Perkins, M. John et al. published new progress in experiments with the help of cas: 3779-29-1

Diethyl cyclobutane-1,1-dicarboxylate (cas:3779-29-1
) is a solid catalyst that can be used in the synthesis of alkylating agents. It is used in the manufacture of cyclopropyl ketones and has been shown to exhibit anticancer properties.

COA of Formula: C10H16O4In 1985, Perkins, M. John;Adae-Amoakoh, Sylvia;Mitchell, John C.;Smith, Brian V. published 《Intramolecular cyclizations of primary alkyl esters of 3-bromopropylmalonic acid: an unexpected correlation between activation parameters and alkyl chain lengths》. 《Journal of Chemical Research, Synopses》published the findings. The article contains the following contents:

The cyclization rate of Br(CH2)3CH(CO2R)2 [R = Me, Et, Bu, (CH2)5Me] increased regularly with the chain length of R. Plots of the entropy and enthalpy of activation of the reaction vs. the chain length unexpectedly gave linear graphs of high correlation coefficient (0.98 and 0.99, resp.).Diethyl cyclobutane-1,1-dicarboxylate (cas: 3779-29-1) were involved in the experimental procedure.

Diethyl cyclobutane-1,1-dicarboxylate (cas:3779-29-1
) is a solid catalyst that can be used in the synthesis of alkylating agents. It is used in the manufacture of cyclopropyl ketones and has been shown to exhibit anticancer properties.

Reference:
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