Zhou, Quan-Cheng;Wang, Tian-Rui;Li, Hui;Chen, Lei;Xin, Jia-Jin;Guo, Shen;Sheng, Gui-Hua;You, Zhong-Lu published 《Synthesis, crystal structures and insulin-like activity of three new oxidovanadium(V) complexes with aroylhydrazone ligand》 in 2019. The article was appeared in 《Journal of Inorganic Biochemistry》. They have made some progress in their research.Quality Control of Methyl 3-methylbenzoate The article mentions the following:
Three new oxidovanadium(V) complexes were designed, synthesized and characterized by C, H, N elemental anal., single crystal x-ray diffraction,UV/visible and IR spectra. Complex 1: [VOL1X] (H2L1 = (E)-N’-(2-hydroxybenzylidene)-3-methbenzohydrazide, HX = ethylmaltol = 2-ethyl-3-hydroxy-4-pyrone), Complex 2: [VOL2(CH3O)(CH3OH)], (H2L2 = C16H16N2O4 = (E)-N’-(2-hydroxybenzylidene)-3,5-dimethoxybenzohydrazide, CH3OH = methanol), Complex 3: [VOL3X] (H2L3 = (E)-N’-(3-ethoxy-2-hydroxybenzylidene)-3,5-dimethoxybenzohydrazide). The insulin-like activity of the three complexes was tested. Both normal and streptozotocin (STZ)-diabetic mice were administered intragastrically for two weeks. The complexes at doses of 10.0 and 5.0 mg V·kg-1 can significantly decrease the blood glucose level in STZ-diabetic mice, and the blood glucose level in the treated normal mice was not altered. The lesions of kidney and liver caused by diabetes have varying degrees of improvement. To complete the study, the researchers used Methyl 3-methylbenzoate (cas: 99-36-5) .
Methyl 3-methylbenzoate (cas: 99-36-5) is a common ester. Esters are widespread in nature and are widely used in industry. Several billion kilograms of polyesters are produced industrially annually, important products being polyethylene terephthalate, acrylate esters, and cellulose acetate.Quality Control of Methyl 3-methylbenzoate
Reference:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics