Category: 120157-98-4

Homma, Chihiro published the artcileSynthesis of alkynyl Z-ketimines and their application in amine-catalyzed asymmetric Mannich reactions and conjugate addition, Formula: C7H13NO3, the main research area is alkynyl ketimine amine catalyst enantioselective Mannich reaction conjugate addition.

A facile and practical synthesis of various alkynyl Z-ketimines, which was used as a synthetic equivalent of alkyl ketimines was developed. The obtained alkynyl Z-ketimines was successfully applied in enantioselective Mannich reaction and conjugate addition catalyzed by a chiral amine with an acid functionality.

Tetrahedron published new progress about Aldehydes Role: RCT (Reactant), RACT (Reactant or Reagent). 120157-98-4 belongs to class esters-buliding-blocks, name is tert-Butyl acetylcarbamate, and the molecular formula is C7H13NO3, Formula: C7H13NO3.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Wu, Liqiang published the artcileSilica sulfuric acid: a versatile and reusable heterogeneous catalyst for the synthesis of N-acyl carbamates and oxazolidinones under solvent-free conditions, Category: esters-buliding-blocks, the main research area is silica sulfuric acid versatile reusable heterogeneous catalyst; synthesis acyl carbamate oxazolidinone solvent free condition.

Silica sulfuric acid catalyzes efficiently the reaction of carbamates and oxazolidinones with anhydrides under solvent-free conditions. All the reactions were done at room temperature and the N-acyl carbamates and oxazolidinones were obtained with high yields and purity via an easy work-up procedure. This method is attractive and is in a close agreement with green chem.

Bulletin of the Chemical Society of Ethiopia published new progress about Anhydrides Role: RCT (Reactant), RACT (Reactant or Reagent). 120157-98-4 belongs to class esters-buliding-blocks, name is tert-Butyl acetylcarbamate, and the molecular formula is C7H13NO3, Category: esters-buliding-blocks.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Itoh, Akichika published the artcileOxidative photo-decarboxylation in the presence of mesoporous silicas, Application of tert-Butyl acetylcarbamate, the main research area is carbonyl compound preparation; mesoporous silica catalyst oxidative photodecarboxylation carboxylic acid.

FSM-16, a mesoporous silica, was found to catalyze oxidative photo-decarboxylation of α-hydroxy carboxylic acid, phenylacetic acid derivatives, and N-acyl-protected α-amino acids to afford the corresponding carbonyl compounds Furthermore, FSM-16 proved to be re-usable by re-calcination at 450°C after the reaction.

Chemical & Pharmaceutical Bulletin published new progress about Aldehydes Role: SPN (Synthetic Preparation), PREP (Preparation). 120157-98-4 belongs to class esters-buliding-blocks, name is tert-Butyl acetylcarbamate, and the molecular formula is C7H13NO3, Application of tert-Butyl acetylcarbamate.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Pollack, Scott R. published the artcileMetal-free stereoselective synthesis of (E)- and (Z)-N-monosubstituted β-aminoacrylates via condensation reactions of carbamates, Formula: C7H13NO3, the main research area is carbamate alkoxyacrylate acid catalyst metal free diastereoselective condensation reaction; dialkoxypropanoate carbamate acid catalyst metal free diastereoselective condensation reaction; propynoate carbamate base catalyst diastereoselective condensation reaction; aminoacrylate preparation stereoselective metal free.

Two efficient, stereoselective methods for the preparation of (E)- or (Z)-β-aminoacrylates via acid- or base-promoted condensation reactions of carbamates are described. The base-promoted reaction is E-selective, while acid catalysis can, through the choice of solvent, selectively form E or Z. The acid-catalyzed E-selective process proceeds through a crystallization obviating the need for chromatog. purification

Journal of Organic Chemistry published new progress about Amino esters Role: SPN (Synthetic Preparation), PREP (Preparation). 120157-98-4 belongs to class esters-buliding-blocks, name is tert-Butyl acetylcarbamate, and the molecular formula is C7H13NO3, Formula: C7H13NO3.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Sakai, Takeo published the artcileTotal Synthesis of Brevisamide Using an Oxiranyl Anion Strategy, Application In Synthesis of 120157-98-4, the main research area is brevisamide total synthesis coupling etherification hydrogenation; diastereoselective synthesis brevisamide; nucleophilic substitution total synthesis brevisamide; Horner Wadsworth Emmons total synthesis brevisamide.

A total synthesis of brevisamide, a marine monocyclic ether amide isolated from the dinoflagellate Karenia brevis, has been achieved in 18 steps starting from 4-(benzyloxy)butanol. The synthesis involves oxiranyl anion coupling between an epoxy sulfone and a triflate, intramol. etherification of a hydroxy-bromoketone, diastereoselective introduction of the axial Me group by hydroxyl-directed hydrogenation of an exocyclic olefin, and installation of an acetamide side chain by nucleophilic substitution of an N-acetyl carbamate. The dienal side chain is assembled using a Horner-Wadsworth-Emmons reaction to complete the synthesis.

Journal of Organic Chemistry published new progress about Coupling reaction. 120157-98-4 belongs to class esters-buliding-blocks, name is tert-Butyl acetylcarbamate, and the molecular formula is C7H13NO3, Application In Synthesis of 120157-98-4.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Singh, Om V. published the artcileIridium(I)-catalyzed regio- and enantioselective allylic amidation, Application In Synthesis of 120157-98-4, the main research area is iridium catalyst phosphoramidite ligand enantioselective regioselective allylic amidation carbonate; allylic amine protected asym preparation; amino acid preparation allylic amine oxidation; cytoxzone preparation methoxyphenylallylamine reactant.

Iridium(I)-catalyzed intermol. allylic amidation of Et allyl carbonates with soft nitrogen nucleophiles under completely ‘salt-free’ conditions is described. A combination of [Ir(COD)Cl]2 catalyst, chiral phosphoramidite I as a ligand, and DBU as a base in THF effects the reaction. For example, the allylic amidation of EtOCO2CH2CH:CHR (R = n-Pr, Ph) with NR1R2 (R1 = Ac, R2 = Boc; R1 = R2 = Boc; R1 = Cbz, R2 = Boc; R1 = R2 = Cbz) with catalyst [Ir(COD)Cl]2 and ligand I in presence of DBU in THF proceeded with excellent regio- and enantioselectivities to afford the branched N-protected allylic amines II. II (R = Ph) was converted to α-amino acid III in one step and to β-amino acid IV in two steps. Similarly, II (R = C6H4OMe-4) was conveniently used in the asym. synthesis of (-)-cytoxazone.

Tetrahedron Letters published new progress about Amidation (allylic). 120157-98-4 belongs to class esters-buliding-blocks, name is tert-Butyl acetylcarbamate, and the molecular formula is C7H13NO3, Application In Synthesis of 120157-98-4.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Shibata, Yoshihiro published the artcileSynthesis and structure-activity relationships of 2-aminoacetamide derivatives as peroxisome proliferator-activated receptor α/γ dual agonists, Application of tert-Butyl acetylcarbamate, the main research area is zwitterionic aminoacetamide preparation peroxisome proliferator activated receptor agonist antidiabetic.

The design, syntheses, and structure-activity relationships of novel zwitterionic compounds 2-aminoacetamides I [R = NH2, azetidinyl, piperidinyl, etc.; R1 = H, Me; R2 = H, Me] and II [R = NHC(O)Me, C(O)NHMe] as nonthiazolidinedione-based peroxisome proliferator-activated receptor (PPAR) α/γ dual agonists was described. Further optimization was also carried out to improve the stability while maintaining the other favorable profile features including potent PPARα/γ dual agonistic activity. The amide derivatives were stable in acidic conditions and decreased plasma glucose and plasma triglyceride levels significantly without marked weight gain.

Chemical & Pharmaceutical Bulletin published new progress about Amines Role: RCT (Reactant), RGT (Reagent), SPN (Synthetic Preparation), RACT (Reactant or Reagent), PREP (Preparation). 120157-98-4 belongs to class esters-buliding-blocks, name is tert-Butyl acetylcarbamate, and the molecular formula is C7H13NO3, Application of tert-Butyl acetylcarbamate.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Homma, Chihiro; Yamanaka, Masahiro; Kano, Taichi; Maruoka, Keiji published the artcile< Synthesis of alkynyl Z-ketimines and their application in amine-catalyzed asymmetric Mannich reactions and conjugate addition>, Computed Properties of 120157-98-4, the main research area is alkynyl ketimine amine catalyst enantioselective Mannich reaction conjugate addition.

A facile and practical synthesis of various alkynyl Z-ketimines, which was used as a synthetic equivalent of alkyl ketimines was developed. The obtained alkynyl Z-ketimines was successfully applied in enantioselective Mannich reaction and conjugate addition catalyzed by a chiral amine with an acid functionality.

Tetrahedron published new progress about Aldehydes Role: RCT (Reactant), RACT (Reactant or Reagent). 120157-98-4 belongs to class esters-buliding-blocks, and the molecular formula is C7H13NO3, Computed Properties of 120157-98-4.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics