Category: 112-63-0

Manjunathan, Pandian; Shanbhag, Dhanush Y.; Vinu, Ajayan; Shanbhag, Ganapati V. published the artcile< Recognizing soft templates as stimulators in multivariate modulation of tin phosphate and its application in catalysis for alkyl levulinate synthesis>, Electric Literature of 112-63-0, the main research area is tin phosphate catalysis alkyl levulinate.

Catalyst synthesis is an art where an inefficient material can be remarkably converted into a highly active and selective catalyst by adopting a suitable synthetic strategy to tune its properties during synthesis. The underlying principle of the strategy presented here is the integration of tailoring the structural and chem. behavior of tin phosphates with tuned catalytic active centers directed by employing different structure directing agents (SDAs) and the attempt to understand this in detail. It is demonstrated how soft templates can be effectively used for their so far unknown utilization of tuning the active sites in phosphate containing catalysts. We found that, by using an appropriate synthesis strategy, it is possible to tune and control explicitly both the catalyst morphol. and the nature of active sites at the same time. The 31P MAS NMR study revealed that employing SDAs in the synthesis strongly influenced the nature and amount of phosphate species in addition to porosity. The resultant different nanostructured SnPO catalysts were investigated for one-pot synthesis of alkyl levulinates via alcoholysis of furfuryl alc. Among the catalysts, SnPO-P123 exhibited greater Bu levulinate yield via alcoholysis of furfuryl alc. with n-butanol and the study was extended to synthesize different alkyl levulinates. Importantly, the active sites in the SnPO-P123 catalyst responsible for the reaction were elucidated by a study using 2,6-lutidine as a basic probe mol. This study therefore provides an avenue for rational design and construction of highly efficient and robust nanostructured SnPO catalysts to produce alkyl levulinates selectively.

Catalysis Science & Technology published new progress about Alcoholysis. 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, Electric Literature of 112-63-0.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Navarre, Laure; Martinez, Remi; Genet, Jean-Pierre; Darses, Sylvain published the artcile< Access to enantioenriched α-amino esters via rhodium-catalyzed 1,4-addition/enantioselective protonation>, HPLC of Formula: 112-63-0, the main research area is amino acid ester asym preparation; aryltrifluoroborate amino acrylate conjugate addition protonation rhodium.

Conjugate addition of potassium trifluoro(organo)borates to dehydroalanine derivatives, mediated by a chiral rhodium catalyst and in situ enantioselective protonation, afforded straightforward access to a variety of protected α-amino esters with high yields and enantiomeric excesses up to 95%. Among the tested chiral ligands and proton sources, Binap, in combination with guaiacol (2-methoxyphenol), an inexpensive and nontoxic phenol, afforded the highest asym. inductions. Organostannanes have also shown to participate in this reaction. By a fine-tuning of the ester moiety, and using Difluorophos as chiral ligand, increased levels of enantioselectivity, generally close to 95%, were achieved. Deuterium labeling experiments revealed, and DFT calculation supported, an unusual mechanism involving a hydride transfer from the amido substituent to the α carbon explaining the high levels of enantioselectivity attained in controlling this α chiral center.

Journal of the American Chemical Society published new progress about Amino acid esters Role: SPN (Synthetic Preparation), PREP (Preparation). 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, HPLC of Formula: 112-63-0.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Cai, Xing Hong; Yang, Qiang; Hui, Qun; Wang, Min published the artcile< First-principles calculations of molecular adsorption on the surface of two-dimensional BCOH>, HPLC of Formula: 112-63-0, the main research area is benzenetriboronic acid mol adsorption electronic property.

A two-dimensional structure by the dehydration reaction of 1,3,5-benzenetriboronic acid (shorted as BCOH) is investigated. BCOH is dynamically and thermally stable. It is an indirect semiconductor possessing a band gap of 3.83 eV. The adsorption behavior of CO, CO2, H2, H2O, NH3, NO and NO2 on BCOH are mainly investigated. The results show that most of the gas mols. prefer to adsorb at the interval sites (I1 or I3). The adsorption energies of NO and NO2 are lower than the other mols., revealing that NO and NO2 have better adsorption affinity on BCOH. Except NO and NO2, the band gaps are slightly changed with the mol. adsorption. When NO or NO2 is adsorbed on BCOH, the band gap becomes zero, revealing that a semiconductor-to-metal transition occurs and the conductivity is improved a lot. Thus, BCOH may provide promising potentials for the detection of nitrogen oxides (NO or NO2).

Chemical Physics published new progress about Adsorption. 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, HPLC of Formula: 112-63-0.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Figueroa-Diaz, Andrea Belen; Carlos-Hernandez, Salvador; Diaz-Jimenez, Lourdes published the artcile< Crude glycerol/guishe based catalysts for biodiesel production: conforming a guishe biorefinery>, Reference of 112-63-0, the main research area is glycerol guishe catalyst biodiesel production.

Biodiesel production imposes some challenges, such as the crude glycerol management and cleaning requirements of biodiesel produced by homogeneous transesterification. Heterogeneous catalysts based on residual biomass have been proposed to tackle these challenges; in addition, biomass revalorization is fundamental for biorefineries development. In this research, two organic wastes (crude glycerol and guise) are used to synthesize carbonaceous catalysts. Four catalysts, with different crude glycerol/guishe proportions, were prepared by pyrolysis at 800 and 900°C, followed by a chem. functionalization with H2SO4. SEM (SEM), Fourier transform IR spectroscopy (FT-IR), and thermal gravimetric anal. (TGA) were used to characterize the catalysts. The performance of the catalysts was evaluated in a soybean oil transesterification reaction. The crude glycerol/guishe based catalysts lead to similar biodiesel yields than the obtained with a conventional homogeneous catalyst (CH3NaO). The catalyst identified as BS-25-8 (a mixture of 25% guishe and 75% crude glycerol, pyrolyzed at 800°C and sulfonated), in a proportion of 1 wt%, achieved the highest fatty acid Me esters (FAME) yield (99%) in the transesterification reaction, even surpassing the performance of the CH3NaO (yield of 93%).

Catalysts published new progress about Biodiesel fuel. 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, Reference of 112-63-0.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Bakeev, K. N.; MacKnight, William J. published the artcile< Fluorescent molecular probe technique for assessing the interaction between sulfonated polystyrene and poly(ethylacrylate-co-4-vinylpyridine) ionomers in tetrahydrofuran>, Application of C19H34O2, the main research area is sulfonated polystyrene interaction copolymer THF; ethyl acrylate vinylpyridine copolymer interaction; ionomer interaction THF fluorescent probe.

The interaction between sulfonated polystyrene (I) and Et acrylate-4-vinylpyridine copolymer (II) ionomers was studied over a wide concentration range in THF using a fluorescent mol. probe (1,3,6,8-pyrenetetrasulfonic acid tetra-Na salt) technique. The acid-base interaction between the sulfonate groups of I and the pyridine groups of II and the miscibility of these ionomers are evident for 4.5 and 7.8 mol% pyridine group content in II, and are not detectable for II with 1.7 mol% pyridine groups. Concentration-dependent excimer fluorescence from I-II mixtures indicates the occurrence of polar interactions as a result of proton transfer from the styrenesulfonic acid groups to the pyridine groups. These interactions are clearly evident at high concentrations and are controlled by the high-mol.-weight II component.

Macromolecules published new progress about Chemical chains. 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, Application of C19H34O2.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

He, Yuan; Lou, Jiang; Wu, Kaikai; Wang, Hongmei; Yu, Zhengkun published the artcile< Copper-Catalyzed Radical C-C Bond Cleavage and [4+1] Annulation Cascade of Cycloketone Oxime Esters with Enaminothiones>, Application In Synthesis of 112-63-0, the main research area is thiophene cyanoalkyl amino derivative synthesis; ring cleavage annulation cascade cycloketone oxime ester enamino thione; copper catalyzed radical carbon carbon bond cleavage annulation cascade.

Carbon-carbon bond formation is among the most important reactions in organic synthesis. Reconstruction of a carbon-carbon bond through ring-opening C-C bond cleavage of a strained carbocycle usually occurs via a thermodynamically preferable pathway. However, carbon-carbon bond formation through thermodynamically less favorable C-C bond cleavage has seldom been documented. Herein, we disclose an unusual C-C bond cleavage of cycloketone oxime esters for [4+1] annulation. Under anaerobic copper(I) catalysis, cycloketone oxime esters underwent regioselective, thermodynamically less favorable radical C-C bond cleavage followed by annulation with enaminothiones; i.e., α-thioxo ketene N,S-acetals efficiently affording 2-cyanoalkyl-aminothiophene derivatives Cyclobutanone, -pentanone, -hexanone, and -heptanone oxime esters could act as the effective C1 building blocks in the annulation reaction. An iminyl radical mechanism is proposed for the rare C-C bond cleavage/[4+1] annulation cascade.

Journal of Organic Chemistry published new progress about [4+1] Cycloaddition reaction. 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, Application In Synthesis of 112-63-0.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Young, Nicholas; Hobbs, Mark; Rahnama, Fahimeh; Shi, Jinyang; Briggs, Simon published the artcile< An observational study of high- and low-abundance anti-retroviral resistance mutations among treatment-naive people living with HIV in New Zealand between 2012 and 2017>, Category: esters-buliding-blocks, the main research area is DRM HIV infection; Australasia; HIV infection; anti-HIV agent; anti-retroviral agent; high-throughput nucleotide sequencing; integrase inhibitor.

HIV resistance genotyping detects drug resistance mutations (DRMs) in ≥20% of circulating virus within an infected individual (high-abundance DRMs). Deep sequencing also detects DRMs in smaller viral subpopulations (low-abundance DRMs), although these are of uncertain importance. In this retrospective anal. of 292 treatment-naive patients, high-abundance DRMs were present in 30/292 (10%) patients, but only one (0.3%) had resistance to first-line anti-retrovirals. Low-abundance DRMs were present in 36/247 (15%) patients, but none who received anti-retrovirals for which these were present had virol. failure. These findings demonstrate that starting first-line therapy in treatment-naive patients need not be delayed while awaiting resistance testing.

Internal Medicine Journal published new progress about Antiviral agents. 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, Category: esters-buliding-blocks.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Butin, Noemie; Berges, Cecilia; Portais, Jean-Charles; Bellvert, Floriant published the artcile< An optimization method for untargeted MS-based isotopic tracing investigations of metabolism>, Category: esters-buliding-blocks, the main research area is isotopic iquid chromatog mass spectrometry metabolism computer software; Isotope labelling experiments; LC/MS; Parameter optimization; Untargeted analysis.

Stable isotope tracer studies are increasingly applied to explore metabolism from the detailed anal. of tracer incorporation into metabolites. Untargeted LC/MS approaches have recently emerged and provide potent methods for expanding the dimension and complexity of the metabolic networks that can be investigated. A number of software tools have been developed to process the highly complex MS data collected in such studies; however, a method to optimize the extraction of valuable isotopic data is lacking. To develop and validate a method to optimize automated data processing for untargeted MS-based isotopic tracing investigations of metabolism The method is based on the application of a suitable reference material to rationally perform parameter optimization throughout the complete data processing workflow. It was applied in the context of 13C-labeling experiments and with two different software, namely geoRge and X13CMS. It was illustrated with the study of a E. coli mutant impaired for central metabolism The optimization methodol. provided significant gain in the number and quality of extracted isotopic data, independently of the software considered. Pascal triangle samples are well suited for such purpose since they allow both the identification of anal. issues and optimization of data processing at the same time. The proposed method maximizes the biol. value of untargeted MS-based isotopic tracing investigations by revealing the full metabolic information that is encoded in the labeling patterns of metabolites.

Metabolomics published new progress about Computer program (geoRge, X13CMS). 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, Category: esters-buliding-blocks.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Boyles, David C.; Curran, Timothy T.; Greene, Derek; Macikenas, Dainius; Parlett, Roger V. published the artcile< Novel, base-promoted reaction of N-alkoxycarbonyl-O-(halo-substituted 4-nitrophenyl)hydroxylamines>, Synthetic Route of 112-63-0, the main research area is alkoxycarbonyl hydroxyaniline preparation; nitrophenyl alkoxycarbonyl hydroxylamine base reaction.

The base-promoted reactions of N-alkoxycarbonyl-O-(nitrophenyl)hydroxylamines which contain a halogen attached to the aromatic ring were described. The reaction is promoted under mild conditions (NaHCO3 or K2CO3) and provides N-alkoxycarbonyl-N-hydroxyaniline. In a crossover experiment, some scrambling was observed which suggests that the reaction is inter- and intramol. in nature. N-Boc-(2,6-dichloro-4-nitrophenyl)hydroxylamine was also found to N-Boc aminate Bn2NH to form the protected hydrazine in modest yield. For example, treatment of (2,6-dichloro-4-nitrophenoxy)carbamic acid 1,1-dimethylethyl ester with sodium hydrogen carbonate gave an N-hydroxyaniline derivative, i.e., (2,6-dichloro-4-nitrophenyl)hydroxycarbamic acid 1,1-dimethylethyl ester (I). Further reaction of I with N-(phenylmethyl)benzenemethanamine gave 2,2-bis(phenylmethyl)hydrazinecarboxylic acid 1,1-dimethylethyl ester.

Tetrahedron Letters published new progress about 112-63-0. 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, Synthetic Route of 112-63-0.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Ucar, Mualla Balaban; Ucar, Gunes published the artcile< Characterization of methanol extracts from Quercus hartwissiana wood and bark>, Formula: C19H34O2, the main research area is Quercus wood bark.

The MeOH extracts of wood and bark from Quercus hartwissiana have been investigated by GC-MS after derivatization, as well as by classical spectroscopic methods. The results for the free compounds revealed that ellagic acid, catechin, gallic acid, quercitol, and also long chain fatty acids, sugars, and sitosterol were the essential compounds in wood and bark, most of them being present in differing amounts The results for the free compounds revealed that ellagic acid, catechin, gallic acid, quercitol, and also long chain fatty acids, sugars, and sitosterol were the essential compounds in wood and bark, most of them being present in differing amounts Amounting to 1/4th to 1/3rd of the free compounds, the bark had the highest catechin content. While the content of sugars, such as fructose and glucose, increased in sapwood and bark extracts remarkably, the amounts of these compounds decreased in extracts of heartwood. The profile of the bound compounds contained sugars (i.e., arabinose, xylose, and, above all, glucose), ellagic and gallic acids, quercitols, and inositols. Compared with the composition of free compounds, the hydrolyzed extracts showed relatively higher amounts of sugars, especially glucose, gallic acid and quercitol.

Chemistry of Natural Compounds published new progress about Bark. 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, Formula: C19H34O2.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics