Category: 121129-31-5

On November 30, 1990, Eichinger, Peter C. H.; Hayes, Roger N.; Bowie, John H. published an article.SDS of cas: 121129-31-5 The title of the article was Anionic rearrangement in the gas phase. The collision-induced loss of carbon monoxide from deprotonated pyruvates and hydroxyacetates. And the article contained the following:

Deprotonated pyruvates and hydroxyacetates, upon collisional activation, undergo loss of CO by anionic rearrangement through alkoxycarbonyl ion complexes, e.g., -CH2COCO2Me �[(CH2CO)-CO2Me] �-(CH2CO2Me) + CO or [CH2CO)-CO2Me] �[MeO-(CH2CO)] + CO, and MeC(O-)HCO2Me �[(MeCHO)-CO2Me] �MeCH(OMe)O- + CO. Such processes have been substantiated by labeling (2H, 13C) and product-ion studies. The experimental process involved the reaction of Methyl 2-hydroxy-3,3-dimethylbutanoate(cas: 121129-31-5).SDS of cas: 121129-31-5

The Article related to rearrangement anion gas phase, collisional activation mass spectra pyruvate hydroxyacetate, Physical Organic Chemistry: Degradation Reactions, Including Mass Spectral Fragmentation and other aspects.SDS of cas: 121129-31-5

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

On June 30, 2015, Yang, Jianxin; Yin, Yunxing; He, Zhenmin; Ma, Li; Li, Xin; Zhang, Zhiliu; Lin, Xiaojuan; Ma, Rujia published an article.Quality Control of Methyl 2-hydroxy-3,3-dimethylbutanoate The title of the article was 2-Hydroxymalonitrile – A useful reagent for one-step synthesis of α-Hydroxy esters. And the article contained the following:

An efficient one-pot synthesis of α-hydroxy esters via the reaction of 2-hydroxymalonitrile with an aldehyde or a ketone was described. The experimental process involved the reaction of Methyl 2-hydroxy-3,3-dimethylbutanoate(cas: 121129-31-5).Quality Control of Methyl 2-hydroxy-3,3-dimethylbutanoate

The Article related to aldehyde ketone hydroxymalonitrile alc esterification, alpha hydroxy ester preparation, Benzene, Its Derivatives, and Condensed Benzenoid Compounds: Esters, Acyl Peroxides, Acyl Halides and other aspects.Quality Control of Methyl 2-hydroxy-3,3-dimethylbutanoate

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

On April 2, 2021, Zhang, Zhihu; Tang, Zheng; Wang, Hao; Gao, Sen; Cui, Chaohui published a patent.HPLC of Formula: 121129-31-5 The title of the patent was Preparation of 3,3-dimethyl-2-oxobutanoic acid and its sodium salt. And the patent contained the following:

The invention relates to preparation of sodium 3,3-dimethyl-2-oxobutanoate and its sodium salt, which has the advantages of environmental friendliness and stability. The 3,3-dimethyl-2-oxobutyric acid and sodium salt thereof were prepared by the following steps: oxidation of sodium 2-hydroxy-3,3-dimethylbutanoate and sodium chlorite to obtain sodium 3,3-dimethyl-2-oxobutanoate; (2) acidification sodium 3,3-dimethyl-2-oxobutanoate to obtain free acid. The experimental process involved the reaction of Methyl 2-hydroxy-3,3-dimethylbutanoate(cas: 121129-31-5).HPLC of Formula: 121129-31-5

The Article related to preparation dimethyloxobutanoic acid sodium oxidation acidification, Aliphatic Compounds: Carboxylic Acids and Peroxycarboxylic Acids and Their Sulfur-Containing Analogs and Salts and other aspects.HPLC of Formula: 121129-31-5

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Ross, Tina Morgan; Liu, Jin-Jun published an article in 2010, the title of the article was 2-Chloro-4,6-dimethoxypyrimidine.Related Products of 121129-31-5 And the article contains the following content:

Preparation, properties, handling and applications of 2-chloro-4,6-dimethoxypyrimidine as reagent in nucleophilic substitution, carbonylation, nitration, Pechmann condensation reaction, Tisler triazolopyrimidine cyclization, cross-coupling reactions have been reviewed. The experimental process involved the reaction of Methyl 2-hydroxy-3,3-dimethylbutanoate(cas: 121129-31-5).Related Products of 121129-31-5

The Article related to review chloro dimethoxypyrimidine nucleophilic substitution alkoxycarbonylation nitration suzuki miyaura, triazolopyrimidine ferrocene chiral phosphine triazine coumarin preparation review and other aspects.Related Products of 121129-31-5

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

On June 4, 1993, Wei, Yen; Bakthavatchalam, R.; Jin, Xian Ming; Murphy, Christopher K.; Davis, Franklin A. published an article.Synthetic Route of 121129-31-5 The title of the article was Effect of aggregation on stereochemistry and mechanism of asymmetric oxidation of the lithium enolate of methyl 3,3-dimethylbutanoate in the solid state and in solution. And the article contained the following:

Oxidation of the title enolate by enantiopure (camphorylsulfonyl)oxaziridines in THF afforded α-hydroxy ester with 53-73% ee, but the product from the solid state reactions was racemic. The results suggest that the enolate exists and reacts as an aggregate in the solid state reactions. The experimental process involved the reaction of Methyl 2-hydroxy-3,3-dimethylbutanoate(cas: 121129-31-5).Synthetic Route of 121129-31-5

The Article related to asym oxidation lithium enolate mechanism, enantiopure camphorylsulfonyloxaziridine oxidation lithium enolate, stereoselective oxidation lithium enolate, solid state oxidation lithium enolate and other aspects.Synthetic Route of 121129-31-5

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Kirby, Gordon W.; Nazeer, Muhammad published an article in 1988, the title of the article was Asymmetric induction in the Diels-Alder reactions of α-hydroxyacylnitroso compounds.Recommanded Product: Methyl 2-hydroxy-3,3-dimethylbutanoate And the article contains the following content:

Transient, chiral α-hydroxyacylnitroso compounds, RCH(OR1)CONO (R = Ph, R1 = OH, OMe; R = CMe3, cyclohexyl, R1 = OH), form intramol. hydrogen bonds, react stereoselectively with cyclopentadiene and cyclohexa-1,3-diene to yield the cycloadducts I and II. The cycloadduct of cyclohexadiene and the nitroso derivative of (S)-mandelic acid has been converted into the known (-)-oxazine derivative III. The experimental process involved the reaction of Methyl 2-hydroxy-3,3-dimethylbutanoate(cas: 121129-31-5).Recommanded Product: Methyl 2-hydroxy-3,3-dimethylbutanoate

The Article related to hydroxyacylnitroso compound desls alder stereoselectivity, cyclopentadiene diels alder hydroxyacylnitroso compound stereochem, cyclohexadiene diels alder hydroxyacylnitroso compound stereochem, asym induction diels alder hydroxyacylnitroso compound, oxazine derivative and other aspects.Recommanded Product: Methyl 2-hydroxy-3,3-dimethylbutanoate

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

On April 2, 1999, Akazome, Motohiro; Takahashi, Toshiaki; Ogura, Katsuyuki published an article.Formula: C7H14O3 The title of the article was Enantiomeric Inclusion of α-Hydroxy Esters by (R)-(1-Naphthyl)glycyl-(R)-phenylglycine and the Crystal Structures of the Inclusion Cavities. And the article contained the following:

A simple dipeptide, (R)-(1-naphthyl)glycyl-(R)-phenylglycine [(R,R)-I], formed inclusion compounds with several α-hydroxy esters with high enantioselectivity. By crystallization of a mixture of the dipeptide I and racemic MeCH(OH)CO2Me [(RS)-II] from methanol, asym. recognition occurred to give an inclusion compound that contains S-II in 89% ee. X-ray crystallog. study of the inclusion compound elucidated that the dipeptide mols. arrange in a “folded antiparallel” β-sheetlike structure to accommodate the α-hydroxy ester in the pocket-type cavity surrounded by naphthyl and Ph groups on the sheet. Similarly, MeCH(OH)CO2Et and dihydro-3-hydroxy-4,4-dimethyl-2(3H)-furanone were included with high enantioselectivity of the S form. When bulkier Me3CCH(OH)CO2Me was used as a guest mol., the arrangement of dipeptide mols. changed to an “extended antiparallel” mode, where the naphthyl and Ph groups arranged in a “parallel stacked and displaced” mode and a channel-type cavity was constructed. The guest mols. were accommodated via hydrogen bonding in the channel-type cavity with high enantioselectivity of the S form (82% ee). In the case of Me2CHCH(OH)CO2Me [(RS)-III], optically pure (S)-III formed the dipeptide sheet with the “folded antiparallel” structure by cocrystn. with I, while the “extended antiparallel” structure appeared in the inclusion of (RS)-III. The experimental process involved the reaction of Methyl 2-hydroxy-3,3-dimethylbutanoate(cas: 121129-31-5).Formula: C7H14O3

The Article related to enantioselective inclusion hydroxy ester naphthylglycylphenylglycine, stereoselective crystallization hydroxy ester naphthylglycylphenylglycine, crystal structure hydroxy ester naphthylglycylphenylglycine inclusion complex, hydrogen bond hydroxy ester naphthylglycylphenylglycine inclusion complex and other aspects.Formula: C7H14O3

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics