Related Products of 14630-09-2, In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 14630-09-2, name is Methyl thieno[3,4-b]thiophene-2-carboxylate belongs to esters-buliding-blocks compound, it is a common compound, a new synthetic route is introduced below.
4,6-Dibromo 2-perflurohexyl-thieno[3,4-b]thiophene (14): To a solution of 2.75 g (6.0 mmol) (5) in 15 mL DMF was added dropwise a solution of NBS (2.70 g, 15.0 mmol) in 15 mL DMF under nitrogen protection at dark. The reaction mixture was heated up to 40 C. and kept stirring for 24 h. Then it was cooled down, poured to saturated sodium sulfite solution at ice-water bath, and extracted with dichloromethane. The organic phase was collected and dried by sodium sulfate. Removal of the solvent, and column purification on silica gel using hexane as fluent yielded the target product (14) 3.32 g (90%). 1HNMR (CDCl3): delta 7.20 (1H, s) MS (EI): Calcd, 616.1. found (M+1)+, 616.7.
In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles, Methyl thieno[3,4-b]thiophene-2-carboxylate, other downstream synthetic routes, hurry up and to see.
Reference:
Patent; University of Chicago; Yu, Luping; Liang, Yongye; US9029499; (2015); B2;,
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