Application In Synthesis of Dimethyl 5-aminoisophthalate. Recently I am researching about ONE-POT SYNTHESIS; P=C BONDS; PHOSPHORUS; CHEMISTRY; SEPARATION; MOLECULES; CAVITIES, Saw an article supported by the Royal SocietyRoyal Society of LondonEuropean Commission; University of Sussex. Published in AMER CHEMICAL SOC in WASHINGTON ,Authors: Pearce, KG; Crossley, IR. The CAS is 99-27-4. Through research, I have a further understanding and discovery of Dimethyl 5-aminoisophthalate
The condensation of MeP(SiMe3)(2) with a series of 5-substituted isophthaloyl chlorides (5-R’C6H3-2,6-{C(O)Cl}(2)) affords the diphosphametacyclophanes m-{-C(O)-C6H3-5-R’-(C(O)PMe)}(2) (R’ = I, Me, tBu, Ph, and p-NCC6H4); the analogues m-{-C(O)-C5H3N-(C(O)PMe)}(2) and m-{-C(O)-C6H4-(C(O)PPh)}(2) are similarly obtained in preference to higher oligomers, in contrast to precedent reports. The cyclophanes all adopt butterfly-like conformations in the solid state with the P-organyl substituents adopting mutually exo arrangements. Structural and computational data suggest the nature of the 5-R substituent is key in directing the inter-ring angle and the extent of LUMO stabilization about the diketophophanyl scaffold. The latter is substantiated by UV/vis spectroscopy and cyclic voltammetry, which demonstrate these cyclophanes to be appreciably comparable to the diketophosphanyl systems commonly explored in the context of organic electronic materials; intriguingly, the distinct dikeophosphanyl moieties within the macrocycles appear effectively insulated by the macrocycle geometry, rather than acting as a through-conjugate.
Application In Synthesis of Dimethyl 5-aminoisophthalate. About Dimethyl 5-aminoisophthalate, If you have any questions, you can contact Pearce, KG; Crossley, IR or concate me.
Reference:
Patent; ASTRA ZENECA AB; NPS PHARMACEUTICALS, INC.; WO2004/14881; (2004); A2;,
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics