Electric Literature of 142-91-6, In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 142-91-6, name is Isopropyl palmitate belongs to esters-buliding-blocks compound, it is a common compound, a new synthetic route is introduced below.
1.41 g of isopropyl palmitate (manufactured by Wako Pure Chemical Industries Ltd.), 1.00 g of phytosphingosine,and 14 mL of ethanol were added in a 30-mL eggplant flask and the mixture was stirred in a 55C hot water bath for 15min. After it was confirmed that the reaction system was homogeneous, 17.7 mg of potassium hydroxide (manufacturedby Kanto Chemical Co. , Inc.) was added. After 2 hours, a precipitate was confirmed and the mixture was continuouslystirred during a whole day and night. After the resulting reaction mixture was cooled to 30C, the precipitate was filteredand washed to obtain 1.45 g of N-hexadecanoyl-phytosphingosine in the form of a white solid in a yield of 82.9% (purity:95%).Melting point 114-117CIR (ATR, cm-1) 3336, 2917, 2849, 1611, 1542, 1468, 1076, 717MS (positive): [M + H]+ = 556.7, [M + Na]+ = 584.71H-NMR (deuterated pyridine, 500MHz, delta) 0.85 (3H, t, J = 7.0Hz), 0.85 (3H, t, J = 7.0Hz), 1.16-1.49 (46H, br), 1.69 (1H,m), 1.82 (2H, m), 1.94(2H, m), 2.24 (1H, m), 2.45 (2H, t, J = 7.6Hz), 4.29 (1H, m), 4.40 (1H, ddd, J = 5.9, 5.9, 5.5Hz),4.49 (2H, m), 5.10 (1H, m), 6.19 (1H, d, J = 6.7Hz), 6.53 (1H, d, J=6.2Hz), 6.62 (1H, t, J=5.4Hz), 8.52 (1H, d, J=8.5Hz)
In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles, Isopropyl palmitate, other downstream synthetic routes, hurry up and to see.
Reference:
Patent; Kao Corporation; HASHIMOTO, Hiroshi; SUGAI, Yoshiya; EP2757090; (2014); A1;,
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics