Category: 140-11-4

Gonzalez, Alexandre published the artcileExtraction and Identification of Volatile Organic Compounds in Scentless Flowers of 14 Tillandsia Species Using HS-SPME/GC-MS, Computed Properties of 140-11-4, the main research area is Tillandsia volatile organic compound flower mass spectrometry; PCA analysis; Tillandsia; faint-scented flowers; gas chromatography-mass spectrometry (GC-MS); headspace solid phase microextraction (HS-SPME); heatmap; scentless flowers; volatile organic compounds (VOCs).

VOCs emitted by flowers play an important role in plant ecol. In the past few years, the Tillandsia genus has been scarcely studied according to the VOCs emitted by flowers. Hence, we decided to enlarge the VOCs composition study already undergone in our laboratory on fragrant 3 Tillandsia species to 12 unscented and 2 faint-scented Tillandsia species and hybrids. The headspace solid phase microextraction (HS-SPME) coupled with gas chromatog. combined with the mass spectrometry (GC-MS) method was used to explore the chem. diversity of the VOCs. This study allowed the identification of 65 VOCs among the 14 species and between 6 to 25 compounds were identified in each of the species. The aromatic profile of 10 of the species and hybrids are similar to each other′s and show 8 predominant compounds: benzaldehyde, benzacetaldehyde, hexanol, hexanal, heptanal, octanal, nonanal, and furan-2-pentyl. Some specific compounds are present only in some unique species such as trans-calamenene, α-muurolene, and α-guaiene trans-β-bergamotene. The two faint-scented species studied present an original aromatic profile with a high number of monoterpenes or phenylpropanoids/benzenoids. Our studies allow a better understanding of the ecol. role and function of these VOCs in the interactions between these plants with their environment.

Metabolites published new progress about Aliphatic aldehydes Role: ANT (Analyte), BSU (Biological Study, Unclassified), PAC (Pharmacological Activity), THU (Therapeutic Use), ANST (Analytical Study), BIOL (Biological Study), USES (Uses). 140-11-4 belongs to class esters-buliding-blocks, name is Benzyl acetate, and the molecular formula is C9H10O2, Computed Properties of 140-11-4.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

These common heterocyclic compound, 140-11-4, name is Benzyl acetate, its traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc, below Introduce a new synthetic route. Application In Synthesis of Benzyl acetate

General procedure: Bioreactor cultures and biotransformations using E. coli JM109(pDTG601). Growth and biotransformation in the bioreactor usingE.coli JM109 (pDTG601) were carried out using a modification ofour previously published procedure.3b Thus, 5 mL of LB mediumsupplemented with ampicillin sodium salt (0.1 g/L) and glucose(5 g/L) were inoculated with a single colony of E. coli JM109(pDTG601), and grown overnight at 37 C and 150 rpm. Two500 mL shake-flasks containing 150 mL of MSB medium wereinoculated with 1 mL of the grown culture. These precultureflasks were placed in an orbital shaker at 37 C and 150 rpm, for12 hrs. Both entire cultures were used to inoculate the bioreactor(Sartorius Biostat A plus), charged with an initial volume of 2.5 L,and set to 500 rpm, 30 C, and air flow rate of 4L/min. The pHvalue was controlled automatically to 6.8 by addition of conc.ammonium hydroxide during the whole process. A pulse ofantifoam agents (Aldrich?s Antifoam Y: Silicone dispersion inwater 1:1) was added at the beginning of the run. At 6 h afterinoculation the dissolved oxygen value sharply increased(indicating carbon deprivation), whereupon a glucose fed-batchwas started by adding glucose (0.7 g/mL solution) from an initialrate of 0.08 mL/min to 0.54 mL/min in a 20 h period. When thebiomass concentration reached 15 g/L cdw, IPTG was added toinduce toluene dioxygenase expression (IPTG final concentrationin bioreactor of 10 mg/L), and the stirrer speed was set to900 rpm. After the culture reached the stationary phase (c.a.26 h, 50 g/L cdw aprox), glucose feeding was decreased to0.25 mL/min and substrate addition was started. A solution of thecorresponding substrate in liquid paraffin (0.5 M) was added at aflow rate of 20 mL/min using a peristaltic pump. After thebiotransformation was completed, the pH of the medium in thebioreactor was adjusted to 7.5. The culture broth was centrifugedat 7000 rpm and 4 C for 30 min, the supernatant was collectedand the cell pellet properly disposed. Centrifugation led to theseparation of the liquid paraffin (which contains no detectableamounts products) from the aqueous phase. The latter wasproperly lyophilized overnight to obtain a dry powder, whichwas extracted several times with ethyl acetate until no morediols were detected by TLC. The solvent was evaporated to affordthe corresponding diol, which was washed several times withhexanes to remove the liquid paraffin traces.

The synthetic route of Benzyl acetate has been constantly updated, and we look forward to future research findings.

Reference:
Article; Pazos, Mariana; Martinez, Sebastian; Vila, Maria Agustina; Rodriguez, Paola; Veiga, Nicolas; Seoane, Gustavo; Carrera, Ignacio; Tetrahedron Asymmetry; vol. 26; 24; (2015); p. 1436 – 1447;,
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Application of 140-11-4, These common heterocyclic compound, 140-11-4, name is Benzyl acetate, its traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc, below Introduce a new synthetic route.

In a 5 ml glass bottle into which the magnet was placed,Then add NaOEt (17 mg, 0.25 mmol),The catalyst E (0.38 mg, OOl mmol),Benzyl acetate (0. 7508 g, 5 mmol, S / C = 10000: 1),Solvent dioxane (2.5 mL),The above reaction system was placed in a high-pressure reactor, Replacement of hydrogen three times,Charged with hydrogen gas of 50 atm,The reaction vessel was placed in a 80 C oil bath,Heating and stirring 16h,The reaction vessel was cooled in an ice bath.The reaction system was analyzed by gas chromatography (SPBTM-5, FUSEDSILICA Capillary Column, 30mX0.25mmX0.25ym, filmthickness)Injection temperature of 250 C,Detection temperature 260 C, program temperature 120 C (0 C) -20 C / min to 240 C (Omin). Gas chromatographic analysis yielded 82%.

The synthetic route of 140-11-4 has been constantly updated, and we look forward to future research findings.

Reference:
Patent; WUHAN KAITE LISI TECHNOLOGY CO LTD; Zhang, Xumu; Tan, xuefeng; (15 pag.)CN104387418; (2016); B;,
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

These common heterocyclic compound, 140-11-4, name is Benzyl acetate, its traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc, below Introduce a new synthetic route. Quality Control of Benzyl acetate

General procedure: Bioreactor cultures and biotransformations using E. coli JM109(pDTG601). Growth and biotransformation in the bioreactor usingE.coli JM109 (pDTG601) were carried out using a modification ofour previously published procedure.3b Thus, 5 mL of LB mediumsupplemented with ampicillin sodium salt (0.1 g/L) and glucose(5 g/L) were inoculated with a single colony of E. coli JM109(pDTG601), and grown overnight at 37 C and 150 rpm. Two500 mL shake-flasks containing 150 mL of MSB medium wereinoculated with 1 mL of the grown culture. These precultureflasks were placed in an orbital shaker at 37 C and 150 rpm, for12 hrs. Both entire cultures were used to inoculate the bioreactor(Sartorius Biostat A plus), charged with an initial volume of 2.5 L,and set to 500 rpm, 30 C, and air flow rate of 4L/min. The pHvalue was controlled automatically to 6.8 by addition of conc.ammonium hydroxide during the whole process. A pulse ofantifoam agents (Aldrich?s Antifoam Y: Silicone dispersion inwater 1:1) was added at the beginning of the run. At 6 h afterinoculation the dissolved oxygen value sharply increased(indicating carbon deprivation), whereupon a glucose fed-batchwas started by adding glucose (0.7 g/mL solution) from an initialrate of 0.08 mL/min to 0.54 mL/min in a 20 h period. When thebiomass concentration reached 15 g/L cdw, IPTG was added toinduce toluene dioxygenase expression (IPTG final concentrationin bioreactor of 10 mg/L), and the stirrer speed was set to900 rpm. After the culture reached the stationary phase (c.a.26 h, 50 g/L cdw aprox), glucose feeding was decreased to0.25 mL/min and substrate addition was started. A solution of thecorresponding substrate in liquid paraffin (0.5 M) was added at aflow rate of 20 mL/min using a peristaltic pump. After thebiotransformation was completed, the pH of the medium in thebioreactor was adjusted to 7.5. The culture broth was centrifugedat 7000 rpm and 4 C for 30 min, the supernatant was collectedand the cell pellet properly disposed. Centrifugation led to theseparation of the liquid paraffin (which contains no detectableamounts products) from the aqueous phase. The latter wasproperly lyophilized overnight to obtain a dry powder, whichwas extracted several times with ethyl acetate until no morediols were detected by TLC. The solvent was evaporated to affordthe corresponding diol, which was washed several times withhexanes to remove the liquid paraffin traces.

The synthetic route of Benzyl acetate has been constantly updated, and we look forward to future research findings.

Reference:
Article; Pazos, Mariana; Martinez, Sebastian; Vila, Maria Agustina; Rodriguez, Paola; Veiga, Nicolas; Seoane, Gustavo; Carrera, Ignacio; Tetrahedron Asymmetry; vol. 26; 24; (2015); p. 1436 – 1447;,
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

140-11-4, Name is Benzyl acetate, molecular formula is C9H10O2, Product Details of 140-11-4, belongs to esters-buliding-blocks compound, is a common compound. In a patnet, author is Leong, Huey Sze, once mentioned the new application about 140-11-4.

Monitoring metabolism of synthetic cannabinoid 4F-MDMB-BINACA via high-resolution mass spectrometry assessed in cultured hepatoma cell line, fungus, liver microsomes and confirmed using urine samples

Purpose A tert-leucinate derivative synthetic cannabinoid, methyl (2S)-2-([1-(4-fluorobutyl)-1H-indazole-3-carbonyl]amino)-3,3-dimethylbutanoate (4F-MDMB-BINACA, 4F-MDMB-BUTINACA or 4F-ADB) is known to adversely impact health. This study aimed to evaluate the suitability of three different modes of monitoring metabolism: HepG2 liver cells, fungus Cunninghamella elegans (C. elegans) and pooled human liver microsomes (HLM) for comparison with human in-vivo metabolism in identifying suitable urinary marker(s) for 4F-MDMB-BINACA intake. Methods Tentative structure elucidation of in-vitro metabolites was performed on HepG2, C. elegans and HLM using liquid chromatography-tandem mass spectrometry and high-resolution mass spectrometry analysis. In-vivo metabolites obtained from twenty authentic human urine samples were analysed using liquid chromatography-Orbitrap mass spectrometry. Results Incubation with HepG2, C. elegans and HLM yielded nine, twenty-three and seventeen metabolites of 4F-MDMB-BINACA, respectively, formed via ester hydrolysis, hydroxylation, carboxylation, dehydrogenation, oxidative defluorination, carbonylation or reaction combinations. Phase II metabolites of glucosidation and sulfation were also exclusively identified using C. elegans model. Eight in-vivo metabolites tentatively identified were mainly products of ester hydrolysis with or without additional dehydrogenation, N-dealkylation, monohydroxylation and oxidative defluorination with further oxidation to butanoic acid. Metabolites with intact terminal methyl ester moiety, i.e., oxidative defluorination with further oxidation to butanoic acid, were also tentatively identified. Conclusions The in-vitro models presented proved useful in the exhaustive metabolism studies. Despite limitations, HepG2 identified the major 4F-MDMB-BINACA ester hydrolysis metabolite, and C. elegans demonstrated the capacity to produce a wide variety of metabolites. Both C. elegans and HLM produced all the in-vivo metabolites. Ester hydrolysis and ester hydrolysis plus dehydrogenation 4F-MDMB-BINACA metabolites were recommended as urinary markers for 4F-MDMB-BINACA intake.

We’ll also look at important developments in the pharmaceutical industry because understanding organic chemistry is important in understanding health, medicine, 140-11-4. The above is the message from the blog manager. Product Details of 140-11-4.

Chemistry is an experimental science, Application In Synthesis of Benzyl acetate, and the best way to enjoy it and learn about it is performing experiments.Introducing a new discovery about 140-11-4, Name is Benzyl acetate, molecular formula is C9H10O2, belongs to esters-buliding-blocks compound. In a document, author is Al-Amrousi, Eslam F..

Production of Pure Biofuel and Some Chemicals From Waste Soap Stock

The non-esculent soap stock oil was employed for producing some rare chemicals, along with certain fractions of biofuels akin to those engendered from petroleum sources. This inexpensive feed stock was hydrotreated using NiMo/Al2O3 in the sulfided form as a catalyst. The applied process was accomplished in a continuous micro-reactor, under high pressure of hydrogen. The hydroprocessed oil was treated chemically for separating its liquid hydrocarbons from the fatty acid constituents. The fatty acids were esterified to be transformed to the corresponding methyl ester. The products were identified via the gas chromatographic technique. The results reflect that the acquired hydrocarbons are clean and free from oxygenated compounds, in addition to sulfur, which has an adverse impact on the environment and on the performance of engines, so it can be used as a high – grade biofuel and also as pure chemicals. Furthermore, the prepared fatty acids are characterized by their low molecular weight, with carbon numbers in the range of C-5 to C-22, including those with odd carbon numbers that regarded as very rare components in nature. Hence this work offers the ability for obtainment precious products from a cheap material.

Sometimes chemists are able to propose two or more mechanisms that are consistent with the available data. If a proposed mechanism predicts the wrong experimental rate law, however, the mechanism must be incorrect.Welcome to check out more blogs about 140-11-4, in my other articles. Application In Synthesis of Benzyl acetate.

The reaction rate of a catalyzed reaction is faster than the reaction rate of the uncatalyzed reaction at the same temperature. Recommanded Product: Benzyl acetate, 140-11-4, Name is Benzyl acetate, SMILES is CC(OCC1=CC=CC=C1)=O, in an article , author is Bui, Van-Muoi, once mentioned of 140-11-4.

Two new phenolic compounds from the Vietnamese lichen Parmotrema tinctorum

Chemical investigation of the lichen Parmotrema tinctorum (Nyl.) Hale led to the isolation of two new phenolic compounds, 2-ethylhexyl orsellinate (1) and tinctorinone (2). The structures were determined by analysis of their MS and NMR data as well as by comparison with literature data. The 2-ethylhexyl ester group of 2-ethylhexyl orsellinate is uncommon among lichen metabolites. Tinctorinone revealed strong inhibition towards alpha-glucosidase.

But sometimes, even after several years of basic chemistry education, it is not easy to form a clear picture on how they govern reactivity! 140-11-4, you can contact me at any time and look forward to more communication. Recommanded Product: Benzyl acetate.

One of the major reasons for studying chemical kinetics is to use measurements of the macroscopic properties of a system, such as the rate of change in the concentration of reactants or products with time. 140-11-4, Name is Benzyl acetate, formurla is C9H10O2. In a document, author is Zhang, Yujia, introducing its new discovery. Quality Control of Benzyl acetate.

Development and validation of samples stabilization strategy and LC-MS/MS method for simultaneous determination of clevidipine and its primary metabolite in human plasma: Application to clinical pharmacokinetic study in Chinese healthy volunteers

A feasible LC-MS/MS method with reliable stabilizers consisted of sodium fluoride, ascorbic acid and formic acid was developed and validated for the determination of clevidipine and its primary metabolite (H152/81) in human plasma. Sodium fluoride existing in the vacutainer tubes was used to inhibit esterase activity to protect the clevidipine from hydrolysis as soon as blood was collected. Ascorbic acid and formic acid were added to the separated plasma samples to avoid the oxidation and further hydrolysis of clevidipine and H152/81. The further sample preparation was accomplished through a single step liquid-liquid extraction (LLE) by ethyl acetate. The chromatography separation was carried out on an ACE Excel 3 mu m SuperC18 (2.1 x 50 mm, id, ACE, United Kingdom) column with gradient elution using 10 mM ammonium acetate water solution and methanol as the mobile phase. Detection was performed in the negative ion electrospray ionization mode using multiple reaction monitoring (clevidipine: m/z 454.1 -> 234.0; clevidipine-d7: m/z 461.1 -> 240.1; H152/81: m/z 354.0 -> 208.0; H152/81-13CD3: m/z 358.0 -> 212.0). The method exhibited good linearity over the concentration ranges of 0.100 to 40.0 ng/mL for clevidipine and 5.00 to 400 ng/mL for H152/81. The intraand inter-batch precision and accuracy of clevidipine and H152/81 were all within the acceptable criteria. The method was successfully applied to a pharmacokinetic study of clevidipine and H152/81 in healthy Chinese volunteers following 8 mg/h intravenous infusion of clevidipine butyrate injectable emulsion for 0.5 h. The results showed that clevidipine was rapidly eliminated with a short half-life time of 0.244 +/- 0.125 h and a maximum concentration of 25.2 +/- 7.09 ng/mL. H152/81 was detectable in the plasma samples up to 48.5 h with a half-life time of 10.7 +/- 2.30 h and a maximum plasma concentration of 301 +/- 38.1 ng/mL.

If you are hungry for even more, make sure to check my other article about 140-11-4, Quality Control of Benzyl acetate.

Application of 140-11-4, The transformation of simple hydrocarbons into more complex and valuable products via catalytic C–H bond functionalisation has revolutionised modern synthetic chemistry. 140-11-4, Name is Benzyl acetate, SMILES is CC(OCC1=CC=CC=C1)=O, belongs to esters-buliding-blocks compound. In a article, author is Deng, Qingsong, introduce new discover of the category.

Selective Synthesis of Benzothiophene-Fused Polycyclic, Eight-Membered N-Heterocycles via Amine-Mediated Three-Component Domino Strategy

A product-selective strategy was used to synthesize benzothiophene-fused polycyclic, eight-membered N-heterocycles via a three-component domino reaction of thioisatins under catalyst-free conditions. The reaction between tryptamine, thioisatin, and bromoacetophenone produced benzothiophene-fused polycyclic compounds. In contrast, using D-tryptophan methyl ester hydrochloride instead of tryptamine afforded benzothiophene-fused eight-membered N-heterocycles. DFT calculations showed that the benzothiophene-fused polycyclic compounds formed via the Pictet-Spengler reaction. However, the ester group in D-tryptophan methyl ester hydrochloride changed the reaction pathway and produced benzothiophene-fused eight-membered N-heterocycles.

Application of 140-11-4, One of the oldest and most widely used commercial enzyme inhibitors is aspirin, which selectively inhibits one of the enzymes involved in the synthesis of molecules that trigger inflammation. you can also check out more blogs about 140-11-4.

Chemistry is the experimental science by definition. We want to make observations to prove hypothesis. For this purpose, we perform experiments in the lab. , Application In Synthesis of Benzyl acetate, 140-11-4, Name is Benzyl acetate, molecular formula is C9H10O2, belongs to esters-buliding-blocks compound. In a document, author is Loukhmas, Sarah, introduce the new discover.

Assessment of Minerals, Bioactive Compounds, and Antioxidant Activity of Ten Moroccan Pomegranate Cultivars

The attractiveness of pomegranate (Punica granatum L.) is increasing worldwide among producers and consumers. Depending on its characteristics, the pomegranate may be intended for fresh consumption, for industrial processing, or for medical purposes. This study aims to assess the variability in terms of mineral content and biochemical properties of ten selected pomegranate cultivars grown in the center of Morocco to better know their fruit potential. Mineral composition, organic acids, total polyphenols, anthocyanins content, individual phenolic compounds, and antioxidant activity were determined in pomegranate juices. Results showed significant differences between cultivars. The sour cultivar Lhamdha is rich in organic acids, gallagyl esters, and ellagitannins and showed high antioxidant activity. It could therefore be used as a source for nutraceutical substances. The cultivar Sefri of Lalla Takerkoust showed important content of mineral elements, especially iodine (I), calcium (Ca), magnesium (Mg), iron (Fe), and silver (Ag). The cultivars Sefri of Ouled Abdellah, Sefri of Beni Meskine, Lahmer, and Marrakchia are suitable for production of fresh pomegranate juice with high potential of health benefits. In fact, they are rich in anthocyanins, polyphenols, and oxalic and ascorbic acids and they presented high antioxidant activity. While the cultivars Sefri of Sour Laaz, Sefri of Tmassine, Sefri of Sidi Abdellah, and Bzeq Tir could be intended for fresh fruit consumption. Cluster analysis has revealed the divergence of cultivars with the same appellation Sefri confirming the problem of homonymy or synonymy in the pomegranate cultivars appellation. This study clearly demonstrates the nutritional and functional potential of the studied cultivars and the importance of their valorisation, especially for food and pharmaceutical industries.

A reaction mechanism is the microscopic path by which reactants are transformed into products. Each step is an elementary reaction. In my other articles, you can also check out more blogs about 140-11-4. Application In Synthesis of Benzyl acetate.