Category: 120-61-6

Reference of 120-61-6, These common heterocyclic compound, 120-61-6, name is Dimethyl terephthalate, its traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc, below Introduce a new synthetic route.

In the examples described below, the equipment used consisted of a one-liter base fitted with a heating mantel, magnetic stirrer bar, temperature sensor, and 10 Penn State-packed distillation column. The top of the column was fitted with a variable rate take-off head to allow selective removal of the methanol.Each example was run under typical reaction conditions by conducting the reaction at reflux while removing methanol via the packed column at a take-off ratio of 1:4. At the completion of the reaction, the excess alcohol was then stripped from the base after replacing the fractionating column with a 3 Vigreux column and applying vacuum to a final pressure of 18 mm Hg. The crude product was treated with 2.5% aqueous NaOH to neutralize the TIPT catalyst and washed twice with deionized water. The material was then suction filtered through a glass fiber filter circle coated with Dicalite filter-aid. The product was subsequently dried at a final base temperature of 120 C. at 1 mm Hg and held one hour. After cooling to 90 C., activated carbon (0.2 wt. %) was added and held at this temperature while stirring for one hour. The final product was isolate by filtration through a glass fiber filter coated with Dicalite filter-aid; The reaction was conducted in accordance with the chemical equation generally illustrated above on page 3 and was designed to produce a product derived from a 50:50 mole percent mixture of n-butanol and isobutanol.The reactor system was charged with 436.9 g (2.25 mol, MW=194.19) of dimethyl terephthalate, 207.5 g (2.8 mol, MW=74.12) of n-butanol, 207.5 g (2.8 mol, MW=74.12) of isobutanol and 223 ppm (0.19 g) of tetraisopropoxy titanate (TIPT). The reaction progress is summarized in the Table 1 below; The product was stripped as summarized in Table 2 below; After neutralization, drying, carbon treatment and final filtration in accordance with the above-describe general work-up procedure, the isolated product weighed 547.7 g. The theoretical amount of product is 626.28 g for an 87.5% isolated yield; The reaction described in Example 1 was repeated to produce a product derived from a 75:25 mole percent mixture of n-butanol and isobutanol, respectively. The reactor system was charged with 233 g (1.2 mol, MW=194.19) of dimethyl terephthalate, 200.1 g (2.78 mol, MW=74.12) of n-butanol, 66.7 g (0.9 mol, MW=74.12) of isobutanol and 220 ppm (0.11 g) of TIPT. The reaction progress is summarized in the Table 3 below; The product was stripped as summarized in Example 1 above and isolated as a clear liquid after neutralization, drying, carbon treatment and final filtration; The reaction described in Example 1 was repeated to produce a product derived from a 25:75 mole percent mixture of n-butanol and isobutanol, respectively. The reactor system was charged with 233 g (1.2 mol, MW=194.19) of dimethyl terephthalate, 66.7 g (0.9 mol, MW=74.12) of n-butanol, 200.1 g (2.7 mol, MW=74.12) of isobutanol and 280 ppm (0.14 g) of TIPT. The reaction progress is summarized in the Table 4 below; The product was stripped as summarized in Example 1 above and isolated as a partially solid material after neutralization, drying, carbon treatment and final filtration. Since the goal was to develop lower freezing products, no further work was done with this material.Each sample was analyzed by capillary gas chromatography (uncorrected area percent values reported). The results are summarized in Table 5 below; Two of the above materials (158-01, 163-01) along with pure DBT were submitted for a DSC point study. This study incorporated heat-cool-heat cycles in an hermetically sealed stainless steel pan. The scan rate was 2 C./min. in helium. FIG. 1 is the warm-up cycle for pure DBT.The results show a complex freezing point behavior. For the 75:25 DBT/DIBT mixture:1. On the first warm-up, there are two crystallization events at -66 and -42 followed by a minor melting event at -5 and a major one at 6.2. On the second warm-up, it goes through two crystallization events at -35 and -29 followed by a minor melting event at -5 and a major one at 6.3. The freezing point peaked at around -42 (super cooled).For the 50:50 mixture:1. The freezing point peaked at around -22 C. (super cooled).2. On the first warm-up it goes through two low-temperature events: crystallized at -56 and melted at -17 followed with another melting at -6 and a final melting event at 8.3. On the second warm-up, it goes through one crystallization event at -15 and one melt event at -8 followed with a minor melting event at 10.Of the two, the 50:50 looks the best in that there is a smaller melting event at the warmer region (minor at 8-10 vs. major at 6 for 75:25). On the other hand, the 75:25 seems to super cool to a lower temperature than the 50:50 (-42 vs. -22).Note that the DBT super cooled to -7 before freezing, as shown in FIG. 5

The synthetic route of 120-61-6 has been constantly updated, and we look forward to future research findings.

Reference:
Patent; Eastman Chemical Company; US7361779; (2008); B1;,
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 120-61-6, name is Dimethyl terephthalate belongs to esters-buliding-blocks compound, it is a common compound, a new synthetic route is introduced below. Recommanded Product: Dimethyl terephthalate

Dimethyl terephthalate (h) 10g (51. 5mmol) ethanol, 15 ml, is dissolved in a mixed solvent of chloroform 10 ml, hydrate alkylhydrazine 1 25 therein. Adding 8g (515mmol), 4 is made to circulate heating time. After cooling, the solid is separated by filtration in a reaction solution, using ethanol 10 ml, filter to 2 times after washing, drying under reduced pressure, 10g of compound (i) is obtained.

The synthetic route of 120-61-6 has been constantly updated, and we look forward to future research findings.

Reference:
Patent; JNC Corporation; Sasada, Yasuyuki; Minowa, Tetsuharu; (45 pag.)JP5664479; (2015); B2;,
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Electric Literature of 120-61-6, A common heterocyclic compound, 120-61-6, name is Dimethyl terephthalate, molecular formula is C10H10O4, its traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc, below Introduce a new synthetic route.

The synthetic procedure of the probe is illustrated in the Scheme 1. Methanolic solution (10 ml) of terephthalic acid in the presence of con.H2SO4 (10:1) was refluxed for 6 h. The reaction mixture was cooled to room temperature and evaporated under pressure, provided a dirty white colour solid. The solid formed was extracted with DCM for at least 3 times in order to completely remove the impurities and dried using MgSO4. The solution was then filtered and evaporated to give milky white solid (1 mmol). Subsequently, it was re-dissolved in methanol followed by slow addition of hydrazine monohydrate (2 mmol) and allowed to reflux for 3 h. The obtained white solid (bis-hydrazine derivative) was filtered,washed with water and dried under vacuum. A hot-aqueous solution of bis-hydrazine derivative (1 mmol) was mixed dropwise with pyridine-2-aldehyde (2 mmol) and again refluxed at 80 C for2 h. The probe (BPTH) was obtained as a white puffy solid which was filtered and dried in vacuum.

The synthetic route of 120-61-6 has been constantly updated, and we look forward to future research findings.

Reference:
Article; Senthil Murugan, Arumugam; Abel Noelson, Enose Rajan; Annaraj, Jamespandi; Inorganica Chimica Acta; vol. 450; (2016); p. 131 – 139;,
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Electric Literature of 120-61-6, In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 120-61-6, name is Dimethyl terephthalate belongs to esters-buliding-blocks compound, it is a common compound, a new synthetic route is introduced below.

The reaction described in Example 1 was repeated, yielding the product from pure isobutyl alcohol.In a three-necked flask equipped with stirring blades0.3 mol of dimethyl terephthalate (DMT) was added,2 moles of isobutanol,The temperature was raised to 120 C,After the DMT was completely dissolved,17.46 g of Nafion resin was added,After the control reaction temperature between 127 ~ 137 ,So that the droplet dropping speed control in 3 to 6 drops per second,Every 7h add 2mol isobutanol,Add a total of two times,Reaction 21h after the end.After the ester interchange reaction is completed,The solid resin was filtered off,The crude product was then reactedWas added to the clean flask,And add a little porcelain pieces after vacuum distillation,Vacuum control in about 0.08MPa,Slowly increase the distillation temperature to no liquid drops,The distillation temperature did not exceed 142 C.The final product after vacuum distillation was analyzed by capillary gas chromatography,The composition is shown in Table 1 below.The isolated final product weighed 77.739 g,The theoretical amount of product was 83.50 g,The overall yield was therefore 93.1%

In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles, Dimethyl terephthalate, other downstream synthetic routes, hurry up and to see.

Reference:
Patent; Shanghai Huayi Energy Chemical Co., Ltd.; Xu, Yunfeng; Zhao, Zhengkang; Ma, Jinqiang; Chen, Chen; Cui, Yunhue; Tan, Dong; (10 pag.)CN105693519; (2016); A;,
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Related Products of 120-61-6,Some common heterocyclic compound, 120-61-6, name is Dimethyl terephthalate, molecular formula is C10H10O4, traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc, below Introduce a new synthetic route.

A solution of 4.01 g of dimethyl terephthalate in methanol and 42 g of a methanol solution of dimethyl terephthalate was prepared.0.4003 g of the activated-passivated nickel-containing catalyst and 0.8005 g of the copper-based catalyst were added and hydrogenation reaction was carried out at 200 C. under a hydrogen pressure of 4 MPa and stirring at 700 r/min for 4 h. The temperature was then raised to 240C, the hydrogen pressure was adjusted to 8 MPa, and the reaction was carried out for 4 hours while stirring at 700 r/min. After the reaction was cooled down to room temperature overnight, the catalyst was separated by centrifugation, filtration, and the solution was distilled to obtain 1,4-cyclohexanedimethanol product after purification. The yield was 92%.

These compound has a wide range of applications. It is believed that with the continuous development of the source of the synthetic route Dimethyl terephthalate, its application will become more common.

Reference:
Patent; Shandong Yuhuang Chemical Co., Ltd.; Yuan Benfu; Pang Fei; Guo Chunping; Xu Longkun; Wang Rongguang; Wang Hui; Wang Zhongya; Hou Hongxia; Wang Jianwei; Wang Shengwei; (6 pag.)CN107805183; (2018); A;,
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

A catalyst don’t appear in the overall stoichiometry of the reaction it catalyzes, but it must appear in at least one of the elementary reactions in the mechanism for the catalyzed reaction. 120-61-6, Name is Dimethyl terephthalate, molecular formula is C10H10O4. In an article, author is Wang, Hong-Yi,once mentioned of 120-61-6, Recommanded Product: Dimethyl terephthalate.

Development of a Novel Chemoenzymatic Process for (S)-1-(Pyridin-4-yl)-1,3-propanediol

We first developed a novel and efficient chemoenzymatic process to prepare (S)-1-(pyridin-4-yl)-1,3-propanediol, a vital HepDirect prodrug intermediate, from inexpensive and commercially available isonicotinic acid. Through this process, we provide a creative way to obtain the key chiral intermediate, beta-hydroxyester, with ketoreductase (KRED) EA. After optimization of the process, we performed the reaction on a 100 g scale with a substrate concentration of up to 150 g/L, a yield of 93%, and an ee value of up to 99.9%. Additionally, we used a simple and effective NaBH4/MgCl2 reduction system to obtain (S)-1-(pyridin-4-yl)-1,3-propanediol with >99.9% ee and an 80% yield. This novel chemoenzymatic process has the potential to be a cost-effective and environmentally friendly process suitable for industrial use.

Interested yet? Keep reading other articles of 120-61-6, you can contact me at any time and look forward to more communication. Recommanded Product: Dimethyl terephthalate.

Chemistry can be defined as the study of matter and the changes it undergoes. You’ll sometimes hear it called the central science because it is the connection between physics and all the other sciences, starting with biology. 120-61-6, Name is Dimethyl terephthalate, molecular formula is , belongs to esters-buliding-blocks compound. In a document, author is Tarpy, David R., Safety of Dimethyl terephthalate.

Influence of brood pheromone on honey bee colony establishment and queen replacement

There is both anecdotal and empirical evidence to suggest that honey bee queen longevity has decreased in recent years, leading to premature supersedure and queen failure. This is particularly evident when beekeepers create new colonies from packages, where many queens are immediately rejected or replaced after only a few weeks. Relatively little is known about the mechanisms that trigger supersedure in honey bees, although previous studies have shown a strong link with open brood suggesting that brood ester pheromone (BEP) may be involved. We installed new packages into hive equipment with either no treatment (Control), exposure to BEP during package transport and for the first 10 days after installation (BEP), or one frame of open brood (Brood). We found that over the course of the 12-week experiment, Control colonies grew the least, Brood colonies started stronger but leveled off similar to Control colonies, and BEP colonies grew slowly initially but continued positive growth through the end of the experiment. Moreover, we found a highly significant effect of treatment on Outcome-whether the initial queens were immediately Rejected (within 5 weeks), Superseded (after 5 weeks), or Accepted, with Brood, BEP, and Control colonies having 86.7%, 53.3%, and 33.3% acceptance, respectively. Finally, we found that the open-brood:adult-bees ratio significantly diverged 3 weeks prior to queen replacement between accepting and replacing colonies. We suggest that while BEP alone is insufficient to deter premature supersedure, there are clear benefits to queen longevity and package-installation success when establishing new colonies with frames of young brood.

Sometimes chemists are able to propose two or more mechanisms that are consistent with the available data. If a proposed mechanism predicts the wrong experimental rate law, however, the mechanism must be incorrect.Welcome to check out more blogs about 120-61-6, in my other articles. Safety of Dimethyl terephthalate.

Related Products of 120-61-6, Catalysts allow a reaction to proceed via a pathway that has a lower activation energy than the uncatalyzed reaction. 120-61-6, Name is Dimethyl terephthalate, SMILES is O=C(OC)C1=CC=C(C(OC)=O)C=C1, belongs to esters-buliding-blocks compound. In a article, author is Hayashi, Mikihiro, introduce new discover of the category.

Dominant Factor of Bond-Exchange Rate for Catalyst-Free Polyester Vitrimers with Internal Tertiary Amine Moieties

Catalyst-free vitrimers have attracted attention for practical application of the vitrimer concept, which requires fundamental knowledge of physical property tuning. We prepared catalyst-free vitrimers by cross-linking amorphous polyesters bearing COOH side groups with tetraepoxy compounds bearing tertiary amines (4,4′-methylenebis(N,N-diglycidylaniline), abbreviated as Mb-epoxy). The obtained network possessed ester and OH groups, and the amino moieties worked as internal catalysts for trans-esterification-based bond exchange. The competing effect of cross-link density and concentration of amines was investigated for samples with different fractions of Mbepoxy, revealing that cross-link density, which governs chain mobility, was the dominant factor in the determination of bond-exchange rate.

Related Products of 120-61-6, Each elementary reaction can be described in terms of its molecularity, the number of molecules that collide in that step. The slowest step in a reaction mechanism is the rate-determining step.you can also check out more blogs about 120-61-6.

Children learn through play, and they learn more than adults might expect. Science experiments are a great way to spark their curiosity, SDS of cas: 120-61-6120-61-6, Name is Dimethyl terephthalate, SMILES is O=C(OC)C1=CC=C(C(OC)=O)C=C1, belongs to esters-buliding-blocks compound. In a article, author is Nadirov, Kazim S., introduce new discover of the category.

Obtaining High-Paraffin-Content Oil Depressants

A depressor action composition was prepared for lowering the pour point of high-paraffin oils based on butanol and cotton soap stock fatty acids (FA), mainly a C16-C18 distillate fraction. The possibility of using cotton soap stock FA for their esterification with butyl alcohol and ester production based on them is shown. A scheme for preparing the depressor action reagent BEG-1 based on the esterified FA, monoethanolamine, and cotton soap stock is proposed. When the BEG was introduced into the samples of high-paraffin oil taken directly from the group metering device, a decrease in the paraffin crystal size and shape was observed, i.e. their almost complete dissolution, which was accompanied by a change in the viscosity of the samples. Compositions having high surface-active properties, thermodynamic resistance, and stability were prepared. The paraffin crystal morphology, crystal structure, and shape change were studied. The data obtained are of value for the pipeline transport of hydrocarbons, as the use of the proposed depressor action reagent for high-paraffin oils can significantly reduce the viscosity of the oil in the pipeline, helping to reduce the energy costs associated with heating the oil for its pumping.

Note that a catalyst decreases the activation energy for both the forward and the reverse reactions and hence accelerates both the forward and the reverse reactions. you can also check out more blogs about 120-61-6. SDS of cas: 120-61-6.

Chemistry is an experimental science, HPLC of Formula: C10H10O4, and the best way to enjoy it and learn about it is performing experiments.Introducing a new discovery about 120-61-6, Name is Dimethyl terephthalate, molecular formula is C10H10O4, belongs to esters-buliding-blocks compound. In a document, author is Qiu, Jiangbing.

Response of fatty acids and lipid metabolism enzymes during accumulation, depuration and esterification of diarrhetic shellfish toxins in mussels (Mytilus galloprovincialis)

Bivalve mollusks accumulate diarrhetic shellfish toxins (DSTs) from toxigenic microalgae, thus posing a threat to human health by acting as a vector of toxins to consumers. In bivalves, free forms of DSTs can be esterified with fatty acids at the C-7 site to form acyl esters (DTX3), presumably a detoxification mechanism for bivalves. However, the effects of esterification of DSTs on fatty acid metabolism in mollusks remain poorly understood. In this study, mussels (Mytilus galloprovincialis) were fed the DST-producing dinoflagellate Prorocentrum lima for 10 days followed by an additional 10-days depuration in filtered seawater to track the variation in quantity and composition of DST acyl esters and fatty acids. A variety of esters of okadaic acid (OA) and dinophysistoxin-1 (DTX1) were mainly formed in the digestive gland (DG), although trace amounts of esters also appeared in muscle tissue. A large relative amount of OA (60%-84%) and DTX1 (80%-92%) was esterified to DTX3 in the visceral mass (referred to as digestive gland, DG), and the major ester acyl chains were C16:0, C16:1, C18:0, C18:1, C20:1 and C20:2. The DG and muscle tissues showed pronounced differences in fatty acid content and composition during both feeding and depuration periods. In the DG, fatty acid content gradually decreased in parallel with increasing accumulation and esterification of DSTs. The decline in fatty acids was accelerated during depuration without food. This reduction in the content of important polyunsaturated fatty acids, especially docosahexaenoic acid (DHA) and eicosapentaenoic acid (EPA), would lead to a reduction in the nutritional value of mussels. Enzymes involved in lipid metabolism, including acetyl-coenzyme A carboxylase (ACC), fatty acid synthase (FAS), lipoprotein lipase (LPL) and hepatic lipase (HL), were actively involved in the metabolism of fatty acids in the DG, whereas their activities were weak in muscle tissue during the feeding period. This study helps to improve the understanding of interactions between the esterification of DSTs and fatty acid dynamics in bivalve mollusks.

Balanced chemical reaction does not necessarily reveal either the individual elementary reactions by which a reaction occurs or its rate law. In my other articles, you can also check out more blogs about 120-61-6. HPLC of Formula: C10H10O4.