2495-35-4 Archives - Page 7 of 10 - Esters-buliding-blocks

Seo, Dongjin’s team published research in Journal of Colloid and Interface Science in 2020 | CAS: 2495-35-4

Benzyl acrylate(cas: 2495-35-4) is a reagent that can be used in the preparation of 2-(Phosphonomethyl)pentanedioic Acid, a selective glutamate carboxypeptidase 2 (GCP-II) inhibitor. It can also be used in the preparation of high refractive index polyacrylates.COA of Formula: C10H10O2

《The shape and dynamics of deformations of viscoelastic fluids by water droplets》 was written by Seo, Dongjin; Chen, Szu-Ying; Lee, Dong Woog; Schrader, Alex M.; Ahn, Kollbe; Page, Steve; Koenig, Peter H.; Gizaw, Yonas; Israelachvili, Jacob N.. COA of Formula: C10H10O2This research focused onviscoelasticity water drop deformation polymer surface structure; Deformation from surface tension; Neumann angle; Surface tension imbalance; Wetting on soft surface. The article conveys some information:

Many studies on the deformation of soft films by liquids confirmed the increase in the radius of the deformation and the decrease in the apparent contact angle. However, due to the thinness, the dynamics of the deformation could not be observed until the thermodn. equilibrium Thus, the dynamics on thick soft materials was studied until equilibrium to contrast the effect of different interfacial energy between different soft materials and water. Therefore, we prepared two different polymeric fluids with similar rheol. by crosslinking monomers, yet with different contact angles with water. Sometime after water droplets were placed on these thick polymers, 3D profiles of the deformation were recorded. Though the effect of the surface tension was not verified, the same trend in the dynamics was observed as with thin films, except for the decrease in the radius after the initial increase. The three-phase boundaries (TPBs) were found not at the apex of the ridges formed during the transition to equilibrium By calculating the surface tensions and angles of each interface at the equilibrium, we found that the temporary imbalance among surface tensions induced the slip of the TPBs toward the center of water droplets, thus dislocating the TPBs and decreasing the radius. The experimental process involved the reaction of Benzyl acrylate(cas: 2495-35-4COA of Formula: C10H10O2)

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Furukawa, Yuji’s team published research in ACS Sustainable Chemistry & Engineering in 2020 | CAS: 2495-35-4

Benzyl acrylate(cas: 2495-35-4) has been used in preparation of high refractive index polyacrylates. Benzyl acrylate is used in the preparation of heptanoic acid benzyl ester. It is used to prepare polybenzylacrylate using azobisisobutyronitrile as initiator.Synthetic Route of C10H10O2

《Visible-Light-Driven Direct 2,2-Difluoroacetylation Using an Organic Pigment Catalyst》 was published in ACS Sustainable Chemistry & Engineering in 2020. These research results belong to Furukawa, Yuji; Hayashi, Masayuki; Hayase, Shuichi; Nokami, Toshiki; Itoh, Toshiyuki. Synthetic Route of C10H10O2 The article mentions the following:

Et 2-bromo-2,2-difluoroacetate reacted with alkenes during irradiation by a blue light-emitting diode (LED; 470 nm) in the presence of 10 mol% fluorescein to achieved the visible-light-driven direct 2,2-difluoroacetylation; the combination of N,N,N,N-tetramethylethylenediamine (TMEDA) as a reducing agent and 1-methyl-2-pyrrolidinone (NMP) as a solvent was essential to afford 10 types of desired compounds 2,2-difluoroalkanoates were obtained in moderate to excellent yields. The same reaction conditions were applicable to the 2,2-difluoroacetylation of alkynes to attain 10 types of 2,2-difluoroalkenoates in moderate to excellent yields. Metal-catalyst-free radical reactions under visible light irradiation conditions allowed to direct 2,2-difluoroacetylation with alkenes or alkynes. The experimental part of the paper was very detailed, including the reaction process of Benzyl acrylate(cas: 2495-35-4Synthetic Route of C10H10O2)

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Zhan, Bei-Bei’s team published research in Angewandte Chemie, International Edition in 2020 | CAS: 2495-35-4

《Synthesis of Axially Chiral Biaryl-2-amines by PdII-Catalyzed Free-Amine-Directed Atroposelective C-H Olefination》 was published in Angewandte Chemie, International Edition in 2020. These research results belong to Zhan, Bei-Bei; Wang, Lei; Luo, Jun; Lin, Xu-Feng; Shi, Bing-Feng. Synthetic Route of C10H10O2 The article mentions the following:

A simple and ubiquitously present group, free amine, is used as a directing group to synthesize axially chiral biaryl compounds by PdII-catalyzed atroposelective C-H olefination. A broad range of axially chiral biaryl-2-amines can be obtained in good yields with high enantioselectivities (up to 97% ee). Chiral spiro phosphoric acid (SPA) proved to be an efficient ligand and the loading could be reduced to 1 mol % without erosion of enantiocontrol in gram-scale synthesis. The resulting axially chiral biaryl-2-amines also provide a platform for the synthesis of a set of chiral ligands.Benzyl acrylate(cas: 2495-35-4Synthetic Route of C10H10O2) was used in this study.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Verma, Pritha’s team published research in Journal of the American Chemical Society in 2020 | CAS: 2495-35-4

Recommanded Product: Benzyl acrylateIn 2020 ,《Iridium(I)-Catalyzed α-C(sp3)-H Alkylation of Saturated Azacycles》 was published in Journal of the American Chemical Society. The article was written by Verma, Pritha; Richter, Jeremy M.; Chekshin, Nikita; Qiao, Jennifer X.; Yu, Jin-Quan. The article contains the following contents:

Saturated azacycles are commonly encountered in bioactive compounds and approved therapeutic agents. The development of methods for functionalization of the α-methylene C-H bonds of these highly privileged building blocks is of great importance, especially in drug discovery. While much effort has been dedicated towards this goal of using a directed C-H activation approach, the development of directing groups that are both general, as well as practical, remains a significant challenge. Herein, the design and development of novel amidoxime directing groups is described for Ir(I)-catalyzed α-C(sp3)-H alkylation of saturated azacycles using readily available olefins as coupling partners. This protocol extends the scope of saturated azacycles to piperidines, azepane, and tetrahydroisoquinoline that are incompatible with our previously reported directing group. A variety of olefin coupling partners, including previously unreactive di-substituted terminal olefins and internal olefins, are compatible with this transformation. The selectivity for a branched α-C(sp3)-alkylation product is also observed for the first time when acrylate is used as the reaction partner. The development of practical, one-step installation and removal protocols further add to the utility of amidoxime directing groups. In the experiment, the researchers used many compounds, for example, Benzyl acrylate(cas: 2495-35-4Recommanded Product: Benzyl acrylate)

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Kim, Dongyoung’s team published research in Journal of the American Chemical Society in 2019 | CAS: 2495-35-4

The author of 《Roles of Iron Complexes in Catalytic Radical Alkene Cross-Coupling: A Computational and Mechanistic Study》 were Kim, Dongyoung; Rahaman, S. M. Wahidur; Mercado, Brandon Q.; Poli, Rinaldo; Holland, Patrick L.. And the article was published in Journal of the American Chemical Society in 2019. HPLC of Formula: 2495-35-4 The author mentioned the following in the article:

A growing and useful class of alkene coupling reactions involve hydrogen atom transfer (HAT) from a metal-hydride species to an alkene to form a free radical, which is responsible for subsequent bond formation. Here, we use a combination of exptl. and computational investigations to map out the mechanistic details of iron-catalyzed reductive alkene cross-coupling, an important representative of the HAT alkene reactions. We are able to explain several observations that were previously mysterious. First, the rate-limiting step in the catalytic cycle is the formation of the reactive Fe-H intermediate, elucidating the importance of the choice of reductant. Second, the success of the catalytic system is attributable to the exceptionally weak (17 kcal/mol) Fe-H bond, which performs irreversible HAT to alkenes in contrast to previous studies on isolable hydride complexes where this addition was reversible. Third, the organic radical intermediates can reversibly form organometallic species, which helps to protect the free radicals from side reactions. Fourth, the previously accepted quenching of the postcoupling radical through stepwise electron transfer/proton transfer is not as favorable as alternative mechanisms. We find that there are two feasible pathways. One uses concerted proton-coupled electron transfer (PCET) from an iron(II) ethanol complex, which is facilitated because the O-H bond dissociation free energy is lowered by 30 kcal/mol upon metal binding. In an alternative pathway, an O-bound enolate-iron(III) complex undergoes proton shuttling from an iron-bound alc. These kinetic, spectroscopic, and computational studies identify key organometallic species and PCET steps that control selectivity and reactivity in metal-catalyzed HAT alkene coupling, and create a firm basis for elucidation of mechanisms in the growing class of HAT alkene cross-coupling reactions. In addition to this study using Benzyl acrylate, there are many other studies that have used Benzyl acrylate(cas: 2495-35-4HPLC of Formula: 2495-35-4) was used in this study.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Wong, Chin Ken’s team published research in Angewandte Chemie, International Edition in 2019 | CAS: 2495-35-4

The author of 《Bioactive Patchy Nanoparticles with Compartmentalized Cargoes for Simultaneous and Trackable Delivery》 were Wong, Chin Ken; Chen, Fan; Walther, Andreas; Stenzel, Martina H.. And the article was published in Angewandte Chemie, International Edition in 2019. Safety of Benzyl acrylate The author mentioned the following in the article:

Recent years have seen an increased interest in the use of ABC triblock terpolymers to bottom-up assemble multicompartment patchy nanoparticles. Despite these exptl. and theor. efforts, the applications of polymer-based patchy nanoparticles remain rather limited. One of the major challenges that eclipses their potential is the lack of knowledge to selectively encapsulate cargoes within different compartments that are separated in the nanometer length scale. Here, strategies are reported to segregate two chem. distinct mols. in either the patches or core compartment of patchy nanoparticles that bear a (bioactive) sugar corona. The potential use of these bioactive patchy nanoparticles containing compartmentalized cargoes for simultaneous drug delivery with real-time release monitoring capabilities is further demonstrated. In addition to this study using Benzyl acrylate, there are many other studies that have used Benzyl acrylate(cas: 2495-35-4Safety of Benzyl acrylate) was used in this study.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Zheng, Songlin’s team published research in Angewandte Chemie, International Edition in 2020 | CAS: 2495-35-4

《Selective 1,2-Aryl-Aminoalkylation of Alkenes Enabled by Metallaphotoredox Catalysis》 was published in Angewandte Chemie, International Edition in 2020. These research results belong to Zheng, Songlin; Chen, Zimin; Hu, Yuanyuan; Xi, Xiaoxiang; Liao, Zixuan; Li, Weirong; Yuan, Weiming. Category: esters-buliding-blocks The article mentions the following:

A highly chemo- and regioselective intermol. 1,2-aryl-aminoalkylation of alkenes by photoredox/nickel dual catalysis is described here. This three-component conjunctive cross-coupling is highlighted by its first application of primary alkyl radicals, which were not compatible in previous reports. The readily prepared α-silyl amines could be transferred to α-amino radicals by photo-induced single electron transfer step. The radical addition/cross-coupling cascade reaction proceeds under mild, base-free and redox-neutral conditions with good functional group tolerance, and importantly, provides an efficient and concise method for the synthesis of structurally valuable α-aryl substituted γ-amino acid derivatives motifs. In addition to this study using Benzyl acrylate, there are many other studies that have used Benzyl acrylate(cas: 2495-35-4Category: esters-buliding-blocks) was used in this study.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Park, Han Seul’s team published research in Angewandte Chemie, International Edition in 2020 | CAS: 2495-35-4

《Distal γ-C(sp3)-H Olefination of Ketone Derivatives and Free Carboxylic Acids》 was published in Angewandte Chemie, International Edition in 2020. These research results belong to Park, Han Seul; Fan, Zhoulong; Zhu, Ru-Yi; Yu, Jin-Quan. COA of Formula: C10H10O2 The article mentions the following:

Reported herein is the distal γ-C(sp3)-H olefination of ketone derivatives and free carboxylic acids. Fine tuning of a previously reported imino-acid directing group and using the ligand combination of a mono-N-protected amino acid (MPAA) and an electron-deficient 2-pyridone were critical for the γ-C(sp3)-H olefination of ketone substrates. In addition, MPAAs enabled the γ-C(sp3)-H olefination of free carboxylic acids to form diverse six-membered lactones. Besides alkyl carboxylic acids, benzylic C(sp3)-H bonds also could be functionalized to form 3,4-dihydroisocoumarin structures in a single step from 2-Me benzoic acid derivatives The utility of these protocols was demonstrated in large scale reactions and diversification of the γ-C(sp3)-H olefinated products.Benzyl acrylate(cas: 2495-35-4COA of Formula: C10H10O2) was used in this study.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Zheng, Danqing’s team published research in Angewandte Chemie, International Edition in 2021 | CAS: 2495-35-4

《Photo-Mediated Intermolecular Coupling of Alkenes with Ketones via Acyloxy Nitroso Compounds》 was written by Zheng, Danqing; Ploeger, Stefanie; Daniliuc, Constantin G.; Studer, Armido. Application of 2495-35-4 And the article was included in Angewandte Chemie, International Edition in 2021. The article conveys some information:

An atom-economic intermol. radical addition reaction of acyloxy nitroso compounds such as I to electron-deficient alkenes such as Ph vinyl ketone mediated by visible light to yield δ-acyloxy β-ketocarbonyl compound monooximes such as II is reported. The starting nitroso derivatives are readily prepared by oxidation of the corresponding oximes prepared from ketones and the overall transformation represents an oxidative coupling of a ketone with a Michael acceptor. The cascade proceeds smoothly under mild conditions, providing a series of valuable functionalized oximes in moderate to good yields. Mechanistic studies suggest that these cascades proceed via addition/coupling processes that are controlled by the persistent radical effect (PRE) with NO acting as the persistent species. After reading the article, we found that the author used Benzyl acrylate(cas: 2495-35-4Application of 2495-35-4)

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Stache, Erin E.’s team published research in Journal of the American Chemical Society in 2020 | CAS: 2495-35-4

《Photocontrolled Radical Polymerization from Hydridic C-H Bonds》 was written by Stache, Erin E.; Kottisch, Veronika; Fors, Brett P.. Category: esters-buliding-blocks And the article was included in Journal of the American Chemical Society in 2020. The article conveys some information:

Given the ubiquity of carbon-hydrogen bonds in biomols. and polymer backbones, the development of a photocontrolled polymerization selectively grafting from a C-H bond represents a powerful strategy for polymer conjugation. This approach would circumvent the need for complex synthetic pathways currently used to introduce functionality at a polymer chain end. On this basis, we developed a hydrogen-atom abstraction strategy that allows for a controlled polymerization selectively from a hydridic C-H bond using a benzophenone photocatalyst, a trithiocarbonate-derived disulfide, and visible light. We performed the polymerization from a variety of ethers, alkanes, unactivated C-H bonds, and alcs. Our method lends itself to photocontrol which has important implications for building advanced macromol. architectures. Finally, we demonstrate that we can graft polymer chains controllably from poly(ethylene glycol) showcasing the potential application of this method for controlled grafting from C-H bonds of commodity polymers. The results came from multiple reactions, including the reaction of Benzyl acrylate(cas: 2495-35-4Category: esters-buliding-blocks)

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics