Category: 15399-05-0

A new and facile method for the direct preparation of 浼?hydroxy carboxylic acid esters from 浼?灏?unsaturated carboxylic acid esters with molecular oxygen and phenylsilane catalyzed by bis(dipivaloylmethanato)manganese(II) complex was written by Inoki, Satoshi;Kato, Koji;Isayama, Shigeru;Mukaiyama, Teruaki. And the article was included in Chemistry Letters in 1990.HPLC of Formula: 15399-05-0 This article mentions the following:

The regioselective oxygenation of 浼?灏?unsaturated carboxylates was catalyzed by bis(pivaloylmethanato)manganese(II) in the presence of PhSiH₃. E.g., the oxygenation of (E)-MeCH:CHCO₂CH₂Ph gave 91% EtCH(OH)CO₂CH₂Ph. The oxygenation of di-Me fumarate and di-Me maleate gave di-Me malate. The reaction proceeds presumably via a radical process. In the experiment, the researchers used many compounds, for example, Ethyl 2-hydroxy-3-phenylpropanoate (cas: 15399-05-0HPLC of Formula: 15399-05-0).

Ethyl 2-hydroxy-3-phenylpropanoate (cas: 15399-05-0) belongs to esters. Esters are also usually derived from carboxylic acids. It may also be obtained by reaction of acid anhydride or acid halides with alcohols or by the reaction of salts of carboxylic acids with alkyl halides. Esterification is the general name for a chemical reaction in which two reactants (typically an alcohol and an acid) form an ester as the reaction product. Esters are common in organic chemistry and biological materials.HPLC of Formula: 15399-05-0

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Resolution of secondary alcohols via Carica papaya lipase-catalyzed enantioselective acylation was written by Miyazawa, Toshifumi;Houhashi, Mika;Inoue, Yusuke;Murashima, Takashi;Yamada, Takashi. And the article was included in Biotechnology Letters in 2008.Application of 15399-05-0 This article mentions the following:

The Carica papaya lipase-catalyzed acylation of benzylcarbinols with vinyl hexanoate proceeded smoothly and enantiospecifically (E > 200), affording the R-esters and leaving the S-alcs. intact. Thus, this plant lipase proved to be a promising biocatalyst for the resolution of alcs. as well as for that of carboxylic acids reported earlier. In the experiment, the researchers used many compounds, for example, Ethyl 2-hydroxy-3-phenylpropanoate (cas: 15399-05-0Application of 15399-05-0).

Ethyl 2-hydroxy-3-phenylpropanoate (cas: 15399-05-0) belongs to esters. Esters perform as high-grade solvents for a broad array of plastics, plasticizers, resins, and lacquers, and are one of the largest classes of synthetic lubricants on the commercial market. Esters are more polar than ethers but less polar than alcohols. They participate in hydrogen bonds as hydrogen-bond acceptors, but cannot act as hydrogen-bond donors, unlike their parent alcohols. This ability to participate in hydrogen bonding confers some water-solubility.Application of 15399-05-0

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Competing O-H insertion and 灏?elimination in rhodium carbenoid reactions; synthesis of 2-alkoxy-3-arylpropanoates was written by Cox, Geoffrey G.;Haigh, David;Hindley, Richard M.;Miller, David J.;Moody, Christopher J.. And the article was included in Tetrahedron Letters in 1994.Related Products of 15399-05-0 This article mentions the following:

Rhodium(II) carboxylate catalyzed decomposition of diazo esters 3 (shown as I) and PhCH₂C(CO₂Et)N₂鑱?strong>4 in the presence of alcs. or water results in formation of 2-alkoxy- or 2-hydroxy-3-arylpropanoates, resp., by O-H insertion in competition with cinnamates by elimination; the ratio of insertion to elimination is dramatically affected by the carboxylate ligand on rhodium. Use of methanol-d as the alc. confirms that the alkene does not arise by elimination from the initial alkoxyester product. In the experiment, the researchers used many compounds, for example, Ethyl 2-hydroxy-3-phenylpropanoate (cas: 15399-05-0Related Products of 15399-05-0).

Ethyl 2-hydroxy-3-phenylpropanoate (cas: 15399-05-0) belongs to esters. Esters typically have a pleasant smell; those of low molecular weight are commonly used as fragrances and are found in essential oils and pheromones. Esterification is the general name for a chemical reaction in which two reactants (typically an alcohol and an acid) form an ester as the reaction product. Esters are common in organic chemistry and biological materials.Related Products of 15399-05-0

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

An inquiry into the enzyme-catalyzed hydrolysis of leucine ethyl ester by chymotrypsin was written by Goldenberg, Harry;Goldenberg, Vivian;McLaren, A. D.. And the article was included in Biochimica et Biophysica Acta in 1951.Reference of 15399-05-0 This article mentions the following:

Ethyl esters of L-leucine and L-灏?phenyllactic acid and acetyl-DL-phenylalanine hydrazide were slowly hydrolyzed by chymotrypsin. Hydrolysis of ethyl esters of L-phenylalanine, L-tyrosine, acetyl-DL-phenylalanine, chloroacetyl-DL-phenylalanine, and of acetyl-DL-phenylalanine thioethyl ester was more rapid. In the experiment, the researchers used many compounds, for example, Ethyl 2-hydroxy-3-phenylpropanoate (cas: 15399-05-0Reference of 15399-05-0).

Ethyl 2-hydroxy-3-phenylpropanoate (cas: 15399-05-0) belongs to esters. Carboxylic acid esters of low molecular weight are colourless, volatile liquids with pleasant odours, slightly soluble in water. Esters contain a carbonyl center, which gives rise to 120鎺?C閳ユ弲閳ユ彊 and O閳ユ弲閳ユ彊 angles. Unlike amides, esters are structurally flexible functional groups because rotation about the C閳ユ彊閳ユ弲 bonds has a low barrier. Their flexibility and low polarity is manifested in their physical properties; they tend to be less rigid (lower melting point) and more volatile (lower boiling point) than the corresponding amides. Reference of 15399-05-0

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Influence of the dominance of must fermentation by Torulaspora delbrueckii on the malolactic fermentation and organoleptic quality of red table wine was written by Ramirez, Manuel;Velazquez, Rocio;Maqueda, Matilde;Zamora, Emiliano;Lopez-Pineiro, Antonio;Hernandez, Luis M.. And the article was included in International Journal of Food Microbiology in 2016.Name: Ethyl 2-hydroxy-3-phenylpropanoate This article mentions the following:

Torulaspora delbrueckii can improve wine aroma complexity, but its impact on wine quality is still far from being satisfactory at the winery level, mainly because it is easily replaced by S. cerevisiae yeasts during must fermentation New T. delbrueckii killer strains were selected to overcome this problem. These strains killed S. cerevisiae yeasts and dominated fermentation better than T. delbrueckii non-killer strains when they were single-inoculated into crushed red grape must. All the T. delbrueckii wines, but none of the S. cerevisiae wines, underwent malolactic fermentation Putative lactic acid bacteria were always found in the T. delbrueckii wines, but none or very few in the S. cerevisiae wines. Malic acid degradation was the greatest in the wines inoculated with the killer strains, and these strains reached the greatest dominance ratios and had the slowest fermentation kinetics. The T. delbrueckii wines had dried-fruit/pastry aromas, but low intensities of fresh-fruit aromas. The aroma differences between the T. delbrueckii and the S. cerevisiae wines can be explained by the differences that were found in the amounts of some fruity aroma compounds such as isoamyl acetate, Et hexanoate, Et octanoate, and some lactones. This T. delbrueckii effect significantly raised the organoleptic quality scores of full-bodied Cabernet-Sauvignon red wines inoculated with the killer strains. In particular, these wines were judged as having excellent aroma complexity, mouth-feel, and sweetness. In the experiment, the researchers used many compounds, for example, Ethyl 2-hydroxy-3-phenylpropanoate (cas: 15399-05-0Name: Ethyl 2-hydroxy-3-phenylpropanoate).

Ethyl 2-hydroxy-3-phenylpropanoate (cas: 15399-05-0) belongs to esters. Carboxylic acid esters of low molecular weight are colourless, volatile liquids with pleasant odours, slightly soluble in water. Many esters have the potential for conformational isomerism, but they tend to adopt an s-cis (or Z) conformation rather than the s-trans (or E) alternative, due to a combination of hyperconjugation and dipole minimization effects. The preference for the Z conformation is influenced by the nature of the substituents and solvent, if present. Lactones with small rings are restricted to the s-trans (i.e. E) conformation due to their cyclic structure.Name: Ethyl 2-hydroxy-3-phenylpropanoate

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Asymmetric reduction of 2-chloro-3-oxo-ester into enantiomerically high pure diltiazem precursor by a Candida ketoreductase was written by Chen, Cheng;Xuan, Yang;Chen, Qi;Ni, Guo-Wei;Pan, Jiang;Xu, Jian-He. And the article was included in Molecular Catalysis in 2021.Related Products of 15399-05-0 This article mentions the following:

Me (2R,3S)-3-(4-methoxyphenyl)glycidate [(2R,3S)-MPGM] is an advanced chiral synthon for the synthesis of the cardiovascular drug diltiazem. It can be easily accessed by cyclizing the reduction products of Me 2-chloro-3-(4-methoxyphenyl)-3-oxo-propanoate. Herein, we report an identified carbonyl reductase (CpKR) from Candida parapsilosis that displayed an excellent stereoselectivity toward the keto substituent at the C₃-position of the 2-chloro-3-oxo-ester. The engineered Escherichia coli cells harboring CpKR gene were directly applied for the asym. reduction of keto ester 1a with a space-time yield of 46 g L^-1 d^-1, which represents the highest productivity in bio-reduction reported so far. The isolated chiral alc. products were then applied to the chem. synthesis of (2R,3S)-MPGM in 99% ee and a total yield of 76% in the two-step chemo-enzymic reactions, which far exceeded the maximum theor. yield (50%) of the existing industrial process based on a lipase-catalyzed resolution of racemic MPGM. This work provides a promising eco-friendly and cost-effective route toward industrial synthesis of pharmaceutically relevant diltiazem. In the experiment, the researchers used many compounds, for example, Ethyl 2-hydroxy-3-phenylpropanoate (cas: 15399-05-0Related Products of 15399-05-0).

Ethyl 2-hydroxy-3-phenylpropanoate (cas: 15399-05-0) belongs to esters. Esters perform as high-grade solvents for a broad array of plastics, plasticizers, resins, and lacquers, and are one of the largest classes of synthetic lubricants on the commercial market. Polyesters are important plastics, with monomers linked by ester moieties. Esters are more polar than ethers but less polar than alcohols. They participate in hydrogen bonds as hydrogen-bond acceptors, but cannot act as hydrogen-bond donors, unlike their parent alcohols. This ability to participate in hydrogen bonding confers some water-solubility.Related Products of 15399-05-0

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

The preparation and properties of a platinized charcoal catalyst with some observations on the behavior of inhibitors was written by Baltzly, Richard. And the article was included in Journal of the American Chemical Society in 1952.Computed Properties of C11H14O3 This article mentions the following:

A Pt-C catalyst (I) notable for its inactivity in debenzylation and in dehalogenations has been developed and tested on a variety of reducible compounds It appears to reduce aliphatic CO compounds less readily than aromatic. Both I and Pd-C are inhibited toward the reduction of control substrates by bases and nucleophilic ions. To 1 g. C (Darco G-60) in the reducing bottle of a Burgess-Parr hydrogenator was added 30-50 cc. H₂O and solutions of H₂PtCl₆ and PdCl₂ containing 100 mg. Pt and 0.2 mg. Pd, resp., the bottle evacuated, filled with H, shaken 15-20 min., and the H₂O finally replaced by MeOH; when not in use, the I was stored under MeOH in a reducing bottle. The hydrogenations with I were performed in MeOH at room temperature, in general with 50 millimoles substrate in 50 cc. MeOH. A series of hydrogenations was carried out in this manner; the substrate, the hydrogenation absorption, and, where determined, the hydrogenation products, of these runs are listed in the following (H absorption rates of 5-10 millimoles/min. are marked fast, 1-5 millimoles/min. moderate, < 1 millimole/min. slow; products in parentheses were not specifically isolated but were present with reasonable certainty): cyclohexene, 1 mole very fast (cyclohexane); CH₂:CHCH₂-Cl, 1 mole moderate (C₃H₈, PrCl, HCl); PhCH₂Cl, 1 mole slow (PhMe); PhCH₂OH, about 0.2 mole very slow (Ph-Me ?, substrate possibly contaminated with PhCH₂Cl); (PhCH₂)₂O, none; PhCH₂OCONHCH₂CO₂H, none; PhNMeCH₂Ph.HCl, none; p-ClC₆H₄NH₂, none; o-ClC₆H₄NH₂, none; m-BrC₆H₄Me, none; o-BrC₆H₄OMe, very slow, -; o-BrC₆H₄CO₂Et, none; p-ClC₆H₄OC₆H₄NO₂-p, 3 moles, very fast, p-ClC₆H₄OC₆H₄NH₂-p; (PhN:)₂ + 2 moles AcOH, 1 mole very fast, 1 mole moderate (PhNH₂); (PhN:)₂, 1 mole very fast, 1 mole slow [PhNH₂, (PhNH)₂]; (PhN:)₂ in 0.019N NaOH, 1 mole very fast, (PhNH)₂; 2, 6-dimethyl-4-hydroxy-5-phenylazo-4-pyrimidinol-HCl, 2 moles fast, 5-amino-2,6-dimethyl-4-pyrimidinol (+ Ph-NH₂); PhCH:NMe, fast, PhCH₂NHMe; p-MeOC₆H₄-CH:NCHPhMe + 1.5 moles AcOH, fast, p-MeOC₆H₄CH₂-NHCHPhMe; 2, 5-(MeO)₂C₆H₃COC(:NOH)Me + 3 moles HCl, 2 moles moderate, 2, 5-(MeO)₂C₆H₃COCH(NH₂)Me.-HCl; PhCN + HCl, none; PhCH₂CN + HCl, none; PhCH₂C(:NOH)Ph, none; AcH, very slow (EtOH) AcH + morpholine, 1 mole moderate (ethylmorpholine); cyclohexanone, none; Me₂CO, none; Me₂CO + cyclohexylamine, very slow, -; p-MeOC₆H₄CHO, 1 mole moderate (anisyl alc.); p-MeOC₆H₄CHO + BuNH₂, 1 mole slow, p-MeOC₆H₄CH₂NHBu; p-HOC₆H₄Ac, 1 mole slow, polymerized product; PhCH:CHCHO, 2 moles moderate (Ph(CH₂)₃OH); AcCH₂CO₂Et, none; BzCH₂CO₂-Et, 1 mole slow, PhCH(OH)CH₂CO₂Et; 3, 4-MeO(HO)-C₆H₃CH:CAcCO₂Et, 1 mole moderate, 3, 4-MeO(HO)-C₆H₃CH₂CHAcCO₂Et; 3,4-(MeO)₂C₆H₃CH: CAcCO₂Et, 1 mole moderate, 3, 4-(MeO)₂C₆H₃CH₂CHAcCO₂Et; Ph₂CO, none; PhCH₂Bz, none; benzanisoine, none; C₆H₆ in glacial AcOH, slow not carried to completion (cyclohexane ?); C₁₀H₈ in glacial AcOH, none at 25°. Both I and Pd-C were tested with control substrates in the presence of various concentrations of inhibitors and the half-inhibitory M concentrations (given for I and Pd-C) determined for: MeO^– 0.001, 0.001; PhO^– 0.006, 0.006; I^– 0.0004, 0.0004; CN^– < 0.001, -; NH₃ 0.002, 0.002; PhCH₂NMe₂ 0.001, 0.001; and p-MeC₆H₄NH₂ 0.007, 0.005-0.006. In the experiment, the researchers used many compounds, for example, Ethyl 2-hydroxy-3-phenylpropanoate (cas: 15399-05-0Computed Properties of C11H14O3).

Ethyl 2-hydroxy-3-phenylpropanoate (cas: 15399-05-0) belongs to esters. Esters typically have a pleasant smell; those of low molecular weight are commonly used as fragrances and are found in essential oils and pheromones. Esters are more polar than ethers but less polar than alcohols. They participate in hydrogen bonds as hydrogen-bond acceptors, but cannot act as hydrogen-bond donors, unlike their parent alcohols. This ability to participate in hydrogen bonding confers some water-solubility.Computed Properties of C11H14O3

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Synthesis and antiinflammatory activity of cis- and trans-6,6a,7,8,9,10,10a,11-octahydro-11-oxodibenzo[b,e]thiepinacetic and -oxepinacetic acids was written by Kurokawa, Mikio;Uno, Hitoshi;Nakamura, Hideo;Sato, Fuminori;Naruto, Shunsuke. And the article was included in Journal of Medicinal Chemistry in 1990.Synthetic Route of C11H14O3 This article mentions the following:

Eight cis– and trans-6,6a,7,8,9,10,10a,11-octahydro-11-oxodibenzo[b,e]thiepin- and -oxepinacetic acids I (X = S, O; R = 2- and 3-CH₂CO₂H and -CHMeCO₂H) were prepared, and their antiinflammatory activities were examined in the rat carrageenan hind-paw edema test. The antiinflammatory activity depended on the configurations at C-6a, C-10a, and C-2 of the acetic moiety. The 6a,10a-trans compounds exhibited considerable antiinflammatory activity, while the 6a,10a-cis compounds were inactive. Among the trans compounds, I (X = S, O; R = 3-CHMeCO₂H) showed antiinflammatory activity superior to that of indomethacin. Trans phenethyl ester I (X = S; R = 3-CHMeCO₂CH₂CH₂Ph) (II) showed potent antiinflammatory activity, and its safety index was >14 times as high as that of indomethacin. II is the most favorable compound with high antiinflammatory activity and little ulcerogenicity. In the experiment, the researchers used many compounds, for example, Ethyl 2-hydroxy-3-phenylpropanoate (cas: 15399-05-0Synthetic Route of C11H14O3).

Ethyl 2-hydroxy-3-phenylpropanoate (cas: 15399-05-0) belongs to esters. Esters are also usually derived from carboxylic acids. It may also be obtained by reaction of acid anhydride or acid halides with alcohols or by the reaction of salts of carboxylic acids with alkyl halides. Cyclic esters are called lactones, regardless of whether they are derived from an organic or inorganic acid. One example of an organic lactone is γ-valerolactone.Synthetic Route of C11H14O3

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Gas chromatographic enantiomer separation of mandelates and its analogs on permethylated cyclodextrin chiral stationary phases was written by Nie, Mengyan;Zhou, Liangmo;Wang, Qinghai;Zhu, Taoqian. And the article was included in Fenxi Huaxue in 2000.Name: Ethyl 2-hydroxy-3-phenylpropanoate This article mentions the following:

Gas chromatog. enantiomer separation of mandelates and its analogs was studied on permethylated β-cyclodextrin (PMBCD) and permethylated γ-cyclodextrin (PMGCD) chiral stationary phases (CSPs). The compounds studied included Me and Et mandelates, Me and Et α-methoxymandelates, Me and Et 3-phenylacetates, Et 2-hydroxy-4-Ph butyrate. All the compounds studied can be chirally separated to baseline on PMBCD CSPs, but no enantiomer separation was observed on PMGCD CSPs for all the tested compounds Some thermodn. data were evaluated for the mechanism of chiral recognition between permethylated cyclodextrins and mandelates and their analogs. In the experiment, the researchers used many compounds, for example, Ethyl 2-hydroxy-3-phenylpropanoate (cas: 15399-05-0Name: Ethyl 2-hydroxy-3-phenylpropanoate).

Ethyl 2-hydroxy-3-phenylpropanoate (cas: 15399-05-0) belongs to esters. Esters are widespread in nature and are widely used in industry. In nature, fats are in general triesters derived from glycerol and fatty acids. Esters are responsible for the aroma of many fruits. Cyclic esters are called lactones, regardless of whether they are derived from an organic or inorganic acid. One example of an organic lactone is γ-valerolactone.Name: Ethyl 2-hydroxy-3-phenylpropanoate

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

The flavor of sparkling wine was written by Takahagi, Naoto. And the article was included in Koryo in 2020.Category: esters-buliding-blocks This article mentions the following:

A sparkling wine is a wine made fizzy by carbon dioxide bubbles. There are two main methods to brew a sparkling wine. The first is to add sugar and yeast to the wine for secondary fermentation, and then to trap the carbon dioxide gas generated in a bottle. The second method is to blow carbon dioxide gas directly into the wine. Champagne is a typical sparkling wine. Canned sparkling wines have helped to vitalize the wine market in Japan in recent years. Our group analyzed the volatile components of champagne and canned sparkling wine using GC and GC-MS. In this paper, the author report the differences in the volatile components detected in the two beverages. In the experiment, the researchers used many compounds, for example, Ethyl 2-hydroxy-3-phenylpropanoate (cas: 15399-05-0Category: esters-buliding-blocks).

Ethyl 2-hydroxy-3-phenylpropanoate (cas: 15399-05-0) belongs to esters. Volatile esters with characteristic odours are used in synthetic flavours, perfumes, and cosmetics. Certain volatile esters are used as solvents for lacquers, paints, and varnishes. Esters contain a carbonyl center, which gives rise to 120° C–C–O and O–C–O angles. Unlike amides, esters are structurally flexible functional groups because rotation about the C–O–C bonds has a low barrier. Their flexibility and low polarity is manifested in their physical properties; they tend to be less rigid (lower melting point) and more volatile (lower boiling point) than the corresponding amides. Category: esters-buliding-blocks

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics