Category: 10472-24-9

On March 6, 2020, Kabes, Connor Q.; Maximuck, William J.; Ghosh, Subrata K.; Kumar, Anil; Bhuvanesh, Nattamai; Gladysz, John A. published an article.Related Products of 10472-24-9 The title of the article was Chiral Tricationic Tris(1,2-diphenylethylenediamine) Cobalt(III) Hydrogen Bond Donor Catalysts with Defined Carbon/Metal Configurations; Matched/Mismatched Effects upon Enantioselectivities with Enantiomeric Chiral Counter Anions. And the article contained the following:

The enantiopure and diastereopure salts Λ- or Δ-[Co((S,S)-dpen)3]3+ 2Cl-BArf- (Λ- or Δ-(S,S)-13+ 2Cl-BArf-; dpen/BArf = 1,2-diphenylethylenediamine/B(3,5-C6H3(CF3)2)4) and Λ-(S,S)-13+ 3Cl- are treated with salts of the enantiopure chiral monoanions (A-) or dianions (A2-) 3-bromocamphor-8-sulfonate (camphSO3-), 1,1′-binaphthyl-2,2′-diyl phosphate (and three 3,3′-disubstituted derivatives), a related biphenanthryl species, tartrate, and Sb2(tart’)22- (tart’ = [-O2C-CHO–CHO–CO2-]). The lipophilic salts Λ- or Δ-(S,S)-13+ 2A-BArf-, Λ-(S,S)-13+ A2-BArf-, and Λ-(S,S)-13+ 3A- are isolated as hydrates and characterized by NMR and microanalyses. In the presence of tertiary amines, many of these are highly enantioselective catalysts for additions of 1,3-dicarbonyl compounds to trans-β-nitrostyrene and di-tert-butylazodicarboxylate. The ee values for diastereomeric salts can exhibit significant differences (avg/high/median Δ%ee = 10/63/6; matched/mismatched effect), and in a few cases, they are better than those obtained with Λ- or Δ-(S,S)-13+ 2Cl-BArf-. The crystal structure of Δ-(S,S)-13+ 2(1S)-camphSO3-BArf- shows that the two sulfonate moieties H-bond to opposite (idealized) C3-sym. faces of the trication, with a sep. O atom associated with each of the three syn-periplanar NH groups. The experimental process involved the reaction of Methyl 2-cyclopentanonecarboxylate(cas: 10472-24-9).Related Products of 10472-24-9

The Article related to crystal structure enantiopure cobalt phenylethylenediamine bromocamphorsulfonate, cobalt phenylethylenediamine chiral preparation enantioselective addition catalyst dicarbonyl compound and other aspects.Related Products of 10472-24-9

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Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Niedbala, Patryk; Majdecki, Maciej; Grodek, Piotr; Jurczak, Janusz published an article in 2022, the title of the article was H-Bond Mediated Phase-Transfer Catalysis: Enantioselective Generating of Quaternary Stereogenic Centers in β-Keto Esters.COA of Formula: C7H10O3 And the article contains the following content:

In this work, the development of a highly optimized method for generating the quaternary stereogenic centers in β-keto esters I (R = Me, i-Pr, t-Bu; R1 = H, 2-Me, 3-Me, 4-Me, 4-Cl; R2 = R3 = H; R2R3 = -CH=CH-CH=CH-) was presented. This enantioselective phase-transfer alkylation catalyzed by hybrid Cinchona catalysts II (R4 = naphthalen-2-yl, naphthalen-1-yl, quinolin-8-yl) allows for the efficient generation of the optically active products I with excellent enantioselectivity, using only 1 mol% of the catalyst. The vast majority of phase-transfer catalysts in asym. synthesis work is made by creating ionic pairs with the nucleophile-attacking anionic substrate. Therefore, it is a sensible approach to search for new methodologies capable of introducing functional groups into the precursor’s structure, maintaining high yields and enantiomeric purity. The experimental process involved the reaction of Methyl 2-cyclopentanonecarboxylate(cas: 10472-24-9).COA of Formula: C7H10O3

The Article related to benzyl keto ester preparation enantioselective, keto ester benzyl bromide alkylation phase transfer catalyst, cinchona catalysts, alkylation, enantioselectivity, organocatalysis, phase-transfer catalysis and other aspects.COA of Formula: C7H10O3

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

On May 25, 2020, Abdelkawy, Mahmoud A.; Aly, El-Saied A.; El-Badawi, Mahmoud A.; Itsuno, Shinichi published an article.Name: Methyl 2-cyclopentanonecarboxylate The title of the article was Synthesis of Cinchona Urea Polymers and Their Evaluation as Catalyst in the Asymmetric Reactions. And the article contained the following:

Chiral polyureas of cinchona alkaloids were synthesized via repetitive Mizoroki-Heck (MH) coupling reaction. The Pd-catalyzed polycondensation of cinchona urea dimers and 1,4-diiodobenzene afforded the chiral polyureas. The catalytic activity of the chiral polymers was subsequently investigated. The asym. Michael addition of ketoesters such as Me 2-oxocyclopentanecarboxylate, acetylacetone to nitroolefins (E)-ArCH=CHNO2 (Ar = Ph, 4-methylphenyl, 4-fluorophenyl, thiophen-2-yl) was successfully catalyzed by the polymeric organocatalysts to give the corresponding Michael adducts I and with 3-[(1S)-2-nitro-1-phenylethyl]pentane-2,4-dione high catalytic activities and excellent enantioselectivities (up to >99% ee). The polymeric catalysts were insoluble in commonly used organic solvents. They were easily recovered and reused several times without any loss of the catalytic activity. The experimental process involved the reaction of Methyl 2-cyclopentanonecarboxylate(cas: 10472-24-9).Name: Methyl 2-cyclopentanonecarboxylate

The Article related to polyurea cinchona alkaloid preparation, cinchona urea dimer diiodobenzene mizoroki heck polycondensation palladium catalyst, ketoester nitroolefin asym michael addition polyurea cinchona alkaloid catalyst and other aspects.Name: Methyl 2-cyclopentanonecarboxylate

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Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

On September 2, 2022, Wang, Zongkang; Yin, Liqiang; Wang, Mengdan; Zhu, Yilin; Yang, Yajie; Cheng, Lu; Wang, Chengyu; Li, Yanzhong published an article.Category: esters-buliding-blocks The title of the article was Selective C-O Bond Forming Reactions at Indole-C2-Position toward Polycyclic Indolone or Indolinone Derivatives Tethered with Medium-Sized Rings. And the article contained the following:

A methodol. involving the chemoselective synthesis of tetracyclic [1,3]oxazino[3,2-a]indol-4-ones I [R1 = H, 2-F, 3-Br, 1-MeO, 2-MeO; R2 = Ph, 4-FC6H4, 3-ClC6H4, etc.; R3 = CN, CO2Me, CO2Et, X = (CH2)n; n = 1, 2, 3] or tetracyclic [1,3]oxazino[3,2-a]indoline-4-ones II [R4 = Ph, 3-ClC6H4, 4-BrC6H4, etc.; R5 = CN, CO2Me, CO2Et; R6 = H, 2-F, 3-Br, 2-MeO] tethered with a medium-sized ring by cross dehydrogenative coupling (CDC) or nucleophilic addition (NA) reaction had been developed. [1,3]Oxazino[3,2-a]indol-4-one compounds fused with a medium-sized ring were constructed through a CDC reaction in the presence of I2 and K2CO3. Whereas, [1,3]oxazino[3,2-a]indoline-4-ones tethered with a medium-sized ring were obtained with a TfOH system by NA reaction. The experimental process involved the reaction of Methyl 2-cyclopentanonecarboxylate(cas: 10472-24-9).Category: esters-buliding-blocks

The Article related to tetracyclic oxazinoindolone chemoselective preparation, oxazinoindolinone tetracyclic chemoselective preparation, hydroxycycloheptadienyl indolyl methanone cross dehydrogenative coupling nucleophilic addition and other aspects.Category: esters-buliding-blocks

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

On January 26, 2022, Paulisch, Tiffany O.; Mai, Lukas A.; Strieth-Kalthoff, Felix; James, Michael J.; Henkel, Christian; Guldi, Dirk M.; Glorius, Frank published an article.Application In Synthesis of Methyl 2-cyclopentanonecarboxylate The title of the article was Dynamic Kinetic Sensitization of β-Dicarbonyl Compounds-Access to Medium-Sized Rings by De Mayo-Type Ring Expansion. And the article contained the following:

Herein, we present a photocatalyzed two-carbon ring expansion of β-dicarbonyl compounds with unactivated olefins that provides facile access to medium-sized rings. Selective sensitization of the substoichiometric enol tautomer enables reactivity of substrates incompatible with the classical De Mayo reaction conditions. Key to success was the identification of the metal-based sensitizer fac-[Ir(CF3-pmb)3], which was excited using common near-visible LEDs, and possesses a high triplet excited state energy of 73.3 kcal mol-1. This exactly falls in the range between the triplet energies of the enol and keto tautomer, thereby enabling a dynamic kinetic sensitization. Demonstrating the applicability of fac-[Ir(CF3-pmb)3] as a photocatalyst in organic synthesis for the first time, a two-step photocycloaddition-ring-opening cascade with β-ketoesters, -diketones, and -ketoamides was described. The mechanism was corroborated by time-resolved spectroscopy, as well as further exptl. and computational studies. The experimental process involved the reaction of Methyl 2-cyclopentanonecarboxylate(cas: 10472-24-9).Application In Synthesis of Methyl 2-cyclopentanonecarboxylate

The Article related to alkene cyclic dicarbonyl compound photocatalyst diastereoselective regioselective ring enlargement, dicarbonyl compound preparation, de mayo reaction, energy transfer, photochemistry, ring expansion, spectroscopy and other aspects.Application In Synthesis of Methyl 2-cyclopentanonecarboxylate

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Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Wang, Yakun; Li, Yueyun; Lian, Mingming; Zhang, Jixia; Liu, Zhaomin; Tang, Xiaofei; Yin, Hang; Meng, Qingwei published an article in 2019, the title of the article was Asymmetric α-alkylation of cyclic β-keto esters and β-keto amides by phase-transfer catalysis.Computed Properties of 10472-24-9 And the article contains the following content:

Without employing any transition metal, a highly enantioselective α-alkylation of cyclic β-keto esters and β-keto amides has been realized by phase-transfer catalysis. This improved procedure is applicable to different kinds of bromides with cinchona derivatives and gives the corresponding products e.g., I and e.g., II, in excellent enantiopurities (up to 98% ee) and good yields (up to 98%). Moreover, the reaction was scalable and the phase-transfer catalyst was recyclable. This provided an alternative and competitive method to the asym. α-alkylation of β-dicarbonyl compounds The experimental process involved the reaction of Methyl 2-cyclopentanonecarboxylate(cas: 10472-24-9).Computed Properties of 10472-24-9

The Article related to indanone preparation enantioselective, keto ester alkyl bromide alkylation cinchona phase transfer catalyst, amide keto alkyl bromide alkylation cinchona phase transfer catalyst, tetralone preparation enantioselective and other aspects.Computed Properties of 10472-24-9

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

On June 21, 2020, Paul, Melanie; Teubner, Melissa; Grimm-Lebsanft, Benjamin; Golchert, Christiane; Meiners, Yannick; Senft, Laura; Keisers, Kristina; Liebhaeuser, Patricia; Roesener, Thomas; Biebl, Florian; Buchenau, Soeren; Naumova, Maria; Murzin, Vadim; Krug, Roxanne; Hoffmann, Alexander; Pietruszka, Joerg; Ivanovic-Burmazovic, Ivana; Ruebhausen, Michael; Herres-Pawlis, Sonja published an article.COA of Formula: C7H10O3 The title of the article was Exceptional Substrate Diversity in Oxygenation Reactions Catalyzed by a Bis(μ-oxo) Copper Complex. And the article contained the following:

The enzyme tyrosinase contains a reactive side-on peroxo dicopper(II) center as catalytically active species in C-H oxygenation reactions. The tyrosinase activity of the isomeric bis(μ-oxo) dicopper(III) form has been discussed controversially. The synthesis of bis(μ-oxo) dicopper(III) species [Cu2(μ-O)2(L1)2](X)2 ([O1](X)2, X = PF6-, BF4-, OTf-, ClO4-), stabilized by the new hybrid guanidine ligand 2-(2-((dimethylamino)methyl)phenyl)-1,1,3,3-tetramethylguanidine (L1), and its characterization by UV/Vis, Raman, and XAS spectroscopy, as well as cryo-UHR-ESI mass spectrometry, are described. The highlight selective oxygenation of a plethora of phenolic substrates such as 1H-indol-7-ol, naphthalen-1-ol, pyridin-4-ol, etc. mediated by [O1](PF6)2, results in mono- and bicyclic quinones such as 3,4-pyridinedione, 1,2-naphthalenedione, 1H-indole-6,7-dione and provides an attractive strategy for designing new phenazines e.g., benzo[a]phenazine. The selectivity is predicted by using the Fukui function, which is hereby introduced into tyrosinase model chem. The bioinspired catalysis harnesses mol. dioxygen for organic transformations and achieves a substrate diversity reaching far beyond the scope of the enzyme. The experimental process involved the reaction of Methyl 2-cyclopentanonecarboxylate(cas: 10472-24-9).COA of Formula: C7H10O3

The Article related to phenazine preparation, quinone preparation phenylenediamine condensation copper complex catalyst, aryl alc oxygenation copper complex catalyst, copper catalysis, dioxygen activation, guanidines, phenazines, tyrosinase and other aspects.COA of Formula: C7H10O3

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Taleb, Assya; Lahrech, Mokhtar; Hacini, Salih; Thibonnet, Jerome; Parrain, Jean-Luc published an article in 2019, the title of the article was RCM vs Oxacycloisomerization through Divergent Reactivity of Dienyl- or Ynenylcycloalkanols using Grubbs Catalyst: an Access to Carbobicycles and Fused Bicyclic Dihydrofurans.Electric Literature of 10472-24-9 And the article contains the following content:

Starting from simple cyclic 1,3-ketoesters like methyl-1-allyl-2-oxocyclopentane-1-carboxylate, ethyl-1-allyl-2-oxocycloheptane-1-carboxylate and ethyl-2-oxo-1-(prop-2-ynyl)cyclohexane-1-carboxylate, etc. a three-step sequence including allylic or propargylic allylation, 1,2-addition reaction of functional Grignard reagent and alkylidene ruthenium-catalyzed cyclization yields to carbobicycles I (R = Me, Et; Q = (CH2)n, n = 1, 2, 3; Y = (CH2)m, m = 0, 1, 2) and/or bicyclic dihydrofurans II (R = Me, Et; Q = (CH2)n, n = 1, 2, 3; Y = (CH2)m, m = 0, 1, 2) or III (R = Me, Et; Q = (CH2)n, n = 1, 2, 3; Y = (CH2)m, m = 0, 1, 2) depending on the nature of theinsatn. (diene or enyne). If the classical ene-ene ring closing metathesis is observed with dienyl substituents IV (R1 = vinyl), similar enynes IV (R1 = ethynyl) led to enyne ring closing metathesis or oxacycloisomerization products depending on the chain length. In the case of ene-yne systems with appropriate longer carbon chains, under the same conditions, metathesis reactions give access to bicyclic dihydrofurans through oxacycloisomerization, demonstrating that it is possible to orient the activity of the Grubbs reagent. The experimental process involved the reaction of Methyl 2-cyclopentanonecarboxylate(cas: 10472-24-9).Electric Literature of 10472-24-9

The Article related to carbobicycle preparation, dienyl cycloalkanol cyclization grubbs catalyst, bicyclo dihydrofuran preparation diastereoselective, diynenyl cycloalkanol cyclization grubbs catalyst, enynyl cycloalkanol cyclization grubbs catalyst and other aspects.Electric Literature of 10472-24-9

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Ping, Yuan-Ji; Zhou, Yi-Ming; Wu, Liang-Liang; Li, Zong-Rui; Gu, Xin; Wan, Xiao-Long; Xu, Zhen-Jiang; Che, Chi-Ming published an article in 2021, the title of the article was Fe-BPsalan complex catalyzed highly enantioselective Diels-Alder reaction of alkylidene β-ketoesters.Synthetic Route of 10472-24-9 And the article contains the following content:

A practical, highly efficient iron-catalyzed asym. Diels-Alder reaction of various alkylidene β-ketoesters with dienes was developed. Both cyclic and acyclic alkylidene β-ketoesters underwent the reaction well with the Fe-BPsalan complex as the catalyst to afford the addition products including estrone analogs in excellent yields, good to high diastereoselectivities and excellent enantioselectivities under mild reaction conditions. DFT calculations revealed the critical role of the steric effect in directing the reaction selectivity. The experimental process involved the reaction of Methyl 2-cyclopentanonecarboxylate(cas: 10472-24-9).Synthetic Route of 10472-24-9

The Article related to iron bipyrrolindine salan complex catalyst preparation, alkylidene ketoester vinylalkene iron complex enantioselective diels alder reaction, butadiene alkylidene ketoester iron complex enantioselective diels alder reaction and other aspects.Synthetic Route of 10472-24-9

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Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

On September 30, 2019, Chhanda, Sadia Afrin; Itsuno, Shinichi published an article.Product Details of 10472-24-9 The title of the article was Design and synthesis of chiral hyperbranched polymers containing cinchona squaramide moieties and their catalytic activity in the asymmetric Michael addition reaction. And the article contained the following:

Chiral hyperbranched polymers (HBP) containing cinchona alkaloids were synthesized using a Mizoroki-Heck (MH) coupling polymerization reaction between a cinchona squaramide dimer and tri- or tetra-substituted aromatic iodides. This was a new type of polymeric chiral organocatalyst. We found that the as-obtained chiral HBPs show excellent catalytic activity in the asym. Michael reaction. Almost perfect enantioselectivity (>99% ee) was achieved in the reaction of β-ketoester and trans-β-nitrostyrene. The three-dimensional network structure of the chiral HBPs is structurally robust and can be reused for further reaction without any loss in their catalytic activity. The experimental process involved the reaction of Methyl 2-cyclopentanonecarboxylate(cas: 10472-24-9).Product Details of 10472-24-9

The Article related to cinchona squaramide iodoarene copolymer preparation recyclability, keto ester nitro vinylarene chiral polymer organocatalyst michael addition, alkyl aryl nitroalkyl oxo cyclopentanecarboxylate diastereoselective enantioselective preparation and other aspects.Product Details of 10472-24-9

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics