Category: 111-79-5

The important role of 111-79-5

Researchers who often do experiments know that organic synthesis is a process of preparing more complex target molecules from simple raw materials through one or more chemical reactions. Generally, it requires fewer steps, and cheap raw materials. 111-79-5, name is Methyl non-2-enoate, A new synthetic method of this compound is introduced below., Recommanded Product: 111-79-5

Researchers who often do experiments know that organic synthesis is a process of preparing more complex target molecules from simple raw materials through one or more chemical reactions. Generally, it requires fewer steps, and cheap raw materials. 111-79-5, name is Methyl non-2-enoate, A new synthetic method of this compound is introduced below., Recommanded Product: 111-79-5

PREPARATION 2 4-Nitro-beta-hexyl-1H-imidazole-1-propanoic acid methyl ester The title intermediate was prepared by combining 5.0 grams of 4-nitroimidazole, 8.26 g of methyl 2-nonenate, 4.08 g of sodium bicarbonate, and 200 ml of dimethylformamide and heating the mixture at 80 C. for 18 hours. After cooling, the mixture was poured into water and extracted into ethyl acetate. The organic layer was concentrated in vacuo and the residue purified by HPLC over a silica column eluding with ethyl acetate. The appropriate fractions were combined and concentrated in vacuo to provide 2.2 g of the desired titled intermediate. Analysis for C13 H21 N3 O4: Calc.: C, 55.11; H, 7.47; N, 14.83; Found: C, 55.37; H, 7.37; N, 14.58.

The basis of chemical reaction formula synthesis, the synthesis route is composed of some specific reactions and combined according to certain logical thinking. We look forward to the emergence of more reaction modes in the future.

Reference:
Patent; Eli Lilly and Company; US5073566; (1991); A;,
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Continuously updated synthesis method about Methyl non-2-enoate

In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 111-79-5, name is Methyl non-2-enoate belongs to esters-buliding-blocks compound, it is a common compound, a new synthetic route is introduced below. Recommanded Product: 111-79-5

In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 111-79-5, name is Methyl non-2-enoate belongs to esters-buliding-blocks compound, it is a common compound, a new synthetic route is introduced below. Recommanded Product: 111-79-5

[0080] Example 7 – Hydrogenation of esters using complexes 1[0081] tBuOK (15 mg, 0.13 mmol) was added to a solution of complex 1 (51 mg, 0.10 mmol) in 10 mL of THF and the mixture was stirred for 3 min. 1 mL of the obtained solution was mixed with methyl benzoate (2.72 g, 20.0 mol) or other desired substrate in 6 mL of THF or toluene. The mixture was then placed into a 75 mL stainless-steel reactor (Parr 4740) equipped with a magnetic stir bar. The reactor was purged by two cycles of pressurizati on/venting with H2 (150 psi, 10 Bar) and then pressurized with H2 (725 psi, 50 Bar) and disconnected from the H2 source. The reaction was conducted for 1.5 h at 100 C in a preheated oil bath. At the end of the reaction time, the reactor was placed into a cold water bath and it was depressurized after cooling to the ambient temperature. The product benzyl alcohol was obtained after evaporation of all volatiles (THF, CH3OH) under vacuum. The results are shown in tables 1-4 below. See table 2 for a complete list of tested substrates.

The synthetic route of 111-79-5 has been constantly updated, and we look forward to future research findings.

Reference:
Patent; GOUSSEV, Dmitri; SPASYUK, Denis; WO2013/23307; (2013); A1;,
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics