Category: 10472-24-9

On August 2, 2019, Gehringer, Matthias; Mader, Patrick; Gersbach, Philipp; Pfeiffer, Bernhard; Scherr, Nicole; Dangy, Jean-Pierre; Pluschke, Gerd; Altmann, Karl-Heinz published an article.Safety of Methyl 2-cyclopentanonecarboxylate The title of the article was Configurationally Stabilized Analogs of M. ulcerans Exotoxins Mycolactones A and B Reveal the Importance of Side Chain Geometry for Mycolactone Virulence. And the article contained the following:

Mycolactones A/B are exotoxins of Mycobacterium ulcerans that are the mol. cause of Buruli ulcer. Mycolactones A/B represent a rapidly equilibrating mixture of Z/E isomers about the C4’=C5′ double bond of the C5-side chain. Here, we describe the syntheses of mycolactone analogs with configurationally stable C5-side chains (E mimetic; Z mimetics). Based on the cytotoxicity of the analogs, the Δ4′,5′-trans isomer of mycolactones A/B appears to be the major virulence factor. The experimental process involved the reaction of Methyl 2-cyclopentanonecarboxylate(cas: 10472-24-9).Safety of Methyl 2-cyclopentanonecarboxylate

The Article related to mycolactone analog preparation cytotoxicity, Biomolecules and Their Synthetic Analogs: Other Bacterial and Fungal Metabolites and other aspects.Safety of Methyl 2-cyclopentanonecarboxylate

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

On November 22, 2021, Abdelkawy, Mahmoud A.; Davin, Christopher; Aly, El-Saied A.; El-Badawi, Mahmoud A.; Itsuno, Shinichi published an article.Application In Synthesis of Methyl 2-cyclopentanonecarboxylate The title of the article was Chiral Polyureas Derived Cinchona Alkaloids: Highly Efficient Bifunctional Organocatalysts for the Asymmetric Michael Addition Reaction. And the article contained the following:

Repetitive Mizoroki-Heck (MH) coupling polymerization was used to create novel chiral polyureas with cinchona alkaloids in the main chain. Apart from two-component polycondensation of cinchona urea dimers with diiodobenzene via MH reaction conditions, some chiral polyureas were easily polymerized under self polycondensation to yield the chiral polymers. The asym. Michael addition reaction was successfully carried out using chiral polymers derived cinchona urea. Interestingly, phenolic-based chiral polymers served as heterogeneous catalysts for the enantioselective Michael reaction, with high catalytic activity and excellent enantioselectivities (up to 99% ee). These polymeric catalysts were also stable, and they could be recycled and reused. The experimental process involved the reaction of Methyl 2-cyclopentanonecarboxylate(cas: 10472-24-9).Application In Synthesis of Methyl 2-cyclopentanonecarboxylate

The Article related to chiral polyurea cinchona alkaloid organocatalyst asym michael addition, Chemistry of Synthetic High Polymers: Organic Condensation and Step Polymerization and other aspects.Application In Synthesis of Methyl 2-cyclopentanonecarboxylate

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

On April 27, 2020, Gilbert, Nicolas; Ricard, Simon; Bergeron, Jodrey; Lambolez, Pierre; Daoust, Benoit published an article.Name: Methyl 2-cyclopentanonecarboxylate The title of the article was Synthesis of Exo- and Endocyclic Enamides Through Copper-Catalyzed Regioselective Intramolecular N-Halovinylation. And the article contained the following:

Cross-couplings between amides and 1,2-dihaloalkenes are an efficient and straightforward way to access β-haloenamides which, in turn, can be functionalized into complex, stereodefined enamide motifs. However, the intramol. version of these cross-couplings, leading to cyclic β-haloenamides, was not formally studied. The authors report a study of factors affecting the efficiency of the reaction and its selectivity between potential exo and endo cyclization products. Exo/endo selectivity is largely determined by ring strain, whether it arises from the size of the resulting ring or from the structure of the starting compound, but selectivity can also be modulated by varying reaction conditions. Finally, resulting β-haloenamides readily undergo transition metal-catalyzed reactions, making this sequence a viable way to access highly functionalized cyclic enamides. The experimental process involved the reaction of Methyl 2-cyclopentanonecarboxylate(cas: 10472-24-9).Name: Methyl 2-cyclopentanonecarboxylate

The Article related to enamide exo endocycle preparation copper catalyst regioselective intramol halovinylation, Heterocyclic Compounds (More Than One Hetero Atom): Oxazines (Including Morpholine) and other aspects.Name: Methyl 2-cyclopentanonecarboxylate

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Ganesan, Divakar; Chennapuram, Madhu; Begum, Zubeda; Seki, Chigusa; Okuyama, Yuko; Kwon, Eunsang; Uwai, Koji; Tokiwa, Michio; Tokiwa, Suguru; Takeshita, Mitsuhiro; Nakano, Hiroto published an article in 2019, the title of the article was Sugar based γ-amino alcohol organocatalyst for asymmetric michael addition of β-keto esters with nitroolefins.Category: esters-buliding-blocks And the article contains the following content:

Sugar based γ-amino alc. was used in asym. Michael addition of β-keto esters with nitroolefins for the first time affording the corresponding several chiral Michael adducts bearing quaternary chiral carbon center in moderate to good chem. yields and stereoselectivities (up to 98%, up to dr. 95:5, up to 84% ee). The experimental process involved the reaction of Methyl 2-cyclopentanonecarboxylate(cas: 10472-24-9).Category: esters-buliding-blocks

The Article related to sugar amino alc organocatalyst michael addition ketoester nitroolefin, Catalysis, Reaction Kinetics, and Inorganic Reaction Mechanisms: Catalytic Reactions and other aspects.Category: esters-buliding-blocks

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

On August 2, 2019, Maejima, Saki; Yamaguchi, Eiji; Itoh, Akichika published an article.Application of 10472-24-9 The title of the article was Visible Light/Molecular-Iodine-Mediated Intermolecular Spirolactonization Reaction of Olefins with Cyclic Ketones. And the article contained the following:

In this study, intermol. spirolactonization via an iodine/visible-light-mediated C-C/C-O bond formation reaction was developed. The developed reaction proceeded to form quaternary carbon centers via carboesterification between cyclic β-keto esters and olefins, affording spirolactone derivatives, e.g., I, in a single step. In addition, the mechanistic investigation revealed that the generation of iodine radicals from mol. iodine driven by visible-light irradiation is a crucial step. The developed reaction proceeded under milder conditions than previously reported procedures as iodine played a role of a conventional transition-metal catalyst, realizing an environmentally friendly mol. transformation. The experimental process involved the reaction of Methyl 2-cyclopentanonecarboxylate(cas: 10472-24-9).Application of 10472-24-9

The Article related to olefin cyclic ketone spirolactonization iodine visible light, spirocyclic lactone preparation, iodine visible light spirolactonization mediator, Heterocyclic Compounds (One Hetero Atom): Spiro Compounds With One Hetero Atom In Each Ring and other aspects.Application of 10472-24-9

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Xu, Xiao-Feng; Wang, Yao-Feng; Guo, Tao; Luan, Li-Kun; Liu, Shan-Shan; Xu, Bao-Hua published an article in 2022, the title of the article was Synthesis of adiponitrile from dimethyl adipate and ammonia in the vapor-phase over niobium oxide.Formula: C7H10O3 And the article contains the following content:

An environmentally benign route leading to adiponitrile (ADN), a nylon-6,6 intermediate, was achieved by direct vapor-phase nitrilation of di-Me adipate (DMA) with ammonia (NH3) in a fixed-bed reactor. The challenges of this reaction include not only inhibiting both intramol. cyclization and the intermol. polycondensation of the electron-withdrawing group functionalized carbon chain but also suppressing the thermolysis of aliphatic DMA and ADN. Both amphoteric oxides and acidic oxides enable the transformation but exhibit different reactivities. Under evaluation conditions, the acidic oxides exhibit moderate to good nitrile selectivity, while the amphoteric oxides exhibit high DMA conversions with relatively low nitrile selectivity. Under the optimized conditions, the desired ADN was obtained with a selectivity of 84.3% with 97.7% DMA conversion over Nb2O5-1000 consisting of a monoclinic structure/phase (H-Nb2O5). The structure-performance relationship of this catalyst was preliminarily discussed. Furthermore, a tentative reaction pathway consisting of ammonolysis and dehydration processes in a tandem mode was proposed. The experimental process involved the reaction of Methyl 2-cyclopentanonecarboxylate(cas: 10472-24-9).Formula: C7H10O3

The Article related to adiponitrile dimethyl adipate ammonia vapor niobium oxide, Industrial Organic Chemicals, Leather, Fats, and Waxes: Manufacture Of Industrial Organic Chemicals and other aspects.Formula: C7H10O3

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Sako, Makoto; Higashida, Keigo; Kamble, Ganesh Tatya; Kaut, Kevin; Kumar, Ankit; Hirose, Yuka; Zhou, Da-Yang; Suzuki, Takeyuki; Rueping, Magnus; Maegawa, Tomohiro; Takizawa, Shinobu; Sasai, Hiroaki published an article in 2021, the title of the article was Chemo- and enantioselective hetero-coupling of hydroxycarbazoles catalyzed by a chiral vanadium(V) complex.Safety of Methyl 2-cyclopentanonecarboxylate And the article contains the following content:

The catalytic enantioselective oxidative hetero-coupling of arenols using a chiral vanadium(V) complex has been developed. The coupling of hydroxycarbazole derivatives with various arenols provided axially chiral biarenols with high chemo-, regio-, and enantioselectivities. The reaction took place under mild conditions and exhibited satisfactory functional group tolerance. Aerobic oxidative hetero-coupling with β-ketoesters also proceeded with high chemo- and stereoselectivities under slightly modified reaction conditions. The experimental process involved the reaction of Methyl 2-cyclopentanonecarboxylate(cas: 10472-24-9).Safety of Methyl 2-cyclopentanonecarboxylate

The Article related to biarenol preparation enantioselective chemoselective regioselective, hydroxycarbazole arenol oxidative hetero coupling vanadium, Heterocyclic Compounds (One Hetero Atom): Indoles, Indolizines, Carbazoles, and Other Arenopyrroles and other aspects.Safety of Methyl 2-cyclopentanonecarboxylate

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

On October 15, 2021, Wu, Yinrong; Wen, Kangmei; Chen, Jiewen; Shi, Jie; Yao, Xingang; Tang, Xiaodong published an article.Name: Methyl 2-cyclopentanonecarboxylate The title of the article was Copper-Mediated Decarboxylative Coupling between Arylacetic Acids and 1,3-Dicarbonyl Compounds. And the article contained the following:

A copper-mediated decarboxylative coupling reaction between arylacetic acids and 1,3-dicarbonyl compounds was described for the synthesis of ((indolyl)methyl)-oxocycloalkyl-esters, e.g., I. Significantly, methanocycloocta[b]indoles II [R = COOEt, CONHEt, SO2Ph, etc.; R1 = H, 4-Cl, 5-Br, etc.] were also obtained by sequential intramol. dehydrocyclization process in some cases. This protocol featured a broad substrate scope, simple operations, and good yields. Moreover, the products exhibited potent antiproliferative activity against the human cancer cell lines by a MTT assay. The experimental process involved the reaction of Methyl 2-cyclopentanonecarboxylate(cas: 10472-24-9).Name: Methyl 2-cyclopentanonecarboxylate

The Article related to indolyl methyl oxocycloalkyl ester preparation antitumor, arylacetic acid dicarbonyl compound decarboxylative coupling copper mediated, Heterocyclic Compounds (One Hetero Atom): Indoles, Indolizines, Carbazoles, and Other Arenopyrroles and other aspects.Name: Methyl 2-cyclopentanonecarboxylate

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

On October 15, 2021, Hou, Bao-Long; Li, Li-Xuan; Li, Chuang-Chuang published an article.Application In Synthesis of Methyl 2-cyclopentanonecarboxylate The title of the article was Synthesis of the Bridged [5-7-7] Tricyclic Core of Eurifoloid A. And the article contained the following:

We herein describe a new approach for the efficient and asym. construction of the tricyclic core (I) of eurifoloid A, which possesses a unique and highly strained bicyclo[4.4.1] ring system. A rhodium-catalyzed intramol. [3 + 2] dipolar cycloaddition was developed to install synthetically challenging bridged bicyclo[4.3.1] ring systems. The reported chem. shows the feasibility of constructing the eurifoloid A framework using a diastereoselective intramol. [3 + 2] cycloaddition and a ring enlargement. The experimental process involved the reaction of Methyl 2-cyclopentanonecarboxylate(cas: 10472-24-9).Application In Synthesis of Methyl 2-cyclopentanonecarboxylate

The Article related to eurifoloid a bridged tricyclic core preparation, Terpenes and Terpenoids: Diterpenes (C20), Including Gibberellins, Retinoids, Quassinoids, and Tocopherols and other aspects.Application In Synthesis of Methyl 2-cyclopentanonecarboxylate

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

On January 5, 2019, Kumpuga, Bahati Thom; Itsuno, Shinichi published an article.Safety of Methyl 2-cyclopentanonecarboxylate The title of the article was Synthesis of chiral polyurethanes of cinchona alkaloids for the enantioselective synthesis in asymmetric catalysis. And the article contained the following:

Chiral polyurethanes of cinchona alkaloid were synthesized via repetitive Mizoroki-Heck (MH) coupling reaction. The Pd-catalyzed polycondensation of cinchona urethane dimers and aromatic diiodides afforded the chiral polyurethanes. The chiral polyurethane bearing free OH group at the C6′ position of the quinoline ring in the cinchona alkaloid unit showed high catalytic activities and excellent enantioselectivities (up to 97% ee) in the Michael addition reactions. The experimental process involved the reaction of Methyl 2-cyclopentanonecarboxylate(cas: 10472-24-9).Safety of Methyl 2-cyclopentanonecarboxylate

The Article related to chiral polyurethane cinchona alkaloid enantioselective asym catalysis, Chemistry of Synthetic High Polymers: Polymerization Kinetics, Mechanisms, Thermodynamics, Catalysis, Catalysts and other aspects.Safety of Methyl 2-cyclopentanonecarboxylate

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics