Category: 140-11-4

Sun, Huahua published the artcileMutagenesis of the orco odorant receptor co-receptor impairs olfactory function in the malaria vector Anopheles coluzzii, Name: Benzyl acetate, the main research area is Anopheles coluzzii orco odorant receptor mutagenesis olfactory function; Anopheles coluzzii; CRISPR/Cas9; Host seeking; Odorant receptor co-receptor; Olfaction; Oviposition.

Mosquitoes rely heavily on their olfactory systems for host seeking, selection of oviposition sites, and avoiding predators and other environmental dangers. Of these behaviors, the preferential selection of a human blood-meal host drives the vectorial capacity of anthropophilic female Anopheles coluzzii mosquitoes. Olfactory receptor neurons (ORNs) are dispersed across several appendages on the head and express an obligate odorant receptor co-receptor (Orco) coupled with a ”tuning” odorant receptor (OR) to form heteromeric, odor-gated ion channels in the membrane of these neurons. To examine the mechanistic and functional contributions of Orco/OR complexes to the chemosensory processes of An. coluzzii, we utilized CRISPR/Cas9 gene editing to create a line of homozygous, Orco-knockout, mutant mosquitoes. As expected, orco-/- ORNs across both adult and larval stages of An. coluzzii display significantly lower background activity and lack nearly all odor-evoked responses. In addition, blood-meal-seeking, adult female, orco-/- mutant mosquitoes exhibit severely reduced attraction to human- and non-human-derived odors while gravid females are significantly less responsive to established oviposition attractants. These results reinforce observations in other insects that Orco is crucial in maintaining the activity of ORNs. In that light, it significantly influences a range of olfactory-driven behaviors central to the anthropophilic host preference that is critical to the vectorial capacity of An. coluzzii as a primary vector for human malaria.

Insect Biochemistry and Molecular Biology published new progress about Adult, nonmammalian. 140-11-4 belongs to class esters-buliding-blocks, name is Benzyl acetate, and the molecular formula is C9H10O2, Name: Benzyl acetate.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Qian, Yichun published the artcileCompletion of the cytosolic post-chorismate phenylalanine biosynthetic pathway in plants, Category: esters-buliding-blocks, the main research area is Petunia Arabidopsis cytosol chorismate mutase phenylalanine phenylpyruvate biosynthesis.

In addition to being a vital component of proteins, phenylalanine is also a precursor of numerous aromatic primary and secondary metabolites with broad physiol. functions. In plants phenylalanine is synthesized predominantly via the arogenate pathway in plastids. Here, we describe the structure, mol. players and subcellular localization of a microbial-like phenylpyruvate pathway for phenylalanine biosynthesis in plants. Using a reverse genetic approach and metabolic flux anal., we provide evidence that the cytosolic chorismate mutase is responsible for directing carbon flux towards cytosolic phenylalanine production via the phenylpyruvate pathway. We also show that an alternative transcription start site of a known plastidial enzyme produces a functional cytosolic prephenate dehydratase that catalyzes the conversion of prephenate to phenylpyruvate, the intermediate step between chorismate mutase and phenylpyruvate aminotransferase. Thus, our results complete elucidation of phenylalanine biosynthesis via phenylpyruvate in plants, showing that this pathway splits from the known plastidial arogenate pathway at chorismate, instead of prephenate as previously thought, and the complete pathway is localized in the cytosol.

Nature Communications published new progress about Arabidopsis thaliana. 140-11-4 belongs to class esters-buliding-blocks, name is Benzyl acetate, and the molecular formula is C9H10O2, Category: esters-buliding-blocks.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Suklje, Katja published the artcileRegional Discrimination of Australian Shiraz Wine Volatome by Two-Dimensional Gas Chromatography Coupled to Time-of-Flight Mass Spectrometry, Formula: C9H10O2, the main research area is discriminant analysis Shiraz wine volatile GCxGC TOF MS; grapevine; maturity; site (soil × climate); terroir; volatiles.

Shiraz wine volatome from two different Australian GIs i.e. Orange and Griffith was compared using comprehensive GCxGC-TOF MS. Shiraz wines were made from grapes harvested in triplicates at two harvest dates from six vineyards in two GIs. A total of 133 compounds showed a significant trend between wines from cooler Orange, and warmer Griffith. Compounds associated with wines from cooler climate were grape derived volatiles, such as monoterpenes, sesquiterpenes, green leaf volatiles and some norisoprenoids. Fermentation derived compounds, such as esters and S-containing compounds showed no specific trend related to grape origin. In addition, wines could be also clearly separated according to the harvest date, irresp. of the climate, with C6 compounds, higher alc. acetates, and other esters contributing outmost to the differentiation of samples, whereas terpenoids and norisoprenoids did not have an influence. This study demonstrated plasticity of wine volatome related to grape origin and also maturity level (harvest date), irresp. of climate.

Journal of Agricultural and Food Chemistry published new progress about Acidity (titratable). 140-11-4 belongs to class esters-buliding-blocks, name is Benzyl acetate, and the molecular formula is C9H10O2, Formula: C9H10O2.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

de Castro, Antonio published the artcileEffect of Spanish-style processing steps and inoculation with Lactobacillus pentosus starter culture on the volatile composition of cv. Manzanilla green olives, Computed Properties of 140-11-4, the main research area is Lactobacillus fermentation volatile compound olive; Lactobacillus pentosus; Manzanilla cultivar; Processing; Table olives; Volatile composition.

The effects of the main steps of Spanish-style processing (alk. treatment and fermentation) on the volatile composition of cv. Manzanilla green olives were studied. Both spontaneous and controlled fermentations were considered. In the latter case, a Lactobacillus pentosus strain from green olive fermentation brine was used as starter culture. The volatile profile was determined by headspace solid-phase microextraction (HS-SPME) combined with gas chromatog.-mass spectrometry (GC-MS). Most of the volatile compounds detected in fresh olives decreased or were undetected after alk. treatment, while several compounds (mostly acetic acid, 2-methylbutanoic acid, and ethanol) were formed as a result of this treatment. Over 50 new volatile components, mostly esters and phenols, appeared as a result of fermentation The most outstanding finding was a considerable increase in 4-Et phenol (almost 100-fold increase) in inoculated olives compared to the uninoculated product. However, a sensory panel did not find significant differences in odor perception.

Food Chemistry published new progress about Acidity (titratable). 140-11-4 belongs to class esters-buliding-blocks, name is Benzyl acetate, and the molecular formula is C9H10O2, Computed Properties of 140-11-4.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Younis, Inas Youssef published the artcileBioactive metabolites of hass and reed avocados targeting methicillin-resistant Staphylococcus aureus enterotoxin-like X via molecular modeling and cytotoxicity assessments, Quality Control of 140-11-4, the main research area is antibacterial hass reed avocado metabolite MRSA enterotoxin cancer; Avocado; enterotoxin-like X; methicillin-resistant Staphylococcus aureus; molecular modelling; serine/threonine kinases proteins; solid phase extraction.

The aim of this study is to estimate the nutritive values, metabolites of Hass and Reed Avocado cultivars and evaluate their antimicrobial and anticancer activities. Hass was rich in water soluble vitamins, iron and calcium while, Reed contains more fat soluble vitamins. Benzaldehyde and Bu phenol derivatives were the major volatile components identified by solid phase extraction in Hass and Reed, resp. Naringenin and rutin were the major compounds identified in Hass and Reed by HPLC anal. resp. Hass showed a promising antimicrobial activity, especially, against Methicillin-Resistant S. aureus (MIC = 7.81 μg/mL). Two targets sites were selected to investigate the mechanism of action of Hass, Staphylococcal Enterotoxin-like X and Serine/threonine kinases Proteins (STK). Mol. docking demonstrated high binding affinity of naringenin towards Enterotoxin-like X. However, high levels of rutin in Reed might account for its cytotoxic activity against colorectal adenocarcinoma. Avocado extracts may be used for developing potential antibiotics.

Natural Product Research published new progress about Antibacterial agents. 140-11-4 belongs to class esters-buliding-blocks, name is Benzyl acetate, and the molecular formula is C9H10O2, Quality Control of 140-11-4.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Harnying, Wacharee published the artcileN-Heterocyclic Carbene/Carboxylic Acid Co-Catalysis Enables Oxidative Esterification of Demanding Aldehydes/Enals, at Low Catalyst Loading, Quality Control of 140-11-4, the main research area is ester preparation; aldehyde alc oxidative esterification heterocyclic carbene benzoic acid catalyst; acylation; carbenes; cooperative catalysis; esterification; oxidation.

The discovery that simple carboxylic acids, such as benzoic acid, boost the activity of N-heterocyclic carbene (NHC) catalysts in the oxidative esterification of aldehydes RCHO (R = heptan-3-yl, Ph, 1-[4-(propan-2-yl)phenyl]propan-2-yl, 6-methylhept-5-en-2-yl, etc.) was reported. A simple and efficient protocol for the transformation of a wide range of sterically hindered α- and β-substituted aliphatic aldehydes/enals, catalyzed by a novel and readily accessible N-Mes-/N-2,4,6-trichlorophenyl 1,2,4-triazolium salt, and benzoic acid as co-catalyst, was developed. A whole series of α/β-substituted aliphatic aldehydes/enals hitherto not amenable to NHC-catalyzed esterification could be reacted at typical catalyst loadings of 0.02-1.0 mol%. For benzaldehyde, even 0.005 mol% of NHC catalyst proved sufficient: the lowest value ever achieved in NHC catalysis. Preliminary studies point to carboxylic acid-induced acceleration of acyl transfer from azolium enolate intermediates as the mechanistic basis of the observed effect.

Angewandte Chemie, International Edition published new progress about Alcohols Role: RCT (Reactant), RACT (Reactant or Reagent). 140-11-4 belongs to class esters-buliding-blocks, name is Benzyl acetate, and the molecular formula is C9H10O2, Quality Control of 140-11-4.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Zhou, Han-Chen published the artcileLarge scale preparation, stress analysis, and storage of headspace volatile condensates from Jasminum sambac flowers, Application In Synthesis of 140-11-4, the main research area is Jasminum volatile; Floral volatile condensates; Jasminum sambac; Odor activity value: SPME; Storage; Volatile compounds.

In this study, a large-scale preparation of jasmine floral volatile condensate (FVC) was conducted using fresh flowers without any extraction solvent involvement. Condensate volatile profiles were compared to those of fresh flowers for their scent characteristics and ability to withstand manufacturing and storage. The FVC possessed a typical jasmine flower scent, a similar odor polygon shape and greatly enhanced odor intensity and character odorants linalool, indole, and Me anthranilate. In late August and Sept. in Fuzhou, China, the ratio of odor activity values for indole/linalool in FVCs was close to that of fresh flowers, indicating that these were suitable local harvest times for FVC preparation Room temperature storage for 30 mo dramatically reduced the abundance of potent odorants and FVC scent intensity, while cold temperature (4 °C) storage was able to maintain FVC clarity and scent intensity. Our findings should be helpful at improving FVC quantity, quality, and storage.

Food Chemistry published new progress about Essential oils Role: ANT (Analyte), ANST (Analytical Study). 140-11-4 belongs to class esters-buliding-blocks, name is Benzyl acetate, and the molecular formula is C9H10O2, Application In Synthesis of 140-11-4.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Piryaei, Marzieh published the artcileNew fiber coating with silica-coated γ-Fe2O3 nanoparticles for extraction and determination of volatile compounds of Ziziphora tenuior L., Recommanded Product: Benzyl acetate, the main research area is silica coated iron oxide nanoparticle volatile compound determination extraction.

The present study synthesized the silica-coated γ-Fe2O3 nanoparticles (NPs) with a large surface area and employed it as a novel fiber coating for extracting and determining volatile compounds from Ziziphora tenuior in a min. period of time without using solvents with head solid-phase microextraction The simplex approach was applied to optimize all parameters concurrently. Major optimized parameters include temperature, extraction time, and sample weight In optimal circumstances, the repeatability for one fiber (n=5) was at the range of 2.8-9.2 percent for the sample compounds, which is given as relative standard division (R.S.D. %). The approach suggested in this work provides advantages such as simple usage, short anal. time, cheaper equipment, high relative recovery, and fiber thermal stability compared to common anal. approaches. Our findings indicated that γ-Fe2O3@SiO2-PW fibers are appropriate for the HS-SPME anal. of essential oils.

Nanochemistry Research published new progress about Essential oils Role: ANT (Analyte), ANST (Analytical Study). 140-11-4 belongs to class esters-buliding-blocks, name is Benzyl acetate, and the molecular formula is C9H10O2, Recommanded Product: Benzyl acetate.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Li, Rui published the artcileCarbon-Sulfur Bond Formation: Tandem Process for the Synthesis of Functionalized Isothiazoles, Computed Properties of 140-11-4, the main research area is isothiazole preparation; aldehyde tert butanesulfinamide acetic anhydride tandem reaction.

In this paper, a new process for the construction of 3,4,5-substituted isothiazoles via reaction cascades including Pummerer-like rearrangement, nucleophilic condensation, and sulfenamide cyclization followed by concomitant elimination and dehydration under mild reaction conditions is reported. This process provides isothiazoles bearing fluorine and other functional groups in good to excellent yields from readily available starting materials.

Organic Letters published new progress about Aldehydes Role: RCT (Reactant), RACT (Reactant or Reagent). 140-11-4 belongs to class esters-buliding-blocks, name is Benzyl acetate, and the molecular formula is C9H10O2, Computed Properties of 140-11-4.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Zhang, Lumin published the artcileCarbene reactivity from alkyl and aryl aldehydes, Product Details of C9H10O2, the main research area is aldehyde carbene reactivity chemoselective diastereoselective dimerization coupling heterocyclization deoxygenation; insertion ring expansion rearrangement.

Common aldehydes were readily converted (via stable α-acyloxy halide intermediates) to electronically diverse (donor or neutral) carbenes to facilitate >10 reaction classes was reported. This strategy enabled safe reactivity of nonstabilized carbenes from alkyl, aryl and formyl aldehydes via zinc carbenoids. Earth-abundant metal salts [iron(II) chloride, cobalt(II) chloride, copper(I) chloride] were effective catalysts for these chemoselective carbene additions to σ and π bonds.

Science (Washington, DC, United States) published new progress about Aldehydes Role: RCT (Reactant), RACT (Reactant or Reagent). 140-11-4 belongs to class esters-buliding-blocks, name is Benzyl acetate, and the molecular formula is C9H10O2, Product Details of C9H10O2.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics