Enders, Dieter; Henseler, Alexander published the artcile< A Direct Intermolecular Cross-Benzoin Type Reaction: N-Heterocyclic Carbene-Catalyzed Coupling of Aromatic Aldehydes with Trifluoromethyl Ketones>, Reference of 112-63-0, the main research area is aldehyde aromatic coupling ketone trifluoromethyl benzoin heterocyclic carbene coupling.
A direct intermol. cross-benzoin-type condensation catalyzed by an N-heterocyclic carbene has been developed. The cross-coupling of com. available aromatic aldehydes R1CHO (R1 = Ph, 4-ClC6H4, 4-MeC6H4, etc.) and trifluoromethyl ketones R2COCF3 (R2 = Ph, 4-ClC6H4, 4-FC6H4) gave α-hydroxy-α-trifluoromethyl ketones R1C(O)C(OH)(CF3)R2 bearing a quaternary stereocenter with excellent chemoselectivity and good to excellent yields.
Advanced Synthesis & Catalysis published new progress about Aryl aldehydes Role: RCT (Reactant), RACT (Reactant or Reagent). 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, Reference of 112-63-0.
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics