Category: 10203-58-4

Tsuji, Hiroaki et al. published their research in Tetrahedron Letters in 2021 | CAS: 10203-58-4

Diethyl isobutylmalonate (cas: 10203-58-4) belongs to esters. Esters are also usually derived from carboxylic acids. It may also be obtained by reaction of acid anhydride or acid halides with alcohols or by the reaction of salts of carboxylic acids with alkyl halides. Esters contain a carbonyl center, which gives rise to 120° C–C–O and O–C–O angles. Unlike amides, esters are structurally flexible functional groups because rotation about the C–O–C bonds has a low barrier. Their flexibility and low polarity is manifested in their physical properties; they tend to be less rigid (lower melting point) and more volatile (lower boiling point) than the corresponding amides. Electric Literature of C11H20O4

Nickel-catalyzed hydroalkylation of 1,3-dienes with malonates using a homoallyl carbonate as the 1,3-diene and hydride source was written by Tsuji, Hiroaki;Takahashi, Yoshiyuki;Kawatsura, Motoi. And the article was included in Tetrahedron Letters in 2021.Electric Literature of C11H20O4 This article mentions the following:

The nickel-catalyzed hydroalkylation of 1,3-dienes with malonates using homoallyl carbonates RCH(OCOOCH3)CH2CH=CH2 (R = 4-chlorophenyl, piperonyl, cyclohexyl, etc.) as the 1,3-diene and hydride source was reported. A broad range of homoally carbonates and malonate derivatives R1CH(COOR2)2 (R1 = H, Ph, Me, i-Bu, etc.; R2 = Et, i-Pr, Me, Bn, t-Bu) was well tolerated under a Ni/DPEphos catalyst system, providing the corresponding 1,2-hydroalkylation products RCH=CH2CH(CH3)CH((COOCH3)2)CH3 in 40-94% yields with excellent regioselectivity. Also, suggested the possible reaction mechanism for the nickel-catalyzed hydroalkylation of in situ generated 1,3-dienes with malonates is suggested. In the experiment, the researchers used many compounds, for example, Diethyl isobutylmalonate (cas: 10203-58-4Electric Literature of C11H20O4).

Diethyl isobutylmalonate (cas: 10203-58-4) belongs to esters. Esters are also usually derived from carboxylic acids. It may also be obtained by reaction of acid anhydride or acid halides with alcohols or by the reaction of salts of carboxylic acids with alkyl halides. Esters contain a carbonyl center, which gives rise to 120° C–C–O and O–C–O angles. Unlike amides, esters are structurally flexible functional groups because rotation about the C–O–C bonds has a low barrier. Their flexibility and low polarity is manifested in their physical properties; they tend to be less rigid (lower melting point) and more volatile (lower boiling point) than the corresponding amides. Electric Literature of C11H20O4

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Abe, Kyuji et al. published their research in Tanabe Seiyaku Kenkyu Nenpo in 1957 | CAS: 10203-58-4

Diethyl isobutylmalonate (cas: 10203-58-4) belongs to esters. Esters are widespread in nature and are widely used in industry. In nature, fats are in general triesters derived from glycerol and fatty acids. Esters are responsible for the aroma of many fruits. Many esters have the potential for conformational isomerism, but they tend to adopt an s-cis (or Z) conformation rather than the s-trans (or E) alternative, due to a combination of hyperconjugation and dipole minimization effects. The preference for the Z conformation is influenced by the nature of the substituents and solvent, if present. Lactones with small rings are restricted to the s-trans (i.e. E) conformation due to their cyclic structure.Related Products of 10203-58-4

Intravenous anesthetics of thiobarbital series. VI. Synthesis of sodium 5-allyl-5-isobutyl-2-thiobarbiturate was written by Abe, Kyuji;Matsui, Kazuo. And the article was included in Tanabe Seiyaku Kenkyu Nenpo in 1957.Related Products of 10203-58-4 This article mentions the following:

Na (11.5 g.) in 200 cc. EtOH is warmed with 80 g. CH2(CO2Et)2 at 40-50°, and the mixture treated with 102 g. iso-BuI over 4 hrs. to afford 74.5 g. di-Et isobutylmalonate (I), b7 95-8°. I (45 g.), 4.8 g. Na, and 150 cc. EtOH is warmed to 40-50°, 24.8 g. allyl bromide added over 1 hr., and the mixture boiled 3 hrs. to afford 45.6 g. di-Et isobutylallylmalonate (II), b7 114-16°. Isobutylation of di-Et allylmalonate also affords II in 81.9% yield. NCCH2CO2Et (57 g.) in a mixture of 11.5 g. Na and 300 cc. alc. treated with 102 g. iso-BuI affords 46.7 g. Et isobutylcyanoacetate (III), b9 93-7°. α-Chloroisocaproic acid (15 g.) in 50 cc. H2O is neutralized by NaHCO3, heated with 13 g. KCN, evaporated to dryness, a mixture of 26 cc. alc. and 20 cc. concentrated H2SO4 added, and the solution boiled 4 hrs. and distilled in vacuo to afford 7.5 g. III. III (42 g.), 5.7 g. Na, and 200 cc. EtOH is treated with 31 g. allyl bromide to afford 41.6 g. Et isobutylallylcyanoacetate (IV), b10 114-16°. IV (41.6 g.) and 30 g. thiourea in a mixture of 9.2 g. Na and 150 cc. EtOH boiled 6 hrs. and worked up gave 5-isobutyl-5-allyl-4-imino-2-thiobarbiturate (V), yellow, m. 276-8° (dioxane). V is boiled with 150 g. 30% H2SO4 to yield 24 g. 5-isobutyl-5-allyl-2-thiobarbiturate (VI), leaves, m. 145-7° (benzene). II (185 g.) and 110 g. thiourea boiled 7 hrs. with a mixture of 33.2 g. Na and 700 cc. MeOH yield VI. VI Na salt, a light yellow powder, is very hygroscopic and soluble in H2O, and useful as an ultra-short-acting intravenous anesthetic. In the experiment, the researchers used many compounds, for example, Diethyl isobutylmalonate (cas: 10203-58-4Related Products of 10203-58-4).

Diethyl isobutylmalonate (cas: 10203-58-4) belongs to esters. Esters are widespread in nature and are widely used in industry. In nature, fats are in general triesters derived from glycerol and fatty acids. Esters are responsible for the aroma of many fruits. Many esters have the potential for conformational isomerism, but they tend to adopt an s-cis (or Z) conformation rather than the s-trans (or E) alternative, due to a combination of hyperconjugation and dipole minimization effects. The preference for the Z conformation is influenced by the nature of the substituents and solvent, if present. Lactones with small rings are restricted to the s-trans (i.e. E) conformation due to their cyclic structure.Related Products of 10203-58-4

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Tsuji, Hiroaki et al. published their research in Tetrahedron Letters in 2021 | CAS: 10203-58-4

Diethyl isobutylmalonate (cas: 10203-58-4) belongs to esters. Esters perform as high-grade solvents for a broad array of plastics, plasticizers, resins, and lacquers, and are one of the largest classes of synthetic lubricants on the commercial market. Liquid esters of low volatility serve as softening agents for resins and plastics. Esters also include many industrially important polymers. Polymethyl methacrylate is a glass substitute sold under the names Lucite and Plexiglas; polyethylene terephthalate is used as a film (Mylar) and as textile fibres sold as Terylene, Fortrel, and Dacron.Name: Diethyl isobutylmalonate

Ruthenium-catalyzed stereospecific benzylic alkylation of optically active benzyl esters with malonate nucleophiles was written by Tsuji, Hiroaki;Suzuki, Koki;Kawatsura, Motoi. And the article was included in Tetrahedron Letters in 2021.Name: Diethyl isobutylmalonate This article mentions the following:

Herein, the study for the ruthenium-catalyzed benzylic alkylation of chiral benzyl esters with malonates as a carbon nucleophile was described. A combination of [Cp*RuCl2]2 and picolinic acid found to be effective for the title reaction, provided the chiral benzylic alkylation products with retention of stereochem. of the starting material. The ruthenium catalysis was proceed via a double inversion mechanism was proposed. In the experiment, the researchers used many compounds, for example, Diethyl isobutylmalonate (cas: 10203-58-4Name: Diethyl isobutylmalonate).

Diethyl isobutylmalonate (cas: 10203-58-4) belongs to esters. Esters perform as high-grade solvents for a broad array of plastics, plasticizers, resins, and lacquers, and are one of the largest classes of synthetic lubricants on the commercial market. Liquid esters of low volatility serve as softening agents for resins and plastics. Esters also include many industrially important polymers. Polymethyl methacrylate is a glass substitute sold under the names Lucite and Plexiglas; polyethylene terephthalate is used as a film (Mylar) and as textile fibres sold as Terylene, Fortrel, and Dacron.Name: Diethyl isobutylmalonate

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Schulz, Elisabeth et al. published their research in Pharmazie in 1983 | CAS: 10203-58-4

Diethyl isobutylmalonate (cas: 10203-58-4) belongs to esters. Esters perform as high-grade solvents for a broad array of plastics, plasticizers, resins, and lacquers, and are one of the largest classes of synthetic lubricants on the commercial market. Polyesters are important plastics, with monomers linked by ester moieties. Esters contain a carbonyl center, which gives rise to 120° C–C–O and O–C–O angles. Unlike amides, esters are structurally flexible functional groups because rotation about the C–O–C bonds has a low barrier. Their flexibility and low polarity is manifested in their physical properties; they tend to be less rigid (lower melting point) and more volatile (lower boiling point) than the corresponding amides. HPLC of Formula: 10203-58-4

Synthesis and some pharmacological properties of alkyl esters of various ω-phenyl DL-amino acids was written by Schulz, Elisabeth;Sprung, W. D.;Kroening, G.. And the article was included in Pharmazie in 1983.HPLC of Formula: 10203-58-4 This article mentions the following:

DL-Ph(CH2)mCH(NH2)(CH2)nCO2R.HCl (I; m = 0, n = 0, 1, 2; m = 2, n = 0; R = straight- or branched-chain alkyl) (28 compounds) were prepared by esterification of the corresponding acids. Spasmolytic activities were determined in vitro and found to correlate with the length of the carbon chain in the mol. In the experiment, the researchers used many compounds, for example, Diethyl isobutylmalonate (cas: 10203-58-4HPLC of Formula: 10203-58-4).

Diethyl isobutylmalonate (cas: 10203-58-4) belongs to esters. Esters perform as high-grade solvents for a broad array of plastics, plasticizers, resins, and lacquers, and are one of the largest classes of synthetic lubricants on the commercial market. Polyesters are important plastics, with monomers linked by ester moieties. Esters contain a carbonyl center, which gives rise to 120° C–C–O and O–C–O angles. Unlike amides, esters are structurally flexible functional groups because rotation about the C–O–C bonds has a low barrier. Their flexibility and low polarity is manifested in their physical properties; they tend to be less rigid (lower melting point) and more volatile (lower boiling point) than the corresponding amides. HPLC of Formula: 10203-58-4

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

9/6/21 News The origin of a common compound about 10203-58-4

The synthetic route of 10203-58-4 has been constantly updated, and we look forward to future research findings.

Reference of 10203-58-4,Some common heterocyclic compound, 10203-58-4, name is Diethyl isobutylmalonate, molecular formula is C11H20O4, traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc, below Introduce a new synthetic route.

Example 724: 2-(2-cyclopropylmethoxy-5-fluoro-4′-trifluoromethyl-biphenyl-4-yl)-4- methyl-pentanoic acid. Step lDiethyl 2-(2,5-difluoro-4-nitrophenyl)-2-isobutylmalonate2-Isobutylmalonic acid diethyl ester (40.Og, 0.185 mol) in DMF (5OmL) was added dropwise to a stirred suspension of sodium hydride (60% in mineral oil, 8.0g, 0.33 mol) in 200 mL DMF (20OmL) over 20 min. at O0C under nitrogen. The mixture was stirred for 0.5 h at room temperature, cooled to 0 C and l,2,4-trifluoro-5-nitro-benzene (30.0g, 169.5 mmol) in DMF (15OmL) was added dropwise. The resulting reaction mixture was stirred at room temperature for 16h, poured into ice water (20OmL) and extracted with EtOAc (3x10OmL). The combined organic phases were washed with water (3x10OmL), brine (10OmL) and dried (MgStheta4). Evaporation of solvent under reduced pressure gave a brown oil which was purified by column chromatography over silica gel (Heptane-EtOAc, gradient) to give 57.0 g (90%) of 2-(2,5- difluoro-4-nitrophenyl)-2-isobutylmalonic acid diethyl ester as yellow oil. H NMR (300 MHz, CDCVTMS): delta 7.87 (dd, J = 12.3, 6.0 Hz, IH), 7.79 (dd, J = 10.1, 6.4 Hz, IH), 4.30^1.18 (m, 4H), 2.27 (d, J = 5.8 Hz, 2H), 1.60-1.50 (m, IH), 1.26 (t, J = 7.1 Hz, 6H), 0.82 (d, J = 7.0 Hz, 6H); 13C NMR (75 MHz, CDCI3/TMS): delta 168.2, 155.1 (d, 1JcF = 252.3 Hz), 150.9 (d, 1JcF = 263.2 Hz), 135.7, 135.1, 120.0 (dd, 2JCF = 26.0, 3JCF = 4.0 Hz), 113.0 (d, 2JCF = 29.0 Hz), 62.3, 43.1, 24.9, 23.8, 13.8.

The synthetic route of 10203-58-4 has been constantly updated, and we look forward to future research findings.

Reference:
Patent; ENVIVO PHARMACEUTICALS, INC.; WO2009/86277; (2009); A1;,
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

1-Sep-21 News Analyzing the synthesis route of 10203-58-4

Statistics shows that Diethyl isobutylmalonate is playing an increasingly important role. we look forward to future research findings about 10203-58-4.

Electric Literature of 10203-58-4, These common heterocyclic compound, 10203-58-4, name is Diethyl isobutylmalonate, its traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc, below Introduce a new synthetic route.

2-lsobuty3malonic acid diethyl ester (40. Og, 0.185 rnol) in DMF (50mL) was added dropwise to a stirred suspension of sodium hydride (60% in mineral oil, 8.0g, 0.33 mol) in 200 mL DMF (200mL) over 20 rain, at 0C under nitrogen. The mixture was stirred for 0.5 h at room temperature, cooled to 0 C and l,2,4-trifluoro-5-nitro-benzene (30. Og, 169.5 mmol) in DMF (150mL) was added dropwise. The resulting reaction mixture was stirred at room temperature for 16b, poured into ice water (2 OOmL) and extracted with EtOAc (3×1 OOmL). The combined organic phases were washed with water (3×1 OOmL), brine (lOOmL) and dried (MgS04).Evaporation of solvent under reduced pressure ga ve a brown oil which was purified by column chromatography over silica gel (Fle tane-EtOAc, gradient) to give 57.0 g (90%) of 2-(2,5- difluoro-4-nitropheny3)-2-isobuty3malonic acid diethyl ester as yellow oil.3FI NMR (300 MHz,CDCI3/TMS): delta 7.87 (dd, J = 12.3, 6.0 Flz, 1H), 7.79 (dd, J = 10.1 , 6.4 Hz, 1 H), 4.30-4.18 (m, 4H), 2.27 (d, J = 5.8 Hz, 2H), 1.60-1.50 (m, i l l ). 1.26 (t, J = 7.1 Hz, 6H), 0.82 (d, J = 7.0 Hz, 6H);3C NMR (75 MHz, CDClv’TMS): delta 168.2, 155.1 (d, Ja= 252.3 Hz), 150.9 (d, CF = 263.2 Hz), 135.7, 135. L 120.0 (dd,2JCF= 26.0,1= 4.0 Hz), 113.0 (d,2JC¥= 29.0 Hz), 62.3, 43.1 , 24.9, 23.8, 13.8.

Statistics shows that Diethyl isobutylmalonate is playing an increasingly important role. we look forward to future research findings about 10203-58-4.

Reference:
Patent; ENVIVO PHARMACEUTICALS, INC.; KOENIG, Gerhard; BLAIN, Jean-francois; WO2013/106328; (2013); A1;,
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

New downstream synthetic route of C11H20O4

These compound has a wide range of applications. It is believed that with the continuous development of the source of the synthetic route Diethyl isobutylmalonate, its application will become more common.

Application of 10203-58-4,Some common heterocyclic compound, 10203-58-4, name is Diethyl isobutylmalonate, molecular formula is C11H20O4, traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc, below Introduce a new synthetic route.

General procedure: To a stirred suspension of LiAlH4 (3.5 equiv.) in dry THF (1.0mL/mmol) under nitrogen atmosphere was slowly added a solution of the corresponding diethyl alkylpropanedioate (1 equiv.) in dry THF (1.0mL/mmol) at 0C. The reaction mixture was allowed to warm to rt and was then refluxed for 48h before being cooled to 0C. The reaction was quenched by careful addition of a saturated aqueous solution of NH4Cl until neutral or acidic pH. The precipitated aluminium salts were removed by filtration through a pad of Celite and washed with diethylether or a mixture of MeOH/CH2Cl2/Et2O 1:1:1. The organic phase of the filtrate was recovered, washed with water and brine, dried over MgSO4, filtered off and concentrated under reduced pressure to afford the corresponding crude product which was pure enough to be directly used in the next step.

These compound has a wide range of applications. It is believed that with the continuous development of the source of the synthetic route Diethyl isobutylmalonate, its application will become more common.

Reference:
Article; Meguellati, Amel; Ahmed-Belkacem, Abdelhakim; Nurisso, Alessandra; Yi, Wei; Brillet, Rozenn; Berqouch, Nawel; Chavoutier, Laura; Fortune, Antoine; Pawlotsky, Jean-Michel; Boumendjel, Ahcene; Peuchmaur, Marine; European Journal of Medicinal Chemistry; vol. 115; (2016); p. 217 – 229;,
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Analyzing the synthesis route of 10203-58-4

These compound has a wide range of applications. It is believed that with the continuous development of the source of the synthetic route Diethyl isobutylmalonate, its application will become more common.

Electric Literature of 10203-58-4,Some common heterocyclic compound, 10203-58-4, name is Diethyl isobutylmalonate, molecular formula is C11H20O4, traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc, below Introduce a new synthetic route.

To a solution of diethyl isobutylmalonate (50.0 g, 231 mmol) in anhydrous DMF (200 mL) cooled in an ice bath was added aH (60 %, 1 1.1 g, 277 mmol) in small portions. After the addition, the reaction mixture was stirred at 0C for 10 min and then at room temperature for 30 min. 5-Chloro-2-nirrobenzotrifluoride (47.3 g, 210 mmol) in anhydrous DMF (50 mL) was added dropwise and the mixture was stirred at room temperature for two days. The DMF was removed under high vacuum and the residue was diluted with ethyl acetate (400 mL). Water (400 mL) was added dropwise; ammonium chloride (25 g) was added and the layers were separated. The organic layer was washed with brine (400 mL), dried over sodium sulfate, and concentrated under reduced pressure to give a red-brown oil, which was purified by silica-gel flashchromatography eluting with heptane / ethyl acetate (12: 1) to give the desired product diethyl 2-isobutyl-2-(4-nilro-3-(trifiuoromethyl)phenyl)malonate (74.4 g, 87%) as a yellow oil:]H NMR (300 MHz, CDC13): delta 8.07 (s, 1 H), 7.94 (d, 2 H, J ——- 8.7 Hz), 7.88 (d, 2 I S . ./ 8.7 Hz), 4.25 (m, 4 H), 2.33 (d, 2 H, J= 6.6 Hz), 1.51 (m, 1 H), 1.26 (t, 6 H, J = 7.2 Hz), 0.84 (d, 6 H, J = 6.6 Hz);J 3C MR (75 MHz, CDC13): delta 169.23, 146.71 , 142.86, 132.94, 127.94 (q, J —— 5 Hz), 124.55, 123.12 (q, J —— 33 Hz), 121 .79 (q, J = 272Hz), 62.19, 65.59, 44.16, 24.66, 23.66, 13.89.

These compound has a wide range of applications. It is believed that with the continuous development of the source of the synthetic route Diethyl isobutylmalonate, its application will become more common.

Reference:
Patent; ENVIVO PHARMACEUTICALS, INC.; KOENIG, Gerhard; BLAIN, Jean-francois; WO2013/106328; (2013); A1;,
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

New downstream synthetic route of 10203-58-4

Chemical properties determine the actual use. Each compound has specific chemical properties and uses. We look forward to more synthetic routes in the future to expand reaction routes of 10203-58-4.

Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 10203-58-4, name is Diethyl isobutylmalonate, This compound has unique chemical properties. The synthetic route is as follows., Recommanded Product: 10203-58-4

EXAMPLE 2 Preparation of 2-ethoxycarbonyl-4-methylvaleric acid A mixture of potassium hydroxide at 85% (3.6 g; 57.34 moles), water (10 ml) and ethanol (10 ml) was heated at 70 C. and hence ethyl 2-ethoxycarbonyl-4-methylvalerate (11.75 g; 54.34 mmoles), prepared as described in example 1, was therein added. After keeping the reaction mixture at reflux temperature for 2 hours, ethanol was evaporated and the resultant solution was washed with ethyl acetate and acidified with concentrated hydrochloric acid. After extracting with ethyl acetate, drying and evaporating the solvent at reduced pressure, 2-ethoxycarbonyl-4-methylvaleric acid (6.7 g; 65.5% yield) was obtained as a colorless oil. 1 H-NMR (200 MHz, CDCl3): delta (ppm): 0.90 (d, 6H); 1.25 (t, 3H); 1.60 (m, 1H); 1.79 (t, 2H); 3.44 (t, 1H); 4.19 (g, 2H).

Chemical properties determine the actual use. Each compound has specific chemical properties and uses. We look forward to more synthetic routes in the future to expand reaction routes of 10203-58-4.

Reference:
Patent; Zambon Group S.p.A.; US5739123; (1998); A;,
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Sources of common compounds: 10203-58-4

Synthetic Route of 10203-58-4,Some common heterocyclic compound, 10203-58-4, name is Diethyl isobutylmalonate, molecular formula is C11H20O4, traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc, below Introduce a new synthetic route.

Synthetic Route of 10203-58-4,Some common heterocyclic compound, 10203-58-4, name is Diethyl isobutylmalonate, molecular formula is C11H20O4, traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc, below Introduce a new synthetic route.

B. OCP-CO-CH(Bui)-CO2 Et Ethyl 2-(ethoxycarbonyl)-4-(methyl)pentanoate (6 g., 28 mM) was dissolved in ethanol (9 ml.) and 4 N-aqueous sodium hydroxide (7 ml.) was added. The mixture was stirred at ambient temperature for 1 hour and then evaporated. The residue was diluted with water (30 ml.) and the aqueous solution was washed with diethyl ether (3*10 ml.). The combined ethereal washings were backextracted with water (5 ml.). The combined aqueous phases were acidified to pH 3 at 0 C. with citric acid, and the resulting oil was extracted into ethyl acetate (4*20 ml.). The combined extracts were washed with water (2*20 ml.) and dried (MgSO4). The mixture was filtered and the solvent was evaporated to give 2-ethoxycarbonyl-4-methylpentanoic acid as an oil.

These compound has a wide range of applications. It is believed that with the continuous development of the source of the synthetic route Diethyl isobutylmalonate, its application will become more common.

Reference:
Patent; Imperial Chemical Industries PLC; US4421744; (1983); A;,
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics