Category: 106-02-5

Weeks, John;Li, Albert P.;Doshi, Utkarsh;Johanning, Karla;Guiney, Patrick D. published 《In vitro evaluation of the metabolic stability of nine fragrance chemicals in trout and human hepatocytes》. The research results were published in《Journal of Applied Toxicology》 in 2020.Formula: C15H28O2 The article conveys some information:

In vitro metabolic stability of nine fragrance chems.: p-tolyl acetate, cashmeran, ethylene brassylate, celestolide, galaxolide, traseolide, ambretone, tonalide and pentadecanolide, was evaluated in trout and human hepatocytes. The compounds were incubated with trout hepatocytes at 12°C and human hepatocytes at 37°C. Quantification of compound disappearance with time was performed using gas chromatog./mass spectrometry. in vivo hepatic intrinsic clearance values were calculated from the in vitro data. Significant metabolism was observed with trout hepatocytes for five of the nine fragrance chems., while all nine were metabolized significantly with human hepatocytes. Previously published models were used to examine expected bioaccumulation and persistence in whole organisms. Calculated half-lives due to metabolism of the nine chems. are significantly shorter for humans than trout: <1 h and <1 day, resp. For all chems. with demonstrated hepatic metabolism, the models indicate a lack of accumulation. For those where metabolism was demonstrated in trout, calculated bioconcentration factors would not be classified as bioaccumulative under prevailing regulatory systems.Oxacyclohexadecan-2-one (cas: 106-02-5) were involved in the experimental procedure.

Oxacyclohexadecan-2-one(cas:106-02-5) is a natural product found in Lonicera japonica and Angelica archangelica.Formula: C15H28O2 It is a macrocyclic lactone that can be used as a flavoring agent and fragrance ingredient due to its musk flavor/odor.

Reference:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Related Products of 106-02-5In 2022, Kazemi Targhi, Negar;Tavakoli, Omid;Nazemi, Ali Hekmat published 《Co-pyrolysis of lentil husk wastes and Chlorella vulgaris: Bio-oil and biochar yields optimization》. 《Journal of Analytical and Applied Pyrolysis》published the findings. The article contains the following contents:

The ever-increasing demand for fossil fuels has led to environmental issues and depletion of energy resources, as a consequence, a growing interest in biomass as a promising renewable and sustainable feedstock for biofuels production is developing. In this work, lentil husks (agricultural wastes) and Chlorella vulgaris (microalgae) were selected to investigate their interaction during co-pyrolysis process. Using a response surface methodol. (RSM), a series of experiments were designed and carried out in a fixed bed reactor varying the temperature of 400-600°;C, heating rate of 5-25°;C/min and algae to husk blend ratios of 0, 25, 50, 75, 100 wt% at constant flow rate of argon carrier gas, 0.4 L min-1. The yield of Bio-oil and biochar as co-pyrolysis products were studied both quant. and qual. The results unraveled a significant improvement on bio-oil yield by addition of C. vulgaris to lentil husk. Bio-oil yield increased from 13.8% to 20.8% by increasing algae content from 0% to 100% (T = 500°;C, HR = 15°;C min-1). While at T = 600°;C, the gas yield increased to 40.15%. and lower temperature (400°;C), favored biochar formation (39.5%), finally optimization results could lead to bio-oil yield of 18% (T = 479°;C, HR = of 16°;C min-1, R = 54%). The quality of the product at optimized level was featured by a rise in the carbon and a decrease in the oxygen content of bio-oil, and a bio-oil with improved higher heating value was obtained. The results of volatile products analyzed by Gas chromatog.-mass spectrometry (GC-MS) showing that, the co-pyrolytic oil was rich in alkanes and aromatics compounds Synergistical interactions between C. vulgaris and lentil husk, showed that alcs., ketones and esters went through a remarkable reduction and phenols formation as valuable chem. compounds was improved. To complete the study, the researchers used Oxacyclohexadecan-2-one (cas: 106-02-5) .

Oxacyclohexadecan-2-one(cas:106-02-5) is a monomer used to make PGA-co-pentadecalactone polymers to be used in the development of directly compressed prolonged release tablets of slightly soluble drugs such as ketoprofen.Related Products of 106-02-5It may be used for the synthesis of poly(pentadecanolide) (PPDL) by Novozyme 435 catalyzed ring-opening polymerization.

Reference:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Naddeo, Marco;Vigliotta, Giovanni;Pellecchia, Claudio;Pappalardo, Daniela published 《Synthesis of bio-based polymacrolactones with pendant eugenol moieties as novel antimicrobial thermoplastic materials》 in 2020. The article was appeared in 《Reactive & Functional Polymers》. They have made some progress in their research.Related Products of 106-02-5 The article mentions the following:

In the last few decades there has been a continuous effort toward the synthesis of polymers from renewable resources. In this context we have presently developed novel and fully bio-based functionalized polymacrolactones bearing pendant eugenol moieties. These polymeric materials were obtained by exploiting the ring-opening copolymerization of two macrolactones, ω-6-hexadecenlactone (6HDL) and ω-pentadecalactone (PDL), both derived from renewable resources, in the presence of a pyridylamidozinc(II) complex, to produce random poly(6HDL-co-PDL) copolymers. Eugenol, a natural occurring essential oil with anti-microbial properties, was modified in its mercapto derivative, the 4-(3-mercaptopropyl)-2-methoxyphenol (TE). Subsequently, the thiol-ene addition reaction of the TE to the C-C double bond of the 6HDL monomeric units of the poly(6HDL-co-PDL) copolymers produced the functionalized polymacrolactones with pendant eugenol moieties. The melting temperatures and the thermal degradation behavior of the TE-functionalized copolymers were dependent on the copolymers composition The antimicrobial activity of TE-functionalized copolymers was tested for the bacterium E. coli on films. The toxicity of the samples was dependent on the amount of TE groups in the films. Our approach demonstrated the feasibility to covalently attach eugenol moieties to a polymacrolactone main chain and to impart antimicrobial properties to the macromol. chains.Oxacyclohexadecan-2-one (cas: 106-02-5) were involved in the experimental procedure.

Oxacyclohexadecan-2-one(cas:106-02-5) is a monomer used to make PGA-co-pentadecalactone polymers to be used in the development of directly compressed prolonged release tablets of slightly soluble drugs such as ketoprofen.Related Products of 106-02-5It may be used for the synthesis of poly(pentadecanolide) (PPDL) by Novozyme 435 catalyzed ring-opening polymerization.

Reference:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Reference of Oxacyclohexadecan-2-oneIn 2020, Polloni, Andre E.;Chiaradia, Viviane;do Amaral, Ronaldo Jose F. C.;Kearney, Cathal;Gorey, Brian;de Oliveira, Debora;de Oliveira, Jose V.;de Araujo, Pedro H. H.;Sayer, Claudia;Heise, Andreas published 《Polyesters with main and side chain phosphoesters as structural motives for biocompatible electrospun fibres》. 《Polymer Chemistry》published the findings. The article contains the following contents:

Phosphoester containing polymers are promising materials in biomedical applications due to their biocompatibility and biodegradability. Utilizing thiol-ene chem., the synthesis of two novel structural polymer motives combining polyesters and phophoester groups was explored. The first polymer was obtained by coupling ene-functional poly(thioether-phosphoester) with thiol functional poly(pentadecalactone). While the coupling reaction was successful, yields remained low presumably due to inadequate endgroup stoichiometry. The second polymer comprised phosphoester side groups conjugated to unsaturated poly(globalide). Double bond conversions up to 84% were achieved depending of the type of phosphoester thiol and relative reactant ratios. The resulting polymers transitioned from solid semicrystaline to liquid amorphous with increasing degree of phosphoester conjugation. Electrospun fibers from polymers with 14% phosphoester conjugation allowed attachment and survival of human dermal fibroblasts, indicating their biocompatibility. These polymers represent a new class of easily accessible biocompatible polyester-phosphoester hybrid materials as potential building blocks for tunable biomaterials.Oxacyclohexadecan-2-one (cas: 106-02-5) were involved in the experimental procedure.

Oxacyclohexadecan-2-one(cas:106-02-5) is a natural product found in Lonicera japonica and Angelica archangelica.Reference of Oxacyclohexadecan-2-one It is a macrocyclic lactone that can be used as a flavoring agent and fragrance ingredient due to its musk flavor/odor.

Reference:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Li, Min;Zhang, Pan;Chen, Changle published 《Light-Controlled Switchable Ring Opening Polymerization》 in 2019. The article was appeared in 《Macromolecules (Washington, DC, United States)》. They have made some progress in their research.Reference of Oxacyclohexadecan-2-one The article mentions the following:

Salicylaldimine Zn(II) complexes bearing azobenzene moieties were prepared and characterized. Isomerization between the trans and cis forms of these complexes was achieved by exposure to light; both isomers were active in ring-opening polymerizations of ε-caprolactone (CL), rac-lactide, trimethylene carbonate, β-oxetanone, δ-valerolactone, cyclopentadecanolide, and 5-methyl-5-propyl-1,3-dioxan-2-one but exhibited different kinetic profiles. A 6-fold reactivity difference was realized for the ring-opening polymerization of CL upon irradiation with light. The light-induced isomerization also led to reactivity discrimination between different monomers in copolymerization reactions. Reversible photoswitching between two catalytically active states provides a strategy for the control of polymerization processes, as well as the compositions of the polymers produced. The experimental procedure involved many compounds, such as Oxacyclohexadecan-2-one (cas: 106-02-5) .

Oxacyclohexadecan-2-one(cas:106-02-5) is a monomer used to make PGA-co-pentadecalactone polymers to be used in the development of directly compressed prolonged release tablets of slightly soluble drugs such as ketoprofen.Reference of Oxacyclohexadecan-2-oneIt may be used for the synthesis of poly(pentadecanolide) (PPDL) by Novozyme 435 catalyzed ring-opening polymerization.

Reference:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Computed Properties of C15H28O2In 2021, Demir Kanbur, Esra;Yuksek, Turan;Atamov, Vagif;Ozcelik, Ali Erdem published 《A comparison of the physicochemical properties of chestnut and highland honey: The case of Senoz Valley in the Rize province of Turkey》. 《Food Chemistry》published the findings. The article contains the following contents:

The aim of this study was to determine the physicochem. parameter changes, aroma, melissopalynol. properties, and heavy metal content of honey produced from different types of flora (chestnut and highland) in the Senoz Valley. For this purpose, the distribution of beehives at different elevation levels in the research area was determined by a layered random sampling method. Some characteristics of the honey samples were analyzed by standard laboratory methods. The highest average color (L and b) and the glucose, sucrose, Brix, Cd, Pb, Ni, Zn, and Cr values were found in the highland honeys; the highest color (a) and fructose, F/G ratio, proline, pH, conductivity, Fe, Cu, Al, and Mn values were found in the chestnut honeys. The difference between highland and chestnut honeys was statistically significant in terms of color (L and a), F/G ratio, proline, pH, elec. conductivity, Pb, Cu, and Mn. A total of 146 aromatic components were isolated in the chestnut and highland honeys.Oxacyclohexadecan-2-one (cas: 106-02-5) were involved in the experimental procedure.

Oxacyclohexadecan-2-one(cas:106-02-5) is a monomer used to make PGA-co-pentadecalactone polymers to be used in the development of directly compressed prolonged release tablets of slightly soluble drugs such as ketoprofen.Computed Properties of C15H28O2It may be used for the synthesis of poly(pentadecanolide) (PPDL) by Novozyme 435 catalyzed ring-opening polymerization.

Reference:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Quality Control of Oxacyclohexadecan-2-one《Quadruple-shape hydrogels》 was published in 2019. The authors were Balk, Maria;Behl, Marc;Lendlein, Andreas, and the article was included in《Smart Materials and Structures》. The author mentioned the following in the article:

The capability of directed movements by two subsequent shape changes could be implemented in shape-memory hydrogels by incorporation of two types of crystallizable side chains. While in nonswollen polymer networks even more directed movements could be realized, the creation of multishape hydrogels is still a challenge. We hypothesize that a quadruple-shape effect in hydrogels can be realized, when a swelling capacity almost independent of temperature is generated, whereby directed movements could be enabled, which are not related to swelling. In this case, entropy elastic recovery could be realized by hydrophilic segments and the fixation of different macroscopic shapes by means of three semi-crystalline side chains generating temporary crosslinks. Monomethacrylated semicrystalline oligomers were connected as side chains in a hydrophilic polymer network via radical copolymerization Computer assisted modeling was utilized to design a demonstrator capable of complex shape shifts by creating a casting mold via 3D printing from polyvinyl alc. The demonstrator was obtained after copolymerization of polymer network forming components within the mold, which was subsequently dissolved in water. A thermally-induced quadruple-shape effect was realized after equilibrium swelling of the polymer network in water. Three directed movements were successfully obtained when the temperature was continuously increased from 5°C to 90°C with a recovery ratio of the original shape above 90%. Hence, a thermally-induced quadruple-shape effect as new record for hydrogels was realized. Here, the temperature range for the multi-shape effect was limited by water as swelling media (0°C-100°C), simultaneously distinctly separated thermal transitions were required, and the overall elasticity indispensable for successive deformations was reduced as result of partially chain segment orientation induced by swelling in water. Conclusively the challenges for penta- or hexa-shape gels are the design of systems enabling higher elastic deformability and covering a larger temperature range by switching to a different solvent. The experimental procedure involved many compounds, such as Oxacyclohexadecan-2-one (cas: 106-02-5) .

Oxacyclohexadecan-2-one(cas:106-02-5) is a monomer used to make PGA-co-pentadecalactone polymers to be used in the development of directly compressed prolonged release tablets of slightly soluble drugs such as ketoprofen.Quality Control of Oxacyclohexadecan-2-oneIt may be used for the synthesis of poly(pentadecanolide) (PPDL) by Novozyme 435 catalyzed ring-opening polymerization.

Reference:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Synthetic Route of C15H28O2In 2021, Kalana, U. L. D. Inush;Datta, Partha P.;Hewawasam, Rukshika S.;Kiesewetter, Elizabeth T.;Kiesewetter, Matthew K. published 《Organocatalytic ring-opening polymerization of thionolactones: anything O can do, S can do better》. 《Polymer Chemistry》published the findings. The article contains the following contents:

The H-bond mediated organocatalytic ring-opening polymerizations (ROPs) of four new thionolactone monomers are discussed. The kinetic and thermodn. behavior of the ROPs is considered in the context of the parent lactone monomers. Organocatalysts facilitate the retention of the S/O substitution as well as the synthesis of copolymers. The thionoester moieties in the polymer backbone serve as a chem. handle for a facile crosslinking reaction, and the porosity of the resulting crosslinked polymer can be tuned by altering the thioester d. in the (co)polymer. The crosslinked polymers are shown to be degradable in water, and an Au³⁺ recovery application is demonstrated. The experimental procedure involved many compounds, such as Oxacyclohexadecan-2-one (cas: 106-02-5) .

Oxacyclohexadecan-2-one(cas:106-02-5) is a natural product found in Lonicera japonica and Angelica archangelica.Synthetic Route of C15H28O2 It is a macrocyclic lactone that can be used as a flavoring agent and fragrance ingredient due to its musk flavor/odor.

Reference:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Martinez-Cutillas, Alfredo;Leon, Salvador;Oh, Sejin;Martinez de Ilarduya, Antxon published 《Enzymatic recycling of polymacrolactones》 in 2022. The article was appeared in 《Polymer Chemistry》. They have made some progress in their research.Quality Control of Oxacyclohexadecan-2-one The article mentions the following:

The use of renewable monomers to make new polyesters which could replace the ones obtained from petrochem. resources employing green processes is attracting a lot of attention these days. With this in mind, three different macrolactones, ω-pentadecalactone, globalide and 6-hexadecenlactone, have been polymerized in bulk by enzymic ring opening polymerization (e-ROP) using immobilized Candida antarctica lipase B to give their corresponding polymacrolactones (PMLs). For the first time, these PMLs have been depolymerized enzymically in solution with the concourse of the same enzyme and at mild temperatures GPC, NMR and ESI MS demonstrated that the main products recovered after the enzymic processive recycling were cyclic monomers and dimers, with a small amount of higher size macrocyclic oligoesters (MCOs). It was observed that these depolymerizations followed a Michaelis-Menten kinetic model. Finally it was shown that these MCOs could be repolymd. This research provides a biosynthetic method for chem. recycling of these interesting polymeric materials providing a pathway towards a circular economy. And Oxacyclohexadecan-2-one (cas: 106-02-5) was used in the research process.

Oxacyclohexadecan-2-one(cas:106-02-5) is a natural product found in Lonicera japonica and Angelica archangelica.Quality Control of Oxacyclohexadecan-2-one It is a macrocyclic lactone that can be used as a flavoring agent and fragrance ingredient due to its musk flavor/odor.

Reference:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Computed Properties of C15H28O2《Phytochemical profile and biological activity of endemic Sideritis sipylea Boiss. in North Aegean Greek islands》 was published in 2020. The authors were Axiotis, Evangelos;Petrakis, Eleftherios A.;Halabalaki, Maria;Mitakou, Sofia, and the article was included in《Molecules》. The author mentioned the following in the article:

Sideritis sipylea Boiss. is an endemic plant of the Mediterranean basin that is distributed in the Greek islands of the North Aegean Sea, i.e., Lesvos, Chios, Samos, and Ikaria, and in the West and Middle peninsula of Turkey. It is considered an endangered species because of its uncontrolled collection from its original habitat. Although the antioxidant, anti-inflammatory and antimicrobial properties have been previously reported, the total chem. profile has not yet been explored. In this context, the chem. profiles of the water/methanol (HA), methanol (ME), and Et acetate (EtOAc) extracts were analyzed using ultra-performance liquid chromatog. coupled with high-resolution mass spectrometry (UPLC-HRMS). In parallel, anal. by gas chromatog.-mass spectrometry (GC-MS) was employed for the dichloromethane extract (DCM) as well as for the essential oil (EO) and the extract obtained by supercritical fluid extraction (SFE). Furthermore, the total phenolic content (TPC) along with the in vitro tyrosinase and elastase enzyme inhibitory activity of different extracts was evaluated, towards the discovery of new active agents for cosmetic formulations. These activities are in accordance with its well-known antioxidant and anti-inflammatory properties, confirming the importance of ethnopharmacol. references for S. sipylea in Greece and Turkey. The experimental procedure involved many compounds, such as Oxacyclohexadecan-2-one (cas: 106-02-5) .

Oxacyclohexadecan-2-one(cas:106-02-5) is a natural product found in Lonicera japonica and Angelica archangelica.Computed Properties of C15H28O2 It is a macrocyclic lactone that can be used as a flavoring agent and fragrance ingredient due to its musk flavor/odor.

Reference:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics