Category: 110928-44-4

Related Products of 110928-44-4, In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 110928-44-4, name is trans-Methyl 4-(hydroxymethyl)cyclohexanecarboxylate belongs to esters-buliding-blocks compound, it is a common compound, a new synthetic route is introduced below.

c) Synthesis of /nms- -chloromethyQ Cyclohexane-1 -carboxylic acid methyl ester: jCMX-OMej The hydroxymethyl methyl ester (4 mMole) obtained above is dissolved in chloroform and chilled to – 10. To the chilled solution of the alcohol is added thionylchloride ( 10 mMole) in aliquots over 30min., following which the stirred reaction mixture is allowed to come to room temperature, and left overnight. The reaction mixture is poured in to water ( l OOmL), and extracted with chloroform, dried over magnesium sulfate and the solvent removed by evaporation to provide the chloromethyl ester.

The synthetic route of trans-Methyl 4-(hydroxymethyl)cyclohexanecarboxylate has been constantly updated, and we look forward to future research findings.

Reference:
Patent; THROMBOLTYICS, LLC; CHIBBER, Bakshy, A.; (41 pag.)WO2016/73493; (2016); A2;,
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Synthetic Route of 110928-44-4, In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 110928-44-4, name is trans-Methyl 4-(hydroxymethyl)cyclohexanecarboxylate belongs to esters-buliding-blocks compound, it is a common compound, a new synthetic route is introduced below.

To a solution of compound 14 ( 17.26 g) in THF (450 ml_) stirred at 0 C was added triethylamine (39.4 ml284.5 mmol) followed by methanesulfonyl chloride (14.9 ml151.7 mmol). The mixture was stirred at 0 C for additional 10 min then the reaction mixture was stirred at room temperature for 2 h . The reaction mixture was filtered through a Celite (0,01-0,04 mm) bed that was then washed with fresh TH F; the resulting solution was evaporated under reduced pressure to give 15 as a yellow oil (30.95 g) that was employed in the following reaction without further purification. Quantitative yield . Analytical data : Mr: 250.30 (C10H 18O5S) and 13C-NMR and MS are compatible with the structure

In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles, trans-Methyl 4-(hydroxymethyl)cyclohexanecarboxylate, other downstream synthetic routes, hurry up and to see.

Reference:
Patent; BRACCO IMAGING SPA; MAIOCCHI, Alessandro; VISIGALLI, Massimo; BELTRAMI, Lorena; SINI, Loredana; LATTUADA, Luciano; WO2013/135750; (2013); A1;,
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics