2495-35-4 Archives - Page 2 of 10 - Esters-buliding-blocks

Gao, Mingchun’s team published research in Organic Letters in 2019 | CAS: 2495-35-4

Benzyl acrylate(cas: 2495-35-4) has been used in preparation of high refractive index polyacrylates. Benzyl acrylate is used in the preparation of heptanoic acid benzyl ester. It is used to prepare polybenzylacrylate using azobisisobutyronitrile as initiator.Related Products of 2495-35-4

In 2019,Organic Letters included an article by Gao, Mingchun; Gan, Yuansheng; Xu, Bin. Related Products of 2495-35-4. The article was titled 《From Alkenes to Isoxazolines via Copper-Mediated Alkene Cleavage and Dipolar Cycloaddition》. The information in the text is summarized as follows:

An unprecedented copper-mediated anion transformation is reported, along with selective C=C double bond cleavage and dipolar cycloaddition reaction from simple alkenes and inexpensive copper nitrate. Various transformations demonstrate the generality of this method. Further mechanistic investigation indicates a novel ionic pathway for alkene cleavage and highlights the coeffect of iodide and boric acid as additives on the inhibition of well-documented competitive nitration byproducts. In the experiment, the researchers used Benzyl acrylate(cas: 2495-35-4Related Products of 2495-35-4)

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Dutta, Uttam’s team published research in Chemical Science in 2019 | CAS: 2495-35-4

Benzyl acrylate(cas: 2495-35-4) is a reagent that can be used in the preparation of 2-(Phosphonomethyl)pentanedioic Acid, a selective glutamate carboxypeptidase 2 (GCP-II) inhibitor. It can also be used in the preparation of high refractive index polyacrylates.Name: Benzyl acrylate

The author of 《Rhodium catalyzed template-assisted distal para-C-H olefination》 were Dutta, Uttam; Maiti, Sudip; Pimparkar, Sandeep; Maiti, Siddhartha; Gahan, Lawrence R.; Krenske, Elizabeth H.; Lupton, David W.; Maiti, Debabrata. And the article was published in Chemical Science in 2019. Name: Benzyl acrylate The author mentioned the following in the article:

Rhodium catalysis were extensively used for ortho-C-H functionalization reactions, and successfully extended to meta-C-H functionalization. Its application to para-C-H activation remained an unmet challenge. Herein The first example of such a reaction, with the Rh-catalyzed para-C-H olefination of arenes was disclosed to obtained para-olefinated arenes e.g., I. The use of a Si-linked cyanobiphenyl unit as a traceless directing group leads to highly para-selective arene-olefin couplings. In the experiment, the researchers used Benzyl acrylate(cas: 2495-35-4Name: Benzyl acrylate)

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Liu, Ze-Shui’s team published research in Nature Catalysis in 2020 | CAS: 2495-35-4

《Construction of axial chirality via palladium/chiral norbornene cooperative catalysis》 was published in Nature Catalysis in 2020. These research results belong to Liu, Ze-Shui; Hua, Yu; Gao, Qianwen; Ma, Yuanyuan; Tang, Hua; Shang, Yong; Cheng, Hong-Gang; Zhou, Qianghui. Name: Benzyl acrylate The article mentions the following:

Herein, a general and modular platform technol. for the construction of axial chirality via palladium/chiral norbornene cooperative catalysis I (R = Me, Et) was reported. It is a three-component cascade process that involves widely available aryl iodides R1I (R1 = 2-methylphenyl, 5,6,7,8-tetrahydronaphthalen-1-yl, pyren-1-yl, 2-methoxypyridin-3-yl, etc.), 2,6-substituted aryl bromides 2-R2-3-R3-4-R4-5-R5-6-R6-C6Br [R2 = Cl, (tert-butoxy)carbonyl, (pyrrolidin-1-yl)carbonyl, etc.; R3 = H; R4 = H, Cl, Me; R5 = H, Me; R6 = Me, cyclohexanecarbonyl, benzoyl, etc.; R2R3 = -CH=CH-CH=CH-] and olefins such as t-Bu acrylate, styrene, (triisopropylsilyl)acetylene, methylboronic acid, etc. as the reactants. A wide variety of substrates bearing an assortment of functional groups (88 examples) is compatible with this method. Other features include a distinct stereoinduction model, excellent enantioselectivities, step economy and scalability. This method is also amenable for the synthesis of chiral fluorenols II [R7 = Me, Cl; R8 = H; R7R8 = -CH=CH-CH=CH-; R9 = Me, Et, t-Bu, cyclopropyl, cyclohexyl, Ph; R10 = H, F, NO2, Br, methoxycarbonyl, N-methylcarbamoyl; R11 = H, Cl, methoxycarbonyl; R12 = Me, Et, F, OMe, OBn, [(tert-butyldimethylsilyl)oxy]methyl; R11R12 = -CH=CH-CH=CH-] and (R)-13-methyl-13H-benzo[6,7]indeno[2,1-a]pyren-13-ol, etc. through axial-to-central chirality transfer in high stereochem. fidelity. It was anticipated that this work will have broad synthetic utilities in chiral ligands and catalyst-design for asym. catalysis. In the experiment, the researchers used Benzyl acrylate(cas: 2495-35-4Name: Benzyl acrylate)

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Yan, Kelu’s team published research in Tetrahedron Letters in 2022 | CAS: 2495-35-4

Yan, Kelu; Liu, Xiao; Liu, Min; Wen, Jiangwei; Du, Mingyue; Fu, Yingxue; Chen, Wenxin published an article in 2022. The article was titled 《Iridium-catalyzed oxidative coupling and cyclization of NH isoquinolones with olefins leading to isoindolo[2,1-b]isoquinolin-5(7H)-one derivatives》, and you may find the article in Tetrahedron Letters.Reference of Benzyl acrylate The information in the text is summarized as follows:

The iridium-catalyzed oxidative coupling and cyclization of NH isoquinolones with olefins had been realized. Most isoindolo[2,1-b]isoquinolin-5(7H)-one derivatives I [R1 = H, 2-Et, 3-Me, etc.; R2 = H, 10-Me, 9-Br, etc.; R3 = Ph, 4-MeC6H4, 4-MeOC6H4, etc.; R4 = CO2Me, CO2Et, CO2Bn, etc.] were obtained in moderate to good yields. Several derivatization reactions including functional group conversion and further C-H/olefin coupling were also performed. This transformation realized the less developed Cp*Ir(III) catalyzed coupling and cyclization reaction of NH substrates with olefins. The experimental process involved the reaction of Benzyl acrylate(cas: 2495-35-4Reference of Benzyl acrylate)

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Xi, Xiaoxiang’s team published research in Organic Letters in 2022 | CAS: 2495-35-4

In 2022,Xi, Xiaoxiang; Chen, Yukun; Yuan, Weiming published an article in Organic Letters. The title of the article was 《Nickel-Catalyzed Three-Component Alkylacylation of Alkenes Enabled by a Photoactive Electron Donor-Acceptor Complex》.Synthetic Route of C10H10O2 The author mentioned the following in the article:

An electron donor-acceptor complex-enabled, nickel-catalyzed three-component net-reductive 1,2-alkylacylation of alkenes is developed. This conjunctive reductive acyl cross-coupling process obviates the use of an exogenous photocatalyst and a stoichiometric metal-based reductant, affording various synthetically useful 1,3-dicarbonyl compounds in good yields with a broad substrate scope and excellent functional group tolerance. Both alkyl and acyl electrophiles are derived from the highly abundant and readily accessible carboxylic acids, making the catalytic 1,2-dicarbofunctionalization more synthetically general and sustainable. In the part of experimental materials, we found many familiar compounds, such as Benzyl acrylate(cas: 2495-35-4Synthetic Route of C10H10O2)

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Kumar, Pravin’s team published research in Organic Letters in 2019 | CAS: 2495-35-4

Formula: C10H10O2In 2019 ,《Catalyst Control in Positional-Selective C-H Alkenylation of Isoxazoles and a Ruthenium-Mediated Assembly of Trisubstituted Pyrroles》 appeared in Organic Letters. The author of the article were Kumar, Pravin; Kapur, Manmohan. The article conveys some information:

High levels of catalyst control are demonstrated in determining the positional selectivity in C-H alkenylation of isoxazoles. A cationic rhodium-mediated, strong-directing group promotes C(sp2)-H activation at the proximal aryl ring whereas, the palladium-mediated electrophilic metalation leads to the C(sp2)-H activation at the distal position of the directing group. Synthetic elaboration of this C-H alkenylation product via ruthenium and copper co-catalysis leads to an efficient method for the assembly of densely substituted pyrroles.Benzyl acrylate(cas: 2495-35-4Formula: C10H10O2) was used in this study.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Agasti, Soumitra’s team published research in ACS Catalysis in 2019 | CAS: 2495-35-4

In 2019,ACS Catalysis included an article by Agasti, Soumitra; Mondal, Bhaskar; Achar, Tapas Kumar; Sinha, Soumya Kumar; Sarala Suseelan, Anjana; Szabo, Kalman J.; Schoenebeck, Franziska; Maiti, Debabrata. Synthetic Route of C10H10O2. The article was titled 《Orthogonal Selectivity in C-H Olefination: Synthesis of Branched Vinylarene with Unactivated Aliphatic Substitution》. The information in the text is summarized as follows:

Oxidative coupling is a useful tool to synthesize vinylarenes. Despite remarkable successes in linear vinylarene, branched vinylarene synthesis has remained underdeveloped. Overcoming this limitation, herein, we report a chelation-assisted oxidative coupling to generate branched olefinated product in high yield. Exclusive branched selectivity was obtained using alkenyl carboxylic acid. Detailed exptl. studies combined with computational investigations suggest that β-migratory insertion, followed by a decarboxylation pathway is operative for the overall transformation. The experimental process involved the reaction of Benzyl acrylate(cas: 2495-35-4Synthetic Route of C10H10O2)

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Guan, Zhipeng’s team published research in Chemical Science in 2022 | CAS: 2495-35-4

In 2022,Guan, Zhipeng; Zhong, Xingxing; Ye, Yayu; Li, Xiangwei; Cong, Hengjiang; Yi, Hong; Zhang, Heng; Huang, Zhiliang; Lei, Aiwen published an article in Chemical Science. The title of the article was 《Selective radical cascade (4+2) annulation with olefins towards the synthesis of chroman derivatives via organo-photoredox catalysis》.Reference of Benzyl acrylate The author mentioned the following in the article:

Here a new (4 + 2) radical annulation approach for the construction of these functional six-membered frameworks I (R = ethoxycarbonyl, N-methyl-N-phenylcarbamoyl, benzenesulfonyl, (2,2,6,6-tetramethylpiperidin-1-yl)carbonyl, etc.; R1 = H, Me, methoxycarbonyl; R2 = H, Me, OMe; R3 = H, F, Ph, 2,2-dichlorocyclopropyl, etc.; R2R3 = -CH=CH-CH=CH-; R4 = H, Me, OMe, CF3; R5 = H, Me;) via photocatalysis was reported. Featuring mild reaction conditions, the protocol allows readily available N-hydroxyphthalimide esters II and electron-deficient olefins RCH=CHR1 to be converted into a wide range of valuable chromans I in a highly selective manner. Moreover, the present strategy can be used in the late-stage functionalization of natural product derivatives and biol. active compounds, which demonstrated the potential application. This method is complementary to the traditional Diels-Alder [4 + 2] cycloaddition reaction of ortho-quinone methides II and electron-rich dienophiles, since electron-deficient dienophiles were smoothly transformed into the desired chromans I. After reading the article, we found that the author used Benzyl acrylate(cas: 2495-35-4Reference of Benzyl acrylate)

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Das, Jayabrata’s team published research in Chemical Science in 2020 | CAS: 2495-35-4

《A direct route to six and seven membered lactones via γ-C(sp3)-H activation: a simple protocol to build molecular complexity》 was written by Das, Jayabrata; Dolui, Pravas; Ali, Wajid; Biswas, Jyoti Prasad; Chandrashekar, Hediyala B.; Prakash, Gaurav; Maiti, Debabrata. Name: Benzyl acrylate And the article was included in Chemical Science in 2020. The article conveys some information:

Lactones comprise a class of valuable compounds having biol. as well as industrial importance. Development of a methodol. to synthesize such mols. directly from readily available materials such as aliphatic carboxylic acid is highly desirable. Herein, synthesis of δ-lactones I (R1 = Me, R2 = Me, Et, n-Pr, n-Bu; R1 = Et, R2 = Et, i-Pr; R = MeO2C, CN, MeSO2, etc.) and ε-lactones II (R1 = R2 = Me; R’ = Me, Et, Ph, etc.) via selective γ-C(sp3)-H activation is reported. The γ-C-H bond-containing aliphatic carboxylic acids R1R2CMeCH2CO2H provide six- or seven-membered lactones depending on the olefin partner (alkene RCH:CH2 or N-R’-maleimide, resp.) in the presence of a palladium catalyst. A mechanistic investigation suggests that C-H activation is the rate-determining step. Further transformations of the lactones have been carried out to showcase the applicability of the present strategy. The experimental part of the paper was very detailed, including the reaction process of Benzyl acrylate(cas: 2495-35-4Name: Benzyl acrylate)

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Srinivas, Dasari’s team published research in Organic Letters in 2021 | CAS: 2495-35-4

Srinivas, Dasari; Satyanarayana, Gedu published their research in Organic Letters in 2021. The article was titled 《Palladium Catalyzed Distal meta-C-H Functionalization of Arylacetic Acid Derivatives》.Safety of Benzyl acrylate The article contains the following contents:

Herein, meta-C-H olefination of phenylacetic acid derivatives I [R1 = R2 = Me, Et; R1 = H, R2 = Me; R1R2 = (CH2)4; R3 = H, 3-Me, 4-MeO, 4-Br, 3,4-Cl2, etc.] with alkenes R4CH:CHR5 (R4 = H, R5 = MeO2C, EtO2C, Me2NCO, MeSO2, 4-O2NC6H4, etc.; R4 = R5 = EtO2C; etc.) for the synthesis of arylacrylates and analogs II by tethering with a simple nitrile-based template through palladium catalysis has been presented. Notably, the versatility of the method has been evaluated with a wide range of phenylacetic acid derivatives for accomplishing the meta-olefination products in fair to excellent yields with outstanding selectivities under milder conditions. Significantly, the present strategy was successfully exemplified for the synthesis of drugs/natural product analogs, such as naproxen, ibuprofen, paracetamol, and cholesterol. The experimental process involved the reaction of Benzyl acrylate(cas: 2495-35-4Safety of Benzyl acrylate)

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics