Zauer, E. A. et al. published their research in Chemistry of Heterocyclic Compounds (New York, NY, United States) in 2011 | CAS: 19432-68-9

Methyl 2-thienylacetate (cas: 19432-68-9) belongs to esters. Volatile esters with characteristic odours are used in synthetic flavours, perfumes, and cosmetics. Certain volatile esters are used as solvents for lacquers, paints, and varnishes. Esters are more polar than ethers but less polar than alcohols. They participate in hydrogen bonds as hydrogen-bond acceptors, but cannot act as hydrogen-bond donors, unlike their parent alcohols. This ability to participate in hydrogen bonding confers some water-solubility.Formula: C7H8O2S

Enthalpy of formation of thiophene derivatives was written by Zauer, E. A.. And the article was included in Chemistry of Heterocyclic Compounds (New York, NY, United States) in 2011.Formula: C7H8O2S This article mentions the following:

The enthalpy of formation in the gas phase has been calculated for 21 carbonyl compounds of the thiophene series with the aid of the PM3, MINDO, AM1, and MNDO semiempirical quantum-chem. methods. Comparison of them with exptl. data showed that the best linear correlation was achieved with the PM3 method. The latter in conjunction with a developed linear regression equation has been used to predict the enthalpy of formation of 22 carboxylic acids and ketones of the thiophene series. In the experiment, the researchers used many compounds, for example, Methyl 2-thienylacetate (cas: 19432-68-9Formula: C7H8O2S).

Methyl 2-thienylacetate (cas: 19432-68-9) belongs to esters. Volatile esters with characteristic odours are used in synthetic flavours, perfumes, and cosmetics. Certain volatile esters are used as solvents for lacquers, paints, and varnishes. Esters are more polar than ethers but less polar than alcohols. They participate in hydrogen bonds as hydrogen-bond acceptors, but cannot act as hydrogen-bond donors, unlike their parent alcohols. This ability to participate in hydrogen bonding confers some water-solubility.Formula: C7H8O2S

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Zhang, Junlin et al. published their research in Zhongguo Yiyao Gongye Zazhi in 1993 | CAS: 19432-68-9

Methyl 2-thienylacetate (cas: 19432-68-9) belongs to esters. Esters perform as high-grade solvents for a broad array of plastics, plasticizers, resins, and lacquers, and are one of the largest classes of synthetic lubricants on the commercial market. Many esters have the potential for conformational isomerism, but they tend to adopt an s-cis (or Z) conformation rather than the s-trans (or E) alternative, due to a combination of hyperconjugation and dipole minimization effects. The preference for the Z conformation is influenced by the nature of the substituents and solvent, if present. Lactones with small rings are restricted to the s-trans (i.e. E) conformation due to their cyclic structure.Name: Methyl 2-thienylacetate

Synthesis of 2-thiopheneacetic acid was written by Zhang, Junlin;Cheng, Hui;Qian, Yuejun. And the article was included in Zhongguo Yiyao Gongye Zazhi in 1993.Name: Methyl 2-thienylacetate This article mentions the following:

Treatment of 2-acetylthiophene with BF3.OEt2 and Pb(OAc)4 in MeOH gave 74% Me 2-thiopheneacetate, hydrolysis of which with aqueous NaOH gave 95.7% the title compound In the experiment, the researchers used many compounds, for example, Methyl 2-thienylacetate (cas: 19432-68-9Name: Methyl 2-thienylacetate).

Methyl 2-thienylacetate (cas: 19432-68-9) belongs to esters. Esters perform as high-grade solvents for a broad array of plastics, plasticizers, resins, and lacquers, and are one of the largest classes of synthetic lubricants on the commercial market. Many esters have the potential for conformational isomerism, but they tend to adopt an s-cis (or Z) conformation rather than the s-trans (or E) alternative, due to a combination of hyperconjugation and dipole minimization effects. The preference for the Z conformation is influenced by the nature of the substituents and solvent, if present. Lactones with small rings are restricted to the s-trans (i.e. E) conformation due to their cyclic structure.Name: Methyl 2-thienylacetate

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Temprado, Manuel et al. published their research in Thermochimica Acta in 2006 | CAS: 19432-68-9

Methyl 2-thienylacetate (cas: 19432-68-9) belongs to esters. Carboxylic acid esters of low molecular weight are colourless, volatile liquids with pleasant odours, slightly soluble in water. Cyclic esters are called lactones, regardless of whether they are derived from an organic or inorganic acid. One example of an organic lactone is 绾?valerolactone.Category: esters-buliding-blocks

Thermophysical properties of sulfur heterocycles: Thiane and thiophene derivatives was written by Temprado, Manuel;Roux, Maria Victoria;Jimenez, Pilar;Guzman-Mejia, Ramon;Juaristi, Eusebio. And the article was included in Thermochimica Acta in 2006.Category: esters-buliding-blocks This article mentions the following:

The present study reports a DSC study of the sulfur heterocyclic compounds: 2,2′-bithiophene [492-97-7]; 2,5-thiophenedicarboxylic acid [4282-31-9]; 3-acetylthiophene [1468-83-3]; 2-thiopheneacetic acid [1918-77-0]; 3-thiopheneacetic acid [6964-21-2]; 1,4-dithiane sulfone [139408-38-1]; 1,3-oxathiane-3,3-dioxide (1,3-oxathiane sulfone) [109577-03-9], and 1,4-oxathiane-4,4-dioxide (1,4-oxathiane sulfone) [107-61-9] in the temperature interval T = 268 K and the melting temperatures Temperatures, enthalpies, and entropies of fusion are reported. 1,4-Oxathiane sulfone presents solid-solid phase transitions near fusion. No addnl. solid-solid phase transitions were observed for the other solid compounds For the compounds that are solids over the temperature interval, the heat capacity of the condensed phase was measured. Heat capacities at T = 298.15 K for the liquids 2-acetylthiophene [88-15-3]; Me, 2-thiopheneacetate [19432-68-9]; Me, 3-thiopheneacetate [58414-52-1], and thiazole [288-47-1] were also measured. The Cp,m (298.15 K) values obtained in this work were compared with the available exptl. data and with values estimated with group contribution schemes. In the experiment, the researchers used many compounds, for example, Methyl 2-thienylacetate (cas: 19432-68-9Category: esters-buliding-blocks).

Methyl 2-thienylacetate (cas: 19432-68-9) belongs to esters. Carboxylic acid esters of low molecular weight are colourless, volatile liquids with pleasant odours, slightly soluble in water. Cyclic esters are called lactones, regardless of whether they are derived from an organic or inorganic acid. One example of an organic lactone is 绾?valerolactone.Category: esters-buliding-blocks

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Fallon, Kealan J. et al. published their research in Journal of the American Chemical Society in 2019 | CAS: 19432-68-9

Methyl 2-thienylacetate (cas: 19432-68-9) belongs to esters. Esters are widespread in nature and are widely used in industry. In nature, fats are in general triesters derived from glycerol and fatty acids. Esters are responsible for the aroma of many fruits, including apples, durians, pears, bananas, pineapples, and strawberries. Because of their lack of hydrogen-bond-donating ability, esters do not self-associate. Consequently, esters are more volatile than carboxylic acids of similar molecular weight.Quality Control of Methyl 2-thienylacetate

Exploiting excited-state aromaticity to design highly stable singlet fission materials was written by Fallon, Kealan J.;Budden, Peter;Salvadori, Enrico;Ganose, Alex M.;Savory, Christopher N.;Eyre, Lissa;Dowland, Simon;Ai, Qianxiang;Goodlett, Stephen;Risko, Chad;Scanlon, David O.;Kay, Christopher W. M.;Rao, Akshay;Friend, Richard H.;Musser, Andrew J.;Bronstein, Hugo. And the article was included in Journal of the American Chemical Society in 2019.Quality Control of Methyl 2-thienylacetate This article mentions the following:

Singlet fission, the process of forming two triplet excitons from one singlet exciton, is a characteristic reserved for only a handful of organic mols. due to the atypical energetic requirement for low energy excited triplet states. The predominant strategy for achieving such a trait is by increasing ground state diradical character; however, this greatly reduces ambient stability. Herein, we exploit Baird’s rule of excited state aromaticity to manipulate the singlet-triplet energy gap and create novel singlet fission candidates. We achieve this through the inclusion of a [4n] 5-membered heterocycle, whose electronic resonance promotes aromaticity in the triplet state, stabilizing its energy relative to the singlet excited state. Using this theory, we design a family of derivatives of indolonaphthyridine thiophene (INDT) with highly tunable excited state energies. Not only do we access novel singlet fission materials, they also exhibit excellent ambient stability, imparted due to the delocalized nature of the triplet excited state. Spin-coated films retained up to 85% activity after several weeks of exposure to oxygen and light, while analogous films of TIPS-pentacene showed full degradation after 4 days, showcasing the excellent stability of this class of singlet fission scaffold. Extension of our theor. anal. to almost ten thousand candidates reveals an unprecedented degree of tunability and several thousand potential fission-capable candidates, while clearly demonstrating the relationship between triplet aromaticity and singlet-triplet energy gap, confirming this novel strategy for manipulating the exchange energy in organic materials. In the experiment, the researchers used many compounds, for example, Methyl 2-thienylacetate (cas: 19432-68-9Quality Control of Methyl 2-thienylacetate).

Methyl 2-thienylacetate (cas: 19432-68-9) belongs to esters. Esters are widespread in nature and are widely used in industry. In nature, fats are in general triesters derived from glycerol and fatty acids. Esters are responsible for the aroma of many fruits, including apples, durians, pears, bananas, pineapples, and strawberries. Because of their lack of hydrogen-bond-donating ability, esters do not self-associate. Consequently, esters are more volatile than carboxylic acids of similar molecular weight.Quality Control of Methyl 2-thienylacetate

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Kraevaya, Olga A. et al. published their research in Organic Letters in 2021 | CAS: 19432-68-9

Methyl 2-thienylacetate (cas: 19432-68-9) belongs to esters. Esters perform as high-grade solvents for a broad array of plastics, plasticizers, resins, and lacquers, and are one of the largest classes of synthetic lubricants on the commercial market. Polyesters are important plastics, with monomers linked by ester moieties. Esters contain a carbonyl center, which gives rise to 120鎺?C閳ユ弲閳ユ彊 and O閳ユ弲閳ユ彊 angles. Unlike amides, esters are structurally flexible functional groups because rotation about the C閳ユ彊閳ユ弲 bonds has a low barrier. Their flexibility and low polarity is manifested in their physical properties; they tend to be less rigid (lower melting point) and more volatile (lower boiling point) than the corresponding amides. Category: esters-buliding-blocks

Water-Promoted Reaction of C60Ar5Cl Compounds with Thiophenes Delivers a Family of Multifunctional Fullerene Derivatives with Selective Antiviral Properties was written by Kraevaya, Olga A.;Bolshakova, Valeriya S.;Peregudov, Alexander S.;Chernyak, Alexander V.;Slesarenko, Nikita A.;Markov, Vitaliy Yu.;Lukonina, Natalia S.;Martynenko, Vyacheslav M.;Sinegubova, Ekaterina O.;Shestakov, Alexander F.;Zarubaev, Vladimir V.;Schols, Dominique;Troshin, Pavel A.. And the article was included in Organic Letters in 2021.Category: esters-buliding-blocks This article mentions the following:

A reaction of the fullerene derivatives C60Ar5Cl was reported, which enabled the substitution of Cl with thiophene residues and the formation of the family of C1-sym. C60 fullerene derivatives with six functional addends C60Ar5Th. The discovered reaction provided a straightforward approach to the synthesis of previously inaccessible multifunctional water-soluble fullerene derivatives, including the compounds with antiviral activity against human immunodeficiency and influenza viruses. In the experiment, the researchers used many compounds, for example, Methyl 2-thienylacetate (cas: 19432-68-9Category: esters-buliding-blocks).

Methyl 2-thienylacetate (cas: 19432-68-9) belongs to esters. Esters perform as high-grade solvents for a broad array of plastics, plasticizers, resins, and lacquers, and are one of the largest classes of synthetic lubricants on the commercial market. Polyesters are important plastics, with monomers linked by ester moieties. Esters contain a carbonyl center, which gives rise to 120鎺?C閳ユ弲閳ユ彊 and O閳ユ弲閳ユ彊 angles. Unlike amides, esters are structurally flexible functional groups because rotation about the C閳ユ彊閳ユ弲 bonds has a low barrier. Their flexibility and low polarity is manifested in their physical properties; they tend to be less rigid (lower melting point) and more volatile (lower boiling point) than the corresponding amides. Category: esters-buliding-blocks

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Zhu, Yaoqiu et al. published their research in ACS Medicinal Chemistry Letters in 2013 | CAS: 19432-68-9

Methyl 2-thienylacetate (cas: 19432-68-9) belongs to esters. Esters typically have a pleasant smell; those of low molecular weight are commonly used as fragrances and are found in essential oils and pheromones. Cyclic esters are called lactones, regardless of whether they are derived from an organic or inorganic acid. One example of an organic lactone is 绾?valerolactone.Electric Literature of C7H8O2S

Deuterated Clopidogrel Analogues as a New Generation of Antiplatelet Agents was written by Zhu, Yaoqiu;Zhou, Jiang;Jiao, Bo. And the article was included in ACS Medicinal Chemistry Letters in 2013.Electric Literature of C7H8O2S This article mentions the following:

Clopidogrel (CPG) is an antithrombotic prodrug that needs hepatic cytochrome P 450 (CYP) enzymes for its bioactivation. The clin. effects of CPG have been associated with high intersubject variability and a certain level of resistance. Recently, comprehensive biotransformation studies of CPG support that the observed clin. uncertainty stems from the low bioactivation efficiency, which is attributed to extensive attritional metabolism (e.g., hydrolysis of the Me ester functionality and oxidation of the piperidine moiety). With the goal of potentiating the desired thiophene 2-oxidation through minimal structural modification, we have adopted the strategy of targeted metabolism shift and have designed and synthesized deuterated piperidine analogs of CPG. In vitro studies showed that the prodrug activation percentages have been significantly increased for the deuterated analogs as a result of stability enhancement of the piperidine moiety. In a pharmacol. study with a rat model, oral administration of the deuterated analogs also demonstrated higher inhibitory activity than that of CPG against ADP (ADP) induced platelet aggregation. These deuterated analogs represent a new generation of antiplatelet agents with the potential to overcome the major clin. drawbacks of CPG. In the experiment, the researchers used many compounds, for example, Methyl 2-thienylacetate (cas: 19432-68-9Electric Literature of C7H8O2S).

Methyl 2-thienylacetate (cas: 19432-68-9) belongs to esters. Esters typically have a pleasant smell; those of low molecular weight are commonly used as fragrances and are found in essential oils and pheromones. Cyclic esters are called lactones, regardless of whether they are derived from an organic or inorganic acid. One example of an organic lactone is 绾?valerolactone.Electric Literature of C7H8O2S

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Monjas, Leticia et al. published their research in ChemMedChem in 2017 | CAS: 19432-68-9

Methyl 2-thienylacetate (cas: 19432-68-9) belongs to esters. Esters typically have a pleasant smell; those of low molecular weight are commonly used as fragrances and are found in essential oils and pheromones. Many esters have the potential for conformational isomerism, but they tend to adopt an s-cis (or Z) conformation rather than the s-trans (or E) alternative, due to a combination of hyperconjugation and dipole minimization effects. The preference for the Z conformation is influenced by the nature of the substituents and solvent, if present. Lactones with small rings are restricted to the s-trans (i.e. E) conformation due to their cyclic structure.Reference of 19432-68-9

Dynamic combinatorial chemistry to identify binders of ThiT, an S-component of the energy-coupling factor transporter for thiamin was written by Monjas, Leticia;Swier, Lotteke J. Y. M.;Setyawati, Inda;Slotboom, Dirk J.;Hirsch, Anna K. H.. And the article was included in ChemMedChem in 2017.Reference of 19432-68-9 This article mentions the following:

We applied dynamic combinatorial chem. (DCC) to identify ligands of ThiT, the S-component of the energy-coupling factor (ECF) transporter for thiamin in Lactococcus lactis. We used a pre-equilibrated dynamic combinatorial library (DCL) and saturation-transfer difference (STD) NMR spectroscopy to identify ligands of ThiT. This is the 1st report in which DCC has been used for fragment growing to an ill-defined pocket, and one of the 1st reports for its application with an integral membrane protein as target. In the experiment, the researchers used many compounds, for example, Methyl 2-thienylacetate (cas: 19432-68-9Reference of 19432-68-9).

Methyl 2-thienylacetate (cas: 19432-68-9) belongs to esters. Esters typically have a pleasant smell; those of low molecular weight are commonly used as fragrances and are found in essential oils and pheromones. Many esters have the potential for conformational isomerism, but they tend to adopt an s-cis (or Z) conformation rather than the s-trans (or E) alternative, due to a combination of hyperconjugation and dipole minimization effects. The preference for the Z conformation is influenced by the nature of the substituents and solvent, if present. Lactones with small rings are restricted to the s-trans (i.e. E) conformation due to their cyclic structure.Reference of 19432-68-9

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Monjas, Leticia et al. published their research in ChemMedChem in 2017 | CAS: 19432-68-9

Methyl 2-thienylacetate (cas: 19432-68-9) belongs to esters. Esters typically have a pleasant smell; those of low molecular weight are commonly used as fragrances and are found in essential oils and pheromones. Many esters have the potential for conformational isomerism, but they tend to adopt an s-cis (or Z) conformation rather than the s-trans (or E) alternative, due to a combination of hyperconjugation and dipole minimization effects. The preference for the Z conformation is influenced by the nature of the substituents and solvent, if present. Lactones with small rings are restricted to the s-trans (i.e. E) conformation due to their cyclic structure.Reference of 19432-68-9

Dynamic combinatorial chemistry to identify binders of ThiT, an S-component of the energy-coupling factor transporter for thiamin was written by Monjas, Leticia;Swier, Lotteke J. Y. M.;Setyawati, Inda;Slotboom, Dirk J.;Hirsch, Anna K. H.. And the article was included in ChemMedChem in 2017.Reference of 19432-68-9 This article mentions the following:

We applied dynamic combinatorial chem. (DCC) to identify ligands of ThiT, the S-component of the energy-coupling factor (ECF) transporter for thiamin in Lactococcus lactis. We used a pre-equilibrated dynamic combinatorial library (DCL) and saturation-transfer difference (STD) NMR spectroscopy to identify ligands of ThiT. This is the 1st report in which DCC has been used for fragment growing to an ill-defined pocket, and one of the 1st reports for its application with an integral membrane protein as target. In the experiment, the researchers used many compounds, for example, Methyl 2-thienylacetate (cas: 19432-68-9Reference of 19432-68-9).

Methyl 2-thienylacetate (cas: 19432-68-9) belongs to esters. Esters typically have a pleasant smell; those of low molecular weight are commonly used as fragrances and are found in essential oils and pheromones. Many esters have the potential for conformational isomerism, but they tend to adopt an s-cis (or Z) conformation rather than the s-trans (or E) alternative, due to a combination of hyperconjugation and dipole minimization effects. The preference for the Z conformation is influenced by the nature of the substituents and solvent, if present. Lactones with small rings are restricted to the s-trans (i.e. E) conformation due to their cyclic structure.Reference of 19432-68-9

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Monjas, Leticia et al. published their research in ChemMedChem in 2017 | CAS: 19432-68-9

Methyl 2-thienylacetate (cas: 19432-68-9) belongs to esters. Esters typically have a pleasant smell; those of low molecular weight are commonly used as fragrances and are found in essential oils and pheromones. Many esters have the potential for conformational isomerism, but they tend to adopt an s-cis (or Z) conformation rather than the s-trans (or E) alternative, due to a combination of hyperconjugation and dipole minimization effects. The preference for the Z conformation is influenced by the nature of the substituents and solvent, if present. Lactones with small rings are restricted to the s-trans (i.e. E) conformation due to their cyclic structure.Reference of 19432-68-9

Dynamic combinatorial chemistry to identify binders of ThiT, an S-component of the energy-coupling factor transporter for thiamin was written by Monjas, Leticia;Swier, Lotteke J. Y. M.;Setyawati, Inda;Slotboom, Dirk J.;Hirsch, Anna K. H.. And the article was included in ChemMedChem in 2017.Reference of 19432-68-9 This article mentions the following:

We applied dynamic combinatorial chem. (DCC) to identify ligands of ThiT, the S-component of the energy-coupling factor (ECF) transporter for thiamin in Lactococcus lactis. We used a pre-equilibrated dynamic combinatorial library (DCL) and saturation-transfer difference (STD) NMR spectroscopy to identify ligands of ThiT. This is the 1st report in which DCC has been used for fragment growing to an ill-defined pocket, and one of the 1st reports for its application with an integral membrane protein as target. In the experiment, the researchers used many compounds, for example, Methyl 2-thienylacetate (cas: 19432-68-9Reference of 19432-68-9).

Methyl 2-thienylacetate (cas: 19432-68-9) belongs to esters. Esters typically have a pleasant smell; those of low molecular weight are commonly used as fragrances and are found in essential oils and pheromones. Many esters have the potential for conformational isomerism, but they tend to adopt an s-cis (or Z) conformation rather than the s-trans (or E) alternative, due to a combination of hyperconjugation and dipole minimization effects. The preference for the Z conformation is influenced by the nature of the substituents and solvent, if present. Lactones with small rings are restricted to the s-trans (i.e. E) conformation due to their cyclic structure.Reference of 19432-68-9

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Zhang, Yangyang et al. published their research in Organic & Biomolecular Chemistry in 2021 | CAS: 19432-68-9

Methyl 2-thienylacetate (cas: 19432-68-9) belongs to esters. Volatile esters with characteristic odours are used in synthetic flavours, perfumes, and cosmetics. Certain volatile esters are used as solvents for lacquers, paints, and varnishes. Cyclic esters are called lactones, regardless of whether they are derived from an organic or inorganic acid. One example of an organic lactone is γ-valerolactone.SDS of cas: 19432-68-9

B(C6F5)3-catalyzed O-H insertion reactions of diazoalkanes with phosphinic acids was written by Zhang, Yangyang;Zhang, Xinzhi;Zhao, Jincheng;Jiang, Jun. And the article was included in Organic & Biomolecular Chemistry in 2021.SDS of cas: 19432-68-9 This article mentions the following:

A highly efficient base-, metal-, and oxidant-free catalytic O-H insertion reaction of diazoalkanes and phosphinic acids in the presence of B(C6F5)3 has been developed. This powerful methodol. provides a green approach towards the synthesis of a broad spectrum of α-phosphoryloxy carbonyl compounds with good to excellent yields (up to 99% yield). The protocol features the advantages of operational simplicity, high atom economy, practicality, easy scalability and environmental friendliness. In the experiment, the researchers used many compounds, for example, Methyl 2-thienylacetate (cas: 19432-68-9SDS of cas: 19432-68-9).

Methyl 2-thienylacetate (cas: 19432-68-9) belongs to esters. Volatile esters with characteristic odours are used in synthetic flavours, perfumes, and cosmetics. Certain volatile esters are used as solvents for lacquers, paints, and varnishes. Cyclic esters are called lactones, regardless of whether they are derived from an organic or inorganic acid. One example of an organic lactone is γ-valerolactone.SDS of cas: 19432-68-9

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics