Category: 119993-56-5

On November 24, 1988, Sugiyama, Hidetoshi; Mori, Kogoro; Maeno, Shinichiro; Muramatsu, Norimichi published a patent.Synthetic Route of 119993-56-5 The title of the patent was Aminocyclopentanecarboxylic acid derivatives and agrochemical microbicides containing them. And the patent contained the following:

Agrochem. microbicides contain title compounds I (R = alkyl, alkenyl, alkynyl) or their salts as active ingredients. Treatment of MeOH with SOCl2 at -10° for 10 min, then with cis-I (R = H) HCl salt at room temperature for 30 min gave 88.2% cis-I (R = Me) HCl salt (II), which at 300 ppm totally controlled Phytophthora infestans with no damage to tomato, vs. poor effect, for cycloleucine. A wettable powder was prepared from II (R = H) HCl salt 25, Na lauryl sulfate 2, Na ligninsulfonate 3, white carbon 20, diatomaceous earth 20, and clay 30 parts. The experimental process involved the reaction of Ethyl 2-aminocyclopentanecarboxylate hydrochloride(cas: 119993-56-5).Synthetic Route of 119993-56-5

The Article related to aminocyclopentanecarboxylic acid derivative microbicide agrochem, cyclopentanecarboxylic acid derivative microbicide agrochem, Agrochemical Bioregulators: Microbial and other aspects.Synthetic Route of 119993-56-5

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

On March 2, 2017, Hemeon, Ivan William; Safina, Brian; Sutherlin, Daniel published a patent.Category: esters-buliding-blocks The title of the patent was Preparation of fluorinated aromatic ethers as sodium channel blockers useful in treatment of diseases. And the patent contained the following:

The invention relates to preparation of fluorinated aromatic ethers of formula I wherein the variables RAA, n, ring A, X1, L, m, X2, R2, R3, R4, R5, X, and R6 are as defined in the disclosure, and pharmaceutically acceptable salts thereof, , and compositions containing such compounds that are sodium channel blockers, and methods for using such compounds and compositions for the treatment of various diseases. The experimental process involved the reaction of Ethyl 2-aminocyclopentanecarboxylate hydrochloride(cas: 119993-56-5).Category: esters-buliding-blocks

The Article related to adamantylmethyl fluoroaryl ether preparation sodium channel blocker therapeutic agent, Benzene, Its Derivatives, and Condensed Benzenoid Compounds: Ethers, Sulfides, and The Corresponding Onium Compounds and other aspects.Category: esters-buliding-blocks

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

On December 12, 2008, Dragovich, Peter S.; Murphy, Douglas E.; Dao, Kimkim; Kim, Sun Hee; Li, Lian-Sheng; Ruebsam, Frank; Sun, Zhongxiang; Tran, Chinh V.; Xiang, Alan X.; Zhou, Yuefen published an article.Application of 119993-56-5 The title of the article was Efficient synthesis of (1R,2S) and (1S,2R)-2-aminocyclopentanecarboxylic acid ethyl ester derivatives in enantiomerically pure form. And the article contained the following:

A 4-step synthesis of an optically active synthetic intermediate [(1R,2S)-2-(4′-fluorobenzylamino)cyclopentanecarboxylic acid Et ester complex with (S)-(+)-mandelic acid (I), >99% de] required for the preparation of a promising HCV NS5B polymerase inhibitor is reported. This process utilizes mandelic acid as a resolving agent, which can be recovered in good yield by a simple extraction An optimized version of the chem. described avoids the use of chromatog. purifications making it suitable for large-scale applications. In addition, the straightforward conversion of compound I to enantiomerically pure (1R,2S)-2-aminocyclopentanecarboxylic acid Et ester and the corresponding Boc and Cbz derivatives (Boc = tert-butoxycarbonyl, Cbz = benzyloxycarbonyl) is reported. The preparation of the enantiomer of I, compound (II), in enantiomerically pure form and the conversion of this entity to (1S,2R)-2-aminocyclopentanecarboxylic acid Et ester and the corresponding Boc and Cbz derivatives is also described. The experimental process involved the reaction of Ethyl 2-aminocyclopentanecarboxylate hydrochloride(cas: 119993-56-5).Application of 119993-56-5

The Article related to enantiopure amino cyclopentanecarboxylic acid ethyl complex mandelic acid synthesis, aminocyclopentanecarboxylic acid ethyl ester hcv ns5b polymerase inhibitor preparation, mandelic acid resolving agent extraction hydrogenation and other aspects.Application of 119993-56-5

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics