Category: 2065-23-8

These common heterocyclic compound, 2065-23-8, name is Methyl 2-phenoxyacetate, its traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc, below Introduce a new synthetic route. category: esters-buliding-blocks

8.3 g of compound 2 was dissolved in 100 mL of methanol/water (9:1).12 g of lithium hydroxide was added. The reaction system was heated to 50 C and stirred for 12 h.The reaction was followed by TLC. After the reaction was over, the reaction system was added to 300 mL of ice water.Then, pH = 1 was adjusted with 6 mol/L HCl, and a large amount of white solid was formed. filter,A white solid was collected and dried in vacuo to give 6.8 g of white solid. The yield was 90%.

The synthetic route of Methyl 2-phenoxyacetate has been constantly updated, and we look forward to future research findings.

Reference:
Patent; Liaocheng University; Lei Kang; Chen Ke; Wang Shiben; Hua Xuewen; Liu Yang; Xu Xiaohua; (8 pag.)CN108570028; (2018); A;,
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

2065-23-8, name is Methyl 2-phenoxyacetate, belongs to esters-buliding-blocks compound, is considered to be a conventional heterocyclic compound, which is widely used in drug synthesis. The chemical synthesis route is as follows. name: Methyl 2-phenoxyacetate

To a solution of 55 mg (1.00 mmol) of propargyl amine (2), in dry MTBE (2 mL) in a screwcapSchlenk vessel, were added 1.5 mmol of the methyl ester 1 (for experimental details seeTable 1) and Novozyme 435 (50 % w/w of corresponding ester substrate used) and thereaction was shaken in an incubating shaker at 45 C for 4 or 24 h (depending upon the natureof ester used). After the reaction time, the enzyme beads were filtered off and the filtrate wassubjected to column chromatography on silica gel (n-hexane/ethylacetate 1:1 or 2:1) to obtainthe pure product 3.

The synthetic route of 2065-23-8 has been constantly updated, and we look forward to future research findings.

Reference:
Article; Hassan, Sidra; Tschersich, Roxanne; Mueller, Thomas J.J.; Tetrahedron Letters; vol. 54; 35; (2013); p. 4641 – 4644;,
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 2065-23-8, name is Methyl 2-phenoxyacetate, This compound has unique chemical properties. The synthetic route is as follows., HPLC of Formula: C9H10O3

167.87 g of 99% methyl phenoxyacetate (1 mol) was sequentially added to a 500 mL four-necked flask.1.26 g of 99% zinc chloride and 1.68 g of 99% 4,5-dimethylisothiazole,154.69g of 99% chlorine (2.16 mol) was introduced at -20 C.After the heat preservation reaction for 30 minutes,Distilled at a pressure of 1 kPa and collected at 140-150 CDivided, 236.21g of methyl 2,4-dichlorophenoxyacetate,content98.8%,The yield was 99.28% based on methyl phenoxyacetate.

According to the analysis of related databases, 2065-23-8, the application of this compound in the production field has become more and more popular.

Reference:
Patent; Shandong Runbo Biological Technology Co., Ltd.; Sun Guoqing; Hou Yongsheng; Zhang Liguo; Chi Zhilong; Hu Yishan; (12 pag.)CN108947815; (2018); A;,
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Related Products of 2065-23-8, These common heterocyclic compound, 2065-23-8, name is Methyl 2-phenoxyacetate, its traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc, below Introduce a new synthetic route.

To the methyl phenoxyacetate obtained by distillation, 1.72 g of tin tetrachloride having a purity of 99% and 0.60 g of 2,5-dichlorothiazole having a purity of 99% were added.279.41 g of 99% pure sulfuryl chloride was added at 60 C to react.After the addition, the reaction was kept at this temperature for 0.5 h.Distilling at a pressure of 1 kPa and collecting fractions at 115-125 C,234.12 g of methyl 2,4-dichlorophenoxyacetate was obtained, and the content was 99.18%.

Statistics shows that Methyl 2-phenoxyacetate is playing an increasingly important role. we look forward to future research findings about 2065-23-8.

Reference:
Patent; Shandong Runbo Biological Technology Co., Ltd.; Sun Guoqing; Hou Yongsheng; Chi Zhilong; Zhang Liguo; Hu Yishan; (15 pag.)CN108947822; (2018); A;,
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Synthetic Route of 2065-23-8, The chemical industry reduces the impact on the environment during synthesis 2065-23-8, name is Methyl 2-phenoxyacetate, I believe this compound will play a more active role in future production and life.

167.87 g of 99% methyl phenoxyacetate (1 mol), 1.26 g of 99% zinc chloride and 1.68 g of 99% were sequentially added to a 500 mL four-necked flask.2,5-dichlorothiazole, 154.69 g of 99% chlorine (2.16 mol) was introduced at -20 C.After the heat preservation reaction for 30 minutes,Distilling and collecting fractions of 140-150 C under a pressure of 1 kpa,Methyl 2,4-dichlorophenoxyacetate236.21g, content 98.8%,The yield was 99.28% based on methyl phenoxyacetate.

In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles, Methyl 2-phenoxyacetate, other downstream synthetic routes, hurry up and to see.

Reference:
Patent; Shandong Runbo Biological Technology Co., Ltd.; Sun Guoqing; Hou Yongsheng; Zhang Liguo; Chi Zhilong; Hu Yishan; (12 pag.)CN108947807; (2018); A;,
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

These common heterocyclic compound, 2065-23-8, name is Methyl 2-phenoxyacetate, its traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc, below Introduce a new synthetic route. Recommanded Product: Methyl 2-phenoxyacetate

8.3 g of compound 2 was dissolved in 100 mL of methanol/water (9:1).12 g of lithium hydroxide was added. The reaction system was heated to 50 C and stirred for 12 h.The reaction was followed by TLC. After the reaction was over, the reaction system was added to 300 mL of ice water.Then, pH = 1 was adjusted with 6 mol/L HCl, and a large amount of white solid was formed. filter,A white solid was collected and dried in vacuo to give 6.8 g of white solid. The yield was 90%.

The synthetic route of Methyl 2-phenoxyacetate has been constantly updated, and we look forward to future research findings.

Reference:
Patent; Liaocheng University; Lei Kang; Chen Ke; Wang Shiben; Hua Xuewen; Liu Yang; Xu Xiaohua; (8 pag.)CN108570028; (2018); A;,
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 2065-23-8, name is Methyl 2-phenoxyacetate, This compound has unique chemical properties. The synthetic route is as follows., Computed Properties of C9H10O3

167.87 g of 99% methyl phenoxyacetate (1 mol) was sequentially added to a 500 mL four-necked flask.1.26 g of 99% zinc chloride and 1.68 g of 99% 4,5-dimethylisothiazole,154.69g of 99% chlorine (2.16 mol) was introduced at -20 C.After the heat preservation reaction for 30 minutes,Distilled at a pressure of 1 kPa and collected at 140-150 CDivided, 236.21g of methyl 2,4-dichlorophenoxyacetate,content98.8%,The yield was 99.28% based on methyl phenoxyacetate.

According to the analysis of related databases, 2065-23-8, the application of this compound in the production field has become more and more popular.

Reference:
Patent; Shandong Runbo Biological Technology Co., Ltd.; Sun Guoqing; Hou Yongsheng; Zhang Liguo; Chi Zhilong; Hu Yishan; (12 pag.)CN108947815; (2018); A;,
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

2065-23-8, name is Methyl 2-phenoxyacetate, belongs to esters-buliding-blocks compound, is considered to be a conventional heterocyclic compound, which is widely used in drug synthesis. The chemical synthesis route is as follows. Recommanded Product: Methyl 2-phenoxyacetate

To a solution of 55 mg (1.00 mmol) of propargyl amine (2), in dry MTBE (2 mL) in a screwcapSchlenk vessel, were added 1.5 mmol of the methyl ester 1 (for experimental details seeTable 1) and Novozyme 435 (50 % w/w of corresponding ester substrate used) and thereaction was shaken in an incubating shaker at 45 C for 4 or 24 h (depending upon the natureof ester used). After the reaction time, the enzyme beads were filtered off and the filtrate wassubjected to column chromatography on silica gel (n-hexane/ethylacetate 1:1 or 2:1) to obtainthe pure product 3.

The synthetic route of 2065-23-8 has been constantly updated, and we look forward to future research findings.

Reference:
Article; Hassan, Sidra; Tschersich, Roxanne; Mueller, Thomas J.J.; Tetrahedron Letters; vol. 54; 35; (2013); p. 4641 – 4644;,
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Application of 2065-23-8, The chemical industry reduces the impact on the environment during synthesis 2065-23-8, name is Methyl 2-phenoxyacetate, I believe this compound will play a more active role in future production and life.

167.87 g of 99% methyl phenoxyacetate (1 mol), 1.26 g of 99% zinc chloride and 1.68 g of 99% 2,4,6-trimethyldiphenyl sulfide were successively added to a 500 mL four-necked flask.154.69g of 99% chlorine gas (2.16mol) was introduced at -20 C, and the reaction was allowed to stand for 30 min, and the fraction of 140-150 C was distilled under a pressure of 1 kpa to obtain methyl 2,4-dichlorophenoxyacetate. 236.21 g, content 98.8%, yield 99.28% based on methyl phenoxyacetate.

In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles, Methyl 2-phenoxyacetate, other downstream synthetic routes, hurry up and to see.

Reference:
Patent; Shandong Runbo Biological Technology Co., Ltd.; Sun Guoqing; Hou Yongsheng; Zhang Liguo; Chi Zhilong; Hu Yishan; (14 pag.)CN108947821; (2018); A;,
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

These common heterocyclic compound, 2065-23-8, name is Methyl 2-phenoxyacetate, its traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc, below Introduce a new synthetic route. SDS of cas: 2065-23-8

To the methyl phenoxyacetate obtained by distillation,0.09 g of 99% pure lead acetate and 1.29 g of 99% pure 2,3,4-trichlorothiophene were added.118.34 g of 99% pure thionyl chloride was added dropwise at 20 C to react.After the addition, the reaction was kept at this temperature for 0.5 h.The fraction was distilled at a pressure of 1 kPa and collected at 110 to 120 C to obtain 200.87 g of methyl 4-chlorophenoxyacetate, and the content was 98.84%.

The synthetic route of Methyl 2-phenoxyacetate has been constantly updated, and we look forward to future research findings.

Reference:
Patent; Shandong Runbo Biological Technology Co., Ltd.; Sun Guoqing; Hou Yongsheng; Chi Zhilong; Zhang Liguo; Hu Yishan; (13 pag.)CN108947839; (2018); A;,
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics