Toshima, Hiroaki; Saito, Masatoshi; Yoshihara, Teruhiko published the artcile< Total synthesis of (+)-(2S,3R)-Piscidic acid via catalytic asymmetric dihydroxylation of a trisubstituted olefin>, Safety of (9Z,12Z)-Methyl octadeca-9,12-dienoate, the main research area is catalysis asym dihydroxylation trisubstituted olefin; piscidic acid total synthesis; asymmetric dihydroxylation; catalytic asymmetric synthesis; piscidic acid.
(+)-(2S,3R)-Piscidic acid was efficiently synthesized with high optical purity (90% e.e.) via Sharpless catalytic asym. dihydroxylation of a trisubstituted olefin in only 6 steps from com. available 4-hydroxyphenyl-pyruvic acid as the starting material. The reaction proceeded with high optical purity by using the chiral ligands, dihydroquinidine 2,5-diphenyl-4,6-pyrimidinediyl diether or dihydroquinidine 1,4-anthraquinonediyl diether.
Bioscience, Biotechnology, and Biochemistry published new progress about Dihydroxylation (stereoselective). 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, Safety of (9Z,12Z)-Methyl octadeca-9,12-dienoate.
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics