Jian, Tongtong published the artcileMetabolomic comparison between natural Huaier and artificial cultured Huaier, SDS of cas: 103-26-4, the publication is Biomedical Chromatography (2022), 36(6), e5355, database is CAplus and MEDLINE.
Vanderbylia robiniophila (Murrill) B. K. (Huaier) is a kind of higher fungal fruiting body that is parasitic on the trunk of Sophora japonica and Robinia pseudoacacia L.. As a traditional Chinese medicine with a history of more than 1,600 years, Huaier has attracted wide attention for its excellent anticancer activity. A systematic study on the metabolome differences between natural Huaier and artificial cultured Huaier was conducted using liquid chromatog.-mass spectrometry in this study. Principal component anal. and orthogonal projection on latent structure-discriminant anal. results showed that cultured Huaier evidently separated and individually separated from natural Huaier, indicating metabolome differences between natural and cultured Huaier. Hierarchical clustering anal. was further performed to cluster the differential metabolites and samples based on their metabolic similarity. The higher contents of amino acids, alkaloids and terpenoids in natural Huaier make it an excellent choice as a traditional Chinese medicine for anticancer or nutritional supplementation. The results of the Bel-7,402 and A549 cell cytotoxicity tests showed that the anticancer activity of natural Huaier was better than that of cultured Huaier. This may be due to the difference in chem. composition, which makes the anticancer activities of natural and cultured Huaier different.
Biomedical Chromatography published new progress about 103-26-4. 103-26-4 belongs to esters-buliding-blocks, auxiliary class Alkenyl,Benzene,Ester,Protease,Tyrosinase,Natural product, name is Methyl 3-phenyl-2-propenoate, and the molecular formula is C10H10O2, SDS of cas: 103-26-4.
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