Glycerides are fatty acid esters of glycerol; they are important in biology, being one of the main classes of lipids and comprising the bulk of animal fats and vegetable oils. 2495-37-6, formula is C11H12O2, Name is Benzyl methacrylate. Esters typically have a pleasant smell; those of low molecular weight are commonly used as fragrances and are found in essential oils and pheromones. Recommanded Product: Benzyl methacrylate.
Burroughs, Laurence;Amer, Mahetab H.;Vassey, Matthew;Koch, Britta;Figueredo, Grazziela P.;Mukonoweshuro, Blessing;Mikulskis, Paulius;Vasilevich, Aliaksei;Vermeulen, Steven;Dryden, Ian L.;Winkler, David A.;Ghaemmaghami, Amir M.;Rose, Felicity R. A. J.;de Boer, Jan;Alexander, Morgan R. research published 《 Discovery of synergistic material-topography combinations to achieve immunomodulatory osteoinductive biomaterials using a novel in vitro screening method: The ChemoTopoChip》, the research content is summarized as follows. Human mesenchymal stem cells (hMSCs) are widely represented in regenerative medicine clin. strategies due to their compatibility with autologous implantation. Effective bone regeneration involves crosstalk between macrophages and hMSCs, with macrophages playing a key role in the recruitment and differentiation of hMSCs. However, engineered biomaterials able to simultaneously direct hMSC fate and modulate macrophage phenotype have not yet been identified. A novel combinatorial chem.-topog. screening platform, the ChemoTopoChip, is used here to identify materials suitable for bone regeneration by screening 1008 combinations in each experiment for human immortalized mesenchymal stem cell (hiMSCs) and human macrophage response. The osteoinduction achieved in hiMSCs cultured on the “hit” materials in basal media is comparable to that seen when cells are cultured in osteogenic media, illustrating that these materials offer a materials-induced alternative to osteo-inductive supplements in bone-regeneration. Some of these same chem.-microtopog. combinations also exhibit immunomodulatory stimuli, polarizing macrophages towards a pro-healing phenotype. Maximum control of cell response is achieved when both chem. and topog. are recruited to instruct the required cell phenotype, combining synergistically. The large combinatorial library allows us for the first time to probe the relative cell-instructive roles of microtopog. and material chem. which we find to provide similar ranges of cell modulation for both cues. Machine learning is used to generate structure-activity relationships that identify key chem. and topog. features enhancing the response of both cell types, providing a basis for a better understanding of cell response to micro topog. patterned polymers.
2495-37-6, Benzyl methacrylate, also known as Benzyl methacrylate, is a useful research compound. Its molecular formula is C11H12O2 and its molecular weight is 176.21 g/mol. The purity is usually 95%.
Benzyl methacrylate is a chemical compound that belongs to the group of benzyl compounds. It has a copolymer structure with methyl ethyl methacrylate (MEMA) and hydroxyl groups. Benzyl methacrylate is produced by polymerization of benzyl chloride with allyl carbonate in the presence of radiation, forming a polymeric matrix. The morphology of this copolymer depends on the length of the benzyl chains and the concentration of MEMA., Recommanded Product: Benzyl methacrylate
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics