Category: 112-63-0

Khalaj, A.; Rastegi, H. R.; Jorjani, M. published the artcile< Synthesis and muscle relaxant activity of two analogs of dantrolene sodium in mice>, Quality Control of 112-63-0, the main research area is dantrolene sodium analog preparation muscle relaxant structure.

Dantrolene sodium (I) is a skeletal muscle relaxant that is known to act by preventing the release of calcium ions from the sarcoplasmic reticulum. Structure-activity studies of I have been limited to changes in the position or the nature of the nitro group, and replacement of the 4-nitrobenzene, furan, and hydantoin moieties with other rings, usually resulting in compounds with reduced or no activity. To investigate the influence of similarities in the electronic transmission ability of the furan nucleus of 5-aryl, 5-arylthio and 5-styryl-2-furancarboxaldehydes on biol. activity, two corresponding analogs of I were prepared by the reaction of the resp. aldehydes with 1-aminohydantoin and were evaluated by the rota-rod test in mice. Compared with I as standard, 1-[[[[5-(4-nitrobenzene)thio]-2-furanyl]-methylene]amino]-2,4-imidazolidinedione exhibited higher activity, and 1-[[[[5-(4-nitrobenzene)ethenyl]-2-furanyl]-methylene]amino]-2,4-imidazolidinedione showed comparable activity at 0·5, 3 and 6 h after administration to mice. There is a correlation between the electronic transmission ability of the furan nucleus in all 3 compounds and muscle relaxant activity.

Pharmacy and Pharmacology Communications published new progress about Muscle relaxants. 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, Quality Control of 112-63-0.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Miao, Pengcheng; Leng, Xuefei; Liu, Jie; Song, Guanjun; He, Maomao; Li, Yang published the artcile< Regulating the Dynamic Behaviors of Transcarbamoylation-Based Vitrimers via Mono-Variation in Density of Exchangeable Hydroxyl>, Related Products of 112-63-0, the main research area is dynamic behavior transcarbamoylation vitrimer.

The dynamic behaviors of vitrimer are influenced by the interaction of crosslink d. and d. of exchangeable groups, which results in the difficulty of extracting the effect of mono-variation. In this study, the dynamic behaviors of vitrimer were tuned by changing the d. of exchangeable hydroxyls alone, while leaving the crosslink d. undisturbed. A multi-hydroxy vitrimer network without a loading catalyst was synthesized successfully. Three-armed functionalized polycarbonate, obtained by ring-opening polymerization of 1,3-dioxan-2-one and its derivatives, was treated as a precursor polymer. Afterward, the precursor polymer was converted into vitrimer in a single step by treatment with hexamethylene diisocyanate. When the system with constant crosslink d. was established, the accurate effect of the hydroxyl d. on the dynamic behaviors could be characterized by stress relaxation. The relationship of essential dynamic behavioral parameters, such as topol. freezing transition temperature (Tv), exchange activation energy (Ea), and Arrhenius prefactor (τ0), with the d. of exchangeable hydroxyls was quant. discussed. The results indicated that Tv and Ea were neg. correlated with the d. of exchangeable hydroxyls, while τ0 showed a pos. correlation. In addition, linear models were developed to describe the relationship between dynamic behaviors of vitrimer and d. of exchangeable hydroxyls. It is expected that the findings can be applied to precisely control Ea, τ0, Tv, and characteristic relaxation time (τ*) of vitrimer and can also be used as a model for the synthesis of various vitrimer materials.

Macromolecules (Washington, DC, United States) published new progress about Activated charcoal Role: CAT (Catalyst Use), USES (Uses). 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, Related Products of 112-63-0.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Klein, Robert S.; Lim, Mu-Ill; Tam, Steve Y. K.; Fox, Jack J. published the artcile< New synthesis of 5H-pyrrolo[3,2-d]pyrimidines via pyrimido[5,4-c]pyridazines>, Recommanded Product: (9Z,12Z)-Methyl octadeca-9,12-dienoate, the main research area is pyrrolopyrimidinedione; pyrimidopyridazine ring contraction; pyrimidine phenylazo formylation cyclization; cyclization formylphenylazopyrimidine.

5H-pyrrolo[3,2-d]pyrimidines I and II (R = Me2N, H2N) were prepared from 6-methyl-5-phenylazopyrimidines by conversion to intermediate pyrimido[[[5,4-c]pyridazines, e.g. III, by treatment with formylating agents such as tert-butoxybis(dimethylamino)methane. Hydrogenolytic ring contractions then give I or II; other methods for this preparation were given.

Journal of Organic Chemistry published new progress about Cyclocondensation reaction. 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, Recommanded Product: (9Z,12Z)-Methyl octadeca-9,12-dienoate.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Sayama, Shinsei; Onami, Tetsuo published the artcile< Esterification of aldehydes and alcohols with pyridinium hydrobromide perbromide in water>, Related Products of 112-63-0, the main research area is aldehyde alc esterification pyridinium hydrobromide perbromide water; ester preparation; pyridinium hydrobromide perbromide esterification mediator; water esterification solvent.

The direct esterification of aldehydes and alcs. was carried out with pyridinium hydrobromide perbromide in water at room temperature A variety of aldehydes were converted to resp. ester derivatives with alcs. such as methanol, 1,2-ethanediol, 1,3-propanediol. Further, a variety of aliphatic alcs. were also converted to the corresponding Tishchenko-like dimeric esters in good yields under the same reaction conditions.

Synlett published new progress about Alcohols Role: RCT (Reactant), RACT (Reactant or Reagent). 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, Related Products of 112-63-0.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Torabi, Mostafa; Yaghoobi, Fatemeh; Karimi Shervedani, Reza; Kefayat, Amirhosein; Ghahremani, Fatemeh; Rashidiyan Harsini, Parisa published the artcile< Mn(II) & Gd(III) deferrioxamine complex contrast agents & temozolomide cancer prodrug immobilized on folic acid targeted graphene/polyacrylic acid nanocarrier: MRI efficiency, drug stability & interactions with cancer cells>, Computed Properties of 112-63-0, the main research area is temozolomide cancer folic acid graphene deferrioxamine complex drug stability.

Nanocomposite systems, consisting of the reduced graphene oxide/polyacrylic acid as nanocarrier, integrated with folic acid targeting agent and further modified by Deferrioxamine-M (M: Mn2+ or Gd3+) as the diagnostic MRI contrast agents or Temozolomide as a therapeutic agent, abbreviated as (i) GNs@PAA-[DFO-Mn(II)]/FOA, (ii) GNs@PAA-[DFO-Gd(III)]/FOA, and (iii) GNs@PAA-FOA/TMZ, were synthesized, characterized, and examined for B16F10 Melanoma cells through in-vitro/in-vivo methods. Physicochem. characterization of the prepared systems was performed by using DLS, ζ-potential, TEM, FTIR, UV-vis, XPS, fluorescence, and electrochem. methods. The biocompatibility of the nanocarrier was implicated according to the histopathol. evaluation of the H&E stained sections of vital organs. Release studies at biol. pH 7.4, revealed good stability for TMZ immobilized on the GNs@PAA-FOA/TMZ nanocarrier. The in-vitro MRI studies of the GNs@PAA-[DFO-Mn(II)]/FOA and GNs@PAA-[DFO-Gd(III)]/FOA systems revealed longitudinal relaxivities of 13.00 and 20.64 mM-1 s-1, using variations of the spin-lattice relaxation rates (r1 = 1/T1) as a function of the systems concentrations, resp. These systems were studied further by the in-vivo method. The obtained images supported their ability for MRI imaging. The intracellular delivery of the system was monitored and supported by flow cytometry based on PI florescent dye loaded onto the introduced nanocarrier, GNs@PAA-FOA/PI. The interaction of the GCE-GNs@PAA-FOA/TMZ, GCE-GNs@PAA-[DFO-Mn(II)]/FOA, and GCE-GNs@PAA-[DFO-Gd(III)]/FOA systems with cancer cells was investigated through electrochem. impedance spectroscopy. The results showed a high affinity of the systems toward B16F10 Melanoma cells with the selectivity degrees of 12.96, 9.92, and 9.62, resp., compared with L929 cells.

Colloids and Surfaces, A: Physicochemical and Engineering Aspects published new progress about Antitumor agents. 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, Computed Properties of 112-63-0.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Santosh, Mada SSNM; Sadavarte, Vaibhav S.; Kumar, Amit; Pande, Shrikant M.; Kulkarni, Prashant S. published the artcile< Examining the Effect of Trimethylol Propane Crosslinker on Butanetriol Trinitrate Plasticized Polycaprolactone Polymer Networks of Propellant Binder System>, Computed Properties of 112-63-0, the main research area is trimethylol propane crosslinker butanetriol trinitrate plasticize polycaprolactone; polymer propellant binder system.

The knowledge of polymer network characteristics is important to tune the properties of advanced energetic propellants based on nitrate ester plasticized polyol binder system. In this article, plasticized polyurethane networks of polycaprolactone (PCP) and hydroxyl-terminated polybutadiene (HTPB) with different crosslinker content [0 to 0.20 parts] at various stoichiometric NCOOH ratios (r-value) [0.8 to 1.0] were studied. Five numbers of polyurethane networks of 1,2,4-butanediol trinitrate (BTTN) plasticised PCP were formulated at each r value 0.8, 0.9 and 1.0 using 0, 0.05, 0.10, 0.15 and 0.20 parts of trimethylolpropane (TMP) crosslinker. Similarly, five numbers of dioctyl adipate (DOA) plasticized HTPB based polyurethane networks were formulated at r-value of 0.8. FT-IR spectra of these polyurethane networks (PUNs) were recorded for functional group identification. Stress-strain behavior of PUNs was studied for understanding the effect of TMP content and r value on mech. properties. Hard segment content of PUNs were calculated and its influence on network characteristics and mech. properties was evaluated. CLD values (ν) increased with increase of hard segment content of PUN and the values quantified by different approaches followed the trend νe (by solvent swelling method) > νne2(by Initial modulus method)>νne1 (by Mooney Rivlin method).

Propellants, Explosives, Pyrotechnics published new progress about Binders. 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, Computed Properties of 112-63-0.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Heda, Jidnyasa; Niphadkar, Prashant; Mudliar, Sandeep; Bokade, Vijay published the artcile< Highly efficient micro-meso acidic H-USY catalyst for one step conversion of wheat straw to ethyl levulinate (biofuel additive)>, Category: esters-buliding-blocks, the main research area is ethyl levulinate wheat straw homogeneous catalyst physicochem property.

Et Levulinate (EL), biofuel additive can blend up to 20% with biodiesel to improve its fuel properties. Till the date, there are reports on homogeneous catalysts (H2SO4, ionic liquid) for synthesis of EL from raw biomass like wheat straw. To best of our knowledge, there is no single report on heterogeneous catalyst for one step synthesis of EL directly from wheat straw. This work is a successful attempt to use heterogeneous micro-meso acidic H-USY (post dealumination and desilication) for direct one step conversion of wheat straw to EL with higher EL yield 24.5 weight%, which is probably the highest so far.

Microporous and Mesoporous Materials published new progress about Adsorption. 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, Category: esters-buliding-blocks.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Turchaninov, V. K.; Motvienko, E. A.; Larina, L. I.; Shulunova, A. M.; Baikalova, L. V.; Lopyrev, V. A. published the artcile< Study of benzimidazoles. 8. Relationship between the UV and photoelectron spectra>, Reference of 112-63-0, the main research area is benzimidazole UV spectra photoelectron spectra; MO benzimidazole derivative energy level.

The nature of the first two long-wavelength bands in the UV spectra of 2-substituted benzimidazoles has been analyzed on the basis of photoelectron spectra. Three basic types of spectroscopic situations are typical of these compounds: (1) a change in the sequence of occupied MO of the ground state does not influence the order of excited energy levels; (2) if the π levels follow in the same order, an inversion of excited states occurs; (3) a reversal of occupied π MO of the ground state causes an inversion of excited states.

Izvestiya Akademii Nauk, Seriya Khimicheskaya published new progress about Electronic state. 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, Reference of 112-63-0.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Oprescu, Elena-Emilia; Enascuta, Cristina-Emanuela; Radu, Elena; Lavric, Vasile published the artcile< Synthesis and evaluation of levulinic ester as biodiesel additives>, Formula: C19H34O2, the main research area is TiO2 La2O3 levulinic ester biodiesel additive.

In this study, the SO42-/TiO2-La2O3-Fe2O3 catalyst was prepared and tested in the conversion of fructose to Et levulinate. The catalyst was characterized from the point of view of the textural anal., FT-IR anal., acid strength distribution, X-ray powder diffraction and pyridine adsorption IR spectra. The influence of the reaction parameters on the Et levulinate yield was study. The maximum yield of 37.95% in levulinate esters was obtained at 180°C, 2 g catalyst and 4 h reaction time. The effect of Et levulinate addition to diesel-biodiesel blend in different rates, i.e, 0.5, 1, 2.5, 5 (w.t %) on d., kinematic viscosity and flash point was evaluated and compared with the European specification.

Revista de Chimie (Bucharest, Romania) published new progress about Biodiesel fuel. 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, Formula: C19H34O2.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Vasyliev, G.; Vorobyova, V.; Zhuk, T.; Kalinchuk, O. published the artcile< Agricultural by-product extracts as scale inhibitors of mild steel in tap water>, Computed Properties of 112-63-0, the main research area is agricultural byproduct extract scale inhibitor mild steel tap water.

Three industry byproducts, namely rapeseed pomace from the wastes of edible oil production, sugar beet pulp from the wastes of sugar production and fodder radish cake, have been tested as scale inhibitors of mild steel in tap water. Ethanol extracts were prepared by maceration and the electrochem. approach to study the scale formation was utilized, based on the measurement of oxygen reduction current during nucleation and formation of calcium carbonate in the presence of extracts Scaling time, porosity and area d. of the scale was determined and used to characterize the inhibition efficiency. Chem. compositions of extracts were analyzed by GC-MS anal. (gas chromatog. with mass selective detector by mass selective integration). The rapeseed pomace extract and fodder radish cake extract at the concentration of 10 mL/L appeared to be efficient scaling inhibitors. Sugar beet pulp extract increases the crystallization time, however the amount of deposited scale appeared to be the same as in the tap water. The scale inhibition is caused mainly by the formation of adsorbed film on the scale nucleus that blocks the surface and prevent further crystal growth.

Materials Today: Proceedings published new progress about Adsorption. 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, Computed Properties of 112-63-0.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics