Category: 121-79-9

Lu, Ting published the artcileImproving the oxidative stability of flaxseed oil with composite antioxidants comprising gallic acid alkyl ester with appropriate chain length, Recommanded Product: Propyl 3,4,5-trihydroxybenzoate, the publication is LWT–Food Science and Technology (2021), 110763, database is CAplus.

A gallic acid (GA) alkyl ester exerting the best antioxidant effect in flaxseed oil was identified from ten GA alkyl esters with various chain lengths, which was used in combination with other antioxidants including antioxidant of bamboo leaves, ascorbyl palmitate, butylated hydroxytoluene, phytic acid, phospholipid, rosemary extract, tocopherol, tea polyphenols, and tea polyphenol palmitate (TPP) to improve oxidative stability of flaxseed oil. Rancimat induction period, peroxide value, thiobarbituric acid-reactive substances, and ESR assays indicate that myristyl gallate (GA-C14) was the best GA ester. The flaxseed oil containing GA-C14 and TPP demonstrated the best oxidative stability among all the composite antioxidants. Through optimizing the mixture ratio, the flaxseed oil containing 34.4 mg/kg GA-C14 and 480 mg/kg TPP showed the best oxidative stability. Its shelf life was predicted by an accelerated shelf life testing using the Arrhenius model, which was prolonged 4.83-fold compared to the control sample under 25 °C.

LWT–Food Science and Technology published new progress about 121-79-9. 121-79-9 belongs to esters-buliding-blocks, auxiliary class Natural product, name is Propyl 3,4,5-trihydroxybenzoate, and the molecular formula is C10H12O5, Recommanded Product: Propyl 3,4,5-trihydroxybenzoate.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Sharma, Amit Kumar published the artcileProduction of a sustainable fuel from microalgae Chlorella minutissima grown in a 1500 L open raceway ponds, Application In Synthesis of 121-79-9, the publication is Biomass and Bioenergy (2021), 106073, database is CAplus.

Energy demand is increasing continuously due to the progress of industrialization, the vehicular population of the world, and modernization in lifestyle. In the present study, Chlorella minutissima microalgae were cultured in a 1500 L raceway open pond using com. fertilizer under semi-continuous mode. About 19.98 wt % lipid was extracted by the soxhlet extraction method from this microalgae biomass. To optimize the input reaction parameters (temperature, lipid to methanol ratio, microwave power, and reaction time) for improving transesterification yield, Response Surface Methodol. (RSM) was employed. The output responses of the experiments were biodiesel yield along with d., kinematic viscosity, calorific value, cold flow properties, and oxidation stability. To validate the model, confirmation trials were carried out. All the fuel properties were found to be satisfying ASTM D6751 and EN 14214 standard specifications except for oxidation stability at 3.0 h. The oxidation stability was further improved by using appropriate antioxidants and improved up to 10.5 h with the addition of 1000 ppm Pr gallate.

Biomass and Bioenergy published new progress about 121-79-9. 121-79-9 belongs to esters-buliding-blocks, auxiliary class Natural product, name is Propyl 3,4,5-trihydroxybenzoate, and the molecular formula is C10H11N3O3S, Application In Synthesis of 121-79-9.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Guldberg, T. S. published the artcileAnalysis of synthetic antioxidants in salmon silage using QuEChERS extraction method followed by determination by LC-MS/MS; a single-laboratory validation study, SDS of cas: 121-79-9, the publication is Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences (2021), 122715, database is CAplus and MEDLINE.

A new method was developed and inhouse validated to determined ethoxyquin (EQ), butylated hydroxyanisole (BHA) and Pr gallate (PG) in fish silage and fish oil used for production of animal feed. Sample pre-treatment comprises use of QuEChERS (quick, easy, cheap, effective, rugged and safe) extraction and gives extracts for liquid chromatog.-triple quadrupole mass spectrometry anal. without matrix interferences. The results allow quantification of the antioxidants in all matrixes by using deuterated internal standards and calibration curves made in solvent, as well as establishing low detection limits (0.012-0.015 mg/kg) and quantification limits (0.040-0.050 mg/kg) needed regarding the recent suspension of EQ as feed additive within the European Union. The proposed method was validated in terms of linearity, accuracy (relative error, ±1.4%), precision (RSD, â‰?.7%) and recovery (matrix effect, 97-101%) where all the parameters show acceptable results according to recognized guidelines (including EuraChem) within method validation. Combined expanded measurement uncertainty was estimated with a coverage factor of 2 by including all contributors to anal. variation, showing results of ±15% or better. The combined QuEChERS and LC-MS/MS method was successfully applied to salmon silage samples and their corresponding aqueous and oil fractions.

Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences published new progress about 121-79-9. 121-79-9 belongs to esters-buliding-blocks, auxiliary class Natural product, name is Propyl 3,4,5-trihydroxybenzoate, and the molecular formula is C10H12O5, SDS of cas: 121-79-9.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Tsukatani, Tadayuki published the artcileCombined effects of fumaric, lactic, and ferulic acid against food-borne pathogenic biofilms, Recommanded Product: Propyl 3,4,5-trihydroxybenzoate, the publication is Food Control (2022), 109024, database is CAplus.

In the present study, we selected food additives with potent biofilm eradication activities against food-borne pathogens. The min. biofilm eradication concentrations (MBECs) of 24 food additives against Escherichia coli and Staphylococcus aureus were estimated by a combined method of biofilm formation on the 96-pin microtiter plate lid, followed by a colorimetric microbial viability assay based on the reduction of tetrazolium salt. Fumaric acid alone demonstrated potent biofilm eradication activities against both E. coli and S. aureus. Furthermore, the combined effects of fumaric acid with other food additives against food-borne pathogenic biofilms were evaluated. Fumaric acid in combination with lactic acid and ferulic acid could effectively reduce the MBECs of a wide variety of food-borne bacteria. The selected combination was applied to the storage tests of fruit drinks and lightly pickled vegetables contaminated with biofilms. The findings of the present study revealed that the combination of fumaric acid, lactic acid, and ferulic acid can serve as an effective and safe inhibitor for use against biofilms by a wide variety of food-borne bacteria.

Food Control published new progress about 121-79-9. 121-79-9 belongs to esters-buliding-blocks, auxiliary class Natural product, name is Propyl 3,4,5-trihydroxybenzoate, and the molecular formula is C8H7NO4, Recommanded Product: Propyl 3,4,5-trihydroxybenzoate.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Kumar, Vinod published the artcileTuning Cationic Micelle Properties with an Antioxidant Additive: A Molecular Perspective, Application of Propyl 3,4,5-trihydroxybenzoate, the publication is Langmuir (2021), 37(15), 4611-4621, database is CAplus and MEDLINE.

In this work, we characterize the micellization and morphol. transition induced in aqueous cetyltrimethylammonium bromide (CTAB) solution by the addition of the antioxidant Pr gallate (PG) using tensiometry, rheol., and small-angle neutron scattering (SANS) techniques combined with the mol. dynamics (MD) simulation approach. The adsorption of CTAB at the air-water interface in the presence of varying [PG] revealed a progressive decrease in the critical micelle concentration (CMC), while the changes in different interfacial parameters indicated enhancement of the hydrophobicity induced by PG in the CTAB micellar system. The dynamic rheol. behavior indicated an increase in the flow viscosity (η) as a function of [PG]. Moreover, the rheol. components (storage modulus, G’, and loss modulus, G”) depicted the viscoelastic features. SANS measurements depicted the existence of ellipsoidal micelles with varying sizes and aggregation number (N_agg) as a function of [PG] and temperature Computational simulation performed using d. functional theory (DFT) calculations and mol. dynamics (MD) provided an insight into the at. composition of the examined system. The mol. electrostatic potential (MEP) anal. depicted a close proximity of CTAB, i.e., emphasized favorable interactions between the quaternary nitrogen of CTAB and the hydroxyl group of the PG monomer, further validated by the two-dimensional nuclear Overhauser enhancement spectroscopy (2D-NOESY), which showed the penetration of PG inside the CTAB micelles. In addition, various dynamic properties, viz., the radial distribution function (RDF), the radius of gyration (R_g), and solvent-accessible surface area (SASA), showed a significant microstructural evolution of the ellipsoidal micelles in the examined CTAB-PG system, where the changes in the micellar morphol. with a more elongated hydrophobic chain and the increased R_g and SASA values indicated the notable intercalation of PG in the CTAB micelles.

Langmuir published new progress about 121-79-9. 121-79-9 belongs to esters-buliding-blocks, auxiliary class Natural product, name is Propyl 3,4,5-trihydroxybenzoate, and the molecular formula is C10H12O5, Application of Propyl 3,4,5-trihydroxybenzoate.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Delfanian, Mojtaba published the artcileEffect of Steric Structure on the Mechanism of Antioxidant Activity of Alkyl Gallates in Soybean Oil Triacylglycerols-A Kinetic Approach, SDS of cas: 121-79-9, the publication is European Journal of Lipid Science and Technology (2021), 123(9), 2100019, database is CAplus.

From an interfacial phenomena standpoint, the effect of the alkyl chain length is evaluated on the mechanism of antioxidant activity of gallic acid ester derivatives (Me, Pr, octyl, dodecyl, and stearyl gallates) in bulk phase oil. A combinational kinetic model is used to estimate the oxidation kinetic parameters, such as induction period, the maximum concentration of lipid hydroperoxides, and critical reverse micelle concentration These kinetic parameters are estimated much better with the combinational model compared to the tangent method. The nonlinear behavior is observed for inhibitory activities of homologous series of antioxidants in soybean triacylglycerols. In terms of different kinetics parameters, including antioxidant effectiveness and activity, Me gallate has the highest inhibitory effect during lipid peroxidation Gallic acid and alkyl gallates are able to protect bulk oils against peroxidation (induction period > 336 h) in terms of the extent of their participation in the main reaction of chain termination and pro-oxidative side reactions of chain initiation, and anti-oxidative side reactions of chain propagation. This work explains the effect of the esterification in the inhibitory activity of alkyl gallates, mechanism action of alkyl gallates in bulk oil systems, antiradical potency as a function of the interfacial phenomena, and free radical chain mechanism, the impact of antioxidant activity on critical reverse micelle concentration of hydroperoxides. Moreover, in this study, it is confirmed that the combinational kinetic model can be employed as a reliable method for determining the oxidation kinetic parameters.

European Journal of Lipid Science and Technology published new progress about 121-79-9. 121-79-9 belongs to esters-buliding-blocks, auxiliary class Natural product, name is Propyl 3,4,5-trihydroxybenzoate, and the molecular formula is C10H12O5, SDS of cas: 121-79-9.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Soleimani, Adel published the artcileSynthesis, Characterization and Thermal Properties of Intrinsic Self-Healing Polyurethane Nanocomposites, Name: Propyl 3,4,5-trihydroxybenzoate, the publication is ChemistrySelect (2022), 7(16), e202103978, database is CAplus.

A hybrid thermo-reversible crosslinking polyurethane nanocomposite containing 0.5, 1, and 2 weight% of nano-silica was prepared with three intrinsic self-healing bonds (reversible covalent bonds supported by intrinsic hydrogen bonds and dangling chains). Owing to the introduction of pseudo-tannin and polyester diol that could form phenol-urethane networks and using nano-silica that causes dangling chains and hydrogen bonds, the prepared polyurethanes are capable of being reversed at 110°C and rejoin at low temperatures Thermoset self-healing polyurethane nanocomposites are prepared from pseudo-tannin, nano-silica, and a urethane-based prepolymer. The investigations of chem. structure, self-healing behavior, and crosslink network are carried out by Fourier Transform IR Spectroscopy (FTIR), Differential Scanning Calorimetry (DSC) technique, and swelling test. Dissociation of phenolic urethane at 110°C was confirmed by temperature variable FTIR. By swelling test, it was found that the self-healing polyurethane nanocomposites with 0.5 weight% of nano-silica have the most hard-domain, gel content, and crosslink d. in the samples. DSC technique shows that polyurethane samples have two heat transfer transitions (dangling chains and self-healing). Thermogravimetric anal. (TGA) findings show that nanocomposites decompose at elevated temperatures than neat PU, and the rate of degradation diminishes as silica content increases.

ChemistrySelect published new progress about 121-79-9. 121-79-9 belongs to esters-buliding-blocks, auxiliary class Natural product, name is Propyl 3,4,5-trihydroxybenzoate, and the molecular formula is C11H21BF4N2O2, Name: Propyl 3,4,5-trihydroxybenzoate.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Pechenov, Sergei published the artcileDevelopment of an orally delivered GLP-1 receptor agonist through peptide engineering and drug delivery to treat chronic disease, Safety of Propyl 3,4,5-trihydroxybenzoate, the publication is Scientific Reports (2021), 11(1), 22521, database is CAplus and MEDLINE.

Peptide therapeutics are increasingly used in the treatment of disease, but their administration by injection reduces patient compliance and convenience, especially for chronic diseases. Thus, oral administration of a peptide therapeutic represents a significant advance in medicine, but is challenged by gastrointestinal instability and ineffective uptake into the circulation. Here, we have used glucagon-like peptide-1 (GLP-1) as a model peptide therapeutic for treating obesity-linked type 2 diabetes, a common chronic disease. We describe a comprehensive multidisciplinary approach leading to the development of MEDI7219, a GLP-1 receptor agonist (GLP-1RA) specifically engineered for oral delivery. Sites of protease/peptidase vulnerabilities in GLP-1 were removed by amino acid substitution and the peptide backbone was bis-lipidated to promote MEDI7219 reversible plasma protein binding without affecting potency. A combination of sodium chenodeoxycholate and Pr gallate was used to enhance bioavailability of MEDI7219 at the site of maximal gastrointestinal absorption, targeted by enteric-coated tablets. This synergistic approach resulted in MEDI7219 bioavailability of ∼ 6% in dogs receiving oral tablets. In a dog model of obesity and insulin resistance, MEDI7219 oral tablets significantly decreased food intake, body weight and glucose excursions, validating the approach. This novel approach to the development of MEDI7219 provides a template for the development of other oral peptide therapeutics.

Scientific Reports published new progress about 121-79-9. 121-79-9 belongs to esters-buliding-blocks, auxiliary class Natural product, name is Propyl 3,4,5-trihydroxybenzoate, and the molecular formula is C10H12O5, Safety of Propyl 3,4,5-trihydroxybenzoate.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Nguyen Huu, Cuong published the artcileSynergistic inactivation of bacteria based on a combination of low frequency, low-intensity ultrasound and a food grade antioxidant, Application In Synthesis of 121-79-9, the publication is Ultrasonics Sonochemistry (2021), 105567, database is CAplus and MEDLINE.

This study evaluated a synergistic antimicrobial treatment using a combination of low frequency and a low-intensity ultrasound (LFU) and a food-grade antioxidant, Pr gallate (PG), against a model gram-pos. (Listeria innocua) and the gram-neg. bacteria (Escherichia coli O157:H7). Bacterial inactivation kinetic measurements were complemented by characterization of biophys. changes in liposomes, changes in bacterial membrane permeability, morphol. changes in bacterial cells, and intracellular oxidative stress upon treatment with PG, LFU, and a combination of PG + LFU. Combination of PG + LFU significantly (>4 log CFU/mL, P < 0.05) enhanced the inactivation of both L. innocua and E. coli O157:H7 compared to PG or LFU treatment. As expected, L. innocua had a significantly higher resistance to inactivation compared to E. coli using a combination of PG + LFU. Biophys. measurements in liposomes, bacterial permeability measurements, and scanning electron microscope (SEM)-based morphol. measurements show rapid interactions of PG with membranes. Upon extended treatment of cells with PG + LFU, a significant increase in membrane damage was observed compared to PG or LFU alone. A lack of change in the intracellular thiol content following the combined treatment and limited effectiveness of exogenously added antioxidants in attenuating the synergistic antimicrobial action demonstrated that oxidative stress was not a leading mechanism responsible for the synergistic inactivation by PG + LFU. Overall, the study illustrates synergistic inactivation of bacteria using a combination of PG + LFU based on enhanced membrane damage and its potential for applications in the food and environmental systems.

Ultrasonics Sonochemistry published new progress about 121-79-9. 121-79-9 belongs to esters-buliding-blocks, auxiliary class Natural product, name is Propyl 3,4,5-trihydroxybenzoate, and the molecular formula is C10H12O5, Application In Synthesis of 121-79-9.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Jain, Shubham published the artcilePassion fruit seed extract as an antioxidant additive for biodiesel; shelf life and consumption kinetics, Product Details of C10H12O5, the publication is Fuel (2021), 119906, database is CAplus.

One of the primary concerns in the use of biodiesel is its susceptibility towards radical-mediated oxidative reactions. The presence of unsaturated Me esters renders biodiesel vulnerable to oxidation It necessitates strategic interventions, which among a few others, includes the use of antioxidant additives. Natural antioxidants have multiple significant advantages over their synthetic counterparts. In the present study, the activity of methanolic passion fruit seed (PFS) extract as an antioxidant additive for waste cooking oil (soybean) biodiesel has been evaluated. The PFS extract contained a high proportion of phenolic compounds and exhibited excellent antiradical activity against model radical DPPH, which encouraged us to explore the case of unstable biodiesel further. At a concentration of 200 ppm, the PFS extract augmented the fuel’s resistance towards oxidation to levels where it could comply with European and the Indian specifications for blend-stock biodiesel. The performance of PFS extract was comparable to that of synthetic antioxidants, including butylated hydroxyanisole and butylated hydroxytoluene. The present study substantiates the utility of plant extracts rich in phenolics as an antioxidant additive for biodiesel.

Fuel published new progress about 121-79-9. 121-79-9 belongs to esters-buliding-blocks, auxiliary class Natural product, name is Propyl 3,4,5-trihydroxybenzoate, and the molecular formula is C10H12O5, Product Details of C10H12O5.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics