Adamczyk, Maciej; Johnson, Donald D.; Reddy, Rajarathnam E. published an article in Tetrahedron. The title of the article was 《Collagen crosslinks: synthesis of pyridinoline, deoxypyridinoline and their analogs》.HPLC of Formula: 220243-81-2 The author mentioned the following in the article:
An efficient chiral synthesis of I (Boc = Me3CO2C), a key intermediate for the preparation of collagen crosslinks pyridinoline (II; R = OH) and deoxypyridinoline (II; R = H) was achieved from Boc-Glu-OCMe3. Quaternization of I with iodide (5R)-III (R = OH) followed by hydrolysis provided a first chiral synthesis of natural (2R)-(+)-II (R = OH). (2S)-(+)-II (R = OH) was also synthesized from I and iodide (5S)-III (R = OH). Similarly, quaternization of I with iodide III (R = H), which was prepared from Boc-Lys-OH in three steps, followed by hydrolysis afforded natural II (R = H) in 5.3% overall yield. Also, the synthesis of racemic (±)-II (R = H) and a variety of its analogs is presented. After reading the article, we found that the author used tert-Butyl 2-((tert-butoxycarbonyl)amino)-6-hydroxyhexanoate(cas: 220243-81-2HPLC of Formula: 220243-81-2)
tert-Butyl 2-((tert-butoxycarbonyl)amino)-6-hydroxyhexanoate(cas: 220243-81-2) belongs to esters. They are important in biology, being one of the main classes of lipids and comprising the bulk of animal fats and vegetable oils.Esters typically have a pleasant smell; those of low molecular weight are commonly used as fragrances and are found in essential oils and pheromones.HPLC of Formula: 220243-81-2
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics