Category: 10472-24-9

On April 2, 2021, Liao, Zhehui; Zhang, Jiantao; Cao, Tongxiang; Zhu, Shifa published an article.Quality Control of Methyl 2-cyclopentanonecarboxylate The title of the article was Copper-Catalyzed Asymmetric Synthesis of Bicyclo[3.n.1]alkenones. And the article contained the following:

A series of highly strained bicyclo[3.n.1]alkenones such as I (R = Me, Et, i-Pr) have been successfully constructed in good to excellent enantioselectivities and moderate to good yields by copper-catalyzed formal [3+3] cycloaddition reaction of 2-oxocycloalkanecarboxylates and aryl vinyl ketones or arylethenyl vinyl ketones via nonracemic oxoalkyl-substituted oxocycloalkanecarboxylates such as II (R = Me, Et, i-Pr). The cycloadducts were selectively converted into various valuable bicyclic ring systems holding considerable potential for the construction of natural and bioactive compounds containing a [3.n.1] moiety. The experimental process involved the reaction of Methyl 2-cyclopentanonecarboxylate(cas: 10472-24-9).Quality Control of Methyl 2-cyclopentanonecarboxylate

The Article related to bicycloalkenone enantioselective preparation, copper catalyst enantioselective cycloaddition ketocycloalkanecarboxylate aryl vinyl ketone, enantioselective copper catalyzed michael addition oxocycloalkanecarboxylate vinyl ketone cyclocondensation and other aspects.Quality Control of Methyl 2-cyclopentanonecarboxylate

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

On October 28, 2019, Fan, Lian-Feng; Wang, Tian-Ci; Wang, Pu-Sheng; Gong, Liu-Zhu published an article.SDS of cas: 10472-24-9 The title of the article was Palladium-Catalyzed Asymmetric Allylic C-H Alkylation of 1,4-Dienes with Cyclic β-Keto Esters. And the article contained the following:

In the presence of chiral phosphoramidite ligand, a palladium-catalyzed asym. allylic C-H alkylation of 1,4-dienes with cyclic β-keto esters has been established to afford chiral α,α-disubstituted β-keto esters I (3, R1 = H, Me, F, OMe, Cl, OCH2CH:CH2, OCH2CCMe; R2 = Me, Et, iPr, tBu, PhCH2; R = alkyl, cycloalkyl, Ph, carboxy, carboxamide) in good to excellent yields, with high levels of regioselectivity, E/Z selectivity, and enantioselectivity. 1,4-Dienes bearing a wide scope of functional groups, such as ketone, chloride, ester, and amide as well, have been nicely tolerated. In addition, preliminary application of this method enables a concise formal synthesis of (-)-tanikolide. The experimental process involved the reaction of Methyl 2-cyclopentanonecarboxylate(cas: 10472-24-9).SDS of cas: 10472-24-9

The Article related to asym allylic alkylation keto ester indanone diene palladium catalyst, phosphoramidite palladium chiral allylation catalyst preparation allyl dienyl ketoester, oxo indanecarboxylate cyclopentanecarboxylate asym allylic alkylation palladium phosphoramidite catalyst and other aspects.SDS of cas: 10472-24-9

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Gao, Wen-Chao; Liu, Jianrong; Jiang, Xuefeng published an article in 2021, the title of the article was Phthalimide-based-SSCF3 reagent for enantioselective dithiotrifluoromethylation.Application In Synthesis of Methyl 2-cyclopentanonecarboxylate And the article contains the following content:

An electrophilic phthalimide-based-SSCF3 reagent was designed and prepared for straightforward SSCF3 incorporation of diverse β-keto esters in natural products, pharmaceuticals and biol. mols. The asym. dithiotrifluoromethylation was achieved with a good to excellent enantioselectivity, catalyzed by a cinchona-alkaloid-based catalyst (DHQD)2PHAL via an ammonium-hydrogen-bonded induction mode. The experimental process involved the reaction of Methyl 2-cyclopentanonecarboxylate(cas: 10472-24-9).Application In Synthesis of Methyl 2-cyclopentanonecarboxylate

The Article related to indanone carboxylate dithiotrifluoromethyl phthalimide cinchona catalyst enantioselective dithiotrifluoromethylation, dithiotrifluoromethyl phthalimide indanone carboxylate dmap catalyst dithiotrifluoromethylation, trifluoromethyldisulfanyl indanone carboxylate preparation and other aspects.Application In Synthesis of Methyl 2-cyclopentanonecarboxylate

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

On August 16, 2021, Liu, Xigong; Zhao, Changyin; Zhu, Rongxiu; Liu, Lei published an article.Product Details of 10472-24-9 The title of the article was Construction of Vicinal Quaternary Carbon Stereocenters Through Diastereo- and Enantioselective Oxidative 1,6-Conjugate Addition. And the article contained the following:

The asym. construction of vicinal quaternary carbon stereocenters with at least one moiety in acyclic systems is a formidable challenge. A solution involving diastereo- and enantioselective oxidative 1,6-conjugate addn was disclosed. The practical asym. cross-dehydrogenative coupling of 2,2-diarylacetonitriles and diverse α-substituted cyclic 1,3-dicarbonyls proceeds, for vicinal quaternary carbon stereocenters with one center in acyclic systems, in excellent yields and stereoselectivities. The generality of the approach was further demonstrated by the stereoselective creation of vicinal quaternary carbon stereocenters with both centers in acyclic systems using acyclic β-ketoesters as coupling partners. Computational studies elucidate the origins of both diastereo- and enantioselectivity. The experimental process involved the reaction of Methyl 2-cyclopentanonecarboxylate(cas: 10472-24-9).Product Details of 10472-24-9

The Article related to diarylacetonitrile keto ester copper catalyst enantioselective oxidative conjugate addition, diaryl cyanomethyl alkanone carboxylate preparation, 1,6-conjugate addition, asymmetric catalysis, cross-dehydrogenative coupling, synthetic methods, vicinal quaternary stereocenters and other aspects.Product Details of 10472-24-9

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

On March 15, 2021, Meninno, Sara; Villano, Rosaria; Lattanzi, Alessandra published an article.Name: Methyl 2-cyclopentanonecarboxylate The title of the article was Magnesium Monoperphthalate (MMPP): a Convenient Oxidant for the Direct Rubottom Oxidation of Malonates, β-Keto Esters, and Amides. And the article contained the following:

A mild and convenient protocol for the α-hydroxylation of α-substituted malonates, β-ketoesters, and β-ketoamides is disclosed. Cheap and stable magnesium monoperphthalate (MMPP) was effective for a first direct α-hydroxylation protocol of the Rubottom oxidation, providing tartronic esters, cyclic α-hydroxy β-ketoesters and amides in good to high yields, when working at room temperature and in ethanol as the solvent. The protocol has been successfully scaled up to gram quantity. The experimental process involved the reaction of Methyl 2-cyclopentanonecarboxylate(cas: 10472-24-9).Name: Methyl 2-cyclopentanonecarboxylate

The Article related to malonate magnesium monoperphthalate regioselective rubottom hydroxylation, ketoester magnesium monoperphthalate regioselective rubottom hydroxylation, ketoamide magnesium monoperphthalate regioselective rubottom hydroxylation, hydroxy malonate ketoester ketoamide preparation and other aspects.Name: Methyl 2-cyclopentanonecarboxylate

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

On July 2, 2021, Kabes, Connor; Lucas, Reagan; Gunn, Jack; Gladysz, John published an article.Computed Properties of 10472-24-9 The title of the article was Chiral Cobalt(III) Tris(1,2-diamine) Catalysts That Incorporate Nitrogenous Base Containing Anions for the Bifunctional Activation of Nucleophiles and Electrophiles in Enantioselective Addition Reactions. And the article contained the following:

Here, The lipophilic diastereomeric cobalt complexes Λ or Δ-[Co((S,S)-dpen)3]3+ 2Cl-BArf- (Λ or Δ-(S,S)-23+ 2Cl-BArf-; dpen/BArf- = 1,2-diphenylethylenediamine/B(3,5-C6H3(CF3)2)4-) ,salts of nicotinates, isonicotinates, related sulfonates, and N,N-dimethylaminobenzoate were applied addition reactions. The 6-chloronicotinate salt gaves slower rates and lower ee values, and the 6-aminonicotinate salt gave faster rates and higher ee values. The 6-Me, 2-methoxy, and unsubstituted analogs afforded intermediate results. The 6-aminonicotinate catalyst was applied to additions of di-Me malonate to aryl-substituted nitroolefins and additions of 1,3-dicarbonyl compounds to di-t-Bu azodicarboxylate, with average yields/ee values of 90%/85% and 94%/77%, resp. The authors were unaware of other ionic catalysts for which Bronsted bases was productively incorporated into the anions, which were seldom if ever purposefully functionalized in any manner. The experimental process involved the reaction of Methyl 2-cyclopentanonecarboxylate(cas: 10472-24-9).Computed Properties of 10472-24-9

The Article related to chiral diamine cobalt complex preparation, nitroolefin dimethyl malonate cobalt complex catalyst enantioselective michael addition, ditertiarybutyl azodicarboxylate dicarbonyl compound cobalt catalyst enantioselective michael addition, bistertiarybutoxycarbonyl hydrazino dicarbonyl compound preparation and other aspects.Computed Properties of 10472-24-9

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Yuan, Qianjia; Prater, Matthew B.; Sigman, Matthew S. published an article in 2020, the title of the article was Enantioselective Synthesis of γ-Functionalized Cyclopentenones and β-Functionalized Cycloheptenones Utilizing a Redox-Relay Heck Strategy.Computed Properties of 10472-24-9 And the article contains the following content:

In this report, the desymmetrization of cyclic enones under relay Heck conditions with an array of aryl boronic acids, alkenyl triflates and indole derivatives was described. This method granted facile access to diverse γ-functionalized cyclopentenones I [Ar = Ph, 2-naphthyl, benzo[d][1,3]dioxol-5-yl, 4-oxocyclopent-2-en-1-yl, etc.] and δ-functionalized cycloheptenones II [R = Ph, 4-CF3C6H4, C(Me):C(Me)CO2Et, etc.]. Using this approach, a formal synthesis of (S)-baclofen was completed in high yield and excellent enantioselectivity. The experimental process involved the reaction of Methyl 2-cyclopentanonecarboxylate(cas: 10472-24-9).Computed Properties of 10472-24-9

The Article related to gamma functionalized cyclopentenone enantioselective preparation, cyclopentenone aryl boronic acid alkenyl triflate palladium relay heck, delta functionalized cycloheptenone enantioselective preparation, cycloheptenone aryl boronic acid alkenyl triflate palladium relay heck, asymmetric catalysis, c–c coupling, heck reaction, palladium and other aspects.Computed Properties of 10472-24-9

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Wu, Binyu; Wen, Xiaolu; Chen, Hongbing; Hu, Lin published an article in 2021, the title of the article was N-Nosyl-O-bromoethyl hydroxylamine acts as a multifunctional formaldehyde, formaldimine, and 1,2-oxazetidine surrogate for C-C and C-O bond-forming reactions.Application of 10472-24-9 And the article contains the following content:

N-Nosyl-O-bromoethyl hydroxylamine, a bench stable solid, could function as a novel formaldehyde, formaldimine and 1,2-oxazetidine surrogate under DBU basic conditions were described. By merely using this simple reagent, a broad range of synthetically useful β-aminomethyl ketones I [R1 = Me, Ph, 2-furyl, etc.; R2 = Me, Et, allyl, Bn; R1R2 = (CH2)3, (CH2)4, (CH2)5, etc.; R3 = Ac, CO2Me, CO2Et, SO2Ph] and α-hydroxymethyl ketones II [R4 = Me, Et, allyl, Bn; Q = (CH2)n, n = 1,2], as well as chiral α-alkoxyl indanone carboxylates III [R5 = H, 4-MeO, 5-F, etc.; X = OCH2CH2] and α-aminomethyl indanone carboxylates III [X = CH2] could be divergently obtained via chemo- and stereoselective aldol, Mannich or umpolung C-O bond-forming reactions. The challenging catalytic asym. Mannich reaction of formaldimine equivalent was also realized with moderate enantioselectivities. The experimental process involved the reaction of Methyl 2-cyclopentanonecarboxylate(cas: 10472-24-9).Application of 10472-24-9

The Article related to aminomethyl ketone preparation, nosyl bromoethyl hydroxylamine benzoyl acetate bond formation, hydroxymethyl ketone preparation, hydroxy ketone nosyl bromoethyl hydroxylamine bond formation, carboxylate indanone hydroxymethyl preparation enantioselective chemoselective, alkoxyl indanone carboxylate preparation enantioselective chemoselective and other aspects.Application of 10472-24-9

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

On April 27, 2020, Shaikh, Aslam C.; Veleta, Jose M.; Bloch, Jan; Goodman, Hannah J.; Gianetti, Thomas L. published an article.Name: Methyl 2-cyclopentanonecarboxylate The title of the article was Syntheses of Phosphonium Salts from Phosphines and Carbenium: Efficient CO2 Fixation and Phase-Transfer Catalysts. And the article contained the following:

A new library of phosphonium salts was synthesized from the reaction of tris-(2,6-dimethoxyphenyl)carbenium with different phosphines. The resultant phosphonium salts work as efficient phase-transfer catalysts for the alkylation of 1,3-dicarbonyl compounds One compound, a bifunctional phosphonium salt prepared from tris-(2,6-dimethoxyphenyl)carbenium and an aminophosphine, also is an efficient catalyst for CO2 fixation reactions with epoxides under mild conditions. The experimental process involved the reaction of Methyl 2-cyclopentanonecarboxylate(cas: 10472-24-9).Name: Methyl 2-cyclopentanonecarboxylate

The Article related to carbeniumphosphonium salt preparation phase transfer catalyst carbon dioxide fixation, phenylcarbenium reaction phosphine, phosphonium carbenium salt preparation catalyst epoxide carbon dioxide fixation, cyclic carbonate preparation, alkylation keto ester carbeniumphosphonium salt phase transfer catalyst, crystal structure triphenylcarbenium phosphonium salt and other aspects.Name: Methyl 2-cyclopentanonecarboxylate

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

On September 17, 2021, Zhu, Yasheng; Wang, Hongliang; Wang, Gang; Wang, Zehua; Liu, Zhaopeng; Liu, Lei published an article.Related Products of 10472-24-9 The title of the article was Enantioselective Construction of Single and Vicinal All-Carbon Quaternary Stereocenters through Ion Pair Catalyzed 1,6-Conjugate Addition. And the article contained the following:

An asym. 1,6-conjugate addition to presynthesized δ-aryl-δ-cyano disubstituted para-quinone methides I (R = H, 3-Me, 3-bromo; Ar = Ph, 4-methylphenyl, 2-naphthyl, etc.) through bifunctional phosphonium-amide promoted ion pair catalysis for acyclic all-carbon quaternary stereocenter construction has been described. Both acyclic and cyclic 1,3-dicarbonyls CH2(C(O)OR1)2 (R1 = Ph, 2-methylphenyl, benzyl, etc.)/II (R2 = Me, Et, Bu, allyl) participate in asym. alkylation reaction, furnishing a wide array of diarylmethanes bearing a single acyclic or vicinal cyclic and acyclic quaternary carbon stereocenters III/IV in high efficiency with excellent stereoselectivity. Computational studies elucidate the origin of enantioselectivity. The experimental process involved the reaction of Methyl 2-cyclopentanonecarboxylate(cas: 10472-24-9).Related Products of 10472-24-9

The Article related to cyano hydroxyphenyl aryl methyl propane dicarboxylic ester preparation enantioselective, quinonemethide acyclic dicarbonyl compound conjugate addition phosphonium amide catalyst, cyanohydroxyphenyl aryl methyl oxocyclopentane carboxylic ester preparation enantioselective, cyclic dicarbonyl compound quinonemethide conjugate addition phosphonium amide catalyst and other aspects.Related Products of 10472-24-9

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics