Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 2216-94-6, name is Ethyl phenylpropiolate, This compound has unique chemical properties. The synthetic route is as follows., Application In Synthesis of Ethyl phenylpropiolate
General procedure: The reaction was performed in a 20-mL round-bottomed flask equipped with a Teflon-coated magnetic stirrer bar. A solution of Pd(TPP) (3.6 mg, 0.005 mumol) and DMAP (0.01 mmol, 1.2 mg) in pyridine (1 mL) was stirred at 25 C for 0.5 h under H2(1 atm, balloon). A soln of alkyne 1(0.5 mmol) in pyridine (4 mL) was added,and the mixture was stirred for the indicated time. H2O (20 mL) was added, and the aqueous phase was extracted with EtOAc (3 ¡Á 50 mL). The organic phases were combined, dried (Na2SO4), and concentrated in vacuo. The residue was purified by flash column chromatography [silica gel (20 g, 2 ¡Á 15 cm), hexane-EtOAc (40:1)] to give an alkene 2.
Chemical properties determine the actual use. Each compound has specific chemical properties and uses. We look forward to more synthetic routes in the future to expand reaction routes of 2216-94-6.
Reference:
Article; Nishibayashi, Ryo; Kurahashi, Takuya; Matsubara, Seijiro; Synlett; vol. 25; 9; (2014); p. 1287 – 1290;,
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