Chemical profiling of the human skin surface for malaria vector control via a non-invasive sorptive sampler with GCxGC-TOFMS was written by Wooding, Madelien;Rohwer, Egmont R.;Naude, Yvette. And the article was included in Analytical and Bioanalytical Chemistry in 2020.Related Products of 112-14-1 The following contents are mentioned in the article:
Volatile organic compounds (VOCs) and semi-VOCs detected on the human skin surface are of great interest to researchers in the fields of metabolomics, diagnostics, and skin microbiota and in the study of anthropophilic vector mosquitoes. Mosquitoes use chem. cues to find their host, and humans can be ranked for attractiveness to mosquitoes based on their skin chem. profile. Addnl., mosquitoes show a preference to bite certain regions on the human host. The chem. differences in the skin surface profiles of 20 human volunteers were compared based on inter-human attractiveness to mosquitoes, as well as inter- and intra-human mosquito biting site preference. A passive, non-invasive approach was followed to sample the wrist and ankle skin surface region. An inhouse developed polydimethylsiloxane (PDMS) passive sampler was used to concentrate skin VOCs and semi-VOCs prior to thermal desorption directly in the GC inlet with comprehensive gas chromatog. coupled to time-of-flight mass spectrometry (GCxGC-TOFMS). Compounds from a broad range of chem. classes were detected and identified as contributing to the differences in the surface skin chem. profiles. 5-Ethyl-1,2,3,4-tetrahydronaphthalene, 1,1鈥?oxybisoctane, 2-(dodecyloxy)ethanol, 伪,伪-dimethylbenzene methanol, Me salicylate, 2,6,10,14-tetramethylhexadecane, 1,2-benzenedicarboxylic acid, bis(2-methylpropyl) ester, 4-methylbenzaldehyde, 2,6-diisopropylnaphthalene, n-hexadecanoic acid, and 纬-oxobenzenebutanoic acid Et ester were closely associated with individuals who perceived themselves as attractive for mosquitoes. Addnl., biol. lead compounds as potential attractants or repellents in vector control strategies were tentatively identified. Results augment current knowledge on human skin chem. profiles and show the potential of using a non-invasive sampling approach to study anthropophilic mosquito-host interactions. This study involved multiple reactions and reactants, such as Octyl acetate (cas: 112-14-1Related Products of 112-14-1).
Octyl acetate (cas: 112-14-1) belongs to esters. Esters are widespread in nature and are widely used in industry. In nature, fats are in general triesters derived from glycerol and fatty acids. Esters are responsible for the aroma of many fruits. Esters are more polar than ethers but less polar than alcohols. They participate in hydrogen bonds as hydrogen-bond acceptors, but cannot act as hydrogen-bond donors, unlike their parent alcohols. This ability to participate in hydrogen bonding confers some water-solubility.Related Products of 112-14-1
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics