hr at 90 C. The reaction mixture was concentrated in vacuo, and the obtained residue was purified by silica gel column chromatography (n-hexane:ethyl acetate=20:1) to obtain a crude body of Compound (8) (R1=Ph(CH2)2, R2=Bn, R=Me).

In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles, Methyl 2-benzylacrylate, other downstream synthetic routes, hurry up and to see.

Reference:
Patent; TEIJIN PHARMA LIMITED; US2005/182032; (2005); A1;,
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics