Category: 1414887-27-6

Zhong, Sabilla; Hafner, Andreas; Hussal, Christoph; Nieger, Martin; Braese, Stefan published an article in 2015, the title of the article was Metal-free radical perfluoroalkylation of (hetero)arenes.Category: esters-buliding-blocks And the article contains the following content:

A metal-free radical perfluoroalkylation method which used inexpensive and com. available perfluorocarboxylic anhydrides as an easy to use source of perfluoroalkyl radicals was reported. This approach allowed the perfluoroalkylation of different arenes, such as benzene derivatives, furans, thiophenes, and pyrroles, including highly functionalized compounds The experimental process involved the reaction of Ethyl 5-(trifluoromethyl)-1H-pyrrole-2-carboxylate(cas: 1414887-27-6).Category: esters-buliding-blocks

The Article related to perfluoroalkylated arene preparation, arene perfluorocarboxylic anhydride perfluoroalkylation, Aliphatic Compounds: Halides and Halonium Compounds and other aspects.Category: esters-buliding-blocks

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

On July 8, 2021, Luo, Long; Nguyen, Hien M. published a patent.Application In Synthesis of Ethyl 5-(trifluoromethyl)-1H-pyrrole-2-carboxylate The title of the patent was Alternating current electrolysis for use in organic synthesis. And the patent contained the following:

The current disclosure provides a.c. based systems and methods to develop chem. compounds, such as drug mols. using electrochem. in organic synthesis. The experimental process involved the reaction of Ethyl 5-(trifluoromethyl)-1H-pyrrole-2-carboxylate(cas: 1414887-27-6).Application In Synthesis of Ethyl 5-(trifluoromethyl)-1H-pyrrole-2-carboxylate

The Article related to alternating current electrolysis organic synthesis, Electrochemistry: Nonindustrial Electrochemical Syntheses and Preparations and other aspects.Application In Synthesis of Ethyl 5-(trifluoromethyl)-1H-pyrrole-2-carboxylate

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Kondratov, Ivan S.; Dolovanyuk, Violetta G.; Tolmachova, Nataliya A.; Gerus, Igor I.; Bergander, Klaus; Froehlich, Roland; Haufe, Guenter published an article in 2012, the title of the article was Reactions of β-alkoxyvinyl polyfluoroalkyl ketones with ethyl isocyanoacetate and its use for the synthesis of new polyfluoroalkyl pyrroles and pyrrolidines.COA of Formula: C8H8F3NO2 And the article contains the following content:

The hitherto unreported reactions of β-alkoxyvinyl polyfluoroalkyl ketones with Et isocyanoacetate and equimolar amounts of potassium-tert-butoxide proceeded mainly in the β-position of the α,β-unsaturated ketones in cases of α-nonsubstituted I (R1 = CF3, CHF2, CF2Cl, C2F5, C3F7; R2 = H) and α-Me substituted ketones I (R1 = CHF2, CF2Cl, C2F5, C3F7; R2 = Me). Other α- or β-substituted ketones gave mainly products of initial attack at the carbonyl carbon. Depending on the solvent, the major products of β-attack do exist in different tautomeric forms. Generally the open-chain enol tautomers II (R2 = H only) predominate in the polar DMSO-d6, while the cyclic γ-hemiaminals III are the major tautomers in the less polar CDCl3. Acid treatment of the latter compounds III led to the hitherto unknown Et 5-polyfluoroalkyl-pyrrole-2-carboxylates by elimination of formic acid. Catalytic hydrogenation was used for the synthesis of earlier unknown 5-trifluoromethyl proline. The experimental process involved the reaction of Ethyl 5-(trifluoromethyl)-1H-pyrrole-2-carboxylate(cas: 1414887-27-6).COA of Formula: C8H8F3NO2

The Article related to alkoxyvinyl polyfluoroalkyl ketone ethyl isocyanoacetate regioselective substitution, open chain enol cyclic hemiaminal tautomer preparation elimination, pyrrole pyrrolidine polyfluoroalkyl preparation and other aspects.COA of Formula: C8H8F3NO2

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics