Yuan, Feipeng; Hou, Zhen-Lin; Pramanick, Pranab K.; Yao, Bo published the artcile< Site-selective modification of α-amino acids and oligopeptides via native amine-directed γ-C(sp3)-H arylation>, Application of C8H18ClNO2, the main research area is amino acid functionalization arylation aryl iodide amine directed acylation; peptide coupling functionalization arylation aryl iodide amine solvent effect.
Site-selective modification of chem. and biol. valuable α-amino acids and peptides is of great importance for biochem. study and pharmaceutical development. Few methods based on remote C(sp3)-H functionalization of aliphatic side-chains of peptides has been disclosed in recent years. In this report, we developed a novel approach for γ-C(sp3)-H and γ-/δ-C(sp2)-H arylation of α-amino acids with α-hydrogen by native amine-directed C-H functionalization and further realized the γ-C(sp3)-H arylation of N-terminally unprotected peptides.
Organic Letters published new progress about Acylation. 2743-40-0 belongs to class esters-buliding-blocks, and the molecular formula is C8H18ClNO2, Application of C8H18ClNO2.
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics