Category: 149437-67-2

Reductive aminations of carbonyl compounds with borohydride and borane reducing agents was written by Baxter, Ellen W.;Reitz, Allen B.. And the article was included in Organic Reactions (Hoboken, NJ, United States) in 2002.Product Details of 149437-67-2 The following contents are mentioned in the article:

A review of the article Reductive aminations of carbonyl compounds with borohydride and borane reducing agents. This study involved multiple reactions and reactants, such as Methyl 5-(4-fluorophenyl)-5-oxopentanoate (cas: 149437-67-2Product Details of 149437-67-2).

Methyl 5-(4-fluorophenyl)-5-oxopentanoate (cas: 149437-67-2) belongs to esters. Volatile esters with characteristic odours are used in synthetic flavours, perfumes, and cosmetics. Certain volatile esters are used as solvents for lacquers, paints, and varnishes. Because of their lack of hydrogen-bond-donating ability, esters do not self-associate. Consequently, esters are more volatile than carboxylic acids of similar molecular weight.Product Details of 149437-67-2

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Asymmetric Iodolactonization Utilizing Chiral Squaramides was written by Tungen, Joern E.;Nolsoee, Jens M. J.;Hansen, Trond V.. And the article was included in Organic Letters in 2012.Synthetic Route of C12H13FO3 The following contents are mentioned in the article:

Asym. iodolactonization of γ- and δ-unsaturated carboxylic acids has been explored in the presence of six different chiral organocatalysts 5-8. The catalyst I was found to facilitate the cyclization of 5-arylhex-5-enoic acids to the corresponding iodolactones with up to 96% ee. By this protocol, unsaturated carboxylic acids are converted enantioselectively to synthetically useful δ-lactones in high yields using com. available NIS. Apparently, both hydrogen bonding and aryl/aryl interactions are important for efficient stereodifferentiation. This study involved multiple reactions and reactants, such as Methyl 5-(4-fluorophenyl)-5-oxopentanoate (cas: 149437-67-2Synthetic Route of C12H13FO3).

Methyl 5-(4-fluorophenyl)-5-oxopentanoate (cas: 149437-67-2) belongs to esters. Esters are widespread in nature and are widely used in industry. In nature, fats are in general triesters derived from glycerol and fatty acids. Esters are responsible for the aroma of many fruits. Many esters have the potential for conformational isomerism, but they tend to adopt an s-cis (or Z) conformation rather than the s-trans (or E) alternative, due to a combination of hyperconjugation and dipole minimization effects. The preference for the Z conformation is influenced by the nature of the substituents and solvent, if present. Lactones with small rings are restricted to the s-trans (i.e. E) conformation due to their cyclic structure.Synthetic Route of C12H13FO3

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Asymmetric bromolactonization catalyzed by a C₃-symmetric chiral trisimidazoline was written by Murai, Kenichi;Matsushita, Tomoyo;Nakamura, Akira;Fukushima, Shunsuke;Shimura, Masato;Fujioka, Hiromichi. And the article was included in Angewandte Chemie, International Edition in 2010.Product Details of 149437-67-2 The following contents are mentioned in the article:

Enantioselective bromolactonization of 5-substituted 5-hexenoic acids catalyzed by the trisimidazoline have generated 6-(Bromomethyl)-6-aryltetrahydro-2H-pyran-2-ones e. g., I (R = Ph, 4-Cl-C₆H₄, 4-Br-C₆H₄, 4-F-C₆H₄, 4-Me-C₆H₄, 4-MeO-C₆H₄, 2,4-Me₂C₆H₃, 2-naphthyl, cyclohexyl). Debromination of 6-(bromomethyl)-6-(4-chlorophenyl)tetrahydro-2H-pyran-2-one leads to enantioselective derivatives II (R = H, SAc, N₃) and III. This study involved multiple reactions and reactants, such as Methyl 5-(4-fluorophenyl)-5-oxopentanoate (cas: 149437-67-2Product Details of 149437-67-2).

Methyl 5-(4-fluorophenyl)-5-oxopentanoate (cas: 149437-67-2) belongs to esters. Esters perform as high-grade solvents for a broad array of plastics, plasticizers, resins, and lacquers, and are one of the largest classes of synthetic lubricants on the commercial market. Polyesters are important plastics, with monomers linked by ester moieties. Esters contain a carbonyl center, which gives rise to 120° C–C–O and O–C–O angles. Unlike amides, esters are structurally flexible functional groups because rotation about the C–O–C bonds has a low barrier. Their flexibility and low polarity is manifested in their physical properties; they tend to be less rigid (lower melting point) and more volatile (lower boiling point) than the corresponding amides. Product Details of 149437-67-2

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Cobalt-Catalyzed Asymmetric Hydrogenation of 1,1-Diarylethenes was written by Chen, Jianhui;Chen, Chenhui;Ji, Chonglei;Lu, Zhan. And the article was included in Organic Letters in 2016.Computed Properties of C12H13FO3 The following contents are mentioned in the article:

Highly enantioselective cobalt-catalyzed hydrogenation of 1,1-diarylethenes was developed by using bench-stable chiral oxazoline iminopyridine-cobalt complexes as precatalysts. Thus, (vinylphenyl)pyrrole I gave (phenylethyl)pyrrole II in 97% yield and 92% ee. A unique o-chloride effect was observed to achieve high enantioselectivity. Easy removal as well as further transformations of the chloro group make this protocol a potentially useful alternative to synthesize various chiral 1,1-diarylethanes. This process can be successfully performed under 1 atm of hydrogen at room temperature on gram scale. This study involved multiple reactions and reactants, such as Methyl 5-(4-fluorophenyl)-5-oxopentanoate (cas: 149437-67-2Computed Properties of C12H13FO3).

Methyl 5-(4-fluorophenyl)-5-oxopentanoate (cas: 149437-67-2) belongs to esters. Esters are also usually derived from carboxylic acids. It may also be obtained by reaction of acid anhydride or acid halides with alcohols or by the reaction of salts of carboxylic acids with alkyl halides. Esterification is the general name for a chemical reaction in which two reactants (typically an alcohol and an acid) form an ester as the reaction product. Esters are common in organic chemistry and biological materials.Computed Properties of C12H13FO3

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Synthesis of 2,5-substituted piperidines: transposition of 1,4-substitution pattern for the analgesic drug R6582 was written by Baens, Nicole P.;Compernolle, Frans;Toppet, Suzanne M.;Hoornaert, Georges J.. And the article was included in Tetrahedron in 1993.HPLC of Formula: 149437-67-2 The following contents are mentioned in the article:

Cis-5-(1,3-dihydro-2-oxo-2H-benzimidazol-1-yl)-2-p-fluorophenyl-1-methylpiperidine I R = H) and the analogous cis- and trans-1-benzylpiperidines II (R = Ph) were prepared Key steps in the synthesis were the α-chlorination of 1-methyl- and 1-benzyl-6-p-fluorophenyl-2-piperidinone, and nucleophilic substitution of the resulting cis and trans 3-chloro lactams. ¹H NMR anal. for the epimeric 3,6-substituted lactam compounds revealed a preferred axial orientations for the 3-chloro substituent and an equatorial orientation for the 3-(oxobenzimidazolyl) group. For I, a conformational equilibrium was observed This was shifted to the [2ax,5eq] form for II (R = H). This study involved multiple reactions and reactants, such as Methyl 5-(4-fluorophenyl)-5-oxopentanoate (cas: 149437-67-2HPLC of Formula: 149437-67-2).

Methyl 5-(4-fluorophenyl)-5-oxopentanoate (cas: 149437-67-2) belongs to esters. Esters perform as high-grade solvents for a broad array of plastics, plasticizers, resins, and lacquers, and are one of the largest classes of synthetic lubricants on the commercial market. Esterification is the general name for a chemical reaction in which two reactants (typically an alcohol and an acid) form an ester as the reaction product. Esters are common in organic chemistry and biological materials.HPLC of Formula: 149437-67-2

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Crystallographic Understanding of Photoelectric Properties for C₆₀ Derivatives Applicable as Electron Transporting Materials in Perovskite Solar Cells was written by Xing, Zhou;Li, Shu-Hui;Xu, Piao-Yang;Tian, Han-Rui;Deng, Lin-Long;Yao, Yang-Rong;Chen, Bin-Wen;Xie, Fang-Fang;An, Ming-Wei;Yun, Da-Qin;Xie, Su-Yuan;Zheng, Lan-Sun. And the article was included in Chemical Research in Chinese Universities in 2022.Category: esters-buliding-blocks The following contents are mentioned in the article:

Hundreds of C₆₀ derivatives stand out as electrontransporting materials(ETMs), for example, in perovskite solar cells(PSCs), due to their properties on electron extraction or defect passivation. However, it still lacks of guidelines to update C60-based ETMs with excellent photoelec. properties. In this work, crystallog. data of eight C₆₀-based ETMs, including pristine C₆₀ and the well-known PCBM as well as six newly synthesized fullerenes, are analyzed to establish the connections between derivatized structures and photoelec. properties for the typical carbon cluster of C₆₀. In terms of packing centroid-centroid distance between neighboring carbon cages, the crystallog. data are useful for probing photoelec. properties, such as electrochem. properties, electron mobility and photovoltaic performances, and therefore facilitate to design novel C₆₀-based ETMs for PSCs with high performances. This study involved multiple reactions and reactants, such as Methyl 5-(4-fluorophenyl)-5-oxopentanoate (cas: 149437-67-2Category: esters-buliding-blocks).

Methyl 5-(4-fluorophenyl)-5-oxopentanoate (cas: 149437-67-2) belongs to esters. Esters are widespread in nature and are widely used in industry. In nature, fats are in general triesters derived from glycerol and fatty acids. Esters are responsible for the aroma of many fruits, including apples, durians, pears, bananas, pineapples, and strawberries. Liquid esters of low volatility serve as softening agents for resins and plastics. Esters also include many industrially important polymers. Polymethyl methacrylate is a glass substitute sold under the names Lucite and Plexiglas; polyethylene terephthalate is used as a film (Mylar) and as textile fibres sold as Terylene, Fortrel, and Dacron.Category: esters-buliding-blocks

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Conversion of γ- and δ-Keto Esters into Optically Active Lactams. Transaminases in Cascade Processes was written by Mourelle-Insua, Angela;Zampieri, Luiz Arthur;Lavandera, Ivan;Gotor-Fernandez, Vicente. And the article was included in Advanced Synthesis & Catalysis in 2018.Formula: C12H13FO3 The following contents are mentioned in the article:

A one-pot two-step enzymic strategy has been designed for the production of optically active γ- and δ-lactams in aqueous medium under mild conditions. The approach is based on the biotransamination of Et or Me keto esters bearing different alkyl or aryl substitution patterns at α-position to the ketone functionality. In this manner, the keto esters were transformed into the corresponding amino esters with excellent conversions, which underwent spontaneous cyclisation in the reaction medium without addition of external reagents. Depending on the transaminase selectivity, both lactam enantiomers can be obtained, so initial enzyme screenings were performed using com. available and made in house enzymes. Reaction conditions were optimized focusing on the substrate concentration, temperature and ratio of amine donor vs acceptor. Thus, ten γ- and δ-lactams were obtained in good to high isolated yields (70-90%) and excellent selectivities (94-99%) after one or two days at 30 or 45 °C. This study involved multiple reactions and reactants, such as Methyl 5-(4-fluorophenyl)-5-oxopentanoate (cas: 149437-67-2Formula: C12H13FO3).

Methyl 5-(4-fluorophenyl)-5-oxopentanoate (cas: 149437-67-2) belongs to esters. Esters are also usually derived from carboxylic acids. It may also be obtained by reaction of acid anhydride or acid halides with alcohols or by the reaction of salts of carboxylic acids with alkyl halides. Esters contain a carbonyl center, which gives rise to 120° C–C–O and O–C–O angles. Unlike amides, esters are structurally flexible functional groups because rotation about the C–O–C bonds has a low barrier. Their flexibility and low polarity is manifested in their physical properties; they tend to be less rigid (lower melting point) and more volatile (lower boiling point) than the corresponding amides. Formula: C12H13FO3

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics