Category: 112-63-0

Zhang, Zhenhua; Gorski, Bartosz; Leonori, Daniele published the artcile< Merging Halogen-Atom Transfer (XAT) and Copper Catalysis for the Modular Suzuki-Miyaura-Type Cross-Coupling of Alkyl Iodides and Organoborons>, Quality Control of 112-63-0, the main research area is alkyl iodide aryl organoboron copper catalyst Suzuki Miyaura coupling; aryl alkane preparation.

A mechanistically distinct approach to achieve Suzuki-Miyaura-type cross-couplings between alkyl iodides and aryl organoborons was reported. This process required a copper catalyst but, in contrast with previous approaches based on palladium and nickel systems, does not utilizes the metal for the activation of the alkyl electrophile. Instead, this strategy exploited the halogen-atom transfer ability of α-aminoalkyl radicals to convert secondary alkyl iodides into the corresponding alkyl radicals that then were coupled with aryl, vinyl, alkynyl, benzyl and allyl boronate species. These novel coupling reactions feature simple set up and conditions (1 h at room temperature) and facilitate access to privileged motifs targeted by the pharmaceutical sector.

Journal of the American Chemical Society published new progress about Alcohols Role: RCT (Reactant), RACT (Reactant or Reagent). 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, Quality Control of 112-63-0.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Garcia-Garcia, Amalia; Oyarzabal, Itziar; Cepeda, Javier; Seco, Jose M.; Garcia-Valdivia, Antonio A.; Gomez-Ruiz, Santiago; Salinas-Castillo, Alfonso; Choquesillo-Lazarte, Duane; Rodriguez-Dieguez, Antonio published the artcile< Slow relaxation of magnetization and luminescence properties of a novel dysprosium and pyrene-1,3,6,8-tetrasulfonate based MOF {[Dy4(μ-pytet)(μ4-pytet)2(DMF)20(H2O)2]·4DMF·4H2O}n (1).>, Synthetic Route of 112-63-0, the main research area is dysprosium pyrenetetrasulfonate MOF preparation crystal structure magnetic relaxation luminescence.

The authors report the formation of a novel multifunctional metal-organic framework (MOF) based on Dy(III) ions using pyrene-1,3,6,8-tetrasulfonate (pytet)4- as a ligand, synthesized using a soft hydrothermal route. This material shows a two-dimensional network with small channels along a crystallog. axis and displays intense photoluminescence properties in the solid state at room temperature due to the pyrene derivative ligand. The magnetic properties of this 2-dimensional-MOF are also accomplished, confirming slightly frequency-dependent out of phase signals under an applied field of 1000 Oe.

New Journal of Chemistry published new progress about Color. 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, Synthetic Route of 112-63-0.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Lemieux, Robert P.; Schuster, Gary B. published the artcile< Photochemistry of axially chiral (arylmethylene)cycloalkanes: a search for suitable photoswitchable liquid crystalline materials>, Quality Control of 112-63-0, the main research area is arylmethylenecycloalkane photochem liquid crystal optical switch; optical absorption CD arylmethylenecycloalkane; photoracemization axially chiral arylmethylenecycloalkane.

A series of chiral (arylmethylene)cycloalkanes was synthesized in racemic and optically active form to examine their suitability for incorporation in a liquid crystal-based optical switch. Irradiation of these compounds with UV light leads to their rapid photoracemization and, in some cases, their simultaneous destruction. The absorption spectra and CD spectra of these optically active compounds were determined Chiral exciton coupling theory proves to be a good guide for predicting the magnitude of Δε and gλ (the Kuhn anisotropy factor). Addition of the optically active (arylmethylene)cycloalkanes to nematic liquid crystal materials induces cholesteric behavior. The helical twisting power (βM) was determined for each compound, and a limit of 90 μm was established for the detection of a long-pitch cholesteric liquid crystal. Irradiation of the cholesteric liquid crystals formed by addition of the optically active (arylmethylene)cycloalkanes induces the transition to a compensated nematic phase that is readily sensed by optical microscopy.

Journal of Organic Chemistry published new progress about Circular dichroism. 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, Quality Control of 112-63-0.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Wang, Lei; Ni, Qijian; Bluemel, Marcus; Shu, Tao; Raabe, Gerhard; Enders, Dieter published the artcile< NHC-Catalyzed Asymmetric Synthesis of Functionalized Succinimides from Enals and α-Ketoamides>, Synthetic Route of 112-63-0, the main research area is succinimide preparation enantioselective diastereoselective; ketoamide aldehyde cycloaddition heterocyclic carbene catalyst; N-heterocyclic carbenes; asymmetric synthesis; ketoamides; organocatalysis; succinimides.

The efficient asym. synthesis of highly substituted succinimides (3R/3S,4R) I (R = 2-ClC6H4, 4-H3COC6H4, 3-thienyl, etc.; R1 = CH3, 4-H3CC6H4, 2-furyl; R2 = C6H5, 3-ClC6H4, 4-H3COC6H4, 2-(methoxycarbonyl)-3-thienyl) from α,β-unsaturated aldehydes and α-ketoamides via N-heterocyclic carbene (NHC) catalyzed [3+2] cycloaddition has been developed. The new scalable protocol significantly expands the utility of NHC catalysis for the synthesis of heterocycles II (X = C6H5, 4-H3COC6H4; Y = C6H5, 2-furyl; Z = C6H5, 2-(methoxycarbonyl)-3-thienyl) and provides easy access to assemble a wide range of succinimides I from simple starting materials.

Chemistry – A European Journal published new progress about [3+2] Cycloaddition reaction, stereoselective ((3+2)). 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, Synthetic Route of 112-63-0.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Detert, Heiner; Sugiono, Erli published the artcile< Synthesis and electronic spectra of substituted oligo(phenylenevinylene)s>, Recommanded Product: (9Z,12Z)-Methyl octadeca-9,12-dienoate, the main research area is oligophenylenevinylene preparation UV fluorescence.

A series of substituted oligo(p-phenylenevinylene)s (OPVs) with five benzene rings was prepared via PO-activated olefinations and Knoevenagel condensations. The central ring is substituted with two octyloxy groups to ensure good solubility of the OPVs and the lateral styrene units carry further substituents, with either electron-accepting or donating character and also combinations thereof. The spectral features of these OPVs are dominated by the basic chromophore; further auxochrome groups on the lateral rings (meta and para positions) shift the absorption and emission spectra only slightly to longer wavelengths. Significant bathochromic shifts (absorption ca 20 nm, emission ca 40 nm) are observed for OPVs with cyano groups on the terminal vinylene segments. The absorption spectra are independent of the concentration and solvatochromism is very small. The OPVs are photochem. stable to near-UV irradiation (366 nm) in neutral solution, whereas mid-UV irradiation (254 nm) causes decomposition of the chromophore. The presence of traces of acids or amines leads to different photochem. pathways.

Journal of Physical Organic Chemistry published new progress about Fluorescence. 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, Recommanded Product: (9Z,12Z)-Methyl octadeca-9,12-dienoate.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Srinivasulu, Vunnam; Janda, Kim D.; Abu-Yousef, Imad A.; O’Connor, Matthew John; Al-Tel, Taleb H. published the artcile< A modular CuI-L-proline catalyzed one-pot route for the rapid access of constrained and privileged hetero-atom-linked medium-sized ring systems>, Formula: C19H34O2, the main research area is benzodiazepinone benzodiazocinone benzooxazocinone benzothiazapine benzothiazine indole preparation.

An efficient CuI-L-proline catalyzed one-pot synthesis was developed to generate a collection of skeletally diverse heterocyclic ring systems with sizes ranging from 6 to 9. A salient feature of this design strategy was its modular synthetic utility using an SN2 reaction followed by a microwave assisted CuI-L-proline hetero-arylation, which has granted access to a series of heterocyclic frameworks, including: benzo[e]pyrrolo[1,2-a][1,4]diazepin e.g. I, benzo[e]pyrrolo[1,2-a][1,4]diazocin, benzo[e]pyrido[1,2-a][1,4]diazocinones, dibenzo[b,f][1,5]diazoninones, dihydrodibenzo[b,e][1,4]thiazepine, dibenzo[b,e][1,4]thiazocine and benzo[6,7][1,4]diazepino[1,2-a]indole. Moreover, the synthetic procedures described allows rapid entries to synthetically challenging medium-sized heterocyclic systems with good overall yields.

Tetrahedron published new progress about Amides Role: RCT (Reactant), RACT (Reactant or Reagent). 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, Formula: C19H34O2.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Takaya, Jun; Ito, Shisei; Nomoto, Hironori; Saito, Narumasa; Kirai, Naohiro; Iwasawa, Nobuharu published the artcile< Fluorine-controlled C-H borylation of arenes catalyzed by a PSiN-pincer platinum complex>, Application In Synthesis of 112-63-0, the main research area is fluorine controlled carbon hydrogen borylation arene catalyst; phosphorus silicon nitrogen pincer platinum complex catalyzed regioselective borylation; arylboronic ester regioselective synthesis; crystal mol structure phosphorus silicon nitrogen pincer platinum complex.

An efficient, regioselective synthesis of fluorine-substituted arylboronic esters was achieved through fluorine-controlled C-H borylation of arenes with diboron catalyzed by a PSiN-platinum complex. The promising utility of the PSiN-platinum catalyst and its unique regioselectivity were demonstrated for the first time, which would complement the well-developed Ir-catalyzed C-H borylation.

Chemical Communications (Cambridge, United Kingdom) published new progress about Aromatic hydrocarbons Role: RCT (Reactant), RACT (Reactant or Reagent). 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, Application In Synthesis of 112-63-0.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Zhao, Guozhong; Li, Jingjing; Zheng, Fuping; Yao, Yunping published the artcile< The fermentation properties and microbial diversity of soy sauce fermented by germinated soybean>, Related Products of 112-63-0, the main research area is soy sauce fermentation germinated soybean microbial diversity; antioxidant activity; flavor components; gamma-aminobutyric acid; germinated soybean sauce; microbial diversity.

The quality of com. soy sauce is variable at present. Tech. work is needed to improve the quality and flavor of soy sauce, especially in China. Material is a factor for influencing soy sauce characters in fermentation Germinated soybean sauce (fermented by germinated soybean) had a gamma aminobutyric acid (GABA) concentration of 6.83μg mL-1, whereas a control (a soy sauce fermented by soybean) had a GABA concentration of less than 2.42μg mL-1. Germinated soybean sauce also contained significantly higher levels of isoflavones, total polyphenol, and amino acid nitrogen than the control soy sauce. Microbial diversity results showed that Bacillus was the dominant bacteria in germinated soy sauce compared with the control. Aldehydes, alcs., esters, and phenols were the major flavor components of germinated soybean sauce. A soy sauce with high levels of GABA, isoflavones, and total polyphenol was developed using germinated soybean. Stenotrophomonas, the typical pathogen found in the control, was reduced dramatically and replaced by Bacillus during fermentation with the germinated soybean. The germinated soybean sauce exhibited a better aroma and taste than the control. Soy sauce fermented by soybeans that germinated for 48 h exhibited greater advantages than soy sauce that germinated for 24 and 72 h. 2020 Society of Chem. Industry.

Journal of the Science of Food and Agriculture published new progress about Alcohols Role: BSU (Biological Study, Unclassified), BIOL (Biological Study). 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, Related Products of 112-63-0.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Fan, Rong-Hua; Liu, Chen-Guang; Zhang, Ze; Xing, Mei-Qi; Han, Yu-Mo; Zhou, Tao; Wang, Xin-Yue; Wang, Chen published the artcile< Metabolomics analysis of Semen Cuscutae protection of kidney deficient model rats using ultra high-performance liquid chromatography-quadrupole time-of-flight Mass Spectrometry>, Application In Synthesis of 112-63-0, the main research area is metabolomics semen cuscutae liquid chromatog mass spectrometry; Kidney yang deficiency syndrome; Metabolomics; Semen Cuscutae; UPLC-QTOF/MS.

The traditional Chinese medicine syndrome “”Kidney yang deficiency”” is a kind of chronic kidney disease. With the development of society, the incidence of chronic kidney disease is increasing year by year, which also brings great economic pressure to people. Semen Cuscutae is an important traditional Chinese medicine to tonify liver and kidney, mainly used to tonify deficiency of liver and kidney, spleen and kidney deficiency and diarrhea. Although there are a lot of research at the mol. and cellular level to study the Semen Cuscutae on the treatment of Kidney yang deficiency syndrome, but there’s no comprehensive research complete with metabolomics method from plasma, feces and urine metabolites aspects. The purpose of this study is to find the potential differential biomarkers of the Kidney yang deficiency model and blank group rats in plasma, urine and feces, and to investigate the mechanism of Semen Cuscutae in the treatment of Kidney yang deficiency syndrome. In this study, ultra high-performance liquid chromatog.-quadrupole time-of-flight Mass Spectrometry (UPLC-QTOF/MS) was used to identify potential biomarkers. Through the anal. of metabolic profiles of plasma, urine, and feces, as well as multivariate statistical anal. and pathway anal., the therapeutic mechanism of Semen Cuscutae for Kidney yang deficiency syndrome was described. The results showed that there were 69 differential metabolites in plasma, 93 differential metabolites in feces and 62 differential metabolites in urine, and the changes of the levels of these biomarkers showed that Semen Cuscutae had a good therapeutic effect on Kidney yang deficiency syndrome. Through the anal. of the channel, the metabolite changes mainly affected the steroid hormone biosynthesis, arachidonic acid metabolism, primary bile acid biosynthesis, sheath lipid metabolism and biosynthesis of tyrosine, phenylalanine metabolism, retinol metabolism,taurine and hypotaurine metabolism, lysine degradation and vitamin B6 metabolism, tryptophan metabolism, terpenoid backbone biosynthesis and starch and sucrose metabolism Therefore, the results suggested that Semen Cuscutae could exert a good therapeutic effect by reversing the levels of some biomarkers.

Journal of Pharmaceutical and Biomedical Analysis published new progress about Bile acids Role: BSU (Biological Study, Unclassified), BIOL (Biological Study). 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, Application In Synthesis of 112-63-0.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Hu, Shaojian; Zhu, Jianhua; Wu, Bencheng; Ma, Rui; Chang, Yuechun; Li, Xiaohui; Wei, Yuqing; Yu, Liujie published the artcile< Green synthesis of ester base oil with high viscosity - Part I: Catalyst preparation, characterization, evaluation, and mechanism analysis>, Recommanded Product: (9Z,12Z)-Methyl octadeca-9,12-dienoate, the main research area is green ester base oil lubricant viscosity catalyst preparation.

High viscosity ester base oil, as an eco-friendly lubricant base oil with high performance, can significantly reduce the friction, wear, and energy consumption of large machinery. However, there is less research on the preparation of heterogeneous catalysts for synthesis of high viscosity ester oil. In this work, Sn/Zr mixed oxide catalysts were prepared for the green synthesis of ester base oil with high viscosity. This approach gets rid of addnl. template, surfactant, organic solvent, sulfur, nitrogen, phosphorus, and halogen, thereby avoiding the potential environmental pollution. A superior powd. catalyst MO-Sn8Zr-9.0-160-18 was developed with optimized Sn/Zr molar ratio, pH, hydrothermal temperature, and hydrothermal time of 8:1, 9.0, 160°, and 18 h, resp. Results of catalyst characterization indicated that the developed catalysts were mesoporous materials with hydrophobic properties, allowing for free diffusion of macromols., adsorption of reactants, and desorption of water. Addnl., the sp. surface area, pore volume, pore diameter, and surface hydrophobicity of catalyst were enhanced by doping Zr, so the catalysts with higher [Sn/Zr]ICP/[Sn/Zr]XPS exhibited better catalytic activity. Preformed catalyst was prepared by simple mech. mixing method to achieve better catalyst separation The sp. surface area, acid amount, and acid strength of catalyst were indeed improved significantly after catalyst molding. By programmed heating, the preformed catalyst achieved a maximum carboxyl conversion of 97.2%. Moreover, spent catalyst could be reactivated via solvent washing, drying, calcination, and hydrogen reduction, exhibiting good reusability.

Fuel published new progress about Base oils. 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, Recommanded Product: (9Z,12Z)-Methyl octadeca-9,12-dienoate.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics