Zhu, Jieping’s team published research in Journal of Organic Chemistry in 1995 | CAS: 169339-41-7

Methyl 2-(3-fluoro-4-nitrophenyl)acetate(cas: 169339-41-7) belongs to esters. They are important in biology, being one of the main classes of lipids and comprising the bulk of animal fats and vegetable oils.Application of 169339-41-7 They perform as high-grade solvents for a broad array of plastics, plasticizers, resins, and lacquers, and are one of the largest classes of synthetic lubricants on the commercial market. Polyesters are important plastics, with monomers linked by ester moieties.

Application of 169339-41-7On October 6, 1995 ,《A Convergent Synthesis of 14-Membered F-O-G Ring Analogs of the Teicoplanin Binding Pocket via Intramolecular SNAr Reaction》 was published in Journal of Organic Chemistry. The article was written by Zhu, Jieping; Beugelmans, Rene; Bourdet, Sebastien; Chastanet, Jacqueline; Roussi, George. The article contains the following contents:

An intramol. SNAr reaction for efficient macrocyclization via biaryl ether formation was developed for syntheses of the 14-membered macrocycles I and II (R = NH2, NO2) related to F-O-G ring of teicoplanin. Chloride as well as fluoride could be used as the leaving group in this reaction. However, the latter was preferred since it required milder conditions. Both ortho and para nitro, fluoro disubstituted aromatic rings were suitable for the macrocyclization reaction with tethered aryl oxides. The nonproteinogenic α-amino acid III, required for the synthesis of II, was prepared via an asym. Strecker synthesis using (R)-phenylglycinol as a chiral auxiliary. The overall synthetic strategy was convergent, and the cyclization could be performed in the presence of the highly sensitive arylglycine unit without racemization.Methyl 2-(3-fluoro-4-nitrophenyl)acetate(cas: 169339-41-7Application of 169339-41-7) was used in this study.

Methyl 2-(3-fluoro-4-nitrophenyl)acetate(cas: 169339-41-7) belongs to esters. They are important in biology, being one of the main classes of lipids and comprising the bulk of animal fats and vegetable oils.Application of 169339-41-7 They perform as high-grade solvents for a broad array of plastics, plasticizers, resins, and lacquers, and are one of the largest classes of synthetic lubricants on the commercial market. Polyesters are important plastics, with monomers linked by ester moieties.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Chung, Jae-Uk’s team published research in Bioorganic & Medicinal Chemistry in 2007 | CAS: 169339-41-7

Methyl 2-(3-fluoro-4-nitrophenyl)acetate(cas: 169339-41-7) belongs to esters.Name: Methyl 2-(3-fluoro-4-nitrophenyl)acetate They are important in biology, being one of the main classes of lipids and comprising the bulk of animal fats and vegetable oils.Esters typically have a pleasant smell; those of low molecular weight are commonly used as fragrances and are found in essential oils and pheromones.

Name: Methyl 2-(3-fluoro-4-nitrophenyl)acetateOn September 15, 2007 ,《α-Substituted N-(4-tert-butylbenzyl)-N’-[4-(methylsulfonylamino)benzyl]thiourea analogues as potent and stereospecific TRPV1 antagonists》 was published in Bioorganic & Medicinal Chemistry. The article was written by Chung, Jae-Uk; Kim, Su Yeon; Lim, Ju-Ok; Choi, Hyun-Kyung; Kang, Sang-Uk; Yoon, Hae-Seok; Ryu, HyungChul; Kang, Dong Wook; Lee, Jeewoo; Kang, Bomi; Choi, Sun; Toth, Attila; Pearce, Larry V.; Pavlyukovets, Vladimir A.; Lundberg, Daniel J.; Blumberg, Peter M.. The article contains the following contents:

A series of α-substituted N-(4-tert-butylbenzyl)-N’-[4-(methylsulfonylamino)benzyl]thiourea analogs have been investigated as TRPV1 receptor antagonists. α-Me substituted analogs showed potent and stereospecific antagonism to the action of capsaicin on rat TRPV1 heterologously expressed in Chinese hamster ovary cells. In particular, compounds (I and II), which possess the R-configuration, exhibited excellent potencies (resp., Ki = 41 and 39.2 nM and Ki(ant) = 4.5 and 37 nM).Methyl 2-(3-fluoro-4-nitrophenyl)acetate(cas: 169339-41-7Name: Methyl 2-(3-fluoro-4-nitrophenyl)acetate) was used in this study.

Methyl 2-(3-fluoro-4-nitrophenyl)acetate(cas: 169339-41-7) belongs to esters.Name: Methyl 2-(3-fluoro-4-nitrophenyl)acetate They are important in biology, being one of the main classes of lipids and comprising the bulk of animal fats and vegetable oils.Esters typically have a pleasant smell; those of low molecular weight are commonly used as fragrances and are found in essential oils and pheromones.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics