Sokolov, Jan; Stefek, Adam; Sindelar, Vladimir published an article in ChemPlusChem. The title of the article was 《Functionalized Chiral Bambusurils: Synthesis and Host-Guest Interactions with Chiral Carboxylates》.Name: (R)-Methyl 4-(1-aminoethyl)benzoate hydrochloride The author mentioned the following in the article:
Bambusurils are a class of macrocyclic anion receptors that exhibit notable anion recognition properties, able to bind various inorganic anions as well the carboxylates or sulfonates. Recently, enantioselective recognition of chiral carboxylates using non-functionalized chiral bambusuril derivatives was reported. Herein, synthesis and host-guest properties of two new representatives of chiral bambusuril macrocycles bearing ester functional groups, differing by the substituents attached to their portals was reported. Their supramol. properties in terms of carboxylate binding were studied by means of NMR in DMSO-d6. The reported bambusurils bind to selected chiral carboxylates with enantioselectivity factors up to 3.1. The results indicated that the selectivity towards different carboxylates is governed by the steric constraint of the substituents surrounding bambusuril portals. No clear trend in the binding affinities and their enantioselectivities was found. The experimental part of the paper was very detailed, including the reaction process of (R)-Methyl 4-(1-aminoethyl)benzoate hydrochloride(cas: 1097196-96-7Name: (R)-Methyl 4-(1-aminoethyl)benzoate hydrochloride)
(R)-Methyl 4-(1-aminoethyl)benzoate hydrochloride(cas: 1097196-96-7) belongs to anime. Aniline, ethanolamines, and several other amines are major industrial commodities used in making rubber, dyes, pharmaceuticals, and synthetic resins and fibres and for a host of other applications. Most of the numerous methods for the preparation of amines may be broadly divided into two groups: (1) chemical reduction (replacement of oxygen with hydrogen atoms in the molecule) of members of several other classes of organic nitrogen compounds and (2) reactions of ammonia or amines with organic compounds.Name: (R)-Methyl 4-(1-aminoethyl)benzoate hydrochloride
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