Category: 30414-53-0

Dong, Kuiyong; Marichev, Kostiantyn O.; Xu, Xingfang; Doyle, Michael P. published an article in Synlett. The title of the article was 《High Stereocontrol in the Preparation of Silyl-Protected γ-Substituted Enoldiazoacetates》.Reference of Methyl 3-oxovalerate The author mentioned the following in the article:

A robust and efficient synthesis of triisopropylsilyl (TIPS)-protected γ-substituted enoldiazoacetates with excellent Z stereocontrol by using Li bis(trimethylsilyl)azanide (LiHMDS) as a base and TIPSOTf as a silyl transfer reagent is reported. Despite their increased size compared to previously tert-butyldimethylsilyl (TBS)-protected γ-unsubstituted enoldiazoacetates, a high product yield with exceptional stereocontrol was achieved in Cu-catalyzed [3+3] cycloaddition reaction with nitrones by using a chiral indeno bisoxazoline ligand. In the experiment, the researchers used many compounds, for example, Methyl 3-oxovalerate(cas: 30414-53-0Reference of Methyl 3-oxovalerate)

Methyl 3-oxovalerate(cas: 30414-53-0) belongs to ketone compounds. Ketone compounds have important physiological properties. They are found in several sugars and in compounds for medicinal use, including natural and synthetic steroid hormones. Molecules of the anti-inflammatory agent cortisone contain three ketone groups.Reference of Methyl 3-oxovalerate

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

The author of 《Domino Nitro Reduction-Friedlander Heterocyclization for the Preparation of Quinolines》 were Fobi, Kwabena; Bunce, Richard A.. And the article was published in Molecules in 2022. Quality Control of Methyl 3-oxovalerate The author mentioned the following in the article:

The Friedlander synthesis offers efficient access to substituted quinolines from 2-aminobenzaldehydes and activated ketones in the presence of a base. The disadvantage of this procedure lies in the fact that relatively few 2-aminobenzaldehyde derivatives are readily available. To overcome this problem, authors report a modification of this process involving the in situ reduction of 2-nitrobenzaldehydes with Fe/AcOH in the presence of active methylene compounds (AMCs) to produce substituted quinolines in high yields. The conditions are mild enough to tolerate a wide range of functionality in both reacting partners and promote reactions not only with Ph and benzyl ketones, but also with β-keto-esters, β-keto-nitriles, β-keto-sulfones and β-diketones. The reaction of 2-nitroarom. ketones with unsym. AMCs is less reliable, giving a competitive formation of substituted quinolin-2(1H)-ones from the cyclization of the Z Knoevenagel intermediate which appears to be favored when certain large groups are adjacent to the AMC ketone carbonyl. In the experimental materials used by the author, we found Methyl 3-oxovalerate(cas: 30414-53-0Quality Control of Methyl 3-oxovalerate)

Methyl 3-oxovalerate(cas: 30414-53-0) belongs to ketone compounds. Ketone compounds have important physiological properties. They are found in several sugars and in compounds for medicinal use, including natural and synthetic steroid hormones. Molecules of the anti-inflammatory agent cortisone contain three ketone groups.Quality Control of Methyl 3-oxovalerate

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Name: Methyl 3-oxovalerateOn May 18, 2021 ,《Design, Synthesis, and Structure-Activity Relationship Study of Pyrazolones as Potent Inhibitors of Pancreatic Lipase》 appeared in ChemMedChem. The author of the article were Zhang, Jing; Yang, Yang; Qian, Xing-Kai; Song, Pei-Fang; Zhao, Yi-Shu; Guan, Xiao-Qing; Zou, Li-Wei; Bao, Xiaoze; Wang, Hong. The article conveys some information:

In this study, a series of pyrazolones was synthesized, and their inhibitory effects against pancreatic lipase (PL) were assayed by using 4-methylumbelliferyl oleate (4-MUO) as optical substrate for PL. Comprehensive structure-activity relationship anal. of these pyrazolones led us to design and synthesize a novel compound I as a potent mixed-competitive inhibitor of PL (IC50=0.30μM). In addition, compound I displayed some selectivity over other known serine hydrolases. A mol. docking study for compound I demonstrated that the inhibitory activity of compound I towards PL could be attributed to the π-π interactions of 2-naphthyl unit and hydrophobic interactions of Ph moiety with the active site of PL. Thus, compound I could serve as promising lead compound for the development of more efficacious and selective pyrazolones-type PL inhibitors for biomedical applications. In the experimental materials used by the author, we found Methyl 3-oxovalerate(cas: 30414-53-0Name: Methyl 3-oxovalerate)

Methyl 3-oxovalerate(cas: 30414-53-0) belongs to ketone compounds. Ketone compounds have important physiological properties. They are found in several sugars and in compounds for medicinal use, including natural and synthetic steroid hormones. Molecules of the anti-inflammatory agent cortisone contain three ketone groups.Name: Methyl 3-oxovalerate

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

《Stereodiverse Iterative Synthesis of 1,3-Polyol Arrays through Asymmetric Catalytic Hydrogenation. Formal Total Synthesis of (-)-Cyanolide A》 was written by Che, Wen; Li, Yu-Zhen; Liu, Jin-Chi; Zhu, Shou-Fei; Xie, Jian-Hua; Zhou, Qi-Lin. Quality Control of Methyl 3-oxovalerate And the article was included in Organic Letters on April 5 ,2019. The article conveys some information:

An iterative protocol was developed for highly diastereo- and enantioselective construction of high-order 1,3-polyols via iridium-catalyzed asym. hydrogenation of β-alkyl-β-keto esters. The protocol involves four operations-asym. hydrogenation, hydroxy protection, ester hydrolysis, and C-acylation-and the catalyst loading can be as low as 0.005 mol %. The configurations of all stereogenic centers of 1,3-polyols are controlled by the catalyst. By the use of this protocol, a formal total synthesis of the polyketide cyanolide A was achieved with high diastereoselectivity and enantioselectivity. In the experiment, the researchers used many compounds, for example, Methyl 3-oxovalerate(cas: 30414-53-0Quality Control of Methyl 3-oxovalerate)

Methyl 3-oxovalerate(cas: 30414-53-0) belongs to ketone compounds. They are most widely used as solvents, especially in industries manufacturing explosives, lacquers, paints, and textiles. Ketones are also used in tanning, as preservatives, and in hydraulic fluids.Quality Control of Methyl 3-oxovalerate

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

The author of 《Synthesis of quinazolinone derivatives catalyzed by alkaline protease》 were Xie, Zongbo; Li, Hongxia; Liu, Liansheng; Lan, Jin; Hu, Zhiyu; Le, Zhanggao. And the article was published in Youji Huaxue in 2019. Recommanded Product: Methyl 3-oxovalerate The author mentioned the following in the article:

Alk. protease-catalyzed synthesis of quinazolinone derivatives I [R = H, 7-Me, 6-Cl; R1 = Me, Et, n-Pr; R2 = Me, Et] was developed between β-keotesters and o-aminobenzamides. Because ethanol is one kind of eco-friendly solvents, this method could reduce the impact of solvents on the environment. Alk. protease as a biocatalyst had many advantages, e.g. high catalytic activity, environmentally friendly, wide variety of sources and simple operation. In addition, a variety of quinazolinone derivatives was obtained with good to excellent yields just using 2000 U alk. protease as catalyst. In the experimental materials used by the author, we found Methyl 3-oxovalerate(cas: 30414-53-0Recommanded Product: Methyl 3-oxovalerate)

Methyl 3-oxovalerate(cas: 30414-53-0) belongs to ketone compounds. Ketone compounds have important physiological properties. They are found in several sugars and in compounds for medicinal use, including natural and synthetic steroid hormones. Molecules of the anti-inflammatory agent cortisone contain three ketone groups.Recommanded Product: Methyl 3-oxovalerate

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Name: Methyl 3-oxovalerateOn November 15, 2019 ,《Cu-Catalyzed Denitrogenative Transannulation of 3-Aminoindazoles To Assemble 1-Aminoisoquinolines and 3-Aminobenzothiophenes》 appeared in Organic Letters. The author of the article were Zhou, Yao; Wang, Ya; Lou, Yixian; Song, Qiuling. The article conveys some information:

Discloses is a Cu-catalyzed denitrogenative transannulation of 3-aminoindazoles to afford diverse functionalized 3-aminobenzothiophenes and 1-aminoisoquinolines. This transformation proceeds via an “”extrude-and-sew”” strategy with an unprecedented radical reactivity of 3-aminoindazoles. In the part of experimental materials, we found many familiar compounds, such as Methyl 3-oxovalerate(cas: 30414-53-0Name: Methyl 3-oxovalerate)

Methyl 3-oxovalerate(cas: 30414-53-0) belongs to ketone compounds. Ketone compounds have important physiological properties. They are found in several sugars and in compounds for medicinal use, including natural and synthetic steroid hormones. Molecules of the anti-inflammatory agent cortisone contain three ketone groups.Name: Methyl 3-oxovalerate

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

In 2020,RSC Advances included an article by Yang, Han-Lin; Xu, Li-Jun; Li, Wen-Zhong; Sun, Tao; Duan, Bao-Rong; Chen, Si; Gao, Xiang. HPLC of Formula: 30414-53-0. The article was titled 《Base-iodine-promoted metal-catalyst-free reactions of [60]fullerene with β-keto esters for the selective formation of [60]fullerene derivatives》. The information in the text is summarized as follows:

Methanofullerenes and 2′,3′-dihydrofuran C60derivatives were selectively synthesized in high yields via the reactions of C60with β-keto esters under mild conditions by controlling the addition sequence and molar ratio of iodine and base. The structures of the products were determined by spectroscopic characterization. Moreover, a possible reaction mechanism for the selective formation of fullerene derivatives was proposed. In the part of experimental materials, we found many familiar compounds, such as Methyl 3-oxovalerate(cas: 30414-53-0HPLC of Formula: 30414-53-0)

Methyl 3-oxovalerate(cas: 30414-53-0) belongs to ketone compounds. Ketone compounds have important physiological properties. They are found in several sugars and in compounds for medicinal use, including natural and synthetic steroid hormones. Molecules of the anti-inflammatory agent cortisone contain three ketone groups.HPLC of Formula: 30414-53-0

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Han, Chunyu; Tian, Xianhai; Zhang, Huili; Rominger, Frank; Hashmi, A. Stephen K. published an article in Organic Letters. The title of the article was 《Tetrasubstituted 1,3-Enynes by Gold-Catalyzed Direct C(sp2)-H Alkynylation of Acceptor-Substituted Enamines》.HPLC of Formula: 30414-53-0 The author mentioned the following in the article:

A gold-catalyzed synthesis of tetrasubstituted 1,3-enynes from hypervalent iodine(III) reagents and activated alkenes is reported. This reaction involves an in situ formed alkynyl Au(III) species and a subsequent direct C(sp2)-H functionalization of alkenes, offering 26 enynes in 62-92% yield with excellent functional group tolerance. In the experiment, the researchers used many compounds, for example, Methyl 3-oxovalerate(cas: 30414-53-0HPLC of Formula: 30414-53-0)

Methyl 3-oxovalerate(cas: 30414-53-0) belongs to ketone compounds. Ketone compounds have important physiological properties. They are found in several sugars and in compounds for medicinal use, including natural and synthetic steroid hormones. Molecules of the anti-inflammatory agent cortisone contain three ketone groups.HPLC of Formula: 30414-53-0

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Recommanded Product: Methyl 3-oxovalerateOn September 17, 2019 ,《Synthetic Strategy for Pyrazolo[1,5-a]pyridine and Pyrido[1,2-b]indazole Derivatives through AcOH and O2-Promoted Cross-dehydrogenative Coupling Reactions between 1,3-Dicarbonyl Compounds and N-Amino-2-iminopyridines》 was published in ACS Omega. The article was written by Behbehani, Haider; Ibrahim, Hamada Mohamed. The article contains the following contents:

An efficient method has been developed for the synthesis of uniquely substituted pyrazolo[1,5-a]pyridine and pyrido[1,2-b]indazole derivatives, which involves acetic acid and mol. oxygen promoted cross-dehydrogenative coupling reactions of resp. β-ketoesters and β-diketones (like Et acetoacetate, Et benzoylacetate, Me propionylacetate, acetylacetone, dimedone, 1,3-cyclohexanedione, and 1,3-cyclopentanedione) with N-amino-2-iminopyridines. The proposed tentative mechanism involves formal acetic acid-promoted oxidative C(sp3)-C(sp2) dehydrogenative coupling followed by dehydrative cyclization under a catalyst-free condition within high atom economy processes. In the experimental materials used by the author, we found Methyl 3-oxovalerate(cas: 30414-53-0Recommanded Product: Methyl 3-oxovalerate)

Methyl 3-oxovalerate(cas: 30414-53-0) belongs to ketone compounds. Ketone compounds have important physiological properties. They are found in several sugars and in compounds for medicinal use, including natural and synthetic steroid hormones. Molecules of the anti-inflammatory agent cortisone contain three ketone groups.Recommanded Product: Methyl 3-oxovalerate

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

《Fe-Catalyzed Dicarbofunctionalization of Vinylarenes with Alkylsilyl Peroxides and β-Keto Carbonyl Substrates》 was written by Xu, Weiping; Kato, Terumasa; Liu, Yan; Matsumoto, Akira; Maruoka, Keiji. Electric Literature of C6H10O3 And the article was included in Organic Letters on April 15 ,2022. The article conveys some information:

The formation of two carbon-carbon bonds using vinylarenes with alkylsilyl peroxides and β-keto carbonyl substrates is effected in the presence of catalytic Fe(OTf)2 under mild reaction conditions. A variety of vinylarenes with different substituents can be utilized in combination with several different alkylsilyl peroxides and β-keto carbonyl substrates. The experimental process involved the reaction of Methyl 3-oxovalerate(cas: 30414-53-0Electric Literature of C6H10O3)

Methyl 3-oxovalerate(cas: 30414-53-0) belongs to ketone compounds. They are most widely used as solvents, especially in industries manufacturing explosives, lacquers, paints, and textiles. Ketones are also used in tanning, as preservatives, and in hydraulic fluids.Electric Literature of C6H10O3

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics